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Dietary supplement

Inositol (Powder) Ingredients & Drug Interactions

by Pure Encapsulations

Inositol (Powder) label
See full label image
Powder Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Inositol (Powder) against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Inositol (Powder) is a dietary supplement by Pure Encapsulations with 1 active ingredient. Its ingredients are commonly taken for polycystic ovary syndrome (pcos), anxiety and panic, depression and mood.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Inositol. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Inositol (Powder) by Pure Encapsulations

Ask about any prescription or over-the-counter medication and we check it for interactions with Inositol (Powder) by Pure Encapsulations — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Inositol (Powder) by Pure Encapsulations

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: inositol, a naturally occurring compound that your body makes and that you also get from foods. In this form, you're getting it as a concentrated powder, which lets you adjust your dose easily.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Support for nervous tension and ovarian health.
  • We looked for evidence on: Anxiety, Panic disorder, Polycystic ovary syndrome (PCOS), Infertility, Mood support, Insulin sensitivity — and 1 related terms.
  • The strongest evidence on file: Inositol is rated "Possibly Effective" for Polycystic ovary syndrome (PCOS) (Natural Medicines).
  • Also on file: Inositol is rated "Possibly Ineffective" for Anxiety.
  • Also on file: Inositol is rated "Insufficient Reliable Evidence To Rate" for Panic disorder, Infertility.

Inositol is possibly effective for polycystic ovary syndrome (PCOS) and metabolic syndrome, according to the research we have. It's also possibly effective for preterm labor prevention.

For anxiety, diabetic nerve pain (neuropathy), and depression, the evidence suggests it's possibly ineffective — meaning research hasn't shown it works for those uses.

The evidence, ingredient by ingredient Inositol

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Inositol is generally well tolerated, with mild side effects limited mostly to digestion. The most common ones are diarrhea, gas, and nausea when taken by mouth.

In one research study, children taking inositol with omega-3 fatty acids reported cold and allergy symptoms, though it's unclear if inositol was the cause. Safety data in pregnancy and breastfeeding isn't fully established, so if you're pregnant or nursing, talk with your doctor or pharmacist before starting — don't use it on your own.

Side effects, ingredient by ingredient Inositol

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Inositol.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check all antidiabetes drugs (blood-sugar medications) before taking this — inositol lowers blood glucose and may heighten the risk of low blood sugar when combined with these medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Inositol makes sense if you're managing PCOS, metabolic syndrome, or preterm labor risk and want a well-tolerated option. If you take diabetes medication, check your specific drugs here first — the risk of low blood sugar is real.

Pregnant or nursing? Get personalized advice from your pharmacist before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 21, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Inositol (Powder), straight from the product label.

Brand Pure Encapsulations
Barcode (UPC) 766298011295
Net contents 8.8 Ounce(s); 252 Gram(s)
Market status On market
Date entered into DSLD Dec 21, 2024
DSLD ID 322381
Product type Non-nutrient/non-botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Inositol (Powder) by Pure Encapsulations, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
4.2 Gram(s)
Maximum serving Sizes:
4.2 Gram(s)
Servings per container
60
UPC/BARCODE
766298011295
IngredientAmount% DV
Inositol4 Gram(s)--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Storage

Store in a cool, dry place.

Packaged by weight, not volume. Settling may occur.

Suggested/Recommended/Usage/Directions

Recommendations: As a dietary supplement, take 1 scoop, 1-2 times daily, mixed with water, with or between meals, or as directed by a health professional.

Precautions

Warning: If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.

Keep out of the reach of children.

Use only if safety seal is intact.

General Statements

Scan to learn about our hypoallergenic supplements

Formulation

Provides support for occasional nervous tension and ovarian health

Gluten-free, non-GMO & hypoallergenic

Gluten-free, non-GMO & hypoallergenic

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Inositol (Powder) by Pure Encapsulations label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Inositol (Powder) label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Inositol (Powder) by Pure Encapsulations

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size4.2 Gram(s) Dosage formPowder Servings per container60 Amounts shown are per serving.

Inositol

Interacts with
86 drugs
4 Gram(s) per serving Form: Myo-Inositol

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, m...

Inositol monograph & interactions
Interaction report

Inositol (Powder) by Pure Encapsulations Drug Interactions

Want to check YOUR meds against Inositol (Powder)?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Inositol 86

Individual Drug Interactions

The ingredients in Inositol (Powder) interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in Inositol (Powder) interact with drugs. Each result below shows which ingredient is responsible. Inositol

Each ingredient & the kinds of drugs it affects

For each ingredient in Inositol (Powder) with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Inositol1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that inositol lowers blood glucose levels and glycated hemoglobin (HbA1c) levels in patients with diabetes.

Likelihood Possible Evidence A
Inositol full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Inositol (Powder), from the product label.

Pure Encapsulations

See all Pure Encapsulations products
Name
Pure Encapsulations
Street Address
490 Boston Post Road
City
Sudbury
State
MA
Phone Number
1-800-753-2277
Web Address
www.PureEncapsulations.com
Pharmacist Counseling Corner

Inositol (Powder) by Pure Encapsulations: Common Questions

Does Inositol (Powder) by Pure Encapsulations interact with any medications?
Yes. Based on its ingredients, Inositol (Powder) has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Inositol (Powder) contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is inositol, and where does it come from?
Inositol is a compound your body naturally makes and that you get from foods. This powder is an isolated, concentrated form you can dose precisely.
Can I take this if I'm pregnant or breastfeeding?
Safety in pregnancy and breastfeeding isn't fully established. Talk with your doctor or pharmacist about whether it's right for you — don't start it on your own.
What side effects should I expect?
Most side effects are mild and digestive — diarrhea, gas, and nausea. These are the most common complaints in research.
Does inositol work for anxiety or depression?
Research shows it's possibly ineffective for both. If you're looking to manage either of those, inositol isn't the evidence-backed choice.
What conditions is inositol actually useful for?
The strongest evidence is for PCOS and metabolic syndrome, where it's rated possibly effective. It's also possibly effective for preterm labor prevention if that's relevant to you.
If I take diabetes medication, can I use this?
Inositol lowers blood glucose, so combined with diabetes drugs there's a risk of going too low. Check your exact medications with our tool first, and talk to your pharmacist about monitoring.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Inositol (Powder) is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Inositol (Powder) label
Go deeper

The Full Monographs Behind Inositol (Powder)’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Inositol

Interacts with 86 drugs

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, mood, and metabolic concerns. The stronge...

Read the full Inositol monograph →
Sources

Sources & How We Checked

Inositol (Powder)'s label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Inositol 14 references
  1. Palatnik A, Frolov K, Fux M, Benjamin J. Double-blind, controlled, crossover trial of inositol versus fluvoxamine for the treatment of panic disorder. J Clin Psychopharmacol 2001;21:335-9.. PubMed
  2. Allan SJ, Kavanagh GM, Herd RM, Savin JA. The effect of inositol supplements on the psoriasis of patients taking lithium: a randomized, placebo-controlled trial. Br J Dermatol 2004;150:966-9. PubMed
  3. Machado-Vieira R, Viale CI, Kapczinski F. Mania associated with an energy drink: the possible role of caffeine, taurine, and inositol. Can J Psychiatry 2001;46:454-5. PubMed
  4. Kamenov Z, Kolarov G, Gateva A, Carlomagno G, Genazzani AD. Ovulation induction with myo-inositol alone and in combination with clomiphene citrate in polycystic ovarian syndrome patients with insulin resistance. Gynecol Endocrinol 2015;31(2):131-5. PubMed
  5. Matarrelli B, Vitacolonna E, D'Angelo M, et al. Effect of dietary myo-inositol supplementation in pregnancy on the incidence of maternal gestational diabetes mellitus and fetal outcomes: a randomized controlled trial. J Matern Fetal Neonatal Med 2013;26(1 PubMed
  6. Mukai T, Kishi T, Matsuda Y, Iwata N. A meta-analysis of inositol for depression and anxiety disorders. Hum Psychopharmacol 2014;29(1):55-63. PubMed
  7. Farren M, Daly N, McKeating A, Kinsley B, Turner MJ, Daly S. The Prevention of Gestational Diabetes Mellitus With Antenatal Oral Inositol Supplementation: A Randomized Controlled Trial. Diabetes Care. 2017;40(6):759-63. PubMed
  8. Zheng X, Liu Z, Zhang Y, et al. Relationship Between Myo-Inositol Supplementary and Gestational Diabetes Mellitus: A Meta-Analysis. Medicine (Baltimore). 2015;94(42):e1604. PubMed
  9. Crawford TJ, Crowther CA, Alsweiler J, Brown J. Antenatal dietary supplementation with myo-inositol in women during pregnancy for preventing gestational diabetes. Cochrane Database Syst Rev. 2015;(12):CD011507. PubMed
  10. Maurizi AR, Menduni M, Del Toro R, et al. A pilot study of D-chiro-inositol plus folic acid in overweight patients with type 1 diabetes. Acta Diabetol. 2017;54(4):361-65. PubMed
  11. Leppink EW, Redden SA, Grant JE. A double-blind, placebo-controlled study of inositol in trichotillomania. Int Clin Psychopharmacol. 2017;32(2):107-14. PubMed
  12. Lam S, Mandrekar SJ, Gesthalter Y. A Randomized Phase IIb Trial of myo-Inositol in Smokers with Bronchial Dysplasia. Cancer Prev Res (Phila). 2016;9(12):906-14.
  13. Wozniak J, Faraone SV, Chan J, et al. A randomized clinical trial of high eicosapentaenoic acid omega-3 fatty acids and inositol as monotherapy and in combination in the treatment of pediatric bipolar spectrum disorders: a pilot study. J Clin Psychiatry. PubMed
  14. Vitale SG, Corrado F, Caruso S, et al. Myo-inositol supplementation to prevent gestational diabetes in overweight non-obese women: bioelectrical impedance analysis, metabolic aspects, obstetric and neonatal outcomes - a randomized and open-label, placebo-

See these in context on the Inositol monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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