No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Pipsissewa Non-Alcohol Ingredients & Drug Interactions

by Hawaii Pharm

Liquid Category: Botanical
No known interaction
The interaction bottom line No known interaction

Pipsissewa Non-Alcohol is a dietary supplement by Hawaii Pharm with 1 active ingredient. Its ingredients are commonly taken for urinary tract support, diuretic (increasing urine flow), mild inflammation.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Pipsissewa Non-Alcohol by Hawaii Pharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.

This product contains one active ingredient: wild harvested pipsissewa extract. Pipsissewa is a plant traditionally used in herbal medicine, though modern safety and effectiveness data for it are limited.

The liquid also contains vegetable palm glycerin and Hawaiian artesian water as inactive ingredients to deliver the extract.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Pipsissewa product and its label doesn't state a use — see Pipsissewa's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We don't have enough reliable evidence to rate pipsissewa for any of the conditions it's been traditionally used for—cancer, diabetes, epilepsy, kidney stones, or urinary tract infections. The research backing for this ingredient just isn't established in the data we hold.

If you're considering it for a specific health goal, talk that over with your doctor to explore what the evidence actually supports.

The evidence, ingredient by ingredient Pipsissewa

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Modern safety data for pipsissewa is limited. The bigger concern is that chronic long-term use of this extract could theoretically lead to hydroquinone toxicity (a compound naturally present in the plant), with symptoms ranging from vomiting to delirium, convulsions, and collapse.

The safety information isn't reliable enough—the data advises against use during pregnancy and while breastfeeding. If you're pregnant, planning to become pregnant, or nursing, skip this product and talk with your doctor about safer options.

Side effects, ingredient by ingredient Pipsissewa

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we checked. Even so, run your exact medications through the search tool before starting, and confirm with your own doctor or pharmacist that this product won't interfere with anything you take.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Pipsissewa has a long history in traditional medicine, but modern evidence for what it actually does—or how safe it is—is thin. The theoretical risk of toxicity with chronic use is real.

If you're interested in it, talk with your doctor or pharmacist first, especially if you're pregnant, breastfeeding, or taking any medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pipsissewa Non-Alcohol, straight from the product label.

Brand Hawaii Pharm
Barcode (UPC) 0748399918079
Net contents 4 Fluid Ounce(s); 120 mL
Market status Off market
Date entered into DSLD Oct 23, 2020
DSLD ID 238568
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pipsissewa Non-Alcohol by Hawaii Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
20 Drop(s)
Maximum serving Sizes:
30 Drop(s)
UPC/BARCODE
0748399918079
IngredientAmount% DV
wild harvested Pipsissewa extract0 NP--

Other ingredients: Vegetable Palm Glycerin, crystal clear artesian Hawaiian Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Hawaii Pharm Non-Alcohol Herbal Extract Highest quality since 2008

Made with Aloha!

Formulation

Contains no gluten, artificial colors, pesticides, preservatives, heavy metals. Non GMO.

Super concentrated liquid herbal extract Dry herb/menstruum ratio: 1:3

Contains no alcohol

Description: We produced this extract according to precise standards where each herbs are individually extracted according to their distinct characteristic. We use a cold maceration extraction method, so that the active constituents of the herbs are extracted and maintained.

Non GMO Gluten free

Manufactured in an FDA registered facility. Ultra Sonic

Made in USA, Hawaii

Suggested/Recommended/Usage/Directions

Directions for use: Shake well before using. Take about 20-30 drops in juice, water, tea or as desired up to four times per day.

Precautions

Warnings: Keep out of the reach of children.

Not to be used during pregnancy.

Do not use if you are allergic to any ingredients.

Consult a physician before using if nursing or taking medications.

Do not use if seal is broken or missing.

Storage

Refrigerate after opening.

Formula

(Chimaphila umbellata)

FDA Statement of Identity

Herbal Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

FDA Registered Facility Made in United States of America USA

See for yourself

Pipsissewa Non-Alcohol by Hawaii Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Pipsissewa Non-Alcohol by Hawaii Pharm

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size20 Drop(s) Dosage formLiquid Amounts shown are per serving.

Wild harvested Pipsissewa extract

No known
interactions
0 NP per serving

Pipsissewa is a North American forest herb with a long history of traditional use as a diuretic and urinary remedy, but modern human research is very...

Wild harvested Pipsissewa extract monograph & interactions

Other (inactive) ingredients: Vegetable Palm Glycerin, Crystal clear artesian Hawaiian Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pipsissewa Non-Alcohol by Hawaii Pharm Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Pipsissewa Non-Alcohol. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Pipsissewa Non-Alcohol, from the product label.

Hawaii Pharm

See all Hawaii Pharm products
Name
Hawaii Pharm LLC
City
Honolulu
State
HI
ZipCode
96815
Pharmacist Counseling Corner

Pipsissewa Non-Alcohol by Hawaii Pharm: Common Questions

Does Pipsissewa Non-Alcohol by Hawaii Pharm interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Pipsissewa Non-Alcohol. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Pipsissewa Non-Alcohol contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while I'm pregnant or breastfeeding?
No. The safety data advises against using pipsissewa during pregnancy and while breastfeeding. There isn't enough reliable information to know it's safe for you or your baby. Talk with your doctor about what to use instead.
What are the side effects if I take it for a long time?
Chronic long-term use could theoretically lead to hydroquinone toxicity from a compound naturally in the plant. Symptoms may include vomiting, delirium, convulsions, and collapse. Modern safety data on this are limited, so long-term use isn't well understood.
Does pipsissewa actually work for kidney stones or urinary tract infections?
We don't have enough reliable evidence to rate it. Pipsissewa has been used traditionally for these conditions, but the science backing it up just isn't established in the data we hold.
Is this product safe to take with my medications?
We hold no documented interactions between pipsissewa and medications. That said, use the search tool on this page to check your exact drugs, and confirm with your doctor or pharmacist before you start.
What is pipsissewa?
Pipsissewa is a plant used in traditional herbal medicine. This product is a wild harvested extract delivered in a liquid form with vegetable glycerin and Hawaiian water.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pipsissewa Non-Alcohol is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pipsissewa Non-Alcohol label
Go deeper

The Full Monographs Behind Pipsissewa Non-Alcohol’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Pipsissewa Non-Alcohol's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Pipsissewa 2 references
  1. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

See these in context on the Pipsissewa monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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