Probiotic + Prebiotic Fiber Ingredients & Drug Interactions
by Swanson
What is this page for?
First and foremost: checking Probiotic + Prebiotic Fiber against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Probiotic + Prebiotic Fiber is a dietary supplement by Swanson with 2 active ingredients. Its ingredients are commonly taken for digestive and gut health, prebiotic to support good bacteria, constipation relief.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Probiotic + Prebiotic Fiber by Swanson
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Partial disclosure
This product has 2 active ingredients working together: a prebiotic fiber (NutraFlora scFOS) and a probiotic strain (Bifidobacterium lactis). The prebiotic acts as food for beneficial bacteria in your gut, while the probiotic delivers live microorganisms that may support digestive health.
The capsule also contains inactive ingredients — a cellulose-based capsule material, microcrystalline cellulose, magnesium stearate, and silica — which are standard binding and flow agents.
Does it work?
Not established
The evidence for FOS in the conditions it's studied for — osteoporosis, constipation, blood sugar control, traveler's diarrhea, and high cholesterol — is insufficient to rate. That means we don't have strong reliable data showing it works for these uses, though research is ongoing.
For Bifidobacterium lactis, effectiveness data isn't on file in our monographs. If you're considering this product for a specific health goal, ask your pharmacist what the current research shows for your situation.
How safe is it?
Well-documented data
FOS is generally well tolerated in typical food amounts, but at higher supplement doses it commonly causes gas, bloating, abdominal pain, and flatulence — especially early on. The good news: a review of clinical studies found that doses up to 15 grams daily for up to 8 weeks didn't increase these side effects more than placebo.
Start low and let your gut adjust. We don't have enough safety data on supplement-level doses to be fully confident, so check with your doctor if you have digestive concerns or are new to prebiotic fiber.
No pregnancy or lactation safety data is on file for either ingredient, so talk with your doctor or pharmacist for personalized advice if you're pregnant or nursing.
Meds to double-check
No known interactions
No interactions are documented for the ingredients we could check in this product.
The bottom line
Scorecard at a glancePartially disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.
This is a straightforward probiotic-plus-prebiotic combo with no documented drug interactions. It's worth trying if you want to support gut health, but keep in mind the effectiveness evidence is still developing.
Start with a low dose to let your digestive system adjust and watch for bloating or gas. Talk to your pharmacist if you have active digestive problems or are taking any medications.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 28, 2019.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Probiotic + Prebiotic Fiber, straight from the product label.
| Brand | Swanson |
|---|---|
| Barcode (UPC) | 087614190389 |
| Net contents | 60 Veggie Cap(s) |
| Market status | On market |
| Date entered into DSLD | May 28, 2019 |
| DSLD ID | 203230 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Probiotic + Prebiotic Fiber by Swanson, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| NutraFlora scFOS | 1 Gram(s) | -- |
| Bifidobacterium lactis | 0 NP | -- |
Other ingredients: Hydroxypropyl Methylcellulose, Microcrystalline Cellulose, Magnesium Stearate, Silica
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Supporting digestive health by encouraging the growth of friendly bacteria Supports bowel regularity Helps maintain gastrointestinal balance Science-Backed Quality Since 1969
Digestive health 500 million CFU per capsule
Suggested/Recommended/Usage/Directions
Suggested use: As a dietary supplement, take two veggie capsules per day with water.
Brand IP Statement(s)
NutraFlora and scFOS are registered trademarks of the Ingredion group of companies.
Precautions
Warning: For adults only.
Consult your physician before using this or any product if you are pregnant or nursing, taking medication or have a medical condition.
Keep out of reach of children.
Do not use if seal is broken.
Storage
Store in a cool, dry place.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Formula
500 mg FOS
FDA Statement of Identity
Dietary Supplement
General
SWA038 Rev 2 10 01 18
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Probiotic + Prebiotic Fiber by Swanson label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Probiotic + Prebiotic Fiber by Swanson
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Veggie Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
NutraFlora scFOS
No knowninteractions
Fructo-oligosaccharides (FOS) are a type of soluble fiber that acts as a prebiotic, meaning they feed the helpful bacteria in your gut. They are gener...
NutraFlora scFOS monograph & interactionsBifidobacterium lactis
Other (inactive) ingredients: Hydroxypropyl Methylcellulose, Microcrystalline Cellulose, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.
Probiotic + Prebiotic Fiber by Swanson Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Probiotic + Prebiotic Fiber. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Probiotic + Prebiotic Fiber, from the product label.
Swanson
See all Swanson products- Name
- Swanson Health Products
- City
- Fargo
- State
- ND
- ZipCode
- 58104
- Phone Number
- 1-800-437-4148
- Web Address
- swanson.com
Probiotic + Prebiotic Fiber by Swanson: Common Questions
Does Probiotic + Prebiotic Fiber by Swanson interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will this give me gas or bloating?
Can I take this if I'm pregnant or breastfeeding?
Does this actually help with digestion or gut health?
What's the difference between the probiotic and the prebiotic in this product?
Are there any fillers or weird stuff in this?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Probiotic + Prebiotic Fiber is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Probiotic + Prebiotic Fiber’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Probiotic + Prebiotic Fiber's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 6 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Fructo-oligosaccharides (fos) 6 references
- Briet F, et al. Symptomatic response to varying levels of fructo-oligosaccharides consumed occasionally or regularly. Eur J Clin Nutr 1995;49:501-7.
- Bouhnik Y, Vahedi K, Achour L, et al. Short-chain fructo-oligosaccharide administration dose-dependently increases fecal bifidobacteria in healthy humans. J Nutr 1999;129:113-6. PubMed
- Cummings JH, Macfarlane GT, Englyst HN. Prebiotic digestion and fermentation. Am J Clin Nutr 2001;73:415S-420S. PubMed
- Souza DDS, Tahan S, Weber TK, Araujo-Filho HB, de Morais MB. Randomized, double-blind, placebo-controlled parallel clinical trial assessing the effect of fructooligosaccharides in infants with constipation. Nutrients. 2018;10(11). pii: E1602. PubMed
- Andermann TM, Fouladi F, Tamburini FB, et al. A Fructo-Oligosaccharide Prebiotic Is Well Tolerated in Adults Undergoing Allogeneic Hematopoietic Stem Cell Transplantation: A Phase I Dose-Escalation Trial. Transplant Cell Ther 2021;27(11):932. PubMed
- Dou Y, Yu X, Luo Y, Chen B, Ma D, Zhu J. Effect of Fructooligosaccharides Supplementation on the Gut Microbiota in Human: A Systematic Review and Meta-Analysis. Nutrients 2022;14(16):3298. PubMed
See these in context on the Fructo-oligosaccharides (fos) monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC