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Dietary supplement

Pleurisy Root Ingredients & Drug Interactions

by Herb Pharm

Pleurisy Root label
See full label image
Liquid Category: Botanical
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Pleurisy Root against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Pleurisy Root is a dietary supplement by Herb Pharm with 1 active ingredient. Its ingredients are commonly taken for respiratory congestion, pleurisy and chest discomfort, coughs and bronchitis.Based on those ingredients, 117 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Pleurisy Root root (Asclepias tuberosa) extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Pleurisy Root by Herb Pharm

Ask about any prescription or over-the-counter medication and we check it for interactions with Pleurisy Root by Herb Pharm — and tell you which ingredient is responsible.

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Computed from our clinical databases

HelloPharmacist Scorecard of Pleurisy Root by Herb Pharm

Four independent checks of what is known — a summary of the available information, not a grade of the product itself.

Evidence for Intended Use
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

The stated purpose hasn't been mapped to our evidence data yet.

Why this rating?
  • We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Ingredient Transparency
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.
Known Interaction Concern
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Pleurisy Root.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: heart-rhythm medications.
  • For scale: 117 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Safety Information
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Major medication interactions have been identified, and safety information is well characterized.

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 21, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pleurisy Root, straight from the product label.

Brand Herb Pharm
Barcode (UPC) 090800000102
Net contents 1 fl. Oz.; 30 mL
Market status On market
Date entered into DSLD Nov 21, 2018
DSLD ID 183685
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Organic, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pleurisy Root by Herb Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.7 mL
Maximum serving Sizes:
0.7 mL
Servings per container
42
UPC/BARCODE
090800000102
IngredientAmount% DV
Pleurisy Root root (Asclepias tuberosa) extract665 mg--

Other ingredients: certified organic Cane Alcohol, distilled Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use Shake Well Before Using Add 1 full squeeze of the dropper bulb to 2 oz. of water or juice, 2 to 4 times per day. Best taken between meals.

Precautions

Caution: Seek expert medical advice before taking during pregnancy.

Keep Out of the Reach of Children

Storage

Store away from heat & light

General

011

Formula

Asclepias tuberosa

Pleurisy Root Liquid Extract

General Statements

Respiratory system

Dry herb / menstruum ratio: 1:4

Seals/Symbols

USDA Organic

FDA Statement of Identity

Herbal Supplement

Formulation

Gluten-Free

Prepared from the root of Asclepias tuberosa plants which are certified organically grown on our farm. Certified organic by Organic Certifiers

FDA Disclaimer Statement

This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Pleurisy Root by Herb Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Pleurisy Root label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Pleurisy Root by Herb Pharm

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.7 mL Dosage formLiquid Servings per container42 Amounts shown are per serving.

Pleurisy Root root (Asclepias tuberosa) extract

Interacts with
117 drugs
665 mg per serving

Pleurisy root is the dried root of Asclepias tuberosa (butterfly weed), a plant used in traditional North American and herbal medicine mainly for resp...

Pleurisy Root root (Asclepias tuberosa) extract monograph & interactions

Other (inactive) ingredients: Certified organic Cane Alcohol, Distilled Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pleurisy Root by Herb Pharm Drug Interactions

Pleurisy Root contains a single active ingredient, and it has known interactions with 117 medications. Here’s the picture, then you can look up your own drug.

Want to check YOUR meds against Pleurisy Root?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
117Drugs
1 Major 116 Moderate

Ingredients driving the most interactions

Pleurisy Root root (Asclepias tuberosa) extract 117

Individual Drug Interactions

The ingredients in Pleurisy Root interact with 117 drugs. Click any drug to see the details.

1 of the 1 ingredient in Pleurisy Root interact with drugs. Each result below shows which ingredient is responsible. Pleurisy Root root (Asclepias tuberosa) extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Pleurisy Root with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Pleurisy Root root (Asclepias tuberosa) extract3 drug types · 117 drugs

Digoxin (Lanoxin)

Pleurisy root contains digitalis-like cardenolide glycosides. Taking pleurisy root in combination with digoxin could increase the risk of adverse effects and toxicity.

Likelihood Probable Evidence D
Diuretic Drugs

Theoretically, concomitant use of potassium-depleting diuretics and pleurisy root can increase the risk of cardiac glycoside toxicity due to potassium depletion. Some diuretics that can deplete potassium include chlorothiazide (Diuril), chlorthalidone (Thalitone), furosemide (Lasix), hydrochlorothiazide (HCTZ, Hydrodiuril, Microzide), and others.

Likelihood Possible Evidence D
Estrogens

Theoretically, excessive amounts of pleurisy root might interfere with hormone drug therapy.

Likelihood Possible Evidence D
Pleurisy Root root (Asclepias tuberosa) extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Pleurisy Root, from the product label.

Herb Pharm

See all Herb Pharm products
Name
Herb Pharm
City
Williams
State
OR
ZipCode
97544
Phone Number
800-348-4372
Web Address
www.herb-pharm.com
Pharmacist Counseling Corner

Pleurisy Root by Herb Pharm: Common Questions

Does Pleurisy Root by Herb Pharm interact with any medications?
Yes. Based on its ingredients, Pleurisy Root has a known interaction with 117 medications, including 1 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Pleurisy Root contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pleurisy Root is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pleurisy Root label
Go deeper

The Full Monographs Behind Pleurisy Root’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Pleurisy Root

Interacts with 117 drugs

Pleurisy root is the dried root of Asclepias tuberosa (butterfly weed), a plant used in traditional North American and herbal medicine mainly for respiratory complaints. There is very little...

Read the full Pleurisy Root monograph →
Sources

Sources & How We Checked

Pleurisy Root's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Pleurisy Root 7 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  3. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  4. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  5. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  6. Gossel TA, Bricker JD. Principles of Clinical Toxicology. New York, NY:Raven Press, 1994.
  7. De Smet PAGM, Keller K, Hansel R, Chandler RF, Eds. Adverse Effects of Herbal Drugs 1. Verlag, Berlin: Springer, 1992. DOI

See these in context on the Pleurisy Root monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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