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Dietary supplement

Phosphatidyl Choline Complex 1200 mg Ingredients & Drug Interactions

by Country Life

Softgel Capsule Category: Fat/fatty Acid
Most serious interaction: Minor
The interaction bottom line Most serious interaction: Minor

Phosphatidyl Choline Complex 1200 mg is a dietary supplement by Country Life with 2 active ingredients. Its ingredients are commonly taken for liver health, memory and brain support, ulcerative colitis.Based on those ingredients, 16 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Choline. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Phosphatidyl Choline Complex 1200 mg by Country Life

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • “Phosphatidyl Choline Complex” is a proprietary blend — the label gives one combined amount (1,200 mg) without saying how much of each component you get.

This product contains 2 active ingredients: phosphatidylcholine and choline. Phosphatidylcholine is a naturally occurring compound found in cell membranes and is present in many foods.

Choline is an essential nutrient your body uses for nerve and brain function and is also found in foods like eggs and fish. The remaining ingredients (gelatin, glycerin, purified water, and soybean oil) are inactive — they make up the softgel capsule and don't provide therapeutic action.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: Brain health and memory support.
  • We looked for evidence on: Age-related cognitive decline, Alzheimer disease, Cognitive function, Dementia, Memory, Neurotransmitter function — and 1 related terms.
  • The closest evidence on file: Choline is rated "Insufficient Reliable Evidence To Rate" for Age-related cognitive decline (Natural Medicines).
  • Also on file: Choline is rated "Insufficient Reliable Evidence To Rate" for Alzheimer disease, Cognitive function, Dementia.
  • Also on file: Phosphatidylcholine is rated "Insufficient Reliable Evidence To Rate" for Alzheimer disease, Memory, Dementia.

Phosphatidylcholine has possibly effective evidence for ulcerative colitis (inflammatory bowel disease), but the evidence for fatty liver disease, alcohol-related liver damage, Alzheimer disease, and anxiety isn't solid enough to rate. Choline shows possibly ineffective evidence for athletic performance.

For the other conditions in our data — bronchitis, age-related cognitive decline, fatty liver from nutritional support, and hay fever — we don't have established evidence on file. Talk with your doctor or pharmacist about whether this product is right for what you're hoping it'll do.

The evidence, ingredient by ingredient Phosphatidylcholine Choline

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Both ingredients are generally well tolerated at typical doses. At high doses, phosphatidylcholine can cause digestive upset (bloating, diarrhea, nausea, vomiting) and altered taste; large amounts of choline (9 grams daily or more) can cause a fishy body odor, diarrhea, nausea, vomiting, and sweating.

Choline is needed during pregnancy, but supplement safety beyond food sources isn't well studied — your doctor should advise on dosing. The same applies to breastfeeding: choline needs are higher while nursing, but use only under professional guidance.

If you're pregnant or breastfeeding, check with your healthcare provider before starting.

Side effects, ingredient by ingredient Phosphatidylcholine Choline

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Choline.
  • The most serious interaction on file is rated Minor.
  • For scale: 16 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

The choline in this product has a Minor interaction documented with atropine and related anticholinergic medications — it may decrease their effects. Because we have no interaction data on file for phosphatidylcholine, you should check your exact medications using the search tool on this page before starting.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Only minor medication interactions are documented, and safety information is well characterized.

Phosphatidyl Choline Complex may be worth considering if you're interested in supporting liver or digestive health, though evidence is limited for most uses. If you take atropine or any other prescription medication, check with your pharmacist first — choline can theoretically affect how atropine works.

Pregnancy and breastfeeding? Talk to your doctor before taking this.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 21, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Phosphatidyl Choline Complex 1200 mg, straight from the product label.

Brand Country Life
Barcode (UPC) 015794045533
Net contents 200 Softgel(s)
Market status On market
Date entered into DSLD May 21, 2025
DSLD ID 333216
Product type Fat/fatty Acid
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Phosphatidyl Choline Complex 1200 mg by Country Life, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
200
UPC/BARCODE
015794045533
IngredientAmount% DV
Calories10 Calorie(s)--
Total Fat1 Gram(s)2%
Phosphatidylcholine420 mg--
Phosphatidyl Choline Complex1200 mg--
Choline55 mg10%

Other ingredients: Gelatin, Glycerin, Water, Purified, Soybean Oil

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Phosphatidylcholine (PC) is a phospholipid present in all cell membranes throughout the body (and the brain in particular) and contains choline, an important precursor to acetylcholine, a neurotransmitter in the brain. Country Life provides our best selling Phosphatidyl Choline Complex that contains 420 mg of PC to helps support cell membranes, and support healthy cognitive function. Based on SPINSscan Natural 52 weeks ending 09/04/2022.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formulation

Yes Certified Gluten-free by GFCO.org No yeast, corn or wheat No milk, salt or sugar No preservatives No artificial colors, flavors No artificial sweeteners No magnesium stearate

Yes manufacturing supports wind power This product has been manufactured at a GMP registered facility.

Certified gluten-free

Promotes healthy cognitive function Helps support cell membranes Helps to process fats Our Pledge of Integrity Authenticity Cleanliness Freshness Consistency Accuracy

Made in the USA with globally sourced ingredients

General Statements

Yes recyclable packaging

Seals/Symbols

Certified Gluten Free GFCO.org Certified B Corporation

Brand IP Statement(s)

Country Life Established 1971

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Adults take one (1) softgel daily with food.

Precautions

As a reminder, discuss the supplements and medications that you take with your health care providers. Caution: If you are pregnant, nursing, or taking medication, have a medical condition or planning surgery, consult a doctor before using this product.

Contains soy.

Stop using and consult a doctor if any adverse reactions occur. Do not accept if seal is broken.

Keep out of the reach of children.

Storage

Store in a dry place between 59 degrees - 86 degrees F.

See for yourself

Phosphatidyl Choline Complex 1200 mg by Country Life label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Phosphatidyl Choline Complex 1200 mg by Country Life

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container200 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Phosphatidyl Choline Complex

No known
interactions
1200 mg per serving Form: Soy Lecithin

Phosphatidylcholine is a phospholipid that is part of every cell membrane and a source of choline. People take it for liver, brain, and gut health, bu...

Phosphatidyl Choline Complex monograph & interactions

Choline

Interacts with
16 drugs
55 mg per serving Form: Phosphatidylcholine

Choline is an essential nutrient your body needs for liver function, brain health, and nerve signaling, and many people get enough from foods like egg...

Choline monograph & interactions

Other (inactive) ingredients: Gelatin, Glycerin, Water, Purified, Soybean Oil. These complete the product’s ingredient list but are not active constituents.

Interaction report

Phosphatidyl Choline Complex 1200 mg by Country Life Drug Interactions

Want to check YOUR meds against Phosphatidyl Choline Complex 1200 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
16Drugs
16 Minor

Ingredients driving the most interactions

Choline 16

Each ingredient & the kinds of drugs it affects

For each ingredient in Phosphatidyl Choline Complex 1200 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Choline1 drug type · 16 drugs

Atropine

Theoretically, choline might decrease the effects of atropine in the brain.
Animal research shows that administering choline one hour before administering atropine can attenuate atropine-induced decreases in brain levels of acetylcholine. Theoretically, concomitant use of choline and atropine may decrease the effects of atropine.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Phosphatidyl Choline Complex 1200 mg, from the product label.

Country Life

See all Country Life products
Name
Country Life, LLC
Street Address
180 Vanderbilt Motor Parkway
City
Hauppauge
State
NY
ZipCode
11788
Web Address
CountryLifeVitamins.com
Pharmacist Counseling Corner

Phosphatidyl Choline Complex 1200 mg by Country Life: Common Questions

Does Phosphatidyl Choline Complex 1200 mg by Country Life interact with any medications?
Yes. Based on its ingredients, Phosphatidyl Choline Complex 1200 mg has a known interaction with 16 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Phosphatidyl Choline Complex 1200 mg contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What are phosphatidylcholine and choline used for in this product?
Phosphatidylcholine and choline are compounds your body naturally makes and uses for brain, nerve, and cell membrane function. This product is marketed for liver and cognitive support, though solid evidence exists mainly for phosphatidylcholine in ulcerative colitis.
Can this cause digestive side effects?
Yes, both ingredients can cause bloating, diarrhea, nausea, and vomiting — especially at higher doses. High-dose choline may also cause a fishy body odor. Most of these effects happen at doses well above what's in a typical dose of this product.
Is it safe to take while pregnant?
Choline is needed during pregnancy, but the safety of supplement doses beyond food sources isn't well studied. Your doctor should advise on whether supplementation is right for you and at what dose.
Can I take this while breastfeeding?
Choline needs are higher while breastfeeding, but there isn't enough reliable data on supplement safety during nursing. Talk with your healthcare provider before starting to make sure it's appropriate for you.
Does this product have fillers?
Yes — the softgel capsule contains gelatin, glycerin, purified water, and soybean oil as inactive ingredients. These don't provide therapeutic benefit but help make the capsule work.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Phosphatidyl Choline Complex 1200 mg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Phosphatidyl Choline Complex 1200 mg label
Sources

Sources & How We Checked

Phosphatidyl Choline Complex 1200 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 29 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Phosphatidylcholine 15 references
  1. Domino EF, May WW, Demetriou S, et al. Lack of clinically significant improvement of patients with tardive dyskinesia following phosphatidylcholine therapy. Biol Psychiatry 1985;20:1189-96. PubMed
  2. Aronson PJ, Lorincz AL. Promotion of palmar sweating with oral phosphatidylcholine. Acta Derm Venereol 1985;65:19-24. DOI
  3. Hexsel DM, Serra M, de Oliveira Dal'Forno T, et al. Cosmetic uses of injectable phosphatidylcholine on the face. Otolaryngol Clin North Am 2005;38:1119-29. PubMed
  4. Kopera D, Binder B, Toplak H, et al. Histopathologic changes after intralesional application of phosphatidylcholine for lipoma reduction: report of a case. Am J Dermatopathol 2006;28:331-3. PubMed
  5. Rittes PG. The use of phosphatidylcholine for correction of lower lid bulging due to prominent fat pads. Dermatol Surg 2001;27:391-2. PubMed
  6. Rotunda AM, Kolodney MS. Mesotherapy and phosphatidylcholine injections: historical clarification and review. Dermatol Surg 2006;32:465-80. PubMed
  7. Hexsel D, Serra M, Mazzuco R, et al. Phosphatidylcholine in the treatment of localized fat. J Drugs Dermatol 2003;2:511-8.
  8. Hasengschwandtner F. Phosphatidylcholine treatment to induce lipolysis. Cosmet Dermatol 2005;4:308-13. PubMed
  9. Rittes PG. The use of phosphatidylcholine for correction of localized fat deposits. Aesthetic Plast Surg 2003;27:315-8. PubMed
  10. Ablon G, Rotunda AM. Treatment of lower eyelid fat pads using phosphatidylcholine: clinical trial and review. Dermatol Surg 2004;30:422-7. PubMed
  11. Loguercio C, Andreone P, Brisc C, et al. Silybin combined with phosphatidylcholine and vitamin E in patients with nonalcoholic fatty liver disease: a randomized controlled trial. Free Radic Biol Med 2012;52(9):1658-65. PubMed
  12. Panos, J. M., Palson, R., Johnson, R., Portmann, B., and Williams, R. Polyunsaturated phosphatidylcholine for acute alcoholic hepatitis: a double blind randomized placebo controlled trial. Eur.J.Gastroenterol 1990;2:351-355.
  13. Stremmel W, Braun A, Hanemann A, Ehehalt R, Autschbach F, Karner M. Delayed release phosphatidylcholine in chronic-active ulcerative colitis: a randomized, double-blinded, dose finding study. J Clin Gastroenterol 2010;44(5):e101-7. PubMed
  14. Stremmel W, Ehehalt R, Autschbach F, Karner M. Phosphatidylcholine for steroid-refractory chronic ulcerative colitis: a randomized trial. Ann Intern Med. 2007;147(9):603-10. PubMed
  15. Stremmel W, Vural H, Evliyaoglu O, Weiskirchen R. Delayed Release Phosphatidylcholine is Effective for Treatment of Ulcerative Colitis: A Meta-Analysis. Dig Dis 2021;39(5):508-515. PubMed

See these in context on the Phosphatidylcholine monograph →

Choline 14 references
  1. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  2. Cho E, Willett WC, Colditz GA, et al. Dietary choline and betaine and the risk of distal colorectal adenoma in women. J Natl Cancer Inst 2007;99:1224-31. PubMed
  3. Schmidt, C., Abicht, A., Krampfl, K., Voss, W., Stucka, R., Mildner, G., Petrova, S., Schara, U., Mortier, W., Bufler, J., Huebner, A., and Lochmuller, H. Congenital myasthenic syndrome due to a novel missense mutation in the gene encoding choline acetyl
  4. Tamminga, C., Smith, R. C., Chang, S., Haraszti, J. S., and Davis, J. M. Depression associated with oral choline. Lancet 10-23-1976;2(7991):905. PubMed
  5. Wood, J. L. and Allison, R. G. Effects of consumption of choline and lecithin on neurological and cardiovascular systems. Fed.Proc. 1982;41(14):3015-3021.
  6. Growdon, J. H. and Gelenberg, A. J. Choline and lecithin administration to patients with tardive dyskinesia. Trans.Am.Neurol.Assoc. 1978;103:95-99.
  7. Smith, C. M., Swash, M., Exton-Smith, A. N., Phillips, M. J., Overstall, P. W., Piper, M. E., and Bailey, M. R. Choline therapy in Alzheimer's disease. Lancet 8-5-1978;2(8084):318. PubMed
  8. Morrison, L. M. and W. F. Gonzales. Choline in coronary atherosclerosis. Amer.Heart J. 1950;39:729.
  9. Christie, J. G. Blackburn 1. M. Glen A. I. M. Zeisel S. Shering A. & Yates C. M. Effects of choline and lecithin on CSF choline levels and on cognitive functioning in patients with presenile dementia of the Alzheimer type. Nutrition and the brain 1979;5
  10. Sidhu N, Davies S, Nadarajah A, et al. Oral choline supplementation for postoperative pain. Br J Anaesth 2013;111(2):249-55. PubMed
  11. Wozniak JR, Fuglestad AJ, Eckerle JK, et al. Choline supplementation in children with fetal alcohol spectrum disorders has high feasibility and tolerability. Nutr Res. 2013;33(11):897-904. PubMed
  12. Wozniak JR, Fuglestad AJ, Eckerle JK, et al. Choline supplementation in children with fetal alcohol disorders: a randomized, double-blind, placebo-controlled trial. Am J Clin Nutr. 2015;102(5): 1113-25.
  13. Ross RG, Hunter SK, McCarthy L, et al. Perinatal choline effects on neonatal pathophysiology related to later schizophrenia risk. Am J Psychiatry. 2013;170(3):290-8. PubMed
  14. Food and Nutrition Board, Institute of Medicine. Choline. Dietary Reference Intakes: Thiamin, Riboflavin, Niacin, Vitamin B-6, Vitamin B-12, Pantothenic Acid, Biotin, and Choline. Washington D.C.: National Academy Press; 1998:390-422.

See these in context on the Choline monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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