No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

PhosChol Ingredients & Drug Interactions

by Nutrasal

PhosChol label
See full label image
Capsule Category: Fat/fatty Acid
No known interaction
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking PhosChol against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line No known interaction

PhosChol is a dietary supplement by Nutrasal with 1 active ingredient. Its ingredients are commonly taken for liver health, memory and brain support, ulcerative colitis.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

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HelloPharmacist Scorecard of PhosChol by Nutrasal

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

PhosChol has three active ingredients: phosphatidylcholine, polyunsaturated fat, and monounsaturated fat. Phosphatidylcholine is a compound found in cell membranes that has been studied for conditions like ulcerative colitis and fatty liver disease.

The product also contains safflower oil, neutral spirits, and cellulose as inactive ingredients.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Phosphatidylcholine's overall clinical evidence instead.

Moderate

Some clinical evidence supports Phosphatidylcholine for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Ulcerative colitis — rated "Possibly Effective" (Natural Medicines).

Phosphatidylcholine is possibly effective for ulcerative colitis. For nonalcoholic fatty liver disease, alcohol-related liver disease, Alzheimer disease, and anxiety, the evidence is insufficient to know whether it works.

We hold no effectiveness data for the polyunsaturated fat and monounsaturated fat in this product.

The evidence, ingredient by ingredient Phosphatidylcholine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Phosphatidylcholine is generally well tolerated when taken by mouth. The most common side effects are altered taste, bloating, diarrhea, itching, nausea, sweating, and vomiting—especially at higher doses.

Large doses (30 grams per day) can cause digestive upset and diarrhea; even smaller doses have caused bloating, diarrhea, nausea, and vomiting in some people. Choline is needed in pregnancy, but the safety of phosphatidylcholine supplements beyond what's in food is not well studied—check with your doctor.

There isn't enough reliable data on supplement use while breastfeeding; speak with your healthcare provider first.

Side effects, ingredient by ingredient Phosphatidylcholine

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the phosphatidylcholine we checked. Because we hold no interaction data for polyunsaturated fat and monounsaturated fat, check your exact medications with the tool on this page before you start, or ask your pharmacist.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.

PhosChol may be worth considering if you have ulcerative colitis and want to explore what the research shows as possibly effective. If you're pregnant, breastfeeding, or take any medications, talk with your doctor or pharmacist before you start.

They can help you figure out whether it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about PhosChol, straight from the product label.

Brand Nutrasal
Barcode (UPC) 013964121056
Net contents 120 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Feb 23, 2022
DSLD ID 261274
Product type Fat/fatty Acid
Supplement form Capsule
Dietary claims / uses Nutrient, All Other
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for PhosChol by Nutrasal, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Vegetarian Capsule(s)
Maximum serving Sizes:
4 Vegetarian Capsule(s)
Servings per container
30
UPC/BARCODE
013964121056
IngredientAmount% DV
Calories20 Calorie(s)--
Calories from Fat20 Calorie(s)--
Polyunsaturated Fat0.5 Gram(s)--
Total Fat2 Gram(s)3%
Saturated Fat0 Gram(s)--
Monounsaturated Fat1.5 Gram(s)--
Phosphatidylcholine2400 mg--

Other ingredients: Safflower Oil, neutral Spirits, Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Each Serving Provides: 2.4 grams of pharmaceutical grade Polyenylphosphatidylcholine (PPC).

(100% polyenylphosphatidylcholine) PPC Polyenylphosphatidylcholine

Suggested/Recommended/Usage/Directions

Suggested Usage: As a dietary supplement, take 3-4 capsules per day, or as directed by your health care practitioner.

Storage

Storage: Keep tightly closed in a cool dry place, out of the reach of children.

Precautions

Do not take if tamper resistant seal is broken or missing.

Formulation

This product is pharmaceutical grade and intended for professional use. It is manufactured under strict quality controls to ensure purity, potency and reliability.

Pharmaceutical grade

Contains No: Wheat, gluten, corn, soy protein, yeast, dairy products, artificial colors, sweeteners, or preservatives.

Brand IP Statement(s)

Nutrasal Advanced Lipid Science

Seals/Symbols

Made in USA cGMP Compliant

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

PhosChol by Nutrasal label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

PhosChol label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in PhosChol by Nutrasal

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size3 Vegetarian Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Phosphatidylcholine

No known
interactions
2400 mg per serving Form: Polyenylphosphatidylcholine, Soy

Phosphatidylcholine is a phospholipid that is part of every cell membrane and a source of choline. People take it for liver, brain, and gut health, bu...

Phosphatidylcholine monograph & interactions

Other (inactive) ingredients: Safflower Oil, Neutral Spirits, Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

PhosChol by Nutrasal Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in PhosChol. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for PhosChol, from the product label.

Nutrasal

See all Nutrasal products
Name
Nutrasal, Inc.
City
Scottsdale
State
AZ
Phone Number
800.777.1886
Web Address
nutrasal.com
Pharmacist Counseling Corner

PhosChol by Nutrasal: Common Questions

Does PhosChol by Nutrasal interact with any medications?
We do not currently list a known interaction for the mapped ingredients in PhosChol. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
PhosChol contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take PhosChol while I'm pregnant?
Choline is a nutrient you need during pregnancy, but we don't have enough reliable data on the safety of phosphatidylcholine supplements beyond food sources during pregnancy. Talk with your doctor before you take it so they can give you personalized advice.
Can I take PhosChol while breastfeeding?
We don't have enough reliable data on PhosChol's safety during breastfeeding. Speak with your healthcare provider first to make sure it's okay for you and your baby.
What are the side effects?
The most common side effects from taking it by mouth are altered taste, bloating, diarrhea, itching, nausea, sweating, and vomiting. High doses (30 grams a day) are more likely to cause digestive upset, but these side effects have been reported even at smaller doses in some people.
Will PhosChol help with my fatty liver?
Phosphatidylcholine has been studied for nonalcoholic fatty liver disease and alcohol-related liver disease, but the evidence is insufficient to say whether it works. If you have liver disease, talk with your doctor about whether to try it and how it fits into your care.
What is phosphatidylcholine?
Phosphatidylcholine is a compound found naturally in cell membranes. It's studied for conditions like ulcerative colitis (where there's some evidence it may help) and fatty liver disease (where the evidence isn't yet clear).

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if PhosChol is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

PhosChol label
Go deeper

The Full Monographs Behind PhosChol’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Phosphatidylcholine

Phosphatidylcholine is a phospholipid that is part of every cell membrane and a source of choline. People take it for liver, brain, and gut health, but solid human evidence is limited for mo...

Read the full Phosphatidylcholine monograph →
Sources

Sources & How We Checked

PhosChol's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Phosphatidylcholine 15 references
  1. Domino EF, May WW, Demetriou S, et al. Lack of clinically significant improvement of patients with tardive dyskinesia following phosphatidylcholine therapy. Biol Psychiatry 1985;20:1189-96. PubMed
  2. Aronson PJ, Lorincz AL. Promotion of palmar sweating with oral phosphatidylcholine. Acta Derm Venereol 1985;65:19-24. DOI
  3. Hexsel DM, Serra M, de Oliveira Dal'Forno T, et al. Cosmetic uses of injectable phosphatidylcholine on the face. Otolaryngol Clin North Am 2005;38:1119-29. PubMed
  4. Kopera D, Binder B, Toplak H, et al. Histopathologic changes after intralesional application of phosphatidylcholine for lipoma reduction: report of a case. Am J Dermatopathol 2006;28:331-3. PubMed
  5. Rittes PG. The use of phosphatidylcholine for correction of lower lid bulging due to prominent fat pads. Dermatol Surg 2001;27:391-2. PubMed
  6. Rotunda AM, Kolodney MS. Mesotherapy and phosphatidylcholine injections: historical clarification and review. Dermatol Surg 2006;32:465-80. PubMed
  7. Hexsel D, Serra M, Mazzuco R, et al. Phosphatidylcholine in the treatment of localized fat. J Drugs Dermatol 2003;2:511-8.
  8. Hasengschwandtner F. Phosphatidylcholine treatment to induce lipolysis. Cosmet Dermatol 2005;4:308-13. PubMed
  9. Rittes PG. The use of phosphatidylcholine for correction of localized fat deposits. Aesthetic Plast Surg 2003;27:315-8. PubMed
  10. Ablon G, Rotunda AM. Treatment of lower eyelid fat pads using phosphatidylcholine: clinical trial and review. Dermatol Surg 2004;30:422-7. PubMed
  11. Loguercio C, Andreone P, Brisc C, et al. Silybin combined with phosphatidylcholine and vitamin E in patients with nonalcoholic fatty liver disease: a randomized controlled trial. Free Radic Biol Med 2012;52(9):1658-65. PubMed
  12. Panos, J. M., Palson, R., Johnson, R., Portmann, B., and Williams, R. Polyunsaturated phosphatidylcholine for acute alcoholic hepatitis: a double blind randomized placebo controlled trial. Eur.J.Gastroenterol 1990;2:351-355.
  13. Stremmel W, Braun A, Hanemann A, Ehehalt R, Autschbach F, Karner M. Delayed release phosphatidylcholine in chronic-active ulcerative colitis: a randomized, double-blinded, dose finding study. J Clin Gastroenterol 2010;44(5):e101-7. PubMed
  14. Stremmel W, Ehehalt R, Autschbach F, Karner M. Phosphatidylcholine for steroid-refractory chronic ulcerative colitis: a randomized trial. Ann Intern Med. 2007;147(9):603-10. PubMed
  15. Stremmel W, Vural H, Evliyaoglu O, Weiskirchen R. Delayed Release Phosphatidylcholine is Effective for Treatment of Ulcerative Colitis: A Meta-Analysis. Dig Dis 2021;39(5):508-515. PubMed

See these in context on the Phosphatidylcholine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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