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Dietary supplement

PMS Gummy Acai Berry Ingredients & Drug Interactions

by Aura Essentials

PMS Gummy Acai Berry label
See full label image
Gummy Or Jelly Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking PMS Gummy Acai Berry against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

PMS Gummy Acai Berry is a dietary supplement by Aura Essentials with 3 active ingredients. Its ingredients are commonly taken for premenstrual syndrome (pms), irregular or absent menstrual periods, cyclical breast pain (mastalgia).Based on those ingredients, 643 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Dandelion Whole Herb Extract, Pine bark extract, Chasteberry Fruit Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against PMS Gummy Acai Berry by Aura Essentials

Ask about any prescription or over-the-counter medication and we check it for interactions with PMS Gummy Acai Berry by Aura Essentials — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of PMS Gummy Acai Berry by Aura Essentials

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

PMS Gummy Acai Berry contains 3 active ingredients. Chasteberry fruit extract is used traditionally for premenstrual syndrome and related symptoms, while pine bark extract is added for circulatory support and joint comfort.

Dandelion whole herb extract rounds out the blend as a traditional digestive and wellness herb. The gummy also contains inactive ingredients including sugar, corn syrup, acai berry pulp, pectin, fruit juice, vegetable juice, citric acid, natural flavor, salt, vanilla, and purified water.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: supports premenstrual syndrome and skin health.
  • We looked for evidence on: Premenstrual syndrome (PMS), Mastalgia, Aging skin, Acne, Wrinkled skin, menstrual cycle regulation — and 1 related terms.
  • The strongest evidence on file: Vitex Agnus-castus is rated "Possibly Effective" for Mastalgia (Natural Medicines).
  • Also on file: Vitex Agnus-castus is rated "Possibly Effective" for Premenstrual syndrome (PMS).
  • Also on file: Vitex Agnus-castus is rated "Insufficient Reliable Evidence To Rate" for Acne, Aging skin.

Chasteberry has possibly effective evidence for premenstrual syndrome (PMS) and mastalgia (breast tenderness), though evidence for premenstrual dysphoric disorder (PMDD) and anxiety is not yet established. Pine bark extract is possibly effective for osteoarthritis and chronic venous insufficiency (poor circulation in the legs).

Dandelion's effectiveness for joint pain, tonsillitis, and postoperative swelling is not yet established in the data we hold. The product is marketed for PMS, where chasteberry has the strongest evidence base.

The evidence, ingredient by ingredient Vitex Agnus-castus Maritime Pine Dandelion

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Chasteberry is generally well tolerated for short-term use but may affect hormones, so use under guidance. Reported side effects include diarrhea, fatigue, headache, insomnia, irregular menstruation, nausea, stomach pain, and skin irritation.

Pine bark extract is generally well tolerated, though gastrointestinal complaints, dizziness, and vertigo have been reported; long-term safety is not fully established. Dandelion is well tolerated as food but at supplement doses may cause diarrhea, heartburn, stomach discomfort, or contact dermatitis.

Rare allergic reactions including anaphylaxis are possible if you're sensitive to the daisy family (ragweed, chrysanthemums, marigolds, daisies). Chasteberry is rated possibly unsafe in pregnancy and should be avoided while breastfeeding due to possible hormonal effects and limited safety data.

Pine bark extract lacks enough safety data for pregnancy or breastfeeding — talk with your doctor. Dandelion has insufficient data for breastfeeding safety; it has not been rated for pregnancy in our data, so check with your doctor before use.

Side effects, ingredient by ingredient Vitex Agnus-castus Maritime Pine Dandelion

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Dandelion, Vitex Agnus-castus, Maritime Pine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications; lithium.
  • For scale: 643 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking PMS Gummy Acai Berry, check with your doctor or pharmacist if you use oral contraceptives, hormone replacement therapy (estrogens), antipsychotic drugs (such as haloperidol or risperidone), blood thinners or antiplatelet drugs (such as warfarin or aspirin), diabetes medications, dopamine agonists, water pills (especially potassium-sparing types), lithium, fluoroquinolone antibiotics (such as ciprofloxacin), metoclopramide (Reglan), or medications metabolized by the liver enzyme CYP1A2. No interactions are documented for the specific dosage form and brand of this product in controlled human studies, but the individual ingredients do carry documented risks with these medication types.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product may help with PMS symptoms, especially through its chasteberry content, but it carries several Moderate-severity interactions with common medications like birth control, blood thinners, diabetes drugs, and psychiatric medicines. If you take any prescription drugs, check them against the interaction tool on this page and discuss the results with your doctor or pharmacist before starting.

Avoid during pregnancy and breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 14, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about PMS Gummy Acai Berry, straight from the product label.

Brand Aura Essentials
Net contents 60 Gummy(ies)
Market status On market
Date entered into DSLD Dec 14, 2023
DSLD ID 303577
Product type Botanical
Supplement form Gummy Or Jelly
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Women (not pregnant or lactating), Girls: (All), Adult Female (18 - 50 Years), Seniors/Mature (>50 Years) - Women ONLY
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for PMS Gummy Acai Berry by Aura Essentials, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Gummy(ies)
Maximum serving Sizes:
2 Gummy(ies)
Servings per container
30
IngredientAmount% DV
Calories25 Calorie(s)--
Total Carbohydrates6 Gram(s)2%
Added Sugars4 Gram(s)8%
Total Sugars4 Gram(s)--
Chasteberry Fruit Extract40 mg--
Pine bark extract150 mg--
Dandelion Whole Herb Extract60 mg--

Other ingredients: Sugar, Corn Syrup, Salt, Vanilla, Water, Acai Berry Pulp, Water, Purified, Pectin, Citric Acid, Natural flavor, Fruit Juice, Vegetable Juice

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Promotes healthy blood flow Supports productivity and focus Promotes healthy skin and collagen

Completely Clean Cruelty-Free

Non-GMO

Vegan

FDA Statement of Identity

Dietary Supplement

Precautions

Warning: not to be used during pregnancy or nursing.

Use during hormone therapy, including birth control should be done under the supervision of your physician.

If you have any health condition or are taking medication, consult your health professional before use.

Keep out of reach of children.

Use only if safety seal is intact.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

PMS Gummy Acai Berry by Aura Essentials label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

PMS Gummy Acai Berry label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in PMS Gummy Acai Berry by Aura Essentials

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Gummy(ies) Dosage formGummy Or Jelly Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Chasteberry Fruit Extract

Interacts with
121 drugs
40 mg per serving

Vitex (chasteberry) is an herbal remedy most often used for PMS and menstrual cycle problems, and the strongest evidence is for easing some PMS sympto...

Chasteberry Fruit Extract monograph & interactions

Pine bark extract

Interacts with
327 drugs
150 mg per serving

Maritime pine bark extract (often sold as Pycnogenol) is a plant-based antioxidant most studied for circulation, vein, and skin health. Some research...

Pine bark extract monograph & interactions

Dandelion Whole Herb Extract

Interacts with
457 drugs
60 mg per serving

Dandelion is a common plant used in food and traditional medicine, often promoted as a natural 'water pill' and digestive aid. Human evidence for thes...

Dandelion Whole Herb Extract monograph & interactions

Other (inactive) ingredients: Sugar, Corn Syrup, Salt, Vanilla, Water, Acai Berry Pulp, Water, Purified, Pectin, Citric Acid, Natural flavor, Fruit Juice, Vegetable Juice. These complete the product’s ingredient list but are not active constituents.

Interaction report

PMS Gummy Acai Berry by Aura Essentials Drug Interactions

Want to check YOUR meds against PMS Gummy Acai Berry?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
643Drugs
643 Moderate

Ingredients driving the most interactions

Dandelion Whole Herb Extract 457
Pine bark extract 327
Chasteberry Fruit Extract 121

Individual Drug Interactions

The ingredients in PMS Gummy Acai Berry interact with 643 drugs. Click any drug to see the details.

3 of the 3 ingredients in PMS Gummy Acai Berry interact with drugs. Each result below shows which ingredient is responsible. Dandelion Whole Herb Extract Pine bark extract Chasteberry Fruit Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in PMS Gummy Acai Berry with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Dandelion Whole Herb Extract7 drug types · 457 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, taking dandelion root along with anticoagulant or antiplatelet drugs might increase the risk of bruising and bleeding.
In vitro research suggests that dandelion root inhibits platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, dandelion might increase the risk for hypoglycemia when used with antidiabetes drugs.
Laboratory research suggests that dandelion extract may have moderate alpha-glucosidase inhibitor activity and might also increase insulin secretion. Also, in a case report, a 58-year-old woman with type 2 diabetes who was being treated with insulin developed hypoglycemia 2 weeks after beginning to eat salads containing dandelion.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, dandelion might increase levels of drugs metabolized by CYP1A2.
Laboratory research suggests that dandelion might inhibit CYP1A2. So far, this interaction has not been reported in humans. However, until more is known, watch for an increase in the levels of drugs metabolized by CYP1A2 in patients taking dandelion.

Likelihood Possible Evidence D
Glucuronidated Drugs

Theoretically, dandelion might increase the clearance of drugs that are UDP-glucuronosyltransferase substrates.
There is some preliminary evidence that dandelion might induce UDP-glucuronosyltransferase, a phase II enzyme.

Likelihood Possible Evidence D
Lithium

Theoretically, through diuretic effects, dandelion might reduce excretion and increase levels of lithium.
Animal research suggests that dandelion has diuretic properties. As diuretics can increase serum lithium levels, the dose of lithium might need to be decreased when taken with dandelion.

Likelihood Probable Evidence D
Potassium-Sparing Diuretics

Theoretically, dandelion might increase the risk of hyperkalemia when taken with potassium-sparing diuretics.
Dandelion contains significant amounts of potassium.

Likelihood Possible Evidence D
Quinolone Antibiotics

Theoretically, dandelion might lower fluoroquinolone levels.
Animal research shows that dandelion reduces absorption of ciprofloxacin and can lower levels by 73%. However, this effect has not been reported in humans.

Likelihood Possible Evidence D
Dandelion Whole Herb Extract full monograph & interactions

Pine bark extract3 drug types · 327 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, maritime pine bark extract might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Clinical research suggests that maritime pine bark extract inhibits platelet aggregation. However, the clinical significance of this effect is unclear.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, maritime pine bark extract might increase the risk of hypoglycemia when used with antidiabetes drugs.
One clinical study shows that maritime pine bark extract decreases blood sugar in patients with diabetes being treated with antidiabetes agents. Monitor blood glucose levels closely. Dose adjustments might be necessary.

Likelihood Possible Evidence B
Immunosuppressants

Theoretically, maritime pine bark extract might decrease the effectiveness of immunosuppressant therapy.
In vitro and animal research suggests that maritime pine bark extract has immunostimulant activity. This effect has not been reported in humans.

Likelihood Possible Evidence D
Pine bark extract full monograph & interactions

Chasteberry Fruit Extract5 drug types · 121 drugs

Antipsychotic Drugs

Theoretically, vitex agnus-castus could interfere with the activity of antipsychotic drugs.
Vitex agnus-castus might interfere with the action of dopamine antagonists such as antipsychotic drugs due to its dopamine agonist effects.

Likelihood Possible Evidence D
Contraceptive Drugs

Theoretically, vitex agnus-castus could interfere with oral contraceptives.
Vitex agnus-castus might interfere with the efficacy of oral contraceptives due to possible hormone modulating activity.

Likelihood Possible Evidence B
Dopamine Agonists

Theoretically, vitex agnus-castus could interfere with dopamine agonists.
Vitex agnus-castus might potentiate the actions of dopaminergic agonists due to possible dopaminergic effects.

Likelihood Possible Evidence D
Estrogens

Theoretically, vitex agnus-castus could interfere with the activity of estrogens.
Vitex agnus-castus has hormone modulating activity that can interfere with the efficacy of hormone replacement therapy.

Likelihood Probable Evidence D
Metoclopramide (Reglan)

Theoretically, dopaminergic effects of vitex agnus-castus could interfere with metoclopramide.
Vitex agnus-castus might interfere with the action of dopamine antagonists such as metoclopramide due to its possible dopaminergic effects.

Likelihood Possible Evidence D
Chasteberry Fruit Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for PMS Gummy Acai Berry, from the product label.

Aura Essentials

See all Aura Essentials products
Name
Aura Essentials
Pharmacist Counseling Corner

PMS Gummy Acai Berry by Aura Essentials: Common Questions

Does PMS Gummy Acai Berry by Aura Essentials interact with any medications?
Yes. Based on its ingredients, PMS Gummy Acai Berry has a known interaction with 643 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
PMS Gummy Acai Berry contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe during pregnancy or breastfeeding?
No. Chasteberry is rated possibly unsafe during pregnancy and should be avoided while breastfeeding because of possible hormonal effects and limited safety data. Pine bark extract lacks enough safety data for both pregnancy and breastfeeding. Dandelion has insufficient data for breastfeeding. Talk with your doctor or pharmacist before use if you are pregnant, planning to become pregnant, or breastfeeding.
Can this interfere with birth control?
Yes. Chasteberry may interfere with the effectiveness of oral contraceptives through its hormone-modulating activity. This is a Moderate-severity interaction, so talk with your doctor or pharmacist before combining them.
What are the most common side effects?
Chasteberry may cause diarrhea, fatigue, headache, insomnia, irregular menstruation, nausea, and stomach pain. Pine bark extract may cause gastrointestinal complaints, dizziness, and vertigo. Dandelion may cause diarrhea, heartburn, and stomach discomfort. Most people tolerate these ingredients well, but report any side effects to your doctor or pharmacist.
Does this actually work for PMS?
Chasteberry, the main active ingredient, has possibly effective evidence for premenstrual syndrome and breast tenderness. That means research supports it may help, but larger and longer studies are still needed. Results vary from person to person.
What is dandelion in here for?
Dandelion is a traditional herb used for digestive and wellness support. It's included as part of the supplement blend, though evidence for its specific effects on PMS is not yet established in the data we hold.
Does this product have any fillers?
Yes. The gummy contains inactive ingredients including sugar, corn syrup, pectin, fruit juice, vegetable juice, citric acid, natural flavor, salt, vanilla, and purified water used to form and flavor the gummy.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

PMS Gummy Acai Berry label
Go deeper

The Full Monographs Behind PMS Gummy Acai Berry’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vitex Agnus-castus

Interacts with 121 drugs

Vitex (chasteberry) is an herbal remedy most often used for PMS and menstrual cycle problems, and the strongest evidence is for easing some PMS symptoms. It is generally well tolerated by ma...

Read the full Vitex Agnus-castus monograph → Herb & supplement monograph

Maritime Pine

Interacts with 327 drugs

Maritime pine bark extract (often sold as Pycnogenol) is a plant-based antioxidant most studied for circulation, vein, and skin health. Some research is promising, but many studies are small...

Read the full Maritime Pine monograph → Herb & supplement monograph

Dandelion

Interacts with 457 drugs

Dandelion is a common plant used in food and traditional medicine, often promoted as a natural 'water pill' and digestive aid. Human evidence for these uses is very limited, so its benefits...

Read the full Dandelion monograph →
Sources

Sources & How We Checked

PMS Gummy Acai Berry's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 64 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitex Agnus-castus 23 references
  1. Wuttke W. Dopaminergic action of extracts of Agnus Castus. Forschende Komplementarmedizen 1996;3:329-30.
  2. Jarry H, Leonhardt S., Gorkow C, Wuttke W. In vitro prolactin but not LH and FSH release is inhibited by compounds in extracts of Agnus Castus: direct evidence for a dopaminergic principle by the dopamine receptor assay. Exp Clin Endocrinol 1994;102:448- PubMed
  3. Schellenberg R. Treatment for the premenstrual syndrome with agnus castus fruit extract: prospective, randomised, placebo-controlled study. BMJ 2001;322:134-7. PubMed
  4. Lauritzen CH, Reuter HD, Repges R, et al. Treatment of premenstrual tension syndrome with Vitex agnus castus: Controlled-double blind versus pyridoxine. Phytomedicine 1997;4:183-9.
  5. Berger D, Schaffner W, Schrader E, et al. Efficacy of Vitex agnus castus L. extract Ze 440 in patients with premenstrual syndrome (PMS). Arch Gynecol Obstet 2000;264:150-3.
  6. Loch EG, Selle H, Boblitz N. Treatment of premenstrual syndrome with a phytopharmaceutical formulation containing Vitex agnus castus. J Womens Health Gend Based Med 2000;9:315-20. PubMed
  7. Meier B, Berger D, Hoberg E, et al. Pharmacological activities of Vitex agnus-castus extracts in vitro. Phytomedicine 2000;7:373-81. PubMed
  8. Liu J, Burdette JE, Xu H, et al. Evaluation of estrogenic activity of plant extracts for the potential treatment of menopausal symptoms. J Agric Food Chem 2001;49:2472-9.. PubMed
  9. Wuttke W, Jarry H, Christoffel V, et al. Chaste tree (Vitex agnus-castus)--pharmacology and clinical indications. Phytomedicine 2003;10:348-57. PubMed
  10. Atmaca M, Kumru S, Tezcan E. Fluoxetine versus Vitex agnus castus extract in the treatment of premenstrual dysphoric disorder. Hum Psychopharmacol 2003;18:191-5..
  11. Daniele C, Thompson Coon J, Pittler MH, Ernst E. Vitex agnus castus: a systematic review of adverse events. Drug Saf 2005;28:319-32..
  12. Halaska M, Beles P, Gorkow C, Sieder C. Treatment of cyclical mastalgia with a solution containing a Vitex agnus castus extract: results of a placebo-controlled double-blind study. Breast 1999;8:175-81. PubMed
  13. Prilepskaya VN, Ledina AV, Tagiyeva AV, Revazova FS. Vitex agnus castus: Successful treatment of moderate to severe premenstrual syndrome. Maturitas 2006;55 Suppl 1:S55-63. DOI
  14. Ma, L., Lin, S., Chen, R., and Wang, X. Treatment of moderate to severe premenstrual syndrome with Vitex agnus castus (BNO 1095) in Chinese women. Gynecol.Endocrinol. 2010;26(8):612-616. PubMed
  15. Ma, L., Lin, S., Chen, R., Zhang, Y., Chen, F., and Wang, X. Evaluating therapeutic effect in symptoms of moderate-to-severe premenstrual syndrome with Vitex agnus castus (BNO 1095) in Chinese women. Aust.N.Z.J Obstet.Gynaecol. 2010;50(2):189-193. PubMed
  16. Dinç T, Coskun F. Comparison of fructus agni casti and flurbiprofen in the treatment of cyclic mastalgia in premenopausal women. Ulus Cerrahi Derg. 2014 Mar 1;30(1):34-8 PubMed
  17. Momoeda M, Sasaki H, Tagashira E, Ogishima M, Takano Y, Ochiai K. Efficacy and safety of Vitex agnus-castus extract for treatment of premenstrual syndrome in Japanese patients: a prospective, open-label study. Adv Ther. 2014 Mar;31(3):362-73. PubMed
  18. Yavarikia P, Shahnazi M, Hadavand Mirzaie S, Javadzadeh Y, Lutfi R. Comparing the effect of mefenamic Acid and vitex agnus on intrauterine device induced bleeding. J Caring Sci. 2013 Aug 31;2(3):245-54.
  19. Van Die MD, Burger HC, Teede HG, Bone KM. Vitex agnus castus extracts for female reproductive disorders: a systematic review of clinical trials. Planta Med 2013:79:562-575. PubMed
  20. Ooi SL, Watts S, McClean R, Pak SC. Vitex agnus-castus for the treatment of cyclic mastalgia: A systematic review and meta-analysis. J Womens Health (Larchmt). 2020;29(2):262-278. PubMed
  21. Mollazadeh S, Mirghafourvand M, Abdollahi NG. The effects of Vitex agnus-castus on menstrual bleeding: A systematic review and meta-analysis. J Complement Integr Med. 2019;17(1). pii: /j/jcim.2019.17.issue-1/jcim-2018-0053/jcim-2018-0053.xml.
  22. Najib FS, Poordast T, Mahmudi MS, Shiravani Z, Namazi N, Omrani GR. Does Vitex Agnus-Castus L. Have Deleterious Effect on Fertility and Pregnancy Outcome? An Experimental Study on Rats for Prediction of Its Safety. J Pharmacopuncture 2022;25(2):106-113. PubMed
  23. Somuncu E, Solak IHA. Colonic Obstruction Secondary to Phytobezoar Caused by Vitex Agnus-Castus Seeds: A Case Report. J Coll Physicians Surg Pak 2022;32(8):S115-S117. PubMed

See these in context on the Vitex Agnus-castus monograph →

Maritime Pine 14 references
  1. Rice-Evans CA, Packer L, eds. Flavonoids in Health and Disease. Manhattan, NY: Marcel Dekker, Inc., 1998.
  2. Liu FJ, Zhang YX, Lau BH. Pycnogenol enhances immune and haemopoietic functions in senescence-accelerated mice. Cell Mol Life Sci 1998;54:1168-72. PubMed
  3. Putter M, Grotemeyer KH, Wurthwein G, et al. Inhibition of smoking-induced platelet aggregation by aspirin and pycnogenol. Thromb Res 1999;95:155-61. PubMed
  4. Kohama T, Inoue M. Pycnogenol alleviates pain associated with pregnancy. Phytother Res 2006;20:232-4.
  5. Liu X, Zhou HJ, Rohdewald P. French maritime pine bark extract pycnogenol dose-dependently lowers glucose in type 2 diabetic patients (letter). Diabetes Care 2004;27:839. PubMed
  6. Liu X, Wei J, Tan F, et al. Antidiabetic effect of Pycnogenol French maritime pine bark extract in patients with diabetes type II. Life Sci 2004;75:2505-13. PubMed
  7. Wilson D, Evans M, Guthrie N et al. A randomized, double-blind, placebo-controlled exploratory study to evaluate the potential of pycnogenol for improving allergic rhinitis symptoms. Phytother Res 2010;24:1115-9.
  8. Araghi-Niknam, M., Hosseini, S., Larson, D., Rohdewald, P., and Watson, R. R. Pine bark extract reduces platelet aggregation. Integr.Med. 3-21-2000;2(2):73-77. PubMed
  9. Trebaticka, J., Kopasova, S., Hradecna, Z., Cinovsky, K., Skodacek, I., Suba, J., Muchova, J., Zitnanova, I., Waczulikova, I., Rohdewald, P., and Durackova, Z. Treatment of ADHD with French maritime pine bark extract, Pycnogenol. Eur.Child Adolesc.Psychi PubMed
  10. Suzuki, N., Uebaba, K., Kohama, T., Moniwa, N., Kanayama, N., and Koike, K. French maritime pine bark extract significantly lowers the requirement for analgesic medication in dysmenorrhea: a multicenter, randomized, double-blind, placebo-controlled study
  11. Cisar, P., Jany, R., Waczulikova, I., Sumegova, K., Muchova, J., Vojtassak, J., Durackova, Z., Lisy, M., and Rohdewald, P. Effect of pine bark extract (Pycnogenol) on symptoms of knee osteoarthritis. Phytother.Res. 2008;22(8):1087-1092.
  12. Enseleit, F., Sudano, I., Periat, D., Winnik, S., Wolfrum, M., Flammer, A. J., Frohlich, G. M., Kaiser, P., Hirt, A., Haile, S. R., Krasniqi, N., Matter, C. M., Uhlenhut, K., Hogger, P., Neidhart, M., Luscher, T. F., Ruschitzka, F., and Noll, G. Effects
  13. Schoonees, A., Visser, J., Musekiwa, A., and Volmink, J. Pycnogenol(R) (extract of French maritime pine bark) for the treatment of chronic disorders. Cochrane.Database.Syst.Rev. 2012;4:CD008294.
  14. Wang S, Tan D Zhao Y et al. The effect of pycnogenol on the microcirculation, platelet function and ischemic myocardium in patients with coronary artery diseases. Eur Bull Drug Res 1999;7:19-25.

See these in context on the Maritime Pine monograph →

Dandelion 27 references
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See these in context on the Dandelion monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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