Interactions on record — worth a quick check against your medications. Based on 2 of 4 ingredients. Check your meds →
Dietary supplement

Pro-V Male Performance Ingredients & Drug Interactions

by King Nutrition

Pro-V Male Performance label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Pro-V Male Performance against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Pro-V Male Performance is a dietary supplement by King Nutrition with 4 active ingredients. Its ingredients are commonly taken for coughs and breathing problems, asthma and bronchitis symptoms, altitude or shortness of breath.Based on those ingredients, 208 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Carthamus tinctorius. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Pro-V Male Performance by King Nutrition

Ask about any prescription or over-the-counter medication and we check it for interactions with Pro-V Male Performance by King Nutrition — and tell you which ingredient is responsible.

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Computed from our clinical databases

HelloPharmacist Scorecard of Pro-V Male Performance by King Nutrition

Four independent checks of what is known — a summary of the available information, not a grade of the product itself.

Evidence for Intended Use
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

The stated purpose hasn't been mapped to our evidence data yet.

Why this rating?
  • We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Ingredient Transparency
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 4 active ingredients.
  • “THE BLUE CAPSULE(TM)” is listed as a grouped ingredient — the label gives one combined amount (325 mg) without saying how much of each component you get.
Known Interaction Concern
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Safflower.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 208 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Safety Information
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

HelloPharmacist summaryFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Assessment coverage: 2 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pro-V Male Performance, straight from the product label.

Brand King Nutrition
Barcode (UPC) 851330004110
Net contents 28 Cap(s)
Market status Off market
Date entered into DSLD Feb 25, 2013
DSLD ID 17007
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult Male (18-50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pro-V Male Performance by King Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
28
UPC/BARCODE
851330004110
IngredientAmount% DV
Quebracho blanco0 NP--
THE BLUE CAPSULE(TM)325 mg--
Carthamus tinctorius0 NP--
Clerodendron capitatum0 NP--
Lophira laceolata0 NP--

Other ingredients: Gelatin, Microcrystalline Cellulose, Magnesium Stearate, FD&C Blue No. 1, Titanium Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

MALE ENHANCEMENT* Unique one (1) capsule dose delivery system supports male performance enhancement.* TESTOSTERONE BOOSTER* Promotes increased free testosterone by lowering cortisol and by helping block the aromatase enzyme.* IMPROVED SENSE OF WELLNESS* Helps to promote that “look better, feel better” sense of wellness.* INCREASED LIBIDO & ENERGY* Supports enhanced sexual libido, increased energy levels and performance capability.*

“The Little Blue Capsule that Works”

Male Enhancement* Testosterone Booster* Increases Sense of Wellness* Energy & Libido*

TEST BOOSTER MALE PERFORMANCE

When combined with a proper exercise and nutrition regime. Statements based on early-stage independent 3rd party in vivo and / or in vitro model scientific research data findings.

Rev. 01-001-PRV001 05/12

Chart Shows Direct Correlation between Anti-Aromatase and Increased Testosterone Levels (Chart) COMPARATIVE ANTI-AROMATASE ACTIVITY IN A HUMAN CELL MODEL 0.43 µg/ml Anti-Aromatase Control compound 0.31 µg/ml Anti-Aromatase Activity of PRO-V(TM) Active POTENT AROMATASE INHIBITOR IC50 Values (half maximal inhibitory concentration)

FDA Statement of Identity

DIETARY SUPPLEMENT

Suggested/Recommended/Usage/Directions

Please read entire label before use.

Suggested Use: Take one (1) capsule as needed, or one (1) capsule one (1) hour prior to desired activity, or as recommended by a qualified healthcare practitioner. This product can be taken with or without food.

Precautions

KEEP OUT OF REACH OF CHILDREN.

DO NOT USE IF SAFETY SEAL IS BROKEN.

Warnings: Not intended for individuals under age of 18, unless instructed by a doctor.

Consult your physician prior to use if you have high blood pressure or heart problems or are taking prescription drugs.

Do not exceed the recommended daily intake. Seek the advice of a healthcare professional before beginning any supplement or exercise program. Improper use of this product will not improve results and is not advised.

FDA Disclaimer Statement

* THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT, CURE, OR PREVENT ANY DISEASE.

Formula

POWERFUL TESTOSTERONE BOOSTER*

Seals/Symbols

KinG NUTRITION

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Pro-V Male Performance by King Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Pro-V Male Performance label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Pro-V Male Performance by King Nutrition

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container28 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

THE BLUE CAPSULE(TM)

325 mg per serving

Other (inactive) ingredients: Gelatin, Microcrystalline Cellulose, Magnesium Stearate, FD&C Blue No. 1, Titanium Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pro-V Male Performance by King Nutrition Drug Interactions

Pro-V Male Performance contains 4 ingredients, and 1 of them has known drug interactions. Altogether it interacts with 208 medications. Here’s the picture, then you can look up your own drug.

Want to check YOUR meds against Pro-V Male Performance?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
208Drugs
208 Moderate

Ingredients driving the most interactions

Carthamus tinctorius 208

Individual Drug Interactions

The ingredients in Pro-V Male Performance interact with 208 drugs. Click any drug to see the details.

1 of the 4 ingredients in Pro-V Male Performance interact with drugs. Each result below shows which ingredient is responsible. Carthamus tinctorius

Each ingredient & the kinds of drugs it affects

For each ingredient in Pro-V Male Performance with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Carthamus tinctorius3 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

High doses of safflower oil might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Small clinical studies show that taking safflower oil, approximately 55 grams daily for 2-3 weeks, decreases platelet aggregation. However, taking lower doses of safflower oil, such as 5 grams daily for 4 weeks, does not seem to affect platelet function. In one case report, a 74-year-old male stabilized on warfarin developed urinary tract bleeding and an elevated INR after taking a safflower extract 20 grams daily for 14 days.

Likelihood Possible Evidence B
Antidiabetes Drugs

Theoretically, safflower oil might alter the effects of antidiabetes drugs.
Some clinical research shows that taking safflower oil 10 grams daily for 3 weeks can increase fasting blood glucose in patients with type 2 diabetes. However, clinical research in patients with metabolic syndrome with or without impaired glucose tolerance shows that taking safflower oil 8 grams daily for 12 weeks reduces fasting glucose levels by around 8 mg/dL. Some clinical research also shows that taking safflower oil 8 grams daily for 16 weeks does not affect fasting glucose levels in patients with type 2 diabetes.

Likelihood Possible Evidence B
Warfarin

Theoretically, safflower oil might increase the risk of bleeding when taken with warfarin.
In one case report, a 74-year-old male stabilized on warfarin developed urinary tract bleeding and an elevated INR after taking a safflower extract 20 grams daily for 14 days.

Likelihood Possible Evidence D
Carthamus tinctorius full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Pro-V Male Performance, from the product label.

King Nutrition

See all King Nutrition products
Name
KING NUTRITION
City
Fort Lauderdale
ZipCode
33301
Pharmacist Counseling Corner

Pro-V Male Performance by King Nutrition: Common Questions

Does Pro-V Male Performance by King Nutrition interact with any medications?
Yes. Based on its ingredients, Pro-V Male Performance has a known interaction with 208 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Pro-V Male Performance contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pro-V Male Performance is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pro-V Male Performance label
Go deeper

The Full Monographs Behind Pro-V Male Performance’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Quebracho Blanco

Quebracho Blanco is the bark of a South American tree traditionally used for breathing problems and coughs, but high-quality human studies are lacking. It contains alkaloids that may affect...

Read the full Quebracho Blanco monograph → Herb & supplement monograph

Safflower

Interacts with 208 drugs

Safflower is a thistle-like plant used mainly for its seed oil (a common cooking oil) and its colorful flowers. Safflower oil is a reasonable source of unsaturated fats, but strong proof tha...

Read the full Safflower monograph →
Sources

Sources & How We Checked

Pro-V Male Performance's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Quebracho Blanco 1 reference
  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

See these in context on the Quebracho Blanco monograph →

Safflower 14 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  3. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  4. Borkman M, Chisholm DJ, Furler SM, et al. Effects of fish oil supplementation on glucose and lipid metabolism in NIDDM. Diabetes 1989;38:1314-9.. PubMed
  5. Amato, P. and Quercia, R. A. A historical perspective and review of the safety of lipid emulsion in pregnancy. Nutr Clin Pract. 1991;6(5):189-192. PubMed
  6. Demke, D. M., Peters, G. R., Linet, O. I., Metzler, C. M., and Klott, K. A. Effects of a fish oil concentrate in patients with hypercholesterolemia. Atherosclerosis 1988;70(1-2):73-80. PubMed
  7. Kaji, K., Yoshida, S., Nagata, N., Yamashita, T., Mizukoshi, E., Honda, M., Kojima, Y., and Kaneko, S. An open-label study of administration of EH0202, a health-food additive, to patients with chronic hepatitis C. J Gastroenterol. 2004;39(9):873-878. PubMed
  8. Kwon, J. S., Snook, J. T., Wardlaw, G. M., and Hwang, D. H. Effects of diets high in saturated fatty acids, canola oil, or safflower oil on platelet function, thromboxane B2 formation, and fatty acid composition of platelet phospholipids. Am.J.Clin.Nutr. PubMed
  9. Lloyd-Still, J. D., Simon, S. H., Wessel, H. U., and Gibson, L. E. Negative effects of oral fatty acid supplementation on sweat chloride in cystic fibrosis. Pediatrics 1979;64(1):50-52. DOI
  10. Challen, A. D., Branch, W. J., and Cummings, J. H. The effect of aspirin and linoleic acid on platelet aggregation, platelet fatty acid composition and haemostasis in man. Hum Nutr Clin Nutr 1983;37(3):197-208.
  11. Asp ML, Collene AL, Norris LE, Cole RM, Stout MB, Tang SY, Hsu JC, Belury MA. Time-dependent effects of safflower oil to improve glycemia, inflammation and blood lipids in obese, post-menopausal women with type 2 diabetes: a randomized, double-masked, cro
  12. Liu Y, Liu S, Shi Y, et al. Effects of safflower injection on the pharmacodynamics and pharmacokinetics of warfarin in rats. Xenobiotica. 2017 Oct 25:1-6. [Epub ahead of print] PubMed
  13. de Ataide EC, Reges Perales S, de Oliveira Peres MA, et al. Acute liver failure induced by Carthamus tinctorius oil: Case reports and literature review. Transplant Proc. 2018;50(2):476-477. PubMed
  14. Ruyvaran M, Zamani A, Mohamadian A, et al. Safflower (Carthamus tinctorius L.) oil could improve abdominal obesity, blood pressure, and insulin resistance in patients with metabolic syndrome: a randomized, double-blind, placebo-controlled clinical trial. PubMed

See these in context on the Safflower monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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