No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

Pancreatic VegEnzymes Ingredients & Drug Interactions

by Pure Encapsulations

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Pancreatic VegEnzymes is a dietary supplement by Pure Encapsulations with 3 active ingredients. Its ingredients are commonly taken for digestive support, bloating and gas, fat digestion.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Pancreatic VegEnzymes by Pure Encapsulations

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 3 active ingredients.
  • “Proprietary Enzyme Blend” is a proprietary blend — the label gives one combined amount (200 mg) without saying how much of each component you get.

Pancreatic VegEnzymes contains three active digestive enzymes. Lipase breaks down fats, amylase breaks down carbohydrates, and protease 4.5 breaks down proteins—together they're meant to help your body digest food.

The inactive ingredients include a vegetarian capsule, tapioca dextrin, and ascorbyl palmitate (a form of vitamin C used as a preservative).

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

The label doesn't state a purpose we can grade — see each ingredient's own graded uses on its monograph instead.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for lipase and protease to treat inflammatory bowel disease (IBD) or dyspepsia (indigestion) is insufficient—we don't have enough reliable data to rate how well they work for these conditions. The product facts don't include effectiveness ratings for protease beyond that general caution, and no effectiveness data is on file for amylase.

If you're considering this product for a specific digestive issue, talk with your doctor or pharmacist about whether the evidence supports its use for your situation.

The evidence, ingredient by ingredient Lipase Proteolytic Enzymes (proteases)

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lipase and protease are generally well tolerated in adults when taken as supplements. Protease may rarely cause digestive upset or allergic reactions—occupational exposure to airborne protease has occasionally triggered allergic rhinoconjunctivitis (nasal and eye inflammation) or asthma, though this is rare with oral supplement use.

For pregnancy: The safety data on lipase and protease in pregnancy is limited, so use only if your doctor advises it. For breastfeeding: Safety while breastfeeding hasn't been well studied for either ingredient; check with your healthcare provider before taking it.

Lipase carries a particular caution in premature infants, though this applies to recombinant forms added to formula or breast milk, not oral supplements for adults.

Side effects, ingredient by ingredient Lipase Proteolytic Enzymes (proteases)

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 2 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. However, we hold no interaction data for amylase, so we cannot rule out interactions with that component.

If you take any medications, check your exact drugs through the search tool on this page or ask your pharmacist before you start.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Pancreatic VegEnzymes may appeal to you if you want plant-based digestive enzymes, though the evidence that they work for indigestion or inflammatory bowel disease isn't yet established. If you have a serious digestive condition, check with your doctor before starting it.

Anyone who is pregnant, breastfeeding, or taking medications should discuss this product with their own healthcare provider first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pancreatic VegEnzymes, straight from the product label.

Brand Pure Encapsulations
Barcode (UPC) 766298004792
Net contents 180 Capsule(s)
Market status On market
Date entered into DSLD Jan 23, 2023
DSLD ID 278021
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pancreatic VegEnzymes by Pure Encapsulations, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
180
UPC/BARCODE
766298004792
IngredientAmount% DV
Amylase0 NP--
Lipase0 NP--
Protease 4.50 NP--
Proprietary Enzyme Blend200 mg--

Other ingredients: Vegetarian Capsule, Tapioca Dextrin, Ascorbyl Palmitate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Storage

Store in a cool, dry place.

Suggested/Recommended/Usage/Directions

Recommendations: As a dietary supplement, take 1 capsule, 3 times daily, with each meal, or as directed by a health professional.

Precautions

Warning: If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.

Keep out of the reach of children.

Use only if safety seal is intact.

General Statements

Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity.

Scan to learn about our hypoallergenic supplements

Seals/Symbols

GFCO.org Certified Gluten-Free by the Gluten-Free Certification Organization, www.gluten.org

Formulation

Vegetarian formula to support digestive function

Gluten-free & Non-GMO

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

See for yourself

Pancreatic VegEnzymes by Pure Encapsulations label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Pancreatic VegEnzymes by Pure Encapsulations

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container180 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Enzyme Blend

200 mg per serving

Other (inactive) ingredients: Vegetarian Capsule, Tapioca Dextrin, Ascorbyl Palmitate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pancreatic VegEnzymes by Pure Encapsulations Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Pancreatic VegEnzymes. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Pancreatic VegEnzymes, from the product label.

Pure Encapsulations

See all Pure Encapsulations products
Name
Pure Encapsulations
Street Address
490 Boston Post Road
City
Sudbury
State
MA
Phone Number
1-800-753-2277
Web Address
www.PureEncapsulations.com
Pharmacist Counseling Corner

Pancreatic VegEnzymes by Pure Encapsulations: Common Questions

Does Pancreatic VegEnzymes by Pure Encapsulations interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Pancreatic VegEnzymes. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Pancreatic VegEnzymes contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help with my indigestion?
The evidence isn't established yet. Lipase and protease are included to support digestion, but we don't have reliable data showing they work for indigestion specifically. If indigestion is a real problem for you, talk with your doctor about what might help.
Can I take this if I'm pregnant?
There isn't enough safety data to know either way. The facts advise using lipase and protease only if your doctor recommends it during pregnancy. Talk with your healthcare provider about whether it's right for you.
What's the difference between these enzymes—why are there three?
Each one breaks down a different type of food: lipase breaks down fats, amylase breaks down carbohydrates, and protease breaks down proteins. Together they're meant to support your body's overall digestion of a mixed meal.
Are these enzymes natural?
The product name says VegEnzymes and uses a vegetarian capsule, suggesting plant-based or non-animal sources, but the product facts don't specify the source of each enzyme. If that matters to you, check the full label or contact the manufacturer.
Can I take this long-term?
The safety facts note that a thorough evaluation of long-term safety hasn't been conducted. If you're thinking of taking it regularly, especially if you have a digestive condition, check with your doctor first.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pancreatic VegEnzymes is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pancreatic VegEnzymes label
Sources

Sources & How We Checked

Pancreatic VegEnzymes's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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