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Dietary supplement

Pau D'Arco Liquid Extract Ingredients & Drug Interactions

by BIOVEA

Pau D'Arco Liquid Extract label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Pau D'Arco Liquid Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Pau D'Arco Liquid Extract is a dietary supplement by BIOVEA with 1 active ingredient. Its ingredients are commonly taken for infections (bacterial, fungal, yeast), inflammation, immune support.Based on those ingredients, 122 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Pau d'Arco inner bark extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Pau D'Arco Liquid Extract by BIOVEA

Ask about any prescription or over-the-counter medication and we check it for interactions with Pau D'Arco Liquid Extract by BIOVEA — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Pau D'Arco Liquid Extract by BIOVEA

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: pau d'arco inner bark extract, a substance derived from the inner bark of the pau d'arco tree. The extract is suspended in a liquid base made from alcohol and purified water.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Pau D'arco product and its label doesn't state a use — see Pau D'arco's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence on pau d'arco for its traditional uses — cancer, peptic ulcers, wound healing, and dysmenorrhea (painful periods) — is insufficient to establish whether it works. We don't have reliable data in our records to say it's effective for any of these.

The evidence, ingredient by ingredient Pau D'arco

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Pau d'arco is generally well tolerated at typical doses, but human safety data is limited and side effects are more likely at higher doses. At doses of lapachol (a pau d'arco component) above 1.5 grams daily, the adverse effects documented include anemia, increased bleeding risk, severe nausea, vomiting, and diarrhea.

The safety data advises against use during pregnancy because of possible harm to the developing baby and lack of adequate safety information. There isn't enough data to know whether it's safe while breastfeeding — talk with your doctor or pharmacist for personalized guidance.

Side effects, ingredient by ingredient Pau D'arco

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Pau D'arco.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 122 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, double-check with your doctor or pharmacist if you're on any blood thinners (anticoagulants) or antiplatelet drugs — that includes warfarin, dabigatran, rivaroxaban, apixaban, clopidogrel, ticagrelor, aspirin, and many others. Pau d'arco may increase your bleeding risk when combined with these medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Pau d'arco extract may be worth considering if you're interested in its traditional uses and you're not taking blood thinners or antiplatelet medications. If you do take any blood thinner — whether prescription, over-the-counter like aspirin, or herbal — you should check with your doctor or pharmacist before starting this product.

Pregnant or breastfeeding people should avoid it, and anyone using it should stay well below 1.5 grams daily of the lapachol component to reduce the risk of serious side effects.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 22, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pau D'Arco Liquid Extract, straight from the product label.

Brand BIOVEA
Barcode (UPC) 689076046008
Net contents 118 mL; 4 fl. Oz.
Market status On market
Date entered into DSLD May 22, 2015
DSLD ID 45413
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pau D'Arco Liquid Extract by BIOVEA, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.5 tsp
Maximum serving Sizes:
1 tsp
Servings per container
23
UPC/BARCODE
689076046008
IngredientAmount% DV
Pau d'Arco inner bark extract5 mL--

Other ingredients: Alcohol, purified Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Vegan Product

Suggested/Recommended/Usage/Directions

Suggested Daily Intake: Mix 1/2 to 1 teaspoon of this natural extract into tea or juice to drink between meals.

General Statements

guaranteed premium quality

herb

FDA Statement of Identity

dietary supplement

Precautions

Warning: If you are pregnant, may become pregnant, or breastfeeding, consult your health care professional before using this product.

KEEP OUT OF REACH OF CHILDREN.

Do not use this product if the safety seal on the bottle is broken.

Storage

Store in a cool, dry place.

Seals/Symbols

MADE IN THE USA

GMP COMPLIANT

General

K14

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Pau D'Arco Liquid Extract by BIOVEA label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Pau D'Arco Liquid Extract label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Pau D'Arco Liquid Extract by BIOVEA

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.5 tsp Dosage formLiquid Servings per container23 Amounts shown are per serving.

Pau d'Arco inner bark extract

Interacts with
122 drugs
5 mL per serving

Pau d'arco is a South American tree bark traditionally used for infections and inflammation, and it contains compounds like lapachol that show activit...

Pau d'Arco inner bark extract monograph & interactions

Other (inactive) ingredients: Alcohol, Purified Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pau D'Arco Liquid Extract by BIOVEA Drug Interactions

Want to check YOUR meds against Pau D'Arco Liquid Extract?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
122Drugs
122 Moderate

Ingredients driving the most interactions

Pau d'Arco inner bark extract 122

Individual Drug Interactions

The ingredients in Pau D'Arco Liquid Extract interact with 122 drugs. Click any drug to see the details.

1 of the 1 ingredient in Pau D'Arco Liquid Extract interact with drugs. Each result below shows which ingredient is responsible. Pau d'Arco inner bark extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Pau D'Arco Liquid Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Pau d'Arco inner bark extract1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, pau d'arco might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research shows that pau d'arco reduces platelet aggregation and may interfere with vitamin K. One clinical study shows that taking the lapachol constituent of pau d'arco in doses above 1.5 grams daily increases the risk of bleeding. The effects of whole pau d'arco or pau d'arco extract in humans are unclear.

Likelihood Possible Evidence D
Pau d'Arco inner bark extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Pau D'Arco Liquid Extract, from the product label.

BIOVEA

See all BIOVEA products
Name
BIOVEA
Phone Number
1-800-961-4750
Web Address
www.biovea.com
Pharmacist Counseling Corner

Pau D'Arco Liquid Extract by BIOVEA: Common Questions

Does Pau D'Arco Liquid Extract by BIOVEA interact with any medications?
Yes. Based on its ingredients, Pau D'Arco Liquid Extract has a known interaction with 122 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Pau D'Arco Liquid Extract contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on aspirin?
Aspirin is an antiplatelet drug, and pau d'arco may increase bleeding risk when taken together. You should check with your doctor or pharmacist before combining them — they can weigh your individual situation and advise you on whether it's safe.
What does pau d'arco actually do?
Pau d'arco has been used traditionally for cancer, peptic ulcers, wound healing, and painful periods, but the evidence to prove it works for any of these is insufficient. The research isn't strong enough yet to say whether it's truly effective.
Is it safe to take long-term?
Human safety data on pau d'arco is limited. At high doses — specifically above 1.5 grams daily of its lapachol component — it can cause anemia, bleeding problems, and severe digestive upset. At typical doses it's generally well tolerated, but stick to lower amounts and talk with your pharmacist about how long you plan to use it.
Can I take this while pregnant?
No. The safety data advises against pau d'arco during pregnancy because of possible harm to the developing baby and lack of adequate safety information.
Can I take this while breastfeeding?
There isn't enough safety data to know whether pau d'arco is safe while breastfeeding. Talk with your doctor or pharmacist about your individual situation.
What's in this liquid besides the extract?
The product contains alcohol and purified water as the inactive base ingredients that carry the pau d'arco extract.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pau D'Arco Liquid Extract is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pau D'Arco Liquid Extract label
Go deeper

The Full Monographs Behind Pau D'Arco Liquid Extract’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Pau D'arco

Interacts with 122 drugs

Pau d'arco is a South American tree bark traditionally used for infections and inflammation, and it contains compounds like lapachol that show activity in lab studies. However, strong human...

Read the full Pau D'arco monograph →
Sources

Sources & How We Checked

Pau D'Arco Liquid Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Pau D'arco 6 references
  1. Gómez Castellanos JR, Prieto JM, Heinrich M. Red Lapacho (Tabebuia impetiginosa)--a global ethnopharmacological commodity? J Ethnopharmacol 2009;121:1-13. PubMed
  2. Guerra, Mde O., Mazoni, A. S., Brandao, M. A., and Peters, V. M. Toxicology of Lapachol in rats: embryolethality. Braz.J Biol. 2001;61(1):171-174. PubMed
  3. Felicio, A. C., Chang, C. V., Brandao, M. A., Peters, V. M., and Guerra, Mde O. Fetal growth in rats treated with lapachol. Contraception 2002;66(4):289-293. PubMed
  4. Son, D. J., Lim, Y., Park, Y. H., Chang, S. K., Yun, Y. P., Hong, J. T., Takeoka, G. R., Lee, K. G., Lee, S. E., Kim, M. R., Kim, J. H., and Park, B. S. Inhibitory effects of Tabebuia impetiginosa inner bark extract on platelet aggregation and vascular s
  5. Block JB, Serpick AA, Miller W, Wiernik PH. Early clinical studies with lapachol (NSC-11905). Cancer Chemother Rep 2. 1974;4(4):27-8.
  6. Algranti E, Mendonça EM, Ali SA, Kokron CM, Raile V. Occupational asthma caused by Ipe (Tabebuia spp) dust. J Investig Allergol Clin Immunol 2005;15(1):81-3.

See these in context on the Pau D'arco monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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