No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Pipsissewa Ingredients & Drug Interactions

by Herbal Terra

Liquid Category: Botanical
No known interaction
The interaction bottom line No known interaction

Pipsissewa is a dietary supplement by Herbal Terra with 1 active ingredient. Its ingredients are commonly taken for urinary tract support, diuretic (increasing urine flow), mild inflammation.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Pipsissewa by Herbal Terra

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: wildcrafted Pipsissewa extract, a plant preparation used traditionally for a range of conditions. The liquid also includes Menstruum, a solvent used to extract and preserve the herb.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Pipsissewa product and its label doesn't state a use — see Pipsissewa's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence supporting Pipsissewa for cancer, diabetes, epilepsy, kidney stones, or urinary tract infections is insufficient — we don't have reliable data showing whether it works for any of these uses. If you're considering it for a specific health concern, talk with your doctor or pharmacist about what the science actually shows and what other options might be better established.

The evidence, ingredient by ingredient Pipsissewa

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Long traditional use exists, but modern safety and effectiveness data are limited. The main concern is hydroquinone toxicity from chronic oral use — a compound naturally present in pipsissewa that can build up and cause vomiting, delirium, convulsions, or collapse with prolonged use.

The safety data advises against use during pregnancy and while breastfeeding.

Side effects, ingredient by ingredient Pipsissewa

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the medications we could check. However, before you combine this with any prescription or over-the-counter drug, confirm with your own doctor or pharmacist, since interaction data for herbal products can be incomplete.

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Pipsissewa has a long history in traditional medicine, but solid modern evidence for its safety and effectiveness is lacking. If you're pregnant, breastfeeding, or considering this for a specific condition, talk it over with your doctor or pharmacist before you start — they can help you weigh the limited data and explore other options that might be better supported.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pipsissewa, straight from the product label.

Brand Herbal Terra
Barcode (UPC) 7429524233276
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Sep 25, 2020
DSLD ID 234117
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pipsissewa by Herbal Terra, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1 mL
Servings per container
120
UPC/BARCODE
7429524233276
IngredientAmount% DV
wildcrafted Pipsissewa extract970 mg--

Other ingredients: Menstruum

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Direction Shake well before use. Adults take up to 30 drops (1 mL, one full squeeze of the dropper bulb) in 3-4 fl. oz of juice or water up to 4 times a day. We recommend to seek expert medical advice before taking this or any other herbal supplements.

FDA Disclaimer Statement

Notice This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

Manufactured in the USA in an FDA registered facility

Sugar free

Dried herb/menstruum ratio: 1:3 Expertly extracted Laboratory tested 330 mg/1 mL Premium product Super concentrated liquid herbal extract

Non GMO

No artificial ingredients, GMO, gluten, color additives, fillers, preservatives or binders. Natural Gluten Free

Origin of plant material: USA.

Precautions

Caution May have contraindications.

Do not use if you are allergic to any ingredients.

Consult a physician before using during pregnancy, if nursing, or if you are on any medications.

Keep out of the reach of children.

Storage

Store in a cool, dry, dark place.

Formula

Chimaphila umbellata

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

Made in USA Made in an FDA registered facility Natural Gluten Free

See for yourself

Pipsissewa by Herbal Terra label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Pipsissewa by Herbal Terra

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.

Wildcrafted Pipsissewa extract

No known
interactions
970 mg per serving

Pipsissewa is a North American forest herb with a long history of traditional use as a diuretic and urinary remedy, but modern human research is very...

Wildcrafted Pipsissewa extract monograph & interactions

Other (inactive) ingredients: Menstruum. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pipsissewa by Herbal Terra Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Pipsissewa. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Pipsissewa, from the product label.

Herbal Terra

See all Herbal Terra products
Name
Herbal Terra
Pharmacist Counseling Corner

Pipsissewa by Herbal Terra: Common Questions

Does Pipsissewa by Herbal Terra interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Pipsissewa. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Pipsissewa contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is Pipsissewa safe to use while I'm pregnant?
The safety data advises against use during pregnancy. There isn't enough information to know it's safe, so it's best to avoid it and talk with your doctor or pharmacist about what's right for you during pregnancy.
Can I take this while breastfeeding?
No reliable safety information is available, so the data advises against use while breastfeeding. Talk with your doctor or pharmacist about whether this product is right for you.
Does Pipsissewa really work for urinary tract infections?
The evidence is insufficient — we don't have reliable data showing whether it works. If you're dealing with a UTI, your doctor or pharmacist can recommend treatments that have stronger evidence behind them.
What are the side effects I should watch for?
Chronic use may lead to hydroquinone toxicity (a buildup of a natural compound in the herb), which could cause vomiting, delirium, convulsions, or collapse. Modern safety data are limited, so talk with your pharmacist or doctor if you're using this long-term or experience any unusual symptoms.
Why is the safety data so limited?
Pipsissewa has a long traditional history, but modern scientific studies on its safety and effectiveness are scarce. That's why the data we have are mostly cautions rather than clear answers.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pipsissewa is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pipsissewa label
Go deeper

The Full Monographs Behind Pipsissewa’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Pipsissewa's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Pipsissewa 2 references
  1. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

See these in context on the Pipsissewa monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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