No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

Pancreatic Enzyme Formula Ingredients & Drug Interactions

by Pure Encapsulations

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Pancreatic Enzyme Formula is a dietary supplement by Pure Encapsulations with 3 active ingredients. Its ingredients are commonly taken for digestion and bloating, muscle soreness and exercise recovery, inflammation and swelling.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Pancreatic Enzyme Formula by Pure Encapsulations

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 3 active ingredients.
  • “Pancreatin” is listed as a grouped ingredient — the label gives one combined amount (500 mg) without saying how much of each component you get.

This formula contains 3 active ingredients: amylase, protease, and lipase — all digestive enzymes that help break down food. The capsules also contain vegetarian capsule material and hypoallergenic plant fiber as inactive ingredients.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

The label doesn't state a purpose we can grade — see each ingredient's own graded uses on its monograph instead.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence isn't established in our data for these enzymes. Lipase has been studied for inflammatory bowel disease and dyspepsia (indigestion), but current evidence is insufficient to rate whether it works for those uses.

No effectiveness ratings are on file for amylase or protease in this product.

The evidence, ingredient by ingredient Proteolytic Enzymes (proteases) Lipase

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Protease and lipase are generally well tolerated in most adults, though digestive upset or allergic reactions can occur — rarely, occupational exposure to proteolytic enzymes has caused allergic reactions like allergic rhinitis or asthma. People with serious digestive conditions should use this formula only under medical guidance.

During pregnancy, the safety data advises against protease use unless prescribed by your doctor. For lipase in pregnancy, there's little safety data, so use only if your doctor advises it.

Breastfeeding safety hasn't been well studied for either enzyme — talk with your healthcare provider before using this product if you're nursing.

Side effects, ingredient by ingredient Proteolytic Enzymes (proteases) Lipase

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 2 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. That said, if you take any medications — especially those related to digestion, absorption, or blood clotting — run them through the checker on this page or confirm with your pharmacist before you start.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.

This is a digestive enzyme supplement for people who want support breaking down food. If you have a serious digestive condition, take medications regularly, or are pregnant or breastfeeding, check with your doctor or pharmacist before starting.

They can help you decide whether it's right for your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pancreatic Enzyme Formula, straight from the product label.

Brand Pure Encapsulations
Barcode (UPC) 766298002590
Net contents 180 Capsule(s)
Market status On market
Date entered into DSLD Nov 22, 2022
DSLD ID 278019
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pancreatic Enzyme Formula by Pure Encapsulations, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
180
UPC/BARCODE
766298002590
IngredientAmount% DV
Amylase0 NP--
Protease0 NP--
Lipase0 NP--
Pancreatin500 mg--

Other ingredients: Vegetarian Capsule, hypoallergenic Plant Fiber

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Storage

Store in a cool, dry place.

Suggested/Recommended/Usage/Directions

Recommendations: As a dietary supplement, take 1 capsule, 3 times daily, with each meal, or as directed by a health professional.

Precautions

Warning: If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.

Keep out of the reach of children.

Use only if safety seal is intact

General Statements

Scan to learn about our hypoallergenic supplements

Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity.

Seals/Symbols

GFCO.org Certified Gluten-free by the Gluten-Free Certification Organization, www.gluten.org

Formulation

Acid-resistant capsules; Supports digestive function

Gluten-free, non-GMO & hypoallergenic

Gluten-free, non-GMO & hypoallergenic

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

See for yourself

Pancreatic Enzyme Formula by Pure Encapsulations label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Pancreatic Enzyme Formula by Pure Encapsulations

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container180 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Pancreatin

500 mg per serving Form: Porcine

Other (inactive) ingredients: Vegetarian Capsule, Hypoallergenic Plant Fiber. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pancreatic Enzyme Formula by Pure Encapsulations Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Pancreatic Enzyme Formula. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Pancreatic Enzyme Formula, from the product label.

Pure Encapsulations

See all Pure Encapsulations products
Name
Pure Encapsulations
Street Address
490 Boston Post Road
City
Sudbury
State
MA
Phone Number
1-800-753-2277
Web Address
www.PureEncapsulations.com
Pharmacist Counseling Corner

Pancreatic Enzyme Formula by Pure Encapsulations: Common Questions

Does Pancreatic Enzyme Formula by Pure Encapsulations interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Pancreatic Enzyme Formula. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Pancreatic Enzyme Formula contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What does this formula do?
It contains three digestive enzymes — amylase, protease, and lipase — that help break down carbohydrates, proteins, and fats in food. People use pancreatic enzyme formulas when they want extra digestive support.
Can I take this if I'm pregnant?
The safety data advises against protease during pregnancy unless prescribed. Lipase has little safety data in pregnancy, so use only if your doctor advises it. Talk with your doctor before starting — they know your situation best.
Is it safe while breastfeeding?
Breastfeeding safety hasn't been well studied for protease or lipase. Check with your healthcare provider first before using this product if you're nursing.
What side effects might I notice?
Most people tolerate these enzymes well. Digestive upset or allergic reactions can occur. Rarely, occupational exposure to proteolytic enzymes has caused allergic reactions in sensitive people — talk to your pharmacist if you have a history of enzyme allergies.
Do these enzymes actually work for digestion?
The evidence in our data is insufficient to rate whether lipase works for conditions like indigestion or inflammatory bowel disease. No effectiveness ratings are on file for amylase or protease.
Is there anything else in the capsule besides the enzymes?
The capsules contain a vegetarian capsule material and hypoallergenic plant fiber as inactive ingredients — no other fillers.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pancreatic Enzyme Formula is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pancreatic Enzyme Formula label
Sources

Sources & How We Checked

Pancreatic Enzyme Formula's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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