Prebiotic Ingredients & Drug Interactions
by Swanson
What is this page for?
First and foremost: checking Prebiotic against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Prebiotic is a dietary supplement by Swanson with 1 active ingredient. Its ingredients are commonly taken for digestive and gut health, prebiotic to support good bacteria, constipation relief.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Prebiotic by Swanson
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: NutraFlora scFOS, a branded form of fructo-oligosaccharides (FOS). FOS is a prebiotic fiber — it's a type of carbohydrate that feeds the beneficial bacteria in your gut.
The capsule also contains inactive ingredients (hypromellose, microcrystalline cellulose, calcium laurate, and silica) that serve as the capsule material and binding agents.
Does it work?
Not established
The evidence for FOS and what it can do isn't established yet in the data we hold. Studies haven't produced reliable findings on whether it helps with osteoporosis, constipation, blood sugar control, travelers' diarrhea, or cholesterol levels.
If you're thinking about taking it for one of those reasons, talking it over with your doctor can help you decide whether it makes sense for you.
How safe is it?
Well-documented data
FOS is generally well tolerated, especially in the amounts you'd eat in food. The main side effects are digestive — abdominal pain, bloating, gas, and intestinal sounds.
These tend to be mild at doses under 10 grams daily, and a review of clinical studies found that FOS at doses between 2.5 and 15 grams per day for up to 8 weeks didn't increase these symptoms compared to placebo. That said, supplement-level doses haven't been studied extensively, so if you're considering this product, it's worth checking with your doctor first.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredients we could check. That doesn't mean none exist — it just means the research we hold shows none so far.
If you take any medications, it's still a good idea to run them through the tool on this page or ask your pharmacist before you start.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.
Swanson Prebiotic is a straightforward prebiotic supplement with no documented medication interactions. Because the evidence for what FOS actually does is still incomplete, and because digestive side effects are possible (especially at higher doses), talk it over with your doctor or pharmacist before starting — they can help you figure out if it's a fit for what you're hoping to address.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 21, 2019.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Prebiotic, straight from the product label.
| Brand | Swanson |
|---|---|
| Barcode (UPC) | 087614190495 |
| Net contents | 30 Veggie Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Nov 21, 2019 |
| DSLD ID | 206405 |
| Product type | Fiber And Other Nutrients |
| Supplement form | Capsule |
| Dietary claims / uses | Nutrient, All Other |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Prebiotic by Swanson, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Total Carbohydrates | 1 Gram(s) | 1% |
| Total Sugars | 1 Gram(s) | -- |
| NutraFlora scFOS | 750 mg | -- |
Other ingredients: Hypromellose, Microcrystalline Cellulose, Calcium Laurate, Silica
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
For friendly flora support
FDA Statement of Identity
Dietary Supplement
Formula
NutraFlora Prebiotic - Soluble Fiber
Suggested/Recommended/Usage/Directions
Suggested Use: As a dietary supplement, take two veggie capsules per day in the morning, preferably with a Probiotic.
Brand IP Statement(s)
NutraFlora and scFOS are registered trademarks of the Ingredion group of companies.
Precautions
Note: Package contains desiccant packet to maintain freshness. Do not eat the desiccant packet. Do not use if seal is broken.
Keep out of reach of children.
Storage
Store in a cool, dry place.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Prebiotic by Swanson label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Prebiotic by Swanson
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size2 Veggie Capsule(s) Dosage formCapsule Servings per container15 Amounts shown are per serving.
NutraFlora scFOS
No knowninteractions
Fructo-oligosaccharides (FOS) are a type of soluble fiber that acts as a prebiotic, meaning they feed the helpful bacteria in your gut. They are gener...
NutraFlora scFOS monograph & interactionsOther (inactive) ingredients: Hypromellose, Microcrystalline Cellulose, Calcium Laurate, Silica. These complete the product’s ingredient list but are not active constituents.
Prebiotic by Swanson Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Prebiotic. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Prebiotic, from the product label.
Swanson
See all Swanson products- Name
- Swanson Health Products
- City
- Fargo
- State
- ND
- ZipCode
- 58104
- Phone Number
- 1-800-437-4148
- Web Address
- www.swansonvitamins.com
Prebiotic by Swanson: Common Questions
Does Prebiotic by Swanson interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What does FOS actually do?
Will this make me bloated or gassy?
Is it safe to take this while pregnant or breastfeeding?
How much should I take?
Does this product have fillers?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Prebiotic is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Prebiotic’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Prebiotic's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 6 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Fructo-oligosaccharides (fos) 6 references
- Briet F, et al. Symptomatic response to varying levels of fructo-oligosaccharides consumed occasionally or regularly. Eur J Clin Nutr 1995;49:501-7.
- Bouhnik Y, Vahedi K, Achour L, et al. Short-chain fructo-oligosaccharide administration dose-dependently increases fecal bifidobacteria in healthy humans. J Nutr 1999;129:113-6. PubMed
- Cummings JH, Macfarlane GT, Englyst HN. Prebiotic digestion and fermentation. Am J Clin Nutr 2001;73:415S-420S. PubMed
- Souza DDS, Tahan S, Weber TK, Araujo-Filho HB, de Morais MB. Randomized, double-blind, placebo-controlled parallel clinical trial assessing the effect of fructooligosaccharides in infants with constipation. Nutrients. 2018;10(11). pii: E1602. PubMed
- Andermann TM, Fouladi F, Tamburini FB, et al. A Fructo-Oligosaccharide Prebiotic Is Well Tolerated in Adults Undergoing Allogeneic Hematopoietic Stem Cell Transplantation: A Phase I Dose-Escalation Trial. Transplant Cell Ther 2021;27(11):932. PubMed
- Dou Y, Yu X, Luo Y, Chen B, Ma D, Zhu J. Effect of Fructooligosaccharides Supplementation on the Gut Microbiota in Human: A Systematic Review and Meta-Analysis. Nutrients 2022;14(16):3298. PubMed
See these in context on the Fructo-oligosaccharides (fos) monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC