Pancreatic Enzyme Formula Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Pancreatic Enzyme Formula against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Pancreatic Enzyme Formula is a dietary supplement by Pure Encapsulations with 3 active ingredients. Its ingredients are commonly taken for digestion and bloating, muscle soreness and exercise recovery, inflammation and swelling.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Pancreatic Enzyme Formula by Pure Encapsulations
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
This formula contains 3 active digestive enzymes: amylase (which breaks down carbohydrates), protease (which breaks down proteins), and lipase (which breaks down fats). These are the same kinds of enzymes your pancreas naturally makes.
Pancreatin, listed as one ingredient, is actually a blend of these three component enzymes — so the product delivers them together as they work in your body. The capsule itself is vegetarian, and the formula also contains hypoallergenic plant fiber as a filler.
Does it work?
Not established
The evidence we hold doesn't establish how well these individual enzymes work for digestive support or any specific condition. Lipase has been studied for inflammatory bowel disease (IBD) and indigestion, but the data rates both as having insufficient reliable evidence.
We don't have effectiveness information for amylase or protease in our records.
How safe is it?
Well-documented data
Protease and lipase are generally well tolerated in adults, though some people report mild digestive upset or, rarely, allergic reactions. Protease can occasionally trigger allergic responses — occupational exposure to airborne proteolytic enzymes has rarely caused allergic rhinitis or asthma in workers.
We couldn't check amylase safety data. For pregnancy: the safety data advises against protease unless your doctor prescribes it.
For lipase and amylase in pregnancy, there isn't enough data to know either way — talk with your doctor if you're pregnant or breastfeeding. The same goes for breastfeeding with protease — there's little data, so check with your healthcare provider first.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredients we were able to check. Still, it's smart to confirm with your own pharmacist or doctor that this enzyme formula won't interfere with how your medications are absorbed.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.
This product is a straightforward blend of digestive enzymes for people whose pancreas may not be making enough on its own. It's generally well tolerated, but anyone with a serious digestive condition should use it only under medical guidance.
If you're pregnant or breastfeeding, talk it over with your doctor or pharmacist first — the safety data varies by ingredient.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Pancreatic Enzyme Formula, straight from the product label.
| Brand | Pure Encapsulations |
|---|---|
| Barcode (UPC) | 766298002149 |
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Nov 22, 2022 |
| DSLD ID | 278020 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Pancreatic Enzyme Formula by Pure Encapsulations, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Amylase | 0 NP | -- |
| Protease | 0 NP | -- |
| Lipase | 0 NP | -- |
| Pancreatin | 500 mg | -- |
Other ingredients: Vegetarian Capsule, hypoallergenic Plant Fiber
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Storage
Store in a cool, dry place.
Suggested/Recommended/Usage/Directions
Recommendations: As a dietary supplement, take 1 capsule, 3 times daily, with each meal, or as directed by a health professional.
Precautions
Warning: If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.
Keep out of the reach of children.
General Statements
Scan to learn about our hypoallergenic supplements
Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity.
General
Use only if safety seal is intact.
Seals/Symbols
GFCO.org Certified Gluten-Free by the Gluten-Free Certification Organization, www.gluten.org
Formulation
Acid-resistant capsules; supports digestive function
Gluten-free, non-GMO & hypoallergenic
Gluten-free, non-GMO & hypoallergenic
FDA Statement of Identity
Dietary Supplement
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Pancreatic Enzyme Formula by Pure Encapsulations label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Pancreatic Enzyme Formula by Pure Encapsulations
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Other (inactive) ingredients: Vegetarian Capsule, Hypoallergenic Plant Fiber. These complete the product’s ingredient list but are not active constituents.
Pancreatic Enzyme Formula by Pure Encapsulations Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Pancreatic Enzyme Formula. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Pancreatic Enzyme Formula, from the product label.
Pure Encapsulations
See all Pure Encapsulations products- Name
- Pure Encapsulations
- Street Address
- 490 Boston Post Road
- City
- Sudbury
- State
- MA
- Phone Number
- 1-800-753-2277
- Web Address
- www.PureEncapsulations.com
Pancreatic Enzyme Formula by Pure Encapsulations: Common Questions
Does Pancreatic Enzyme Formula by Pure Encapsulations interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What does this pancreatic enzyme formula actually do?
Is it safe to take if I'm pregnant?
Can I take this while breastfeeding?
Does it really work for digestive problems?
Are there any side effects?
Does the formula contain fillers?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Pancreatic Enzyme Formula is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Pancreatic Enzyme Formula’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Proteolytic Enzymes (proteases)
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), trypsin, chymotrypsin, and pancreatin. Peo...
Read the full Proteolytic Enzymes (proteases) monograph → Herb & supplement monographLipase
Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy for people who cannot make enough of their...
Read the full Lipase monograph →Sources & How We Checked
Pancreatic Enzyme Formula's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 4 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Proteolytic Enzymes (proteases) 3 references
- Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
- Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
- Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed
See these in context on the Proteolytic Enzymes (proteases) monograph →
Lipase 1 reference
- Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC