No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Pantethine Ingredients & Drug Interactions

by AOR Advanced Orthomolecular Research Premium

Pantethine label
See full label image
Capsule Category: Vitamin
No known interaction
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Pantethine against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line No known interaction

Pantethine is a dietary supplement by AOR Advanced Orthomolecular Research Premium with 1 active ingredient. Its ingredients are commonly taken for general nutrition and energy, skin and hair health, acne (topical and oral).We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

Jump to a section

HelloPharmacist Scorecard of Pantethine by AOR Advanced Orthomolecular Research Premium

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: pantothenic acid, a B vitamin your body needs for energy metabolism and the health of your skin, hair, and digestive system. The capsule itself is made from microcrystalline cellulose and other inactive fillers like ascorbyl palmitate, silicon dioxide, and sodium stearyl fumarate.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Pantothenic Acid's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: cellular energy production and healthy cellular function.
  • We looked for evidence on: Chronic fatigue syndrome (CFS), Athletic performance, mitochondrial function, metabolic support.
  • The closest evidence on file: Pantothenic Acid is rated "Insufficient Reliable Evidence To Rate" for Athletic performance (Natural Medicines).
  • Also on file: Pantothenic Acid is rated "Insufficient Reliable Evidence To Rate" for Chronic fatigue syndrome (CFS).

Pantothenic acid is established as effective for treating pantothenic acid deficiency. For radiation dermatitis, the evidence suggests it's probably not effective.

For allergic rhinitis (hay fever), alopecia areata, and alcoholism, we don't have enough reliable evidence yet to rate whether it works. If you're thinking about this supplement for one of those less-studied uses, talk with your doctor about what the current evidence supports.

The evidence, ingredient by ingredient Pantothenic Acid

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Pantothenic acid taken by mouth is generally well tolerated, with diarrhea reported occasionally. When applied to skin, a synthetic form called dexpanthenol can cause itching, burning, irritation, contact dermatitis, or eczema in some people — a small number have reported allergic contact dermatitis.

In pregnancy and breastfeeding, typical dietary amounts and prenatal-vitamin doses are considered likely safe, but before taking high-dose supplements, check with your doctor.

Side effects, ingredient by ingredient Pantothenic Acid

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the pantothenic acid in this product. Because our monograph doesn't cover every possible interaction, run your exact medications through the checker on this page if you want to be thorough.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

This single-ingredient B vitamin is a straightforward choice if you're addressing a pantothenic acid deficiency or want basic B-vitamin support. It's generally well tolerated and has no documented medication interactions.

If you're pregnant, breastfeeding, or considering high doses, confirm the dose is right for you with your doctor or pharmacist.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 24, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pantethine, straight from the product label.

Brand AOR Advanced Orthomolecular Research Premium
Barcode (UPC) 624917080278
Net contents 90 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Mar 24, 2020
DSLD ID 214866
Product type Vitamin
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pantethine by AOR Advanced Orthomolecular Research Premium, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
90
UPC/BARCODE
624917080278
IngredientAmount% DV
Pantothenic Acid900 mg, 300 mg18000%, 6000%

Other ingredients: Microcrystalline Cellulose, Ascorbyl Palmitate, Silicon Dioxide, Capsule, Sodium Stearyl Fumarate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

GMP Manufacturing Quality assured Independent testing

Vegan

Non-GMO Gluten free

AOR guarantees that all ingredients have been declared on the label.

Contains no wheat, gluten, nuts, peanuts, sesame seeds, sulfites, mustard, soy, dairy, eggs, fish, shellfish or any animal byproduct.

Precautions

Do not use if safety seal is broken

Warning: Consult your physician if you are pregnant, lactating, if you have a medical condition, or if you’re taking any medication.

Keep out of reach of children.

To report a serious adverse event or obtain product information, call 1-866-215-0450

Storage

Store tightly sealed in a cool, dry place

Formula

Discussion: Pantethine, a biological metabolite of pantothenic acid (vitamin B5), is a precursor to coenzyme A, a critical factor in supporting the healthy function of many cellular pathways such as cellular energy production, the normal synthesis of numerous sex and adrenal hormones, and neurotransmitters.

Bioactive vitamin B5

Suggested/Recommended/Usage/Directions

Directions: Take 1 capsule 3 times daily with/without food, or as directed by a qualified health care practitioner.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

MyBlueprint

Product of Canada

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Pantethine by AOR Advanced Orthomolecular Research Premium label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Pantethine label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Pantethine by AOR Advanced Orthomolecular Research Premium

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Pantothenic Acid

No known
interactions
900 mg per serving Form: Pantethine, Vitamin B5

Pantothenic acid is vitamin B5, an essential nutrient your body uses to turn food into energy. True deficiency is very rare because it is found in nea...

Pantothenic Acid monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Ascorbyl Palmitate, Silicon Dioxide, Capsule, Sodium Stearyl Fumarate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pantethine by AOR Advanced Orthomolecular Research Premium Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Pantethine. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Pantethine, from the product label.

AOR Advanced Orthomolecular Research Premium

See all AOR Advanced Orthomolecular Research Premium products
Name
AOR Inc.
Street Address
30 Industrial West
City
Clifton
State
NJ
ZipCode
07012
Phone Number
1-866-215-0450
Pharmacist Counseling Corner

Pantethine by AOR Advanced Orthomolecular Research Premium: Common Questions

Does Pantethine by AOR Advanced Orthomolecular Research Premium interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Pantethine. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Pantethine contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while pregnant or breastfeeding?
The amounts in food and prenatal vitamins are considered likely safe in both pregnancy and lactation. If you're thinking about taking a supplement dose beyond that, talk with your doctor first to confirm what's right for you.
Will this help my hair grow back?
Pantothenic acid has been studied for alopecia areata, but we don't have enough reliable evidence yet to say whether it works. Your doctor can help you weigh this against other options if hair loss is a concern.
What's the difference between pantothenic acid and pantethine?
Pantethine is a form of pantothenic acid (also called vitamin B5). The product name uses 'Pantethine' but the active ingredient listed is pantothenic acid — they're related forms of the same B vitamin.
Can this give me diarrhea?
Diarrhea has been reported with pantothenic acid taken by mouth, though most people tolerate it well. If you develop loose stools after starting, that's worth mentioning to your pharmacist or doctor.
Does this interact with my blood pressure or diabetes medications?
No interactions are documented in our data for pantothenic acid with any medications. That said, run your specific drugs through the checker here, and if you want extra reassurance, a quick call to your pharmacist is never a bad idea.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pantethine is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pantethine label
Go deeper

The Full Monographs Behind Pantethine’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Pantothenic Acid

Pantothenic acid is vitamin B5, an essential nutrient your body uses to turn food into energy. True deficiency is very rare because it is found in nearly all foods, and most people meet thei...

Read the full Pantothenic Acid monograph →
Sources

Sources & How We Checked

Pantethine's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Pantothenic Acid 11 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  3. Debourdeau PM, Djezzar S, Estival JL, et al. Life-threatening eosinophilic pleuropericardial effusion related to vitamins B5 and H. Ann Pharmacother 2001;35:424-6. DOI
  4. Schmuth, M., Wimmer, M. A., Hofer, S., Sztankay, A., Weinlich, G., Linder, D. M., Elias, P. M., Fritsch, P. O., and Fritsch, E. Topical corticosteroid therapy for acute radiation dermatitis: a prospective, randomized, double-blind study. Br.J.Dermatol. 2 PubMed
  5. Schreck, U., Paulsen, F., Bamberg, M., and Budach, W. Intraindividual comparison of two different skin care conceptions in patients undergoing radiotherapy of the head-and-neck region. Creme or powder? Strahlenther.Onkol. 2002;178(6):321-329. PubMed
  6. Herbst, R. A., Uter, W., Pirker, C., Geier, J., and Frosch, P. J. Allergic and non-allergic periorbital dermatitis: patch test results of the Information Network of the Departments of Dermatology during a 5-year period. Contact Dermatitis 2004;51(1):13-1 PubMed
  7. Champault, G. and Patel, J. C. [Treatment of constipation with Bepanthene]. Med.Chir Dig. 1977;6(1):57-59.
  8. Scott LN, Fiume M, Bergfeld WF, et al. Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics. Int J Toxicol 2022;41(3_suppl):77-128. PubMed
  9. Han J, Warshaw EM. Allergic Contact Dermatitis to Panthenol in "Hypoallergenic" Products. Dermatitis 2023;34(1):62-63. PubMed
  10. Blanchard G, Kerre S, Walker A, et al. Allergic contact dermatitis from pantolactone and dexpanthenol in wound healing creams. Contact Dermatitis 2022;87(5):468-471. PubMed
  11. Peltier E, Trapp S, de Salvo R, et al. A new dexpanthenol-containing liquid cleanser for atopic-prone skin: Results from two prospective clinical studies evaluating cutaneous tolerability, moisturization potential, and effects on barrier function. J Cosme PubMed

See these in context on the Pantothenic Acid monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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