Probiotic Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Probiotic against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Probiotic is a dietary supplement by Nutrition Essentials with 3 active ingredients. Its ingredients are commonly taken for constipation, irritable bowel syndrome (ibs), diarrhea.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Uni-BactCF-15, Acidophilus. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Probiotic by Nutrition Essentials
Ask about any prescription or over-the-counter medication and we check it for interactions with Probiotic by Nutrition Essentials — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Probiotic by Nutrition Essentials
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
This probiotic has 3 active ingredients: Bacillus coagulans, Lactobacillus acidophilus, and two others we need to flag. Nutri-Fructo B-88 and the Super Probiotic Blend are listed, but we couldn't pull full interaction data for the first one, and the Blend's exact strains and count aren't broken out here—you may want to check the label or contact the maker for those details.
Both Bacillus coagulans and Lactobacillus acidophilus are live-organism probiotics meant to support gut health. The tablet also contains inactive ingredients like microcrystalline cellulose, dicalcium phosphate, and stearic acid as binders and fillers.
Does it work?
Moderate evidence
Evidence for this product's benefits is mixed and depends on the ingredient. Lactobacillus acidophilus is rated Possibly Effective for irritable bowel syndrome (IBS), Helicobacter pylori infection, antibiotic-associated diarrhea, and bacterial vaginosis.
Bacillus coagulans is rated Possibly Effective for constipation and IBS. However, the evidence for antibiotic-associated diarrhea with Bacillus coagulans, as well as athletic performance, cancer, and fatty liver disease, is not yet reliable enough to rate.
Without details on the strains in the Blend or data for Nutri-Fructo B-88, we can't assess their individual roles in the formula's overall effect.
How safe is it?
Well-documented data
Both Lactobacillus acidophilus and Bacillus coagulans are generally well tolerated in healthy adults, though product quality varies and reliable safety data are limited—talk it over with your doctor before starting. Gastrointestinal side effects from Lactobacillus acidophilus are uncommon but can include bloating, flatulence, abdominal pain, and digestive upset when combined with other probiotics.
A rare but serious concern exists: since both ingredients contain live organisms, there's a theoretical risk of infection in patients with weakened immunity, central venous catheters, or severe illness; this risk is thought to be very low in people with healthy, intact immune systems. For Pregnancy and Lactation, Lactobacillus acidophilus is rated Possibly Safe in pregnancy, but no data are on file for the other ingredients—check with your doctor or pharmacist for personalized guidance.
Meds to double-check
Moderate interaction found
Hold off on taking this product at the same time as antibiotic drugs (Moderate severity). Antibiotics can kill the live organisms in the probiotic, making it ineffective.
Space them out by a few hours and run your exact medications through the checker on this page before you start.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
If you're dealing with IBS, constipation, or antibiotic-associated diarrhea and have a healthy immune system, this probiotic may be worth considering. The key is timing: keep antibiotics and this product a few hours apart so the antibiotic doesn't kill the beneficial bacteria.
Talk with your doctor or pharmacist before starting, especially if you have any chronic illness, a weakened immune system, or are pregnant or breastfeeding.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 21, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Probiotic, straight from the product label.
| Brand | Nutrition Essentials |
|---|---|
| Barcode (UPC) | X000SA9DUB |
| Net contents | 60 Tablet(s) |
| Market status | On market |
| Date entered into DSLD | Nov 21, 2020 |
| DSLD ID | 239599 |
| Product type | Other Combinations |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Probiotic by Nutrition Essentials, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Nutri-Fructo B-88 | 500 mg | -- |
| Super Probiotic Blend | 75 mg | -- |
| Uni-BactCF-15 | 0 NP | -- |
| Acidophilus | -- | -- |
Other ingredients: Microcrystalline Cellulose, Dicalcium Phosphate, Stearic Acid, Croscarmellose Sodium, Silicon Dioxide, Vegetable Magnesium Stearate, Hydroxypropyl Methylcellulose
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested Use: For adults only. Take one (1) or two (2) tablets per day on an empty stomach.
Precautions
Caution: Women who are pregnant or lactating and anyone taking medications or other dietary supplements should consult a health care professional before using any nutritional product.
If any adverse reactions occur, discontinue use and consult a health care professional.
Not for use by children under the age of 18. Keep out of the reach of children.
Do not use if safety seal is damaged or missing.
Storage
Store in a cool, dry place.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Formulation
Digestive health support formula Supports healthy digestive balance Helps replenish healthy bacteria Promotes immune system health
Seals/Symbols
GMP Followed
FDA Statement of Identity
Dietary Supplement
Brand IP Statement(s)
Uni-Bact CF-15 is a trademark of Union Biotech Sciences Nutri-Fructo B-88 is a trademark of Avexyl Pharma, LLC.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Probiotic by Nutrition Essentials label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Probiotic by Nutrition Essentials
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container60 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Nutri-Fructo B-88
Super Probiotic Blend
Other (inactive) ingredients: Microcrystalline Cellulose, Dicalcium Phosphate, Stearic Acid, Croscarmellose Sodium, Silicon Dioxide, Vegetable Magnesium Stearate, Hydroxypropyl Methylcellulose. These complete the product’s ingredient list but are not active constituents.
Probiotic by Nutrition Essentials Drug Interactions
HelloPharmacist Interaction Report
Nutrition Essentials Probiotic contains two ingredients with documented interactions: Bacillus coagulans and Lactobacillus acidophilus, both affecting antibiotics.
The most serious concern is a Moderate-severity interaction with antibiotic drugs—taking antibiotics at the same time as either ingredient may kill off the live organisms in the probiotic, making it less effective. The solution is straightforward: space out your antibiotic and this probiotic by a few hours so they don't interfere with each other.
Read the full breakdown — every affected drug type, severity by severity
Additionally, we could not check Nutri-Fructo B-88, as we hold no interaction data for it. We also don't know the specific bacterial strains in the Super Probiotic Blend component without further details.
Altogether, these interactions span 182 individual medications.
To be sure how this product fits with your specific prescriptions, use the medication checker on this page to look up each one.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Probiotic?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Probiotic interact with 182 drugs. Click any drug to see the details.
2 of the 3 ingredients in Probiotic interact with drugs. Each result below shows which ingredient is responsible. Uni-BactCF-15 Acidophilus
Dicloxacillin SodiumDycill, Dynapen, Pathocil, Pathocil Injection
How Dicloxacillin Sodium interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Acidophilus + Dicloxacillin Sodium interactionUni-bactcf-15Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Uni-bactcf-15 + Dicloxacillin Sodium interactionDirithromycinDynabac
How Dirithromycin interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Acidophilus + Dirithromycin interactionUni-bactcf-15Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Uni-bactcf-15 + Dirithromycin interactionDoripenemDoribax
How Doripenem interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Acidophilus + Doripenem interactionUni-bactcf-15Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Uni-bactcf-15 + Doripenem interactionDoxycyclineDoryx, Doxy, Doxy-D, Doxycin, Doxycycline Injection, Doxylin +6 more
How Doxycycline interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Acidophilus + Doxycycline interactionUni-bactcf-15Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Uni-bactcf-15 + Doxycycline interactionDoxycycline HyclateActiclate, Acticlate Cap, Lymepak
How Doxycycline Hyclate interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Acidophilus + Doxycycline Hyclate interactionUni-bactcf-15Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Uni-bactcf-15 + Doxycycline Hyclate interactionDoxycycline MonohydrateErfacea
How Doxycycline Monohydrate interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
Uni-bactcf-15Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Uni-bactcf-15 + Doxycycline Monohydrate interactionAcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Acidophilus + Doxycycline Monohydrate interactionDoxycylineDoxychel
How Doxycyline interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Acidophilus + Doxycyline interactionUni-bactcf-15Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Uni-bactcf-15 + Doxycyline interactionEnoxacinPenetrex
How Enoxacin interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Acidophilus + Enoxacin interactionUni-bactcf-15Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Uni-bactcf-15 + Enoxacin interactionErtapenemInvanz
How Ertapenem interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Acidophilus + Ertapenem interactionUni-bactcf-15Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Uni-bactcf-15 + Ertapenem interactionErythromycinE-Mycin, Ery-Tab, Eryc, EryPed Chewable, Erythro Base, Erythro E-C +6 more
How Erythromycin interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Acidophilus + Erythromycin interactionUni-bactcf-15Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Uni-bactcf-15 + Erythromycin interactionErythromycin EthylsuccinateE.E.S. 400, E.E.S. Chewable, Wyamycin S
How Erythromycin Ethylsuccinate interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Acidophilus + Erythromycin Ethylsuccinate interactionUni-bactcf-15Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Uni-bactcf-15 + Erythromycin Ethylsuccinate interactionErythromycin Ethylsuccinate, SulfisoxazolePediazole
How Erythromycin Ethylsuccinate, Sulfisoxazole interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Acidophilus + Erythromycin Ethylsuccinate, Sulfisoxazole interactionUni-bactcf-15Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Uni-bactcf-15 + Erythromycin Ethylsuccinate, Sulfisoxazole interactionErythromycin GluceptateErythromycin Gluceptate
How Erythromycin Gluceptate interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
Uni-bactcf-15Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Uni-bactcf-15 + Erythromycin Gluceptate interactionAcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Acidophilus + Erythromycin Gluceptate interactionErythromycin LactobionateErythromycin Lactobionate
How Erythromycin Lactobionate interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Acidophilus + Erythromycin Lactobionate interactionUni-bactcf-15Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Uni-bactcf-15 + Erythromycin Lactobionate interactionErythromycin StearateErythro-S, Erythrocin, Ethril
How Erythromycin Stearate interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Acidophilus + Erythromycin Stearate interactionUni-bactcf-15Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Uni-bactcf-15 + Erythromycin Stearate interactionErythromycin, SulfisoxazoleEryzole
How Erythromycin, Sulfisoxazole interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Acidophilus + Erythromycin, Sulfisoxazole interactionUni-bactcf-15Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Uni-bactcf-15 + Erythromycin, Sulfisoxazole interactionFidaxomicinDificid
How Fidaxomicin interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
Uni-bactcf-15Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Uni-bactcf-15 + Fidaxomicin interactionAcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Acidophilus + Fidaxomicin interactionFinafloxacinXtoro
How Finafloxacin interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Acidophilus + Finafloxacin interactionUni-bactcf-15Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Uni-bactcf-15 + Finafloxacin interactionFlucloxacillinStaphylex
How Flucloxacillin interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
Uni-bactcf-15Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Uni-bactcf-15 + Flucloxacillin interactionAcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Acidophilus + Flucloxacillin interactionFosfomycinMonurol
How Fosfomycin interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Acidophilus + Fosfomycin interactionUni-bactcf-15Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Uni-bactcf-15 + Fosfomycin interactionFurazolidoneFuroxone
How Furazolidone interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Acidophilus + Furazolidone interactionUni-bactcf-15Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Uni-bactcf-15 + Furazolidone interactionGatifloxacinTequin, Tequin Injection
How Gatifloxacin interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Acidophilus + Gatifloxacin interactionUni-bactcf-15Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Uni-bactcf-15 + Gatifloxacin interactionGemifloxacinFactive
How Gemifloxacin interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Acidophilus + Gemifloxacin interactionUni-bactcf-15Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Uni-bactcf-15 + Gemifloxacin interactionGentamicin (iv)Garamycin
How Gentamicin (iv) interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
Uni-bactcf-15Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Uni-bactcf-15 + Gentamicin (iv) interactionAcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Acidophilus + Gentamicin (iv) interactionGrepafloxacinRaxar
How Grepafloxacin interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Acidophilus + Grepafloxacin interactionUni-bactcf-15Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Uni-bactcf-15 + Grepafloxacin interactionImipenem, CilastatinPrimaxin
How Imipenem, Cilastatin interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Acidophilus + Imipenem, Cilastatin interactionUni-bactcf-15Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Uni-bactcf-15 + Imipenem, Cilastatin interactionImipenem, Cilastatin, RelebactamRecarbrio
How Imipenem, Cilastatin, Relebactam interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
Uni-bactcf-15Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Uni-bactcf-15 + Imipenem, Cilastatin, Relebactam interactionAcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Acidophilus + Imipenem, Cilastatin, Relebactam interactionIsoniazid, RifampinRifamate
How Isoniazid, Rifampin interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Acidophilus + Isoniazid, Rifampin interactionUni-bactcf-15Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Uni-bactcf-15 + Isoniazid, Rifampin interactionKanamycinKantrex
How Kanamycin interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Acidophilus + Kanamycin interactionUni-bactcf-15Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Uni-bactcf-15 + Kanamycin interactionLansoprazole, Amoxicillin, ClarithromycinPrevpac
How Lansoprazole, Amoxicillin, Clarithromycin interacts with Probiotic — through 2 ingredients. Tap an ingredient for the detail:
AcidophilusAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Acidophilus + Lansoprazole, Amoxicillin, Clarithromycin interactionUni-bactcf-15Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Uni-bactcf-15 + Lansoprazole, Amoxicillin, Clarithromycin interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Probiotic with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Uni-BactCF-15
Antibiotic Drugs
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B. coagulans.
B. coagulans preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. coagulans preparations by at least two hours.
Acidophilus
Antibiotic Drugs
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.
Brand information
Manufacturer and brand details for Probiotic, from the product label.
Nutrition Essentials
See all Nutrition Essentials products- Name
- Boost Marketing Group LLC
- Street Address
- PO Box 998
- City
- Ada
- State
- MI
- ZipCode
- 49301
- Phone Number
- 616-421-3093
Probiotic by Nutrition Essentials: Common Questions
Does Probiotic by Nutrition Essentials interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this probiotic while I'm on antibiotics?
Is this safe during pregnancy?
Can this help with antibiotic-associated diarrhea?
What side effects should I watch for?
Is this product tested and regulated?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Probiotic is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Probiotic’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Bacillus Coagulans
Interacts with 182 drugsBacillus coagulans is a spore-forming probiotic that survives stomach acid well and may help with some digestive problems such as IBS, constipation, and certain types of diarrhea. The eviden...
Read the full Bacillus Coagulans monograph → Herb & supplement monographLactobacillus Acidophilus
Interacts with 182 drugsLactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...
Read the full Lactobacillus Acidophilus monograph →Sources & How We Checked
Probiotic's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 35 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Bacillus Coagulans 20 references
- Saxelin M, Chuang NH, Chassy B, et al. Lactobacilli and bacteremia in southern Finland 1989-1992. Clin Infect Dis 1996;22:564-6. PubMed
- Tynkkynen S, Singh KV, Varmanen P. Vancomycin resistance factor of Lactobacillus rhamnosus GG in relation to enterococcal vancomycin resistance (van) genes. Int J Food Microbiol 1998;41:195-204. PubMed
- Klein G, Zill E, Schindler R, et al. Peritonitis associated with vancomycin-resistant Lactobacillus rhamnosus in a continuous ambulatory peritoneal dialysis patient; organism identification, antibiotic therapy, and case report. J Clin Microbiol 1998;36:
- Kalima P, Masterton RG, Roddie PH, et al. Lactobacillus rhamnosus infection in a child following bone marrow transplant. J Infect 1996;32:165-7. PubMed
- Goldin BR. Health Benefits of probiotics. Br J Nutr 1998;80:S203-7. DOI
- Rautio M, Jousimies-Somer H, Kauma H, et al. Liver abscess due to Lactobacillus rhamnosus strain indistinguishable from L. rhamnosus strain GG. Clin Infect Dis 1999;28:1159-60.
- MacGregor G, Smith AJ, Thakker B, Kinsella J. Yoghurt biotherapy: contraindicated in immunosuppressed patients? Postgrad Med J 2002;78:366-7. PubMed
- Land MH, Rouster-Stevens K, Woods CR, et al. Lactobacillus sepsis associated with probiotic therapy. Pediatrics 2005;115:178-81.
- De Groote MA, Frank DN, Dowell E, et al. Lactobacillus rhamnosus GG bacteremia associated with probiotic use in a child with short gut syndrome. Pediatr Infect Dis J 2005;24:278-80. PubMed
- Vahabnezhad E, Mochon AB, Wozniak LJ, Ziring DA. Lactobacillus bacteremia associated with probiotic use in a pediatric patient with ulcerative colitis. J Clin Gastroenterol. 2013;47(5):437-9. PubMed
- Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
- Sendil S, Shrimanker I, Mansoora Q, Goldman J, Nookala VK. Lactobacillus rhamnosus bacteremia in an immunocompromised renal transplant patient. Cureus. 2020;12(2):e6887. PubMed
- Albarillo FS, Shah U, Joyce C, Slade D. Lactobacillus rhamnosus Infection: A single-center 4-year descriptive analysis. J Glob Infect Dis. 2020;12(3):119-123. PubMed
- Pasala S, Singer L, Arshad T, Roach K. Lactobacillus endocarditis in a healthy patient with probiotic use. IDCases. 2020;22:e00915. PubMed
- Agrawal S, Tuchman ES, Bruce MJ, Theodorou ME. Fatal Lactobacillus endocarditis in a patient with transcatheter aortic valve replacement. BMJ Case Rep. 2020;13(11):e236835.
- Antoun M, Hattab Y, Akhrass FA, Hamilton LD. Uncommon pathogen, Lactobacillus, causing infective endocarditis: Case report and review. Case Rep Infect Dis. 2020;2020:8833948. PubMed
- Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
- Franko B, Vaillant M, Recule C, Vautrin E, et al. Lactobacillus paracasei endocarditis in a consumer of probiotics. Med Mal Infect. 2013;43(4):171-3. PubMed
- Campbell RE, Miller A, Afroze A. Native valve endocarditis secondary to Lactobacillus paracasei bacteremia. Consultant. 2020;60(9):27-8. DOI
- Kato K, Funabashi N, Takaoka H, et al. Lactobacillus paracasei endocarditis in a consumer of probiotics with advanced and severe bicuspid aortic valve stenosis complicated with diffuse left ventricular mid-layer fibrosis. Int J Cardiol. 2016;224:157-161. PubMed
Lactobacillus Acidophilus 15 references
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
- Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
- Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
- Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
- Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
- Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
- Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
- Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
- Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
- Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
- Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
- Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
- Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
- Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.
See these in context on the Lactobacillus Acidophilus monograph →
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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