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Dietary supplement

PauD'Arco Alcohol Free Ingredients & Drug Interactions

by Brainchild Nutritionals

PauD'Arco Alcohol Free label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking PauD'Arco Alcohol Free against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

PauD'Arco Alcohol Free is a dietary supplement by Brainchild Nutritionals with 1 active ingredient. Its ingredients are commonly taken for infections (bacterial, fungal, yeast), inflammation, immune support.Based on those ingredients, 122 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Pau d' Arco bark extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against PauD'Arco Alcohol Free by Brainchild Nutritionals

Ask about any prescription or over-the-counter medication and we check it for interactions with PauD'Arco Alcohol Free by Brainchild Nutritionals — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of PauD'Arco Alcohol Free by Brainchild Nutritionals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.

This product contains one active ingredient: pau d'arco bark extract. The rest is water, purified water, and glycerin — inactive ingredients that keep the liquid stable and mixable.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Pau D'arco product and its label doesn't state a use — see Pau D'arco's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for pau d'arco is limited. Our data rates it as having insufficient reliable evidence for cancer, peptic ulcers, wound healing, and dysmenorrhea — meaning the research so far doesn't clearly show whether it works for these uses.

If you're considering it for one of these reasons, talk with your pharmacist about what the current science actually supports.

The evidence, ingredient by ingredient Pau D'arco

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Pau d'arco may cause side effects at higher doses, and human safety data is sparse. At doses above 1.5 grams daily of its lapachol component, it may cause anemia, increased bleeding risk, severe nausea, vomiting, and diarrhea.

The safety data advises against use during pregnancy due to possible harm to a developing baby and lack of safety information. It's also not recommended while breastfeeding because there isn't enough data to know it's safe.

Side effects, ingredient by ingredient Pau D'arco

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Pau D'arco.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 122 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Double-check this product before taking it if you're on any blood thinner (anticoagulant) like warfarin, dabigatran, or apixaban, or any antiplatelet drug like clopidogrel or aspirin. A Moderate interaction is documented, and it may increase bleeding risk.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Pau d'arco is worth considering only if you're not on blood thinners or antiplatelet medications. If you take any of those drugs, check with your pharmacist first — the bleeding risk is real.

Pregnant women and those breastfeeding should avoid it. The evidence for what it actually treats is thin, so be clear on why you want to use it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 21, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about PauD'Arco Alcohol Free, straight from the product label.

Brand Brainchild Nutritionals
Net contents 2 Ounce(s); 60 mL
Market status On market
Date entered into DSLD May 21, 2025
DSLD ID 328561
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Children (All)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for PauD'Arco Alcohol Free by Brainchild Nutritionals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1.5 mL
Maximum serving Sizes:
1.5 mL
Servings per container
40
IngredientAmount% DV
Pau d' Arco bark extract0 NP--

Other ingredients: Water, Purified, Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, apply 30 drops in water 3 times a day. Children: half of adult dose. Shake well before use.

Precautions

Note: May thin blood, Consult practitioner if using blood thinners.

Storage

Refrigerate after opening

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

PauD'Arco Alcohol Free by Brainchild Nutritionals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

PauD'Arco Alcohol Free label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in PauD'Arco Alcohol Free by Brainchild Nutritionals

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1.5 mL Dosage formLiquid Servings per container40 Amounts shown are per serving.

Pau d' Arco bark extract

Interacts with
122 drugs
0 NP per serving

Pau d'arco is a South American tree bark traditionally used for infections and inflammation, and it contains compounds like lapachol that show activit...

Pau d' Arco bark extract monograph & interactions

Other (inactive) ingredients: Water, Purified, Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

PauD'Arco Alcohol Free by Brainchild Nutritionals Drug Interactions

Want to check YOUR meds against PauD'Arco Alcohol Free?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
122Drugs
122 Moderate

Ingredients driving the most interactions

Pau d' Arco bark extract 122

Individual Drug Interactions

The ingredients in PauD'Arco Alcohol Free interact with 122 drugs. Click any drug to see the details.

1 of the 1 ingredient in PauD'Arco Alcohol Free interact with drugs. Each result below shows which ingredient is responsible. Pau d' Arco bark extract

Each ingredient & the kinds of drugs it affects

For each ingredient in PauD'Arco Alcohol Free with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Pau d' Arco bark extract1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, pau d'arco might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research shows that pau d'arco reduces platelet aggregation and may interfere with vitamin K. One clinical study shows that taking the lapachol constituent of pau d'arco in doses above 1.5 grams daily increases the risk of bleeding. The effects of whole pau d'arco or pau d'arco extract in humans are unclear.

Likelihood Possible Evidence D
Pau d' Arco bark extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for PauD'Arco Alcohol Free, from the product label.

Brainchild Nutritionals

See all Brainchild Nutritionals products
Name
Brainchild Nutritionals
City
Miami
State
FL
ZipCode
33179
Phone Number
(305) 952-3227
Web Address
brainchildnutritionals.com
Pharmacist Counseling Corner

PauD'Arco Alcohol Free by Brainchild Nutritionals: Common Questions

Does PauD'Arco Alcohol Free by Brainchild Nutritionals interact with any medications?
Yes. Based on its ingredients, PauD'Arco Alcohol Free has a known interaction with 122 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
PauD'Arco Alcohol Free contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant?
No. The safety data advises against pau d'arco during pregnancy because of possible harm to your developing baby and lack of solid safety information. Talk with your doctor about alternatives.
Is it safe to breastfeed while taking this?
No. There isn't enough safety data to know whether pau d'arco passes into breast milk or how it might affect a nursing infant, so it's best to avoid it while breastfeeding.
What's in this liquid besides the pau d'arco?
Just water, purified water, and glycerin. No alcohol, despite the name — that's what 'alcohol free' means. Those other ingredients are just there to keep it stable.
Does pau d'arco actually work for cancer, ulcers, or wound healing?
We don't have reliable evidence that it does. Our data rates all of those uses as 'insufficient evidence' — meaning the research so far doesn't clearly show it works. Don't rely on it as a main treatment for any of those conditions without talking to your doctor.
What side effects should I watch for?
At high doses — above 1.5 grams daily of its active lapachol — pau d'arco may cause nausea, vomiting, diarrhea, anemia, and bleeding problems. Human safety data is limited overall, so watch yourself closely and report any unusual symptoms to your pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if PauD'Arco Alcohol Free is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

PauD'Arco Alcohol Free label
Go deeper

The Full Monographs Behind PauD'Arco Alcohol Free’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Pau D'arco

Interacts with 122 drugs

Pau d'arco is a South American tree bark traditionally used for infections and inflammation, and it contains compounds like lapachol that show activity in lab studies. However, strong human...

Read the full Pau D'arco monograph →
Sources

Sources & How We Checked

PauD'Arco Alcohol Free's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Pau D'arco 6 references
  1. Gómez Castellanos JR, Prieto JM, Heinrich M. Red Lapacho (Tabebuia impetiginosa)--a global ethnopharmacological commodity? J Ethnopharmacol 2009;121:1-13. PubMed
  2. Guerra, Mde O., Mazoni, A. S., Brandao, M. A., and Peters, V. M. Toxicology of Lapachol in rats: embryolethality. Braz.J Biol. 2001;61(1):171-174. PubMed
  3. Felicio, A. C., Chang, C. V., Brandao, M. A., Peters, V. M., and Guerra, Mde O. Fetal growth in rats treated with lapachol. Contraception 2002;66(4):289-293. PubMed
  4. Son, D. J., Lim, Y., Park, Y. H., Chang, S. K., Yun, Y. P., Hong, J. T., Takeoka, G. R., Lee, K. G., Lee, S. E., Kim, M. R., Kim, J. H., and Park, B. S. Inhibitory effects of Tabebuia impetiginosa inner bark extract on platelet aggregation and vascular s
  5. Block JB, Serpick AA, Miller W, Wiernik PH. Early clinical studies with lapachol (NSC-11905). Cancer Chemother Rep 2. 1974;4(4):27-8.
  6. Algranti E, Mendonça EM, Ali SA, Kokron CM, Raile V. Occupational asthma caused by Ipe (Tabebuia spp) dust. J Investig Allergol Clin Immunol 2005;15(1):81-3.

See these in context on the Pau D'arco monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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