Prostate Health Ingredients & Drug Interactions
by Herb Pharm
What is this page for?
First and foremost: checking Prostate Health against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Prostate Health is a dietary supplement by Herb Pharm with 5 active ingredients. Its ingredients are commonly taken for benign prostatic hyperplasia (bph) symptoms, urinary problems, hair loss.Based on those ingredients, 879 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Thuja, Saw Palmetto, Stinging Nettle. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Prostate Health by Herb Pharm
Ask about any prescription or over-the-counter medication and we check it for interactions with Prostate Health by Herb Pharm — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
Ask the Pharmacist
A licensed pharmacist will answer your question by email — free, usually within 24 hours.
Got it — thank you!
A licensed pharmacist will answer within 24 hours. Keep an eye on your email (worth checking spam, just in case).
HelloPharmacist Scorecard of Prostate Health by Herb Pharm
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Prostate Health contains five active ingredients in a liquid herbal extract blend. Saw palmetto, stinging nettle, pipsissewa, cleavers, and thuja are combined here; the exact amounts aren't detailed on the label.
The liquid also holds certified organic alcohol, distilled water, and vegetable glycerin as inactive ingredients to create the extract base.
Does it work?
Leans against
Saw palmetto is rated possibly ineffective for benign prostatic hyperplasia (BPH) — the condition most often associated with prostate supplements — and possibly effective for transurethral resection of the prostate (TURP). For other uses listed on saw palmetto's monograph, evidence is insufficient to rate.
Stinging nettle is rated possibly effective for diabetes and insufficient for other conditions in our data. Pipsissewa and thuja have no effectiveness ratings on file, and we hold no effectiveness data for cleavers.
How safe is it?
Well-documented data
Saw palmetto is generally well tolerated; the most common side effects are mild and reversible — abdominal pain, constipation, diarrhea, nausea, dizziness, fatigue, headache, and others. Stinging nettle is also generally well tolerated orally, with constipation and diarrhea being most common.
Thuja contains thujone, a neurotoxin that can cause headache, nervous agitation, seizures, gastric upset, and vomiting in large doses. Pipsissewa may cause hydroquinone toxicity with chronic use, producing tinnitus, vomiting, delirium, and convulsions.
The safety data advises against use of saw palmetto, stinging nettle, pipsissewa, and thuja during pregnancy. The same holds for breastfeeding; safety has not been established for any of these ingredients while nursing.
Meds to double-check
Moderate interaction found
Before taking Prostate Health, double-check if you use blood thinners or antiplatelet drugs (Moderate risk), birth control or estrogen therapy (Moderate), diabetes medications (Moderate), diuretics (Moderate), lithium (Moderate), seizure-threshold-lowering drugs (Moderate), immunosuppressants (Moderate), or anticonvulsants (Moderate). These are the medication types our data shows can interact with the ingredients in this product.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with graded evidence leaning against its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product is marketed for prostate health, but the evidence for its main ingredient — saw palmetto — is weak. If you take blood thinners, birth control, diabetes or seizure medications, diuretics, lithium, or immunosuppressants, check with us before starting.
Pregnancy and breastfeeding are contraindications for all the active ingredients here. Talk to your pharmacist about whether this supplement fits your health goals and medications.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 4 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2015.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Prostate Health, straight from the product label.
| Brand | Herb Pharm |
|---|---|
| Barcode (UPC) | 090700014476 |
| Net contents | 2 fl. Oz.; 60 mL |
| Market status | On market |
| Date entered into DSLD | Jun 25, 2015 |
| DSLD ID | 46725 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult Male (18-50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Prostate Health by Herb Pharm, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Extract Blend | 648 mg | -- |
| Saw Palmetto | 0 NP | -- |
| Stinging Nettle | 0 NP | -- |
| Pipsissewa | 0 NP | -- |
| Cleavers | 0 NP | -- |
| Thuja | 0 NP | -- |
Other ingredients: certified organic Alcohol, distilled Water, Vegetable Glycerin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
SUGGESTED USE Shake Well Before Using Add one full squeeze of the dropper bulb to 2 oz. of water or juice, two to four times per day. Best taken between meals.
Precautions
Caution: Not for long-term use.
Not for use in pregnant women.
Keep Out of the Reach of Children
Storage
Store away from heat & light
General
017
General Statements
SYSTEM RESTORATION Reproductive
All of the herbs in this formula are individually extracted to endure a broad spectrum of therapeutic plant compounds.
FDA Statement of Identity
HERBAL SUPPLEMENT
Brand IP Statement(s)
Prostate Health(TM)
Formula
Supports Healthy Prostate Function in Men
Formulation
GLUTEN-FREE
FDA Disclaimer Statement
THIS STATEMENT HAS NOT BEEN EVALUATED BY THE FDA. THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT, CURE OR PREVENT ANY DISEASE.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Prostate Health by Herb Pharm label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Prostate Health by Herb Pharm
These are the 5 active ingredients this product is made of. Select any to open its full monograph.
Serving size0.7 mL Dosage formLiquid Servings per container84 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Extract Blend
- › Saw Palmetto
- › Stinging Nettle
- › Pipsissewa
- › Cleavers
- › Thuja
Other (inactive) ingredients: Certified organic Alcohol, Distilled Water, Vegetable Glycerin. These complete the product’s ingredient list but are not active constituents.
Prostate Health by Herb Pharm Drug Interactions
HelloPharmacist Interaction Report
Prostate Health by Herb Pharm does interact with a number of medications.
The most serious concern is saw palmetto, one of its five active ingredients, which may increase bleeding risk when combined with blood thinners or antiplatelet drugs (like warfarin or aspirin) — a Moderate severity interaction.
Read the full breakdown — every affected drug type, severity by severity
Saw palmetto also has Moderate interactions with estrogens and birth control pills; it may reduce how well these work. Stinging nettle, another active ingredient, carries Moderate interactions with diabetes medications, diuretics, lithium, and warfarin.
Thuja, the fifth active ingredient, has Moderate interactions with seizure-threshold-lowering drugs, immunosuppressants, and anticonvulsants.
One ingredient — cleavers — we could not check because we hold no data for it. Altogether, these interactions span 873 individual medications.
Before you start this product, run your exact prescriptions through the medication checker on this page.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Prostate Health?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Prostate Health interact with 879 drugs. Click any drug to see the details.
3 of the 5 ingredients in Prostate Health interact with drugs. Each result below shows which ingredient is responsible. Thuja Saw Palmetto Stinging Nettle
Acetaminophen, CodeineTylenol No.3, Tylenol w/ Codeine
How Acetaminophen, Codeine interacts with Prostate Health — through 1 ingredient. Tap an ingredient for the detail:
ThujaSeizure Threshold Lowering Drugs Moderate
Interaction Summary
Thuja products can contains significant amounts of thujone, a neurotoxin.
Read the full Thuja + Acetaminophen, Codeine interactionAcetaminophen, Codeine, DoxylamineMersyndol
How Acetaminophen, Codeine, Doxylamine interacts with Prostate Health — through 1 ingredient. Tap an ingredient for the detail:
ThujaSeizure Threshold Lowering Drugs Moderate
Interaction Summary
Thuja products can contains significant amounts of thujone, a neurotoxin.
Read the full Thuja + Acetaminophen, Codeine, Doxylamine interactionAcetaminophen, Codeine, MethocarbamolAcetaminophen, Codeine, Methocarbamol, Robaxacet 8
How Acetaminophen, Codeine, Methocarbamol interacts with Prostate Health — through 1 ingredient. Tap an ingredient for the detail:
ThujaSeizure Threshold Lowering Drugs Moderate
Interaction Summary
Thuja products can contains significant amounts of thujone, a neurotoxin.
Read the full Thuja + Acetaminophen, Codeine, Methocarbamol interactionAcetaminophen, Dexbrompheniramine, PseudoephedrineSinadrin Plus
How Acetaminophen, Dexbrompheniramine, Pseudoephedrine interacts with Prostate Health — through 1 ingredient. Tap an ingredient for the detail:
ThujaSeizure Threshold Lowering Drugs Moderate
Interaction Summary
Thuja products can contains significant amounts of thujone, a neurotoxin.
Read the full Thuja + Acetaminophen, Dexbrompheniramine, Pseudoephedrine interactionAcetaminophen, Dextromethorphan, Doxylamine, PseudoephedrineVicks NyQuil
How Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interacts with Prostate Health — through 1 ingredient. Tap an ingredient for the detail:
ThujaSeizure Threshold Lowering Drugs Moderate
Interaction Summary
Thuja products can contains significant amounts of thujone, a neurotoxin.
Read the full Thuja + Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interactionAcetaminophen, DiphenhydramineTylenol PM, Tylenol PM Ex Strength
How Acetaminophen, Diphenhydramine interacts with Prostate Health — through 1 ingredient. Tap an ingredient for the detail:
ThujaSeizure Threshold Lowering Drugs Moderate
Interaction Summary
Thuja products can contains significant amounts of thujone, a neurotoxin.
Read the full Thuja + Acetaminophen, Diphenhydramine interactionAcetaminophen, Diphenhydramine, PseudoephedrineChildren's Tylenol Allergy, Cold Control, Contac Night Allergy Relief
How Acetaminophen, Diphenhydramine, Pseudoephedrine interacts with Prostate Health — through 1 ingredient. Tap an ingredient for the detail:
ThujaSeizure Threshold Lowering Drugs Moderate
Interaction Summary
Thuja products can contains significant amounts of thujone, a neurotoxin.
Read the full Thuja + Acetaminophen, Diphenhydramine, Pseudoephedrine interactionAcetaminophen, Doxylamine, PseudoephedrineEx Strength Tylenol Sinus Nighttime
How Acetaminophen, Doxylamine, Pseudoephedrine interacts with Prostate Health — through 1 ingredient. Tap an ingredient for the detail:
ThujaSeizure Threshold Lowering Drugs Moderate
Interaction Summary
Thuja products can contains significant amounts of thujone, a neurotoxin.
Read the full Thuja + Acetaminophen, Doxylamine, Pseudoephedrine interactionAcetaminophen, HydrocodoneAnexsia, Anodynos DHC, Azdone, Co-Gesic, Doucet, Lorcet +9 more
How Acetaminophen, Hydrocodone interacts with Prostate Health — through 1 ingredient. Tap an ingredient for the detail:
ThujaSeizure Threshold Lowering Drugs Moderate
Interaction Summary
Thuja products can contains significant amounts of thujone, a neurotoxin.
Read the full Thuja + Acetaminophen, Hydrocodone interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Prostate Health — through 1 ingredient. Tap an ingredient for the detail:
Saw PalmettoAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto + Acetaminophen, Ibuprofen interactionAcetaminophen, MeperidineDemerol APAP
How Acetaminophen, Meperidine interacts with Prostate Health — through 1 ingredient. Tap an ingredient for the detail:
ThujaSeizure Threshold Lowering Drugs Moderate
Interaction Summary
Thuja products can contains significant amounts of thujone, a neurotoxin.
Read the full Thuja + Acetaminophen, Meperidine interactionAcetaminophen, OxycodonePercocet, Roxicet, Tylox, Xartemis XR
How Acetaminophen, Oxycodone interacts with Prostate Health — through 1 ingredient. Tap an ingredient for the detail:
ThujaSeizure Threshold Lowering Drugs Moderate
Interaction Summary
Thuja products can contains significant amounts of thujone, a neurotoxin.
Read the full Thuja + Acetaminophen, Oxycodone interactionAcetaminophen, Pamabrom, PyrilamineMidol Max Strength PMS, Pamprin, Pamprin ES
How Acetaminophen, Pamabrom, Pyrilamine interacts with Prostate Health — through 1 ingredient. Tap an ingredient for the detail:
Stinging NettleDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Stinging Nettle + Acetaminophen, Pamabrom, Pyrilamine interactionAcetaminophen, PentazocineTalacen
How Acetaminophen, Pentazocine interacts with Prostate Health — through 1 ingredient. Tap an ingredient for the detail:
ThujaSeizure Threshold Lowering Drugs Moderate
Interaction Summary
Thuja products can contains significant amounts of thujone, a neurotoxin.
Read the full Thuja + Acetaminophen, Pentazocine interactionAcetaminophen, PropoxypheneDarvocet-N 100, Darvocet-N 50, E-Lor, Wygesic
How Acetaminophen, Propoxyphene interacts with Prostate Health — through 1 ingredient. Tap an ingredient for the detail:
ThujaSeizure Threshold Lowering Drugs Moderate
Interaction Summary
Thuja products can contains significant amounts of thujone, a neurotoxin.
Read the full Thuja + Acetaminophen, Propoxyphene interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Prostate Health — through 2 ingredients. Tap an ingredient for the detail:
ThujaAnticonvulsants Moderate
Interaction Summary
Thuja products can contain thujone, which might lower the seizure threshold.
Read the full Thuja + Acetazolamide interactionStinging NettleDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full Stinging Nettle + Acetazolamide interactionAcetohexamideDymelor
How Acetohexamide interacts with Prostate Health — through 1 ingredient. Tap an ingredient for the detail:
Stinging NettleAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Read the full Stinging Nettle + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Prostate Health — through 1 ingredient. Tap an ingredient for the detail:
Saw PalmettoAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Saw Palmetto + Acetylsalicylic Acid interactionAcyclovirAvaclyr, Sitavig, Zovirax, Zovirax Injection
How Acyclovir interacts with Prostate Health — through 1 ingredient. Tap an ingredient for the detail:
ThujaSeizure Threshold Lowering Drugs Moderate
Interaction Summary
Thuja products can contains significant amounts of thujone, a neurotoxin.
Read the full Thuja + Acyclovir interactionAdalimumabHumira
How Adalimumab interacts with Prostate Health — through 1 ingredient. Tap an ingredient for the detail:
ThujaImmunosuppressants Moderate
Interaction Summary
Thuja might stimulate immune function.
Read the full Thuja + Adalimumab interactionAdalimumab-adazHyrimoz
How Adalimumab-adaz interacts with Prostate Health — through 1 ingredient. Tap an ingredient for the detail:
ThujaImmunosuppressants Moderate
Interaction Summary
Thuja might stimulate immune function.
Read the full Thuja + Adalimumab-adaz interactionAdalimumab-adbmCyltezo
How Adalimumab-adbm interacts with Prostate Health — through 1 ingredient. Tap an ingredient for the detail:
ThujaImmunosuppressants Moderate
Interaction Summary
Thuja might stimulate immune function.
Read the full Thuja + Adalimumab-adbm interactionAdalimumab-afzbAbrilada
How Adalimumab-afzb interacts with Prostate Health — through 1 ingredient. Tap an ingredient for the detail:
ThujaImmunosuppressants Moderate
Interaction Summary
Thuja might stimulate immune function.
Read the full Thuja + Adalimumab-afzb interactionAdalimumab-attoAmjevita
How Adalimumab-atto interacts with Prostate Health — through 1 ingredient. Tap an ingredient for the detail:
ThujaImmunosuppressants Moderate
Interaction Summary
Thuja might stimulate immune function.
Read the full Thuja + Adalimumab-atto interactionAdalimumab-bwwdHadlima
How Adalimumab-bwwd interacts with Prostate Health — through 1 ingredient. Tap an ingredient for the detail:
ThujaImmunosuppressants Moderate
Interaction Summary
Thuja might stimulate immune function.
Read the full Thuja + Adalimumab-bwwd interactionAdalimumab-fkjpHulio
How Adalimumab-fkjp interacts with Prostate Health — through 1 ingredient. Tap an ingredient for the detail:
ThujaImmunosuppressants Moderate
Interaction Summary
Thuja might stimulate immune function.
Read the full Thuja + Adalimumab-fkjp interactionAlbiglutideTanzeum
How Albiglutide interacts with Prostate Health — through 1 ingredient. Tap an ingredient for the detail:
Stinging NettleAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Read the full Stinging Nettle + Albiglutide interactionAlefaceptAmevive
How Alefacept interacts with Prostate Health — through 1 ingredient. Tap an ingredient for the detail:
ThujaImmunosuppressants Moderate
Interaction Summary
Thuja might stimulate immune function.
Read the full Thuja + Alefacept interactionAlemtuzumabCampath
How Alemtuzumab interacts with Prostate Health — through 1 ingredient. Tap an ingredient for the detail:
ThujaImmunosuppressants Moderate
Interaction Summary
Thuja might stimulate immune function.
Read the full Thuja + Alemtuzumab interactionAlfentanilAlfenta
How Alfentanil interacts with Prostate Health — through 1 ingredient. Tap an ingredient for the detail:
ThujaSeizure Threshold Lowering Drugs Moderate
Interaction Summary
Thuja products can contains significant amounts of thujone, a neurotoxin.
Read the full Thuja + Alfentanil interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Prostate Health with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Thuja
Anticonvulsants
Thuja products can contain thujone, which might lower the seizure threshold. Theoretically, this could decrease the effectiveness of anticonvulsants drugs.
Immunosuppressants
Thuja might stimulate immune function. Theoretically, taking thuja might decrease the effects of immunosuppressive therapy. Immunosuppressant drugs include azathioprine (Imuran), basiliximab (Simulect), cyclosporine (Neoral, Sandimmune), daclizumab (Zenapax), muromonab-CD3 (OKT3, Orthoclone OKT3), mycophenolate (CellCept), tacrolimus (FK506, Prograf), sirolimus (Rapamune), prednisone (Deltasone, Orasone), and other corticosteroids (glucocorticoids).
Seizure Threshold Lowering Drugs
Thuja products can contains significant amounts of thujone, a neurotoxin. Theoretically, patients taking drugs that lower the seizure threshold might be at greater risk of seizure if they also take thuja. Advise patients taking these drugs to avoid thuja products. Some drugs that lower the seizure threshold include anesthetics (propofol, others), antiarrhythmics (mexiletine), antibiotics (amphotericin, penicillin, cephalosporins, imipenem), antidepressants (bupropion, others), antihistamines (cyproheptadine, others), immunosuppressants (cyclosporine), narcotics (fentanyl, others), stimulants (methylphenidate), theophylline, and others.
Saw Palmetto
Anticoagulant/Antiplatelet Drugs
Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Saw palmetto is reported to prolong bleeding time. Theoretically, it might increase the risk of bleeding when used concomitantly with anticoagulant or antiplatelet drugs.
Contraceptive Drugs
Saw palmetto might reduce the effectiveness of contraceptive drugs.
Saw palmetto might have antiestrogenic effects. Theoretically, it might interfere with contraceptive drugs taken concomitantly.
Estrogens
Saw palmetto might reduce the effectiveness of estrogens.
Saw palmetto might have antiestrogenic effects. Theoretically, it might interfere with estrogens taken concomitantly.
Stinging Nettle
Antidiabetes Drugs
Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Clinical research shows that stinging nettle might decrease blood glucose levels in patients with diabetes.
Diuretic Drugs
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Animal research suggests that the above ground parts and roots of stinging nettle may have a diuretic effect.
Lithium
Theoretically, stinging nettle might reduce excretion and increase levels of lithium.
Animal research suggests that stinging nettle has diuretic and natriuretic properties, which could alter the excretion of lithium. The dose of lithium might need to be decreased.
Warfarin (Coumadin)
There is some concern that stinging nettle might decrease the effects of anticoagulant drugs such as warfarin.
Stinging nettle contains a significant amount of vitamin K. When taken in large quantities, this might interfere with the activity of warfarin.
Brand information
Manufacturer and brand details for Prostate Health, from the product label.
Herb Pharm
See all Herb Pharm products- Name
- Herb Pharm
- City
- Williams
- State
- OR
- ZipCode
- 97544
- Phone Number
- 800-348-4372
- Web Address
- www.herb-pharm.com
Prostate Health by Herb Pharm: Common Questions
Does Prostate Health by Herb Pharm interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm pregnant or breastfeeding?
What are the side effects I should watch for?
Does this actually work for an enlarged prostate?
Why is there alcohol in a liquid herbal product?
What is saw palmetto supposed to do?
Can I take this with my blood thinner?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Prostate Health is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Prostate Health’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Saw Palmetto
Interacts with 174 drugsSaw palmetto is a plant extract most often used for urinary symptoms linked to an enlarged prostate (BPH). The best research suggests it works no better than a placebo for most men, though i...
Read the full Saw Palmetto monograph → Herb & supplement monographStinging Nettle
Interacts with 164 drugsStinging nettle is a common plant used as food and in traditional medicine, most often for prostate symptoms, allergies, and joint pain. The evidence is mixed and mostly preliminary, so it i...
Read the full Stinging Nettle monograph → Herb & supplement monographPipsissewa
Pipsissewa is a North American forest herb with a long history of traditional use as a diuretic and urinary remedy, but modern human research is very limited. There is not enough good eviden...
Read the full Pipsissewa monograph → Herb & supplement monographThuja
Interacts with 576 drugsThuja, also called northern white cedar or arborvitae, is a tree whose leaf and oil have a long history in folk and homeopathic medicine, especially for warts and immune support. Solid human...
Read the full Thuja monograph →Sources & How We Checked
Prostate Health's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 56 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Saw Palmetto 22 references
- Wilt TJ, Ishani A, Stark G, et al. Saw palmetto extracts for treatment of benign prostatic hyperplasia: a systematic review. JAMA 1998;280:1604-9. PubMed
- Carraro JC, Raynaud JP, Koch G, et al. Comparison of phytotherapy (Permixon) with finasteride in the treatment of benign prostate hyperplasia: a randomized international study of 1,098 patients. Prostate 1996;29:231-40. DOI
- Di Silverio F, D'Eramo G, Lubrano C, et al. Evidence that Serenoa repens extract displays an antiestrogenic activity in prostatic tissue of benign prostatic hypertrophy patients. Eur Urol 1992;21:309-14. PubMed
- Stepanov VN, Siniakova LA, Sarrazin B, Raynaud JP. Efficacy and tolerability of the lipidosterolic extract of Serenoa repens (Permixon) in benign prostatic hyperplasia: a double-blind comparison of two dosage regimens. Adv Ther 1999;16:231-41.
- Cheema P, El-Mefty O, Jazieh AR. Intraoperative haemorrhage associated with the use of extract of Saw Palmetto herb: a case report and review of literature. J Intern Med 2001;250:167-9. PubMed
- Jibrin I, Erinle A, Saidi A, Aliyu ZY. Saw palmetto-induced pancreatitis. South Med J 2006;99:611-2. PubMed
- Prager N, Bickett K, French N, Marcovici G. A randomized, double-blind, placebo-controlled trial to determine the effectiveness of botanically derived inhibitors of 5-alpha-reductase in the treatment of androgenetic alopecia. J Altern Complement Med 2002
- Avins AL, Bent S, Staccone S, et al. A detailed safety assessment of a saw palmetto extract. Complement Ther Med 2008;16:147-54. PubMed
- Morgia, G., Mucciardi, G., Gali, A., Madonia, M., Marchese, F., Di, Benedetto A., Romano, G., Bonvissuto, G., Castelli, T., Macchione, L., and Magno, C. Treatment of chronic prostatitis/chronic pelvic pain syndrome category IIIA with Serenoa repens plus
- Aliaev, IuG, Vinarov, A. Z., Lokshin, K. L., and Spivak, L. G. [Efficiency and safety of prostamol-Uno in patients with chronic abacterial prostatitis]. Urologiia. 2006;(1):47-50.
- Agbabiaka, T. B., Pittler, M. H., Wider, B., and Ernst, E. Serenoa repens (saw palmetto): a systematic review of adverse events. Drug Saf 2009;32(8):637-647. PubMed
- Wargo, K. A., Allman, E., and Ibrahim, F. A possible case of saw palmetto-induced pancreatitis. South.Med.J. 2010;103(7):683-685. PubMed
- Lapi, F., Gallo, E., Giocaliere, E., Vietri, M., Baronti, R., Pieraccini, G., Tafi, A., Menniti-Ippolito, F., Mugelli, A., Firenzuoli, F., and Vannacci, A. Acute liver damage due to Serenoa repens: a case report. Br.J.Clin.Pharmacol. 2010;69(5):558-560.
- Mantovani, F. Serenoa repens in benign prostatic hypertrophy: analysis of 2 Italian studies. Minerva Urol.Nefrol. 2010;62(4):335-340.
- Hanaka, M., Yoshii, C., Yatera, K., Ito, C., Chojin, Y., Nagata, S., Yamasaki, K., Nishida, C., Kawanami, T., Kawanami, Y., Ishimoto, H., and Mukae, H. [A case of rhabdomyolysis caused by saw palmetto of healthy foods]. J.UOEH. 6-1-2012;34(2):193-199. PubMed
- Miroddi, M., Carni, A., Mannucci, C., Moleti, M., Navarra, M., and Calapai, G. Hot flashes in a young girl: a wake-up call concerning Serenoa repens use in children. Pediatrics 2012;130(5):e1374-e1376.
- Braeckman J. The extract of Serenoa repens in the treatment of benign prostatic hyperplasia: a multicenter open study. Current Therapeutic Research 1994;55(7):776-785. DOI
- Jipescu D, Patel A, Bohra H, Pientka A. Rare case of saw palmetto induced heart block. JACC 2017;69(11) supplement:2310.
- Morabito P, Miroddi M, Giovinazzo S, Spina E, Calapai G. Serenoa repens as an endocrine disruptor in a 10-year-Old young girl: a new case report. Pharmacology. 2015;96(1-2):41-3. doi: 10.1159/000431327.
- Gammoudi R, Ameur K, Ouni B, et al. Fixed drug eruption to Serenoa repens: first case report and consideration of the use of herbal medicine. Dermatol Ther 2020 Aug 29:e14247.
- Paulis G, Paulis A, Perletti G. Serenoa repens and its effects on male sexual function. A systematic review and meta-analysis of clinical trials. Arch Ital Urol Androl 2021;93(4):475-480. PubMed
- Venkateswaran S, Declet-Bauzo R, Shodeinde M, Gilford P. Postoperative Retroperitoneal Hematoma: A Case of Saw Palmetto and the Importance of Primary Care Intervention. HCA Healthc J Med 2020;1(5):279-282. PubMed
Stinging Nettle 23 references
- Monographs on the medicinal uses of plant drugs. Exeter, UK: European Scientific Co-op Phytother, 1997.
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- Schulz V, Hansel R, Tyler VE. Rational Phytotherapy: A Physician's Guide to Herbal Medicine. Terry C. Telger, transl. 3rd ed. Berlin, GER: Springer, 1998.
- Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Mittman P. Randomized, double-blind study of freeze-dried Urtica dioica in the treatment of allergic rhinitis. Planta Med 1990;56:44-7.
- Vontobel HP, Herzog R, Rutishauser G, Kres H. [Results of a double-blind study on the effectiveness of ERU (extractum radicis Urticae) capsules in conservative treatment of benign prostatic hyperplasia]. (Abstract). Urologe A 1985;24:49-51.
- Randall C, Randall H, Dobbs F, et al. Randomized controlled trial of nettle sting for treatment of base-of-thumb pain. J R Soc Med 2000;93:305-9. PubMed
- Caliskaner Z, Karaayvaz M, Ozturk S. Misuse of a herb: stinging nettle (Urtica urens) induced severe tongue oedema. Complement Ther Med 2004;12:57-8. PubMed
- Krzeski, T., Kazon, M., Borkowski, A., Witeska, A., and Kuczera, J. Combined extracts of Urtica dioica and Pygeum africanum in the treatment of benign prostatic hyperplasia: double-blind comparison of two doses. Clin Ther 1993;15(6):1011-1020.
- Randall, C., Meethan, K., Randall, H., and Dobbs, F. Nettle sting of Urtica dioica for joint pain--an exploratory study of this complementary therapy. Complement Ther Med 1999;7(3):126-131. PubMed
- Tahri, A., Yamani, S., Legssyer, A., Aziz, M., Mekhfi, H., Bnouham, M., and Ziyyat, A. Acute diuretic, natriuretic and hypotensive effects of a continuous perfusion of aqueous extract of Urtica dioica in the rat. J Ethnopharmacol 2000;73(1-2):95-100. PubMed
- Sahin, M., Yilmaz, H., Gursoy, A., Demirel, A. N., Tutuncu, N. B., and Guvener, N. D. Gynaecomastia in a man and hyperoestrogenism in a woman due to ingestion of nettle (Urtica dioica). N.Z.Med.J. 2007;120(1265):U2803.
- Randall, C., Dickens, A., White, A., Sanders, H., Fox, M., and Campbell, J. Nettle sting for chronic knee pain: a randomised controlled pilot study. Complement Ther.Med. 2008;16(2):66-72. PubMed
- Rayburn, K., Fleischbein, E., Song, J., Allen, B., Kundert, M., Leiter, C., and Bush, T. Stinging nettle cream for osteoarthritis. Altern.Ther.Health Med. 2009;15(4):60-61.
- Oliver, F., Amon, E. U., Breathnach, A., Francis, D. M., Sarathchandra, P., Black, A. K., and Greaves, M. W. Contact urticaria due to the common stinging nettle (Urtica dioica)-- histological, ultrastructural and pharmacological studies. Clin Exp Dermato PubMed
- Kulze, A. and Greaves, M. Contact urticaria caused by stinging nettles. Br.J Dermatol. 1988;119(2):269-270. PubMed
- Patten G. Medicinal plant review: Urtica. Aust J Med Herbalism 1993;5(1):5-13.
- Maor D, Little M. Skin contact with a stinging tree requiring intensive care unit admission. Contact Dermatitis. 2017 Nov;77(5):335-37. PubMed
- Easton L, Vaid S, Nagel AK, Venci JV, Fortuna RJ. Stinging Nettle (Urtica dioica): An Unusual Case of Galactorrhea. Am J Case Rep 2021;22:e933999. PubMed
- Niazi B, Ahmed K, Ahmed M, Ali S, Song K, Elias S. Drug-Induced Liver Injury from Herbal Liver Detoxification Tea. Case Rep Gastroenterol 2022;16(3):612-617. PubMed
- Nnamani I, Tolu-Akinnawo O, Dufera RR, Akintunde A, Maliakkal B. Tinospora cordifolia (Guduchi/Giloy)-Induced Liver Injury: A Case Review. Cureus 2023;15(5):e39793. PubMed
Pipsissewa 1 reference
- Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
Thuja 10 references
- Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Millet Y, Jouglard J, Steinmetz MD, et al. Toxicity of some essential plant oils. Clinical and experimental study. Clin Toxicol 1981;18:1485-98. PubMed
- Gohla SH, Haubeck HD, Neth RD. Mitogenic activity of high molecular polysaccharide fractions isolated from the Cupressaceae Thuja occidentale L. I. Macrophage-dependent induction of CD-4-positive T-helper (Th+) lymphocytes. Leukemia 1988;2:528-33.
- Fetrow CW, Avila JR. Professional's Handbook of Complementary & Alternative Medicines. 1st ed. Springhouse, PA: Springhouse Corp., 1999.
- Henneicke-von Zepelin H, Hentschel C, Schnitker J, et al. Efficacy and safety of a fixed combination phytomedicine in the treatment of the common cold (acute viral respiratory tract infection): results of a randomised, double blind, placebo-controlled, m
- Naser, B., Bodinet, C., Tegtmeier, M., and Lindequist, U. Thuja occidentalis (Arbor vitae): A Review of its Pharmaceutical, Pharmacological and Clinical Properties. Evid.Based Complement Alternat.Med 2005;2(1):69-78.
- Patel R, Alavi F, Ortega S, Matela A. Herb-Induced Liver Injury by Cimicifuga racemosa and Thuja occidentalis Herbal Medications for Fertility. Case Rep Gastrointest Med 2021;2021:8858310. PubMed
- Ambooken B, Thomas M, Jisha KT. Papillary Eccrine Adenoma in a 5-year-old Girl Altered by Application of Thuja Ointment. J Cutan Aesthet Surg 2020;13(4):370-371. PubMed
- Badaoui A, Fougerousse AC. Contact dermatitis to linalool and limonene: Unusual sources of exposure. Ann Dermatol Venereol 2023;150(2):167-168. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC