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Dietary supplement

Osha Root Rocky Mountain Throat Syrup Ingredients & Drug Interactions

by Herbs Etc.

Osha Root Rocky Mountain Throat Syrup label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Oct 7, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Osha Root Rocky Mountain Throat Syrup against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Osha Root Rocky Mountain Throat Syrup is a dietary supplement by Herbs Etc. with 1 active ingredient. Its ingredients are commonly taken for cough and sore throat, respiratory infections and colds, immune support.Based on those ingredients, 717 medications have a known interaction with it, the most serious rated moderate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Osha Root Rocky Mountain Throat Syrup by Herbs Etc.

Ask about any prescription or over-the-counter medication and we check it for interactions with Osha Root Rocky Mountain Throat Syrup by Herbs Etc. — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Osha Root Rocky Mountain Throat Syrup by Herbs Etc.

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Oct 6, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 5 active ingredients.
  • “Proprietary Extract Blend” is a proprietary blend — the label gives one combined amount (5 mL) without saying how much of each component you get.
  • “Osha root extract” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.

This is a 5-ingredient liquid syrup. The active components are a proprietary blend containing Osha root extract, plus individual extracts of White Pine bark, Wild Cherry bark, Spikenard root, Balsam Poplar bud, and Bloodroot root.

The liquid base includes sugar cane juice, purified water, glycerine, and alcohol as inactive ingredients to preserve and deliver the herbal extracts.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: soothing cough syrup promoting respiratory health.
  • We looked for evidence on: Asthma, Bronchitis, Common cold, Cough, sore throat, upper respiratory infection — and 1 related terms.
  • The closest evidence on file: American Spikenard is rated "Insufficient Reliable Evidence To Rate" for Asthma (Natural Medicines).
  • Also on file: American Spikenard is rated "Insufficient Reliable Evidence To Rate" for Common cold.
  • Also on file: Wild Cherry is rated "Insufficient Reliable Evidence To Rate" for Bronchitis, Common cold, Cough.

The evidence for this syrup's effectiveness is not established in the data we hold. Wild Cherry has insufficient reliable evidence for bronchitis, common cold, and cough.

Spikenard root extract shows insufficient evidence for asthma and common cold. Bloodroot is possibly effective for dental plaque and gingivitis, but that's a dental use, not a throat or respiratory one.

For the product's intended throat-support purpose, we don't have effectiveness ratings that apply.

The evidence, ingredient by ingredient Osha

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

This product carries several safety red flags you should know about. Wild Cherry bark contains cyanide-forming compounds and is generally considered safe only in the small amounts found in commercial cough products — large doses can cause cyanide toxicity, which can be serious or fatal.

Spikenard root extract is not well studied in modern research and should be used cautiously and short-term only. Bloodroot root extract is potentially toxic and corrosive and is not recommended for self-treatment; the product carries risks of nausea, vomiting, and central nervous system depression at higher doses, and topical contact can cause severe skin damage and scarring.

During pregnancy, Wild Cherry is rated likely unsafe, and Spikenard is possibly unsafe. Bloodroot is rated likely unsafe in pregnancy.

While breastfeeding, the safety data advises against all three: Wild Cherry, Spikenard, and Bloodroot. If you're pregnant or breastfeeding, talk with your doctor or pharmacist about whether this product is appropriate for you.

Side effects, ingredient by ingredient Osha

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 3 matched ingredients can interact with medications — American Spikenard, Wild Cherry.
  • The most serious interaction on file is rated Moderate.
  • For scale: 718 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before using this syrup if you take any medications metabolized by the liver enzyme CYP3A4, such as lovastatin or ketoconazole (Moderate severity). Also double-check if you take diuretic drugs like furosemide or hydrochlorothiazide (Minor severity).

No interactions are documented for the other ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This syrup combines several herbal extracts with limited evidence of effectiveness and some notable safety concerns, particularly around bloodroot's toxicity and wild cherry's cyanide content at higher doses. If you take medications — especially ones broken down by your liver (like cholesterol drugs or antifungals) or diuretics — check your exact medications with the tool on this page before using it.

Pregnant or breastfeeding people should talk with their doctor or pharmacist first, as the safety data does not support use during these times.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Osha Root Rocky Mountain Throat Syrup, straight from the product label.

Brand Herbs Etc.
Net contents 4 Fluid Ounce(s); 118 mL
Market status On market
Date entered into DSLD Jan 23, 2025
DSLD ID 320874
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Vegan, Vegetarian, Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Osha Root Rocky Mountain Throat Syrup by Herbs Etc., sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
5 mL, 2.5 mL, 1.25 mL
Maximum serving Sizes:
5 mL, 2.5 mL, 1.25 mL
Servings per container
23
IngredientAmount% DV
Calories10 Calorie(s)--
Total Carbohydrates3 Gram(s)1%
Added Sugars3 Gram(s)6%
Total Sugars3 Gram(s)--
Proprietary Extract Blend5 mL--
Osha root extract0 NP--
White Pine bark extract0 NP--
Wild Cherry bark extract0 NP--
Spikenard root extract0 NP--
Balsam Poplar Bud Extract0 NP--
Bloodroot Root Extract0 NP--

Other ingredients: Sugar Cane Juice, Evaporated, Water, Purified, Glycerine, Alcohol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Herbal medicine Soothing cough syrup for adults and children Deliciously powerful formula comforts the throat Promotes sinus, throat, bronchiole and lung health

Gluten free

Vegan

Sinuses Throat Bronchioles Lungs Powerful respiratory support Rocky Mountain Throat Syrup is a powerful cough syrup that soothes and comforts throat tissues. This formula promotes sinus, throat, bronchiole and lung health.

No artificial sweeteners, corn syrup, colors or flavors added. No preservatives. Gluten free

Vegan

Manufactured in Santa Fe, NM.

Seals/Symbols

Vegan

FDA Statement of Identity

Herbal Supplement

Brand IP Statement(s)

Herbal Medicines Made Right We do all of this to bring you herbal medicines made right. Daniel Gagnon Medical herbalist and president of Herbs, Etc.

General Statements

We apply our company philosophy to Rocky Mountain Throat Syrup, as we do to all of our herbal medicines. That philosophy is to do what's right, which extends to identifying and choosing the right herbs, using the right machines and processes and making the right liquid extracts. We focus solely on providing you with the right active constituent-rich formulations that support your health needs. Each herbal medicine is released only after it goes through rigorous quality control to ensure safety and satisfaction.

Facebook.com/herbsetc

Formula

Osha root, an important ingredient in this herbal medicine, has been used by generations of Southwestern Native Americans and Hispanics to support their respiratory health. We believe Osha root is the must-have herb, which is why we include it in our throat syrup. Our commitment to Osha root goes beyond our belief in its medicinal qualities. Herbs, Etc. works with plant preservationists to ensure the sustainability of this important botanical. Learn more about this ongoing project by visiting Herbs, Etc.'s Rocky Mountain Throat Syrup pages at herbsetc.com.

Soothing cough syrup for adults and children

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent disease.

Suggested/Recommended/Usage/Directions

Suggested use: Adults and children 12 years of age and older: Take 1 teaspoon every 3 hours. Children 5-12 years of age: Take 1/2 teaspoon every 3 hours. Children 2-5 years of age: Take 1/4 teaspoon every 3 hours.

Precautions

Children younger than 2 years of age: Consult a healthcare provider before using.

Caution: Do not use during pregnancy.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Osha Root Rocky Mountain Throat Syrup by Herbs Etc. label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Osha Root Rocky Mountain Throat Syrup label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Osha Root Rocky Mountain Throat Syrup by Herbs Etc.

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size5 mL Dosage formLiquid Servings per container23 Amounts shown are per serving.

Proprietary Extract Blend

5 mL per serving

Other (inactive) ingredients: Sugar Cane Juice, Evaporated, Water, Purified, Glycerine, Alcohol. These complete the product’s ingredient list but are not active constituents.

Interaction report

Osha Root Rocky Mountain Throat Syrup by Herbs Etc. Drug Interactions

Want to check YOUR meds against Osha Root Rocky Mountain Throat Syrup?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
717Drugs
645 Moderate 72 Minor

Ingredients driving the most interactions

Individual Drug Interactions

The ingredients in Osha Root Rocky Mountain Throat Syrup interact with 717 drugs. Click any drug to see the details.

0 of the 1 ingredient in Osha Root Rocky Mountain Throat Syrup interact with drugs. Each result below shows which ingredient is responsible.

Each ingredient & the kinds of drugs it affects

For each ingredient in Osha Root Rocky Mountain Throat Syrup with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

The maker

Brand information

Manufacturer and brand details for Osha Root Rocky Mountain Throat Syrup, from the product label.

Herbs Etc.

Name
Herbs, Etc., Inc.
Street Address
1340 Rufina Circle
City
Santa Fe
State
NM
ZipCode
87507
Web Address
www.herbsetc.com
Pharmacist Counseling Corner

Osha Root Rocky Mountain Throat Syrup by Herbs Etc.: Common Questions

Does Osha Root Rocky Mountain Throat Syrup by Herbs Etc. interact with any medications?
Yes. Based on its ingredients, Osha Root Rocky Mountain Throat Syrup has a known interaction with 717 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Osha Root Rocky Mountain Throat Syrup contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I use this if I take a statin or blood pressure medication?
Check the specific name with your pharmacist or doctor first. Some statins like lovastatin are metabolized by CYP3A4, and wild cherry in this syrup might raise their levels in your body. Diuretics used for blood pressure also warrant a pre-use conversation. Your pharmacist can run your exact medications through the interaction tool on this page.
Is this safe for a sore throat or cough?
We don't have evidence in our data that this syrup is effective for cough or sore throats. While wild cherry and other ingredients are traditional remedies for throat issues, the evidence to back that up hasn't been established. Talk with your pharmacist or doctor about what might actually help your symptoms.
Can I use this while pregnant or breastfeeding?
No. The safety data advises against this product during both pregnancy and while breastfeeding — wild cherry is rated likely unsafe in pregnancy, spikenard is possibly unsafe, and bloodroot is rated likely unsafe. Talk with your doctor or midwife about safer options for throat support during these times.
What's bloodroot doing in a throat syrup?
Bloodroot is included as an extract, likely for traditional antimicrobial properties. However, bloodroot is potentially toxic and corrosive, and we don't recommend it for self-treatment. At higher doses or with long-term use, it can cause nausea, vomiting, and serious side effects. This is one reason to talk with your pharmacist before using this product.
Are there any fillers or artificial ingredients?
The inactive ingredients are sugar cane juice, purified water, glycerine, and alcohol — all are used to preserve and deliver the herbal extracts in liquid form. No artificial additives are listed.
What's spikenard root for?
Spikenard root extract is traditionally used for cold and respiratory symptoms, but the evidence is insufficient to confirm it works. It's believed to promote sweating, which is why it can enhance the effects of diuretic medications — another reason to check with your pharmacist if you take water pills.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Osha Root Rocky Mountain Throat Syrup label
Go deeper

The Full Monographs Behind Osha Root Rocky Mountain Throat Syrup’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Osha

Osha is a root from a wild mountain plant native to the western United States and Mexico, traditionally used by Native American and Hispanic communities for coughs, colds, and sore throats....

Read the full Osha monograph →
Sources

Sources & How We Checked

Osha Root Rocky Mountain Throat Syrup's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 21 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Osha 2 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.

See these in context on the Osha monograph →

Wild Cherry 4 references
  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  3. Budzinski JW, Foster BC, Vandenhoek S, Arnason JT. An in vitro evaluation of human cytochrome P450 3A4 inhibition by selected commercial herbal extracts and tinctures. Phytomedicine 2000;7:273-82. PubMed
  4. Pentore, R., Venneri, A., and Nichelli, P. Accidental choke-cherry poisoning: early symptoms and neurological sequelae of an unusual case of cyanide intoxication. Ital.J Neurol.Sci. 1996;17(3):233-235. PubMed

See these in context on the Wild Cherry monograph →

American Spikenard 1 reference
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.

See these in context on the American Spikenard monograph →

Bloodroot 14 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  3. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  4. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  5. Eversole, L. R., Eversole, G. M., and Kopcik, J. Sanguinaria-associated oral leukoplakia: comparison with other benign and dysplastic leukoplakic lesions. Oral Surg.Oral Med.Oral Pathol.Oral Radiol.Endod. 2000;89(4):455-464. PubMed
  6. Allen, C. L., Loudon, J., and Mascarenhas, A. K. Sanguinaria-related leukoplakia: epidemiologic and clinicopathologic features of a recently described entity. Gen.Dent. 2001;49(6):608-614.
  7. Kuftinec, M. M., Mueller-Joseph, L. J., and Kopczyk, R. A. Sanguinaria toothpaste and oral rinse regimen clinical efficacy in short- and long-term trials. J.Can.Dent.Assoc. 1990;56(7 Suppl):31-33.
  8. Frankos, V. H., Brusick, D. J., Johnson, E. M., Maibach, H. I., Munro, I., Squire, R. A., and Weil, C. S. Safety of Sanguinaria extract as used in commercial toothpaste and oral rinse products. J.Can.Dent.Assoc. 1990;56(7 Suppl):41-47.
  9. Cullinan, M. P., Powell, R. N., Faddy, M. J., and Seymour, G. J. Efficacy of a dentifrice and oral rinse containing sanguinaria extract in conjunction with initial periodontal therapy. Aust.Dent.J. 1997;42(1):47-51. PubMed
  10. Affleck, A. G. and Varma, S. A case of do-it-yourself Mohs' surgery using bloodroot obtained from the internet. Br.J Dermatol 2007;157(5):1078-1079. PubMed
  11. Cienki JJ, Zaret L. An Internet misadventure: bloodroot salve toxicity. J Altern Complement Med. 2010;16(10):1125-7. PubMed
  12. Hou JL, Brewer JD. Black salve and bloodroot extract in dermatologic conditions. Cutis. 2015;95(6):309-11.
  13. Schilling LM, Saedi N. Bloodroot paste: what dermatologists and patients need to know. Dermatol Surg 2016;42(10):1223-4. PubMed
  14. Schlichte MJ, Downing CP, Ramirez-Fort M, Gordon R, Tyring S. Bloodroot associated eschar. Dermatol Online J 2014;20(7). DOI

See these in context on the Bloodroot monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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