Primal Probiotics Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Primal Probiotics against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Primal Probiotics is a dietary supplement by Primal Blueprint with 4 active ingredients. Its ingredients are commonly taken for digestive and gut health, source of soluble fiber, constipation or bowel regularity.Based on those ingredients, 2,080 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Acacia Gum, Probiotic Blend. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Primal Probiotics by Primal Blueprint
Ask about any prescription or over-the-counter medication and we check it for interactions with Primal Probiotics by Primal Blueprint — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Primal Probiotics by Primal Blueprint
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
This product contains 7 active ingredients: acacia gum, a prebiotic blend, a probiotic blend, fructooligosaccharides (FOS), soluble tapioca fiber, and four specific probiotic strains — Bifidobacterium lactis (Bl-04), Lactobacillus paracasei (LPC-37), Lactobacillus acidophilus (NCFM), and Bifidobacterium animalis lactis (Bl-07). The prebiotics (acacia gum, FOS, and soluble tapioca fiber) feed your existing beneficial bacteria, while the probiotics add live beneficial microorganisms to your gut.
The inactive ingredients — microcrystalline cellulose, gelatin capsule, magnesium stearate, and silicon dioxide — are fillers and the capsule itself.
Does it work?
Moderate evidence
The evidence for this product's individual ingredients is mixed. Lactobacillus acidophilus is possibly effective for irritable bowel syndrome (IBS), antibiotic-associated diarrhea, Helicobacter pylori infection, and bacterial vaginosis.
For acacia gum and fructooligosaccharides (FOS), the evidence for their intended uses — metabolic syndrome, kidney failure, obesity, and others — is insufficient to rate reliably based on the data we hold. We don't have effectiveness ratings on file for the other probiotic strains, soluble tapioca fiber, or the prebiotic and probiotic blends as whole ingredients.
How safe is it?
Well-documented data
Lactobacillus acidophilus is generally well tolerated in healthy adults and children, though you should check with your doctor before starting it. Acacia gum is recognized as safe as a food additive but can cause digestive upset at higher doses.
The most common side effects are abdominal bloating, flatulence, and mild diarrhea — these occurred in a notable number of trial participants but may subside within 2 weeks of continued use. Fructooligosaccharides (FOS) are generally well tolerated but commonly cause gas and bloating, especially at higher doses.
Rare but serious infections have been reported with L. acidophilus in immunocompromised patients, though this is uncommon. For pregnancy and lactation, the safety data for acacia gum and FOS at supplement doses is limited — talk with your doctor about whether this product is right for you during those periods.
Meds to double-check
Moderate interaction found
Before taking this product, double-check with your doctor or pharmacist if you're on antibiotics (including amoxicillin) — they can reduce how well this probiotic works and may affect how your antibiotic is absorbed. You should also review any other oral medications you're taking, since the acacia gum fiber may alter their absorption.
Altogether, these interactions span 2,081 individual medications.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This probiotic may help with specific gut issues like irritable bowel syndrome or antibiotic-associated diarrhea, especially for the L. acidophilus component. If you take antibiotics or amoxicillin, you'll need to time this product carefully to avoid reducing its effects or interfering with your medication absorption.
Gas, bloating, and mild digestive upset are common starting effects but often improve within a couple of weeks. Check with your own doctor or pharmacist before starting, especially if you're on any medications or have a weakened immune system.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 7 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 27, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Primal Probiotics, straight from the product label.
| Brand | Primal Blueprint |
|---|---|
| Barcode (UPC) | 855232007798 |
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jul 27, 2021 |
| DSLD ID | 249674 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Primal Probiotics by Primal Blueprint, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Acacia Gum | 0 NP | -- |
| Prebiotic Blend | 200 mg | -- |
| Probiotic Blend | 27 mg | -- |
| Fructooligosaccharides | 0 NP | -- |
| soluble Tapioca Fiber | 0 NP | -- |
| Bifidobacterium lactis (Bl-04) | 0 NP | -- |
| Lactobacillus paracasei (LPC-37) | 0 NP | -- |
| Lactobacillus acidophilus (NCFM) | 0 NP | -- |
| Bifidobacterium animalis lactis (Bl-07) | 0 NP | -- |
| Total Probiotic Culture | 0 NP | -- |
Other ingredients: Microcrystalline Cellulose, Gelatin Capsule, Magnesium Stearate, Silicon Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Digestive & immune support
Primal Probiotics provide a unique blend of four research-proven probiotics that support the digestive and immune systems.
FDA Statement of Identity
Dietary Supplement
Formula
4 Probiotic strains 10 Billion CFU per capsule 200 mg Prebiotics
Suggested/Recommended/Usage/Directions
Suggested Use: Take 1 capsule per day before or during meals.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Storage
Store in a cool, dry place away from direct sunlight
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Primal Probiotics by Primal Blueprint label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Primal Probiotics by Primal Blueprint
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Prebiotic Blend
- › Acacia Gum
- › Fructooligosaccharides
- › Soluble Tapioca Fiber
Probiotic Blend
Interacts with182 drugs
Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy p...
Probiotic Blend monograph & interactions- › Total Probiotic Culture
Other (inactive) ingredients: Microcrystalline Cellulose, Gelatin Capsule, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.
Primal Probiotics by Primal Blueprint Drug Interactions
HelloPharmacist Interaction Report
Primal Blueprint Primal Probiotics has documented interactions through its acacia gum and Lactobacillus acidophilus (NCFM) content.
The most serious concern is a moderate interaction with antibiotics — L. acidophilus can be killed by antibiotic drugs, which reduces the probiotic's effectiveness. You'll want to separate doses by a few hours.
Read the full breakdown — every affected drug type, severity by severity
Acacia gum moderately reduces the absorption of amoxicillin (Amoxil, Trimox) and may theoretically alter how your body takes in other oral medications due to its fiber content. To minimize this effect, take amoxicillin at least 2 hours away from this product.
More broadly, the fiber in acacia gum can change how water-insoluble drugs (like naproxen) and polar drugs (like certain antibiotics) are absorbed.
We could not check three of the probiotic strains in this product — soluble tapioca fiber, Bifidobacterium lactis (Bl-04), Lactobacillus paracasei (LPC-37), and Bifidobacterium animalis lactis (Bl-07) — so there may be additional interactions we don't have data for. Before you start taking this product with any prescription medications, use the interaction checker on this page with your exact medication list.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Primal Probiotics?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Primal Probiotics interact with 2,080 drugs. Click any drug to see the details.
2 of the 4 ingredients in Primal Probiotics interact with drugs. Each result below shows which ingredient is responsible. Acacia Gum Probiotic Blend
"phentolamineOraVerse, Rogitine, Ryzumvi
How "phentolamine interacts with Primal Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Acacia GumOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Gum + "phentolamine interaction6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Primal Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Acacia GumOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Gum + 6-mercaptopurine interactionAbacavirZiagen
How Abacavir interacts with Primal Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Acacia GumOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Gum + Abacavir interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Primal Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Acacia GumOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Gum + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Primal Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Acacia GumOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Gum + Abacavir, Lamivudine interactionAbciximabReoPro
How Abciximab interacts with Primal Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Acacia GumOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Gum + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Primal Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Acacia GumOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Gum + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Primal Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Acacia GumOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Gum + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Primal Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Acacia GumOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Gum + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Primal Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Acacia GumOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Gum + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Primal Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Acacia GumOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Gum + Acalabrutinib interactionAcamprosateCampral
How Acamprosate interacts with Primal Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Acacia GumOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Gum + Acamprosate interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Primal Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Acacia GumOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Gum + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Primal Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Acacia GumOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Gum + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Primal Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Acacia GumOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Gum + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with Primal Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Acacia GumOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Gum + Acepromazine interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Primal Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Acacia GumOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Gum + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Primal Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Acacia GumOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Gum + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Primal Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Acacia GumOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Gum + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Primal Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Acacia GumOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Gum + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Primal Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Acacia GumOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Gum + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Primal Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Acacia GumOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Gum + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Primal Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Acacia GumOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Gum + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Primal Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Acacia GumOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Gum + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Primal Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Acacia GumOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Gum + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Primal Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Acacia GumOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Gum + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Primal Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Acacia GumOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Gum + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Primal Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Acacia GumOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Gum + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Primal Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Acacia GumOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Gum + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Primal Probiotics — through 1 ingredient. Tap an ingredient for the detail:
Acacia GumOral Drugs Moderate
Interaction Summary
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Acacia Gum + Acetaminophen, Caffeine, Isometheptene interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Primal Probiotics with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Acacia Gum
Amoxicillin (Amoxil, Trimox)
Gum arabic can reduce the absorption of amoxicillin.
A small study in healthy volunteers shows that taking amoxicillin and gum arabic concurrently significantly reduces the absorption of amoxicillin. Separate doses of amoxicillin from gum arabic by at least 2 hours.
Oral Drugs
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Gum arabic has been used as a suspending osmotic agent in drug formulations. It might improve bioavailability of water-insoluble drugs like naproxen, but reduce absorption of polar drugs like amoxicillin. To avoid changes in absorption, take gum arabic 30-60 minutes after oral medications.
Probiotic Blend
Antibiotic Drugs
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.
Brand information
Manufacturer and brand details for Primal Probiotics, from the product label.
Primal Blueprint
See all Primal Blueprint products- Name
- Primal Nutrition, LLC
- City
- Oxnard
- State
- CA
- ZipCode
- 93033
- Phone Number
- 1-888-774-6259
- Web Address
- primalblueprint.com
Primal Probiotics by Primal Blueprint: Common Questions
Does Primal Probiotics by Primal Blueprint interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will this probiotic work if I'm taking antibiotics?
What side effects should I expect?
Can I take this while pregnant or breastfeeding?
What do the prebiotic ingredients do?
Does this help with IBS or diarrhea?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Primal Probiotics is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Primal Probiotics’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Gum Arabic
Interacts with 2,022 drugsGum arabic is a soluble dietary fiber from the acacia tree that is widely used as a safe food additive and is sometimes taken as a supplement for digestive health and as a prebiotic. Early s...
Read the full Gum Arabic monograph → Herb & supplement monographFructo-oligosaccharides (fos)
Fructo-oligosaccharides (FOS) are a type of soluble fiber that acts as a prebiotic, meaning they feed the helpful bacteria in your gut. They are generally considered safe for most people in...
Read the full Fructo-oligosaccharides (fos) monograph → Herb & supplement monographLactobacillus Acidophilus
Interacts with 182 drugsLactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...
Read the full Lactobacillus Acidophilus monograph →Sources & How We Checked
Primal Probiotics's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 29 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Gum Arabic 8 references
- Jensen CD, Spiller GA, Gates JE, et al. The effect of acacia gum and a water-soluble dietary fiber mixture on blood lipids in humans. J Am Coll Nutr 1993;12:147-54. PubMed
- Eltayeb IB, Awad AI, Elderbi MA, Shadad SA. Effect of gum arabic on the absorption of a single oral dose of amoxicillin in healthy Sudanese volunteers. J Antimicrob Chemother 2004;54:577-8. PubMed
- Babiker R, Merghani TH, Elmusharaf K, et al. Effects of gum Arabic ingestion on body mass index and body fat percentage in healthy adult females: two-arm randomized, placebo controlled, double-blind trial. Nutr J 2012;11:111. PubMed
- Babiker R, Elmusharaf K, Keogh MB, Banaga AS, Saeed AM. Metabolic effect of gum Arabic (Acacia senegal) in patients with type 2 diabetes mellitus (T2DM): randomized, placebo controlled double blind trial. Functional Foods in Health and Disease. 2017;7(3): DOI
- Beneke CE, Viljoen AM, Hamman JH. Polymeric plant-derived excipients in drug delivery. Molecules. 2009;14(7):2602-20. PubMed
- Ali NE, Kaddam LA, Alkarib SY, et al. Gum Arabic (Acacia Senegal) Augmented Total Antioxidant Capacity and Reduced C-Reactive Protein among Haemodialysis Patients in Phase II Trial. Int J Nephrol. 2020;2020:7214673.
- Mortensen A, Aguilar F, Crebelli R, et al. Re-evaluation of acacia gum (E 414) as a food additive. EFSA J. 2017;15(4):e04741. PubMed
- Larson R, Nelson C, Korczak R, et al. Acacia Gum Is Well Tolerated While Increasing Satiety and Lowering Peak Blood Glucose Response in Healthy Human Subjects. Nutrients 2021;13(2):618. PubMed
Lactobacillus Acidophilus 15 references
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
- Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
- Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
- Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
- Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
- Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
- Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
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See these in context on the Lactobacillus Acidophilus monograph →
Fructo-oligosaccharides (fos) 6 references
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See these in context on the Fructo-oligosaccharides (fos) monograph →
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