PEA with PQQ Ingredients & Drug Interactions
What is this page for?
First and foremost: checking PEA with PQQ against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
PEA with PQQ is a dietary supplement by Lake Avenue Nutrition with 2 active ingredients. Its ingredients are commonly taken for chronic pain, nerve (neuropathic) pain, inflammation.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of PEA with PQQ by Lake Avenue Nutrition
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
PEA with PQQ contains two active ingredients. Palmitoylethanolamide (PEA) is a fatty acid compound, and pyrroloquinoline quinone disodium salt (PQQ) is a coenzyme-like nutrient.
The remaining ingredients are inactive — fillers, binders, and capsule materials including modified cellulose, modified starch, rice husk, rice extract, gum Arabic, sunflower oil, and silicon dioxide.
Does it work?
Moderate evidence
Palmitoylethanolamide shows possibly effective evidence for osteoarthritis. For spinal cord injury, the evidence rates it as possibly ineffective.
For cannabis use disorder, autism spectrum disorder, carpal tunnel syndrome, and migraine headache, the evidence is too limited to rate. We hold no effectiveness data for pyrroloquinoline quinone disodium salt.
How safe is it?
Well-documented data
Palmitoylethanolamide is generally well tolerated in studies, though long-term safety data are limited. The most common side effect reported orally is nausea, which appears rarely and is mild and temporary.
The safety data advises against use during pregnancy and while breastfeeding due to insufficient information. We hold no safety data for pyrroloquinoline quinone disodium salt.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredients we could check. That said, we were unable to check pyrroloquinoline quinone disodium salt, so run your medications through the checker on this page before you start, and clear it with your doctor or pharmacist.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
If you're considering this product for osteoarthritis, the evidence for palmitoylethanolamide is modest but promising. PEA is generally well tolerated, though nausea is possible.
You'll want to avoid it if you're pregnant or breastfeeding. Talk with your doctor or pharmacist before starting — they can tell you whether it fits your situation.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about PEA with PQQ, straight from the product label.
| Brand | Lake Avenue Nutrition |
|---|---|
| Barcode (UPC) | 898220015917 |
| Net contents | 30 Veggie Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Nov 22, 2023 |
| DSLD ID | 299370 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), No Allergies, Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for PEA with PQQ by Lake Avenue Nutrition, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Palmitoylethanolamide | 600 mg | -- |
| Pyrroloquinoline Quinone Disodium Salt | 20 mg | -- |
Other ingredients: Modified Cellulose, Starch, Modified, Rice Husk, Rice extract, Gum Arabic, Sunflower Oil, Silicon Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested Use: Take 2 capsules daily with food, or as recommended by a Healthcare Practitioner.
Formulation
Formulated Without: GMOs, Gluten or Soy.
Supports Mitochondrial functional & joint comfort
Not manufactured with milk, eggs, fish, tree nuts, peanuts, wheat, soy, sesame, or gluten.
Precautions
Warnings: Keep out of reach of children.
As with all dietary supplements, it is recommended to consult with a healthcare professional before adding something new to your health and wellness regimen. Sealed for your protection. Do not use if seal is missing or broken.
Not manufactured with milk, eggs, fish, tree nuts, peanuts, wheat, soy, sesame, or gluten. Produced in a third-party, audited and registered cGMP compliant facility that may process other products that contain these allergens or ingredients.
Storage
Store in a cool, dry place.
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Formula
Palmitoylethanolamide & Pyrroloquinoline quinone
FDA Statement of Identity
Dietary Supplement
Brand IP Statement(s)
Lake Avenue Nutrition is a registered trademark of Madre Labs, LLC
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
PEA with PQQ by Lake Avenue Nutrition label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in PEA with PQQ by Lake Avenue Nutrition
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container15 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Palmitoylethanolamide
No knowninteractions
Palmitoylethanolamide (PEA) is a fat-like molecule made naturally in the body and studied mainly for pain and inflammation. Some research suggests it...
Palmitoylethanolamide monograph & interactionsPyrroloquinoline Quinone Disodium Salt
Other (inactive) ingredients: Modified Cellulose, Starch, Modified, Rice Husk, Rice extract, Gum Arabic, Sunflower Oil, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.
PEA with PQQ by Lake Avenue Nutrition Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in PEA with PQQ. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for PEA with PQQ, from the product label.
Lake Avenue Nutrition
See all Lake Avenue Nutrition products- Name
- Madre Labs, LLC
- Street Address
- 301 N. Lake Ave., Ste. 500
- City
- Pasadena
- State
- CA
- ZipCode
- 91101
- Web Address
- lakeavenuenutrition.com
PEA with PQQ by Lake Avenue Nutrition: Common Questions
Does PEA with PQQ by Lake Avenue Nutrition interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this while pregnant or breastfeeding?
What is PEA used for?
What's PQQ, and does it do anything?
What side effects might I have?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if PEA with PQQ is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind PEA with PQQ’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
PEA with PQQ's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 4 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Palmitoylethanolamide (pea) 4 references
- Indraccolo U, Barbieri F. Effect of palmitoylethanolamide-polydatin combination on chronic pelvic pain associated with endometriosis: preliminary observations. Eur J Obstet Gynecol Reprod Biol. 2010 May;150(1):76-9. PubMed
- Murina F, Graziottin A, Felice R, Radici G, Tognocchi C. Vestibulodynia: synergy between palmitoylethanolamide + transpolydatin and transcutaneous electrical nerve stimulation. J Low Genit Tract Dis. 2013 Apr;17(2):111-6.
- Papetti L, Sforza G, Tullo G, et al. Tolerability of palmitoylethanolamide in a pediatric population suffering from migraine: A pilot study. Pain Res Manag 2020;2020:3938640. PubMed
- Visse K, Blome C, Phan NQ, Augustin M, Ständer S. Efficacy of body lotion containing N-palmitoylethanolamine in subjects with chronic pruritus due to dry skin: A dermatocosmetic study. Acta Derm Venereol. 2017;97(5):639-641. PubMed
See these in context on the Palmitoylethanolamide (pea) monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC