Saw Palmetto Compound Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Saw Palmetto Compound against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Saw Palmetto Compound is a dietary supplement by Wise Woman Herbals with 4 active ingredients. Its ingredients are commonly taken for benign prostatic hyperplasia (bph) symptoms, urinary problems, hair loss.Based on those ingredients, 336 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Saw Palmetto, Stinging Nettle. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Saw Palmetto Compound by Wise Woman Herbals
Ask about any prescription or over-the-counter medication and we check it for interactions with Saw Palmetto Compound by Wise Woman Herbals — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Saw Palmetto Compound by Wise Woman Herbals
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
This liquid blend contains four active ingredients. Saw palmetto is traditionally used for prostate and urinary symptoms.
Stinging nettle leaf and root are included for their potential effects on blood sugar and inflammation. Cleavers and pipsissewa round out the formula, though we hold limited modern data on cleavers' effects.
The liquid is preserved with alcohol and glycerin and mixed with spring water.
Does it work?
Moderate evidence
The evidence for this blend is mixed. Saw palmetto is possibly ineffective for benign prostate enlargement (BPH) — the most common reason people use it — though it's possibly effective for symptoms after prostate surgery (TURP).
Stinging nettle is possibly effective for diabetes, but most of its other traditional uses lack reliable evidence. For pipsissewa and cleavers, modern effectiveness data isn't established in the information we hold.
How safe is it?
Well-documented data
Saw palmetto and stinging nettle are generally well tolerated when used as directed, though mild side effects like nausea, diarrhea, dizziness, and abdominal pain occur occasionally with saw palmetto. Stinging nettle's most common oral side effects are constipation or diarrhea.
Both are contraindicated in pregnancy and breastfeeding due to hormonal effects and insufficient safety data. Pipsissewa, used long traditionally, carries a caution: chronic oral use may lead to hydroquinone toxicity, with symptoms including vomiting, delirium, convulsions, and collapse.
Avoid it in pregnancy and breastfeeding. A rare case of liver injury has been reported with herbal blends containing stinging nettle.
Meds to double-check
Moderate interaction found
Before taking this product, check with your own doctor or pharmacist if you use blood thinners or antiplatelet drugs (saw palmetto and stinging nettle both affect bleeding), birth control or hormone therapy (saw palmetto may reduce their effectiveness), diabetes medications (stinging nettle may lower blood sugar further), lithium (stinging nettle may raise levels), diuretics or water pills (stinging nettle may enhance their effect), or warfarin (stinging nettle's vitamin K may interfere). These are the medication types most likely to be affected.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
This product is marketed for prostate and urinary health, but the evidence for saw palmetto's effectiveness in that area is weak. It's best suited for people without blood clotting disorders, hormonal sensitivities, or diabetes who aren't on lithium, diuretics, or warfarin.
Before you start, discuss it with your doctor or pharmacist — especially if you take any blood thinners, birth control, diabetes medications, or heart drugs.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 21, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Saw Palmetto Compound, straight from the product label.
| Brand | Wise Woman Herbals |
|---|---|
| Barcode (UPC) | 748840003231 |
| Net contents | 2 Fluid Ounce(s); 60 mL |
| Market status | On market |
| Date entered into DSLD | Feb 21, 2023 |
| DSLD ID | 284919 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Saw Palmetto Compound by Wise Woman Herbals, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Blend | 3 mL | -- |
| Saw Palmetto | 0 NP | -- |
| Stinging Nettle | 0 NP | -- |
| Cleavers | 0 NP | -- |
| Pipsissewa | 0 NP | -- |
Other ingredients: Alcohol, Spring Water, Glycerin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested Use: Add 20-60 drops to water, 1-4 times per day.
Formulation
The presence of particulate matter in this product is normal.
Precautions
Caution: Keep out of the reach of children.
General Statements
Botanical formula
FDA Statement of Identity
Dietary Supplement
Storage
Store in a cool, dry area away from direct sunlight with the lid tightly sealed.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Saw Palmetto Compound by Wise Woman Herbals label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Saw Palmetto Compound by Wise Woman Herbals
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size20 Drop(s) Dosage formLiquid Servings per container20 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Blend
- › Saw Palmetto
- › Stinging Nettle
- › Cleavers
- › Pipsissewa
Other (inactive) ingredients: Alcohol, Spring Water, Glycerin. These complete the product’s ingredient list but are not active constituents.
Saw Palmetto Compound by Wise Woman Herbals Drug Interactions
HelloPharmacist Interaction Report
Saw Palmetto Compound by Wise Woman Herbals contains ingredients with documented interactions: saw palmetto, stinging nettle, and pipsissewa.
The most serious interaction is saw palmetto with blood thinners (anticoagulants) and antiplatelet drugs — saw palmetto may prolong bleeding time and raise the risk of bleeding when combined with these medications.
Read the full breakdown — every affected drug type, severity by severity
Saw palmetto also interacts with hormonal medications. It may reduce the effectiveness of estrogens and birth control drugs through antiestrogenic effects.
Stinging nettle has its own set of interactions: it may lower blood sugar additively with diabetes medications, has diuretic effects that could combine with water pills, may interfere with warfarin (a common blood thinner) because of its vitamin K content, and theoretically could raise lithium levels by reducing its excretion.
We could not check cleavers — no data is on file for it. Pipsissewa, which we reviewed, has no interactions documented in our data.
Altogether, these interactions span 336 individual medications. Use the search tool below to check your exact medications before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Saw Palmetto Compound?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Saw Palmetto Compound interact with 336 drugs. Click any drug to see the details.
2 of the 4 ingredients in Saw Palmetto Compound interact with drugs. Each result below shows which ingredient is responsible. Saw Palmetto Stinging Nettle
AbciximabReoPro
How Abciximab interacts with Saw Palmetto Compound — through 1 ingredient. Tap an ingredient for the detail:
Saw PalmettoAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Saw Palmetto Compound — through 1 ingredient. Tap an ingredient for the detail:
Saw PalmettoAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Saw Palmetto Compound — through 1 ingredient. Tap an ingredient for the detail:
Stinging NettleAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Read the full Stinging Nettle + Acarbose interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Saw Palmetto Compound — through 1 ingredient. Tap an ingredient for the detail:
Saw PalmettoAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Saw Palmetto Compound — through 1 ingredient. Tap an ingredient for the detail:
Saw PalmettoAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Saw Palmetto Compound — through 1 ingredient. Tap an ingredient for the detail:
Saw PalmettoAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Saw Palmetto Compound — through 1 ingredient. Tap an ingredient for the detail:
Stinging NettleDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Stinging Nettle + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Saw Palmetto Compound — through 1 ingredient. Tap an ingredient for the detail:
Saw PalmettoAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto + Acetaminophen, Ibuprofen interactionAcetaminophen, Pamabrom, PyrilamineMidol Max Strength PMS, Pamprin, Pamprin ES
How Acetaminophen, Pamabrom, Pyrilamine interacts with Saw Palmetto Compound — through 1 ingredient. Tap an ingredient for the detail:
Stinging NettleDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Stinging Nettle + Acetaminophen, Pamabrom, Pyrilamine interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Saw Palmetto Compound — through 1 ingredient. Tap an ingredient for the detail:
Stinging NettleDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Stinging Nettle + Acetazolamide interactionAcetohexamideDymelor
How Acetohexamide interacts with Saw Palmetto Compound — through 1 ingredient. Tap an ingredient for the detail:
Stinging NettleAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Read the full Stinging Nettle + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Saw Palmetto Compound — through 1 ingredient. Tap an ingredient for the detail:
Saw PalmettoAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto + Acetylsalicylic Acid interactionAlbiglutideTanzeum
How Albiglutide interacts with Saw Palmetto Compound — through 1 ingredient. Tap an ingredient for the detail:
Stinging NettleAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Read the full Stinging Nettle + Albiglutide interactionAlogliptinNesina
How Alogliptin interacts with Saw Palmetto Compound — through 1 ingredient. Tap an ingredient for the detail:
Stinging NettleAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Read the full Stinging Nettle + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Saw Palmetto Compound — through 1 ingredient. Tap an ingredient for the detail:
Stinging NettleAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Read the full Stinging Nettle + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Saw Palmetto Compound — through 1 ingredient. Tap an ingredient for the detail:
Stinging NettleAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Read the full Stinging Nettle + Alogliptin, Pioglitazone interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Saw Palmetto Compound — through 1 ingredient. Tap an ingredient for the detail:
Saw PalmettoAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Saw Palmetto Compound — through 1 ingredient. Tap an ingredient for the detail:
Saw PalmettoAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Saw Palmetto Compound — through 1 ingredient. Tap an ingredient for the detail:
Saw PalmettoAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Saw Palmetto Compound — through 1 ingredient. Tap an ingredient for the detail:
Stinging NettleDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Stinging Nettle + Amiloride, Hydrochlorothiazide interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with Saw Palmetto Compound — through 1 ingredient. Tap an ingredient for the detail:
Stinging NettleDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Stinging Nettle + Ammonium Chloride interactionAnacaulase-bcdbNexoBrid
How Anacaulase-bcdb interacts with Saw Palmetto Compound — through 1 ingredient. Tap an ingredient for the detail:
Saw PalmettoAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto + Anacaulase-bcdb interactionAnagrelideAgrylin
How Anagrelide interacts with Saw Palmetto Compound — through 1 ingredient. Tap an ingredient for the detail:
Saw PalmettoAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto + Anagrelide interactionAnisindioneMiradon
How Anisindione interacts with Saw Palmetto Compound — through 1 ingredient. Tap an ingredient for the detail:
Saw PalmettoAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto + Anisindione interactionAntidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi
How Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interacts with Saw Palmetto Compound — through 1 ingredient. Tap an ingredient for the detail:
Stinging NettleAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Read the full Stinging Nettle + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionAntithrombin IiiThrombate III
How Antithrombin Iii interacts with Saw Palmetto Compound — through 1 ingredient. Tap an ingredient for the detail:
Saw PalmettoAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto + Antithrombin Iii interactionApixabanEliquis
How Apixaban interacts with Saw Palmetto Compound — through 1 ingredient. Tap an ingredient for the detail:
Saw PalmettoAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto + Apixaban interactionArgatrobanArgatroban
How Argatroban interacts with Saw Palmetto Compound — through 1 ingredient. Tap an ingredient for the detail:
Saw PalmettoAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto + Argatroban interactionAspirinAngettes 75, ASA, Asaphen, Aspirin, Caprin, Cartia +8 more
How Aspirin interacts with Saw Palmetto Compound — through 1 ingredient. Tap an ingredient for the detail:
Saw PalmettoAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto + Aspirin interactionAspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #3
How Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interacts with Saw Palmetto Compound — through 1 ingredient. Tap an ingredient for the detail:
Saw PalmettoAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto + Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Saw Palmetto Compound with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Saw Palmetto
Anticoagulant/Antiplatelet Drugs
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Saw palmetto is reported to prolong bleeding time. Theoretically, it might increase the risk of bleeding when used concomitantly with anticoagulant or antiplatelet drugs.
Contraceptive Drugs
Saw palmetto might reduce the effectiveness of contraceptive drugs.
Saw palmetto might have antiestrogenic effects. Theoretically, it might interfere with contraceptive drugs taken concomitantly.
Estrogens
Saw palmetto might reduce the effectiveness of estrogens.
Saw palmetto might have antiestrogenic effects. Theoretically, it might interfere with estrogens taken concomitantly.
Stinging Nettle
Antidiabetes Drugs
Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Clinical research shows that stinging nettle might decrease blood glucose levels in patients with diabetes.
Diuretic Drugs
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Animal research suggests that the above ground parts and roots of stinging nettle may have a diuretic effect.
Lithium
Theoretically, stinging nettle might reduce excretion and increase levels of lithium.
Animal research suggests that stinging nettle has diuretic and natriuretic properties, which could alter the excretion of lithium. The dose of lithium might need to be decreased.
Warfarin (Coumadin)
There is some concern that stinging nettle might decrease the effects of anticoagulant drugs such as warfarin.
Stinging nettle contains a significant amount of vitamin K. When taken in large quantities, this might interfere with the activity of warfarin.
Brand information
Manufacturer and brand details for Saw Palmetto Compound, from the product label.
Wise Woman Herbals
See all Wise Woman Herbals products- Name
- Wise Woman Herbals
- City
- Creswell
- State
- OR
- ZipCode
- 97426
- Phone Number
- 541.895.5152
- Web Address
- wisewomanherbals.com
Saw Palmetto Compound by Wise Woman Herbals: Common Questions
Does Saw Palmetto Compound by Wise Woman Herbals interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm pregnant or breastfeeding?
What are the most common side effects?
Does this actually work for prostate problems?
Why does it contain alcohol?
Can I use this long-term?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Saw Palmetto Compound is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Saw Palmetto Compound’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Saw Palmetto
Interacts with 174 drugsSaw palmetto is a plant extract most often used for urinary symptoms linked to an enlarged prostate (BPH). The best research suggests it works no better than a placebo for most men, though i...
Read the full Saw Palmetto monograph → Herb & supplement monographStinging Nettle
Interacts with 164 drugsStinging nettle is a common plant used as food and in traditional medicine, most often for prostate symptoms, allergies, and joint pain. The evidence is mixed and mostly preliminary, so it i...
Read the full Stinging Nettle monograph → Herb & supplement monographPipsissewa
Pipsissewa is a North American forest herb with a long history of traditional use as a diuretic and urinary remedy, but modern human research is very limited. There is not enough good eviden...
Read the full Pipsissewa monograph →Sources & How We Checked
Saw Palmetto Compound's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 46 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Saw Palmetto 22 references
- Wilt TJ, Ishani A, Stark G, et al. Saw palmetto extracts for treatment of benign prostatic hyperplasia: a systematic review. JAMA 1998;280:1604-9. PubMed
- Carraro JC, Raynaud JP, Koch G, et al. Comparison of phytotherapy (Permixon) with finasteride in the treatment of benign prostate hyperplasia: a randomized international study of 1,098 patients. Prostate 1996;29:231-40. DOI
- Di Silverio F, D'Eramo G, Lubrano C, et al. Evidence that Serenoa repens extract displays an antiestrogenic activity in prostatic tissue of benign prostatic hypertrophy patients. Eur Urol 1992;21:309-14. PubMed
- Stepanov VN, Siniakova LA, Sarrazin B, Raynaud JP. Efficacy and tolerability of the lipidosterolic extract of Serenoa repens (Permixon) in benign prostatic hyperplasia: a double-blind comparison of two dosage regimens. Adv Ther 1999;16:231-41.
- Cheema P, El-Mefty O, Jazieh AR. Intraoperative haemorrhage associated with the use of extract of Saw Palmetto herb: a case report and review of literature. J Intern Med 2001;250:167-9. PubMed
- Jibrin I, Erinle A, Saidi A, Aliyu ZY. Saw palmetto-induced pancreatitis. South Med J 2006;99:611-2. PubMed
- Prager N, Bickett K, French N, Marcovici G. A randomized, double-blind, placebo-controlled trial to determine the effectiveness of botanically derived inhibitors of 5-alpha-reductase in the treatment of androgenetic alopecia. J Altern Complement Med 2002
- Avins AL, Bent S, Staccone S, et al. A detailed safety assessment of a saw palmetto extract. Complement Ther Med 2008;16:147-54. PubMed
- Morgia, G., Mucciardi, G., Gali, A., Madonia, M., Marchese, F., Di, Benedetto A., Romano, G., Bonvissuto, G., Castelli, T., Macchione, L., and Magno, C. Treatment of chronic prostatitis/chronic pelvic pain syndrome category IIIA with Serenoa repens plus
- Aliaev, IuG, Vinarov, A. Z., Lokshin, K. L., and Spivak, L. G. [Efficiency and safety of prostamol-Uno in patients with chronic abacterial prostatitis]. Urologiia. 2006;(1):47-50.
- Agbabiaka, T. B., Pittler, M. H., Wider, B., and Ernst, E. Serenoa repens (saw palmetto): a systematic review of adverse events. Drug Saf 2009;32(8):637-647. PubMed
- Wargo, K. A., Allman, E., and Ibrahim, F. A possible case of saw palmetto-induced pancreatitis. South.Med.J. 2010;103(7):683-685. PubMed
- Lapi, F., Gallo, E., Giocaliere, E., Vietri, M., Baronti, R., Pieraccini, G., Tafi, A., Menniti-Ippolito, F., Mugelli, A., Firenzuoli, F., and Vannacci, A. Acute liver damage due to Serenoa repens: a case report. Br.J.Clin.Pharmacol. 2010;69(5):558-560.
- Mantovani, F. Serenoa repens in benign prostatic hypertrophy: analysis of 2 Italian studies. Minerva Urol.Nefrol. 2010;62(4):335-340.
- Hanaka, M., Yoshii, C., Yatera, K., Ito, C., Chojin, Y., Nagata, S., Yamasaki, K., Nishida, C., Kawanami, T., Kawanami, Y., Ishimoto, H., and Mukae, H. [A case of rhabdomyolysis caused by saw palmetto of healthy foods]. J.UOEH. 6-1-2012;34(2):193-199. PubMed
- Miroddi, M., Carni, A., Mannucci, C., Moleti, M., Navarra, M., and Calapai, G. Hot flashes in a young girl: a wake-up call concerning Serenoa repens use in children. Pediatrics 2012;130(5):e1374-e1376.
- Braeckman J. The extract of Serenoa repens in the treatment of benign prostatic hyperplasia: a multicenter open study. Current Therapeutic Research 1994;55(7):776-785. DOI
- Jipescu D, Patel A, Bohra H, Pientka A. Rare case of saw palmetto induced heart block. JACC 2017;69(11) supplement:2310.
- Morabito P, Miroddi M, Giovinazzo S, Spina E, Calapai G. Serenoa repens as an endocrine disruptor in a 10-year-Old young girl: a new case report. Pharmacology. 2015;96(1-2):41-3. doi: 10.1159/000431327.
- Gammoudi R, Ameur K, Ouni B, et al. Fixed drug eruption to Serenoa repens: first case report and consideration of the use of herbal medicine. Dermatol Ther 2020 Aug 29:e14247.
- Paulis G, Paulis A, Perletti G. Serenoa repens and its effects on male sexual function. A systematic review and meta-analysis of clinical trials. Arch Ital Urol Androl 2021;93(4):475-480. PubMed
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