Major interaction on record — check this product against your medications before combining. Based on 9 of 10 ingredients. Check your meds →
Dietary supplement

Prostatonic Ingredients & Drug Interactions

by Herbs Etc.

Prostatonic label
See full label image
Liquid Category: Botanical
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Prostatonic against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Prostatonic is a dietary supplement by Herbs Etc. with 10 active ingredients. Its ingredients are commonly taken for low libido / aphrodisiac, anxiety and stress, mood and mild low energy.Based on those ingredients, 687 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Yerba Mansa Root Extract, American Ginseng Root Extract, Saw Palmetto Berry Extract, Fresh. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Prostatonic by Herbs Etc.

Ask about any prescription or over-the-counter medication and we check it for interactions with Prostatonic by Herbs Etc. — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Prostatonic by Herbs Etc.

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Oct 6, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 10 active ingredients.
  • “Proprietary Extract Blend” is a proprietary blend — the label gives one combined amount (0.75 mL) without saying how much of each component you get.

Prostatonic contains 10 active ingredients in a proprietary liquid extract blend: damiana leaf, yarrow flower top, American ginseng root, pipsissewa herb, yerba mansa root, saw palmetto berry, dong quai root, stinging nettle root, cleavers herb, and sarsaparilla root. The product also contains alcohol, purified water, and glycerine as inactive ingredients.

Does it work?

Leans against
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Leans against

The strongest graded evidence we hold for the stated purpose leans against a benefit.

Why this rating?
  • The label markets this product for: Promotes healthy prostate function.
  • We looked for evidence on: Benign prostatic hyperplasia (BPH), Chronic prostatitis and chronic pelvic pain syndrome (CP/CPPS), Prostatitis, Urinary symptoms, Lower urinary tract symptoms.
  • The closest evidence on file: Saw Palmetto is rated "Possibly Ineffective" for Benign prostatic hyperplasia (BPH) (Natural Medicines).
  • Also on file: Stinging Nettle is rated "Insufficient Reliable Evidence To Rate" for Benign prostatic hyperplasia (BPH).
  • Also on file: Saw Palmetto is rated "Insufficient Reliable Evidence To Rate" for Chronic prostatitis and chronic pelvic pain syndrome (CP/CPPS), Prostatitis, Non-neurogenic lower urinary tract symptoms (LUTS).

The evidence for most ingredients in this formula is limited. American ginseng is possibly effective for upper respiratory tract infections.

Saw palmetto is possibly effective for symptoms related to transurethral resection of the prostate (TURP), though it's rated possibly ineffective for benign prostatic hyperplasia (BPH)—a key prostate condition. Stinging nettle is possibly effective for diabetes.

The remaining ingredients—damiana, yarrow, pipsissewa, yerba mansa, dong quai, cleavers, and sarsaparilla—lack sufficient reliable evidence for their traditional uses in our data.

The evidence, ingredient by ingredient Damiana Yarrow American Ginseng Pipsissewa Yerba Mansa Saw Palmetto Dong Quai Stinging Nettle

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 8 of the 9 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 9 of 9.
  • General safety write-ups exist for 9 of 9.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Damiana is likely fine in food or tea amounts for most adults, but human safety data are limited; at very high doses (200 grams of extract), it has caused serious neurological symptoms. Yarrow is generally well tolerated orally but can cause allergic skin reactions and dermatitis topically.

American ginseng is generally well tolerated short-term, though headache has been reported and long-term safety isn't well studied. Saw palmetto is generally well tolerated with mild, reversible side effects (abdominal pain, constipation, diarrhea, dizziness, fatigue, headache, nausea), though rare cases of heart rhythm changes have been reported.

Stinging nettle is generally well tolerated but can cause constipation or diarrhea; topical contact with the fresh plant causes itching and stinging. Dong quai is generally well tolerated but increases sun sensitivity and is reported to contain potentially carcinogenic constituents.

Pipsissewa, yerba mansa, sarsaparilla, and cleavers have limited safety data. Pregnancy: damiana, yarrow, pipsissewa, yerba mansa, saw palmetto, stinging nettle, and sarsaparilla should be avoided; American ginseng and dong quai are possibly unsafe.

Breastfeeding: all ingredients should be avoided due to insufficient safety information.

Side effects, ingredient by ingredient Damiana Yarrow American Ginseng Pipsissewa Yerba Mansa Saw Palmetto Dong Quai Stinging Nettle

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 8 of the 9 matched ingredients can interact with medications — Yarrow, Yerba Mansa, Sarsaparilla, Stinging Nettle, Damiana, among others.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications; heart-rhythm medications; lithium.
  • For scale: 687 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Prostatonic, check with your doctor or pharmacist if you take blood thinners like warfarin (Coumadin) or other anticoagulant or antiplatelet drugs—multiple ingredients may affect how they work. Also check if you take antidiabetes medications, lithium, immunosuppressants, MAOIs (depression medications), estrogens or birth control, diuretics (water pills), digoxin (Lanoxin), or CNS depressants (sedatives or sleep aids).

The interactions span Major and Moderate severity levels.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with graded evidence leaning against its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

Prostatonic is a 10-ingredient herbal formula with limited evidence for most uses and several important medication interactions to consider. The main concerns are with blood thinners (especially warfarin), diabetes medications, lithium, and hormone therapies.

If you take any prescription medications—especially for blood clotting, blood sugar, mood, heart rhythm, or hormones—talk with your doctor or pharmacist before starting this product.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 9 of 10 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Prostatonic, straight from the product label.

Brand Herbs Etc.
Barcode (UPC) 765704130018
Net contents 1 Fluid Ounce(s); 30 mL
Market status On market
Date entered into DSLD Nov 22, 2024
DSLD ID 320880
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Prostatonic by Herbs Etc., sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
30 Drop(s)
Maximum serving Sizes:
30 Drop(s)
Servings per container
40
UPC/BARCODE
765704130018
IngredientAmount% DV
Proprietary Extract Blend0.75 mL--
Damiana leaf extract0 NP--
Yarrow Flower Top Extract, Fresh0 NP--
American Ginseng Root Extract0 NP--
Pipsissewa Herb Extract0 NP--
Yerba Mansa Root Extract0 NP--
Saw Palmetto Berry Extract, Fresh0 NP--
Dong Quai Cured Root Extract0 NP--
Stinging Nettle Root Extract, Fresh0 NP--
Cleavers Herb Extract, Fresh0 NP--
Sarsparilla root extract0 NP--

Other ingredients: Alcohol, Water, Purified, Glycerine

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Promotes a healthy prostate function

Gluten free No artificial preservatives.

Vegan

Manufactured in Santa Fe, NM.

FDA Statement of Identity

Herbal Supplement

Formula

Prostatonic is made with healthy prostate function promoting herbs, including Saw Palmetto, Stinging Nettle, and Damiana.

General Statements

We apply our company philosophy to Prostatonic, as we do to all of our herbal medicines. That philosophy is to do what's right, which extends to choosing the right herbs, using the right processes, and making the right formulations that support your health needs. We do all of this to bring you herbal medicines made right.

Herbal medicine

Suggested/Recommended/Usage/Directions

Suggested use: Take 30 drops in water twice a day for an unlimited period of time.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Prostatonic by Herbs Etc. label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Prostatonic label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Prostatonic by Herbs Etc.

These are the 10 active ingredients this product is made of. Select any to open its full monograph.

Serving size30 Drop(s) Dosage formLiquid Servings per container40 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Other (inactive) ingredients: Alcohol, Water, Purified, Glycerine. These complete the product’s ingredient list but are not active constituents.

Interaction report

Prostatonic by Herbs Etc. Drug Interactions

Want to check YOUR meds against Prostatonic?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
687Drugs
2 Major 685 Moderate

Ingredients driving the most interactions

Yerba Mansa Root Extract 248
American Ginseng Root Extract 217
Saw Palmetto Berry Extract, Fresh 174
Stinging Nettle Root Extract, Fresh 164
Dong Quai Cured Root Extract 163

Individual Drug Interactions

The ingredients in Prostatonic interact with 687 drugs. Click any drug to see the details.

8 of the 10 ingredients in Prostatonic interact with drugs. Each result below shows which ingredient is responsible. Yerba Mansa Root Extract American Ginseng Root Extract Saw Palmetto Berry Extract, Fresh Stinging Nettle Root Extract, Fresh Dong Quai Cured Root Extract Damiana leaf extract Sarsparilla root extract Yarrow Flower Top Extract, Fresh

Each ingredient & the kinds of drugs it affects

For each ingredient in Prostatonic with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Yerba Mansa Root Extract1 drug type · 248 drugs

Cns Depressants

Theoretically, concomitant use might cause additive or prolonged sedative effects.

Likelihood Probable Evidence D
Yerba Mansa Root Extract full monograph & interactions

American Ginseng Root Extract4 drug types · 217 drugs

Warfarin (Coumadin)

American ginseng seems to decrease the effectiveness of warfarin therapy.
Healthy patients receiving warfarin 5 mg daily, who also take American ginseng 1 gram twice daily, seem to have a significantly reduced international normalized ratio (INR).

Likelihood Likely Evidence B
Antidiabetes Drugs

Theoretically, taking American ginseng with antidiabetes drugs might increase the risk of hypoglycemia.
American ginseng seems to lower postprandial blood glucose. Theoretically, concomitant use with antidiabetes drugs might enhance blood glucose lowering effects and possibly cause hypoglycemia.

Likelihood Probable Evidence B
Immunosuppressants

Theoretically, American ginseng use might interfere with immunosuppressive therapy.
American ginseng seems to stimulate immune function. Theoretically, American ginseng might decrease the effectiveness of immunosuppressant drugs.

Likelihood Possible Evidence D
Monoamine Oxidase Inhibitors (Maois)

Theoretically, American ginseng can interfere with MAOI therapy.
There is one case report of insomnia, headache, and tremors when an unspecified ginseng product was used with phenelzine (Nardil), an MAOI. There is also one case report of hypomania when an unspecified ginseng product was used with phenelzine. Theoretically, American ginseng may interfere with MAOI therapy.

Likelihood Possible Evidence D
American Ginseng Root Extract full monograph & interactions

Saw Palmetto Berry Extract, Fresh3 drug types · 174 drugs

Anticoagulant/Antiplatelet Drugs

Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Saw palmetto is reported to prolong bleeding time. Theoretically, it might increase the risk of bleeding when used concomitantly with anticoagulant or antiplatelet drugs.

Likelihood Possible Evidence D
Contraceptive Drugs

Saw palmetto might reduce the effectiveness of contraceptive drugs.
Saw palmetto might have antiestrogenic effects. Theoretically, it might interfere with contraceptive drugs taken concomitantly.

Likelihood Possible Evidence B
Estrogens

Saw palmetto might reduce the effectiveness of estrogens.
Saw palmetto might have antiestrogenic effects. Theoretically, it might interfere with estrogens taken concomitantly.

Likelihood Possible Evidence B
Saw Palmetto Berry Extract, Fresh full monograph & interactions

Stinging Nettle Root Extract, Fresh4 drug types · 164 drugs

Antidiabetes Drugs

Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Clinical research shows that stinging nettle might decrease blood glucose levels in patients with diabetes.

Likelihood Possible Evidence B
Diuretic Drugs

Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Animal research suggests that the above ground parts and roots of stinging nettle may have a diuretic effect.

Likelihood Possible Evidence D
Lithium

Theoretically, stinging nettle might reduce excretion and increase levels of lithium.
Animal research suggests that stinging nettle has diuretic and natriuretic properties, which could alter the excretion of lithium. The dose of lithium might need to be decreased.

Likelihood Possible Evidence D
Warfarin (Coumadin)

There is some concern that stinging nettle might decrease the effects of anticoagulant drugs such as warfarin.
Stinging nettle contains a significant amount of vitamin K. When taken in large quantities, this might interfere with the activity of warfarin.

Likelihood Possible Evidence D
Stinging Nettle Root Extract, Fresh full monograph & interactions

Dong Quai Cured Root Extract3 drug types · 163 drugs

Warfarin (Coumadin)

Dong quai may increase the risk of bleeding when used with warfarin.
Case reports suggest that concomitant use of dong quai with warfarin can increase the anticoagulant effects of warfarin and increase the risk of bleeding. In one case, after 4 weeks of taking dong quai 565 mg once or twice daily, the international normalized ratio (INR) increased to 4.9. The INR normalized 4 weeks after discontinuation of dong quai.

Likelihood Probable Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, dong quai may increase the risk of bleeding when used with anticoagulant or antiplatelet drugs; however, research is conflicting.
Animal studies suggest that dong quai has antithrombin activity and inhibits platelet aggregation due to its coumarin components. Additionally, some case reports in humans suggest that dong quai can increase the anticoagulant effects of warfarin. However, clinical research in healthy adults shows that taking 1 gram of dong quai root daily for 3 weeks does not significantly inhibit platelet aggregation or cause bleeding. Until more is known, use dong quai with caution in patients taking antiplatelet/anticoagulant drugs.

Likelihood Possible Evidence D
Estrogens

Theoretically, dong quai may reduce the effects of estrogens.
Dong quai has estrogenic effects. Theoretically, concomitant use of large amounts of dong quai might interfere with hormone replacement therapy due to competition for estrogen receptors.

Likelihood Possible Evidence D
Dong Quai Cured Root Extract full monograph & interactions

Damiana leaf extract1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking damiana with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research shows that taking damiana lowers blood glucose level.

Likelihood Possible Evidence D
Damiana leaf extract full monograph & interactions

Sarsparilla root extract2 drug types · 2 drugs

Digoxin (Lanoxin)

Theoretically, concomitant use of sarsaparilla with digoxin might increase the risk of cardiac toxicity.
Sarsaparilla is thought to have diuretic properties, which could potentially cause potassium loss. Overuse or misuse of sarsaparilla with cardiac glycoside therapy might increase the risk of cardiac toxicity due to potassium loss.

Likelihood Possible Evidence D
Lithium

Theoretically, sarsaparilla might increase the effects and adverse effects of lithium.
Sarsaparilla is thought to have diuretic properties. Due to these effects, sarsaparilla might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Sarsparilla root extract full monograph & interactions

Yarrow Flower Top Extract, Fresh1 drug type · 1 drug

Lithium

Theoretically, taking yarrow with lithium might increase the levels and adverse effects of lithium.
Animal research shows that yarrow has diuretic activity. Theoretically, due to these potential diuretic effects, yarrow might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Yarrow Flower Top Extract, Fresh full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Prostatonic, from the product label.

Herbs Etc.

Name
Herbs, Etc., Inc.
Street Address
1340 Rufina Circle
City
Santa Fe
State
NM
ZipCode
87507
Web Address
www.herbsetc.com
Pharmacist Counseling Corner

Prostatonic by Herbs Etc.: Common Questions

Does Prostatonic by Herbs Etc. interact with any medications?
Yes. Based on its ingredients, Prostatonic has a known interaction with 687 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Prostatonic contains 10 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on warfarin or another blood thinner?
Not without checking with your doctor or pharmacist first. American ginseng and dong quai in this product have documented interactions with warfarin—one decreases its effectiveness, the other increases bleeding risk. Stinging nettle may also reduce warfarin's effect. Your prescriber needs to know you're considering this product.
Does this product actually help with prostate health?
Saw palmetto, the most studied ingredient here for prostate issues, is possibly effective for TURP-related symptoms but rated possibly ineffective for benign prostatic hyperplasia (BPH)—a common prostate condition. The other ingredients lack reliable evidence for prostate use in our data.
Is this safe to take if I'm pregnant or breastfeeding?
No. The safety data advise against it during pregnancy for damiana, yarrow, pipsissewa, yerba mansa, saw palmetto, and stinging nettle; American ginseng and dong quai are possibly unsafe. For breastfeeding, all ingredients should be avoided due to insufficient safety information. Talk with your doctor about alternatives.
What are the most common side effects?
Saw palmetto and stinging nettle are generally well tolerated with mild effects like diarrhea, constipation, dizziness, or headache. Damiana is fine at food-tea amounts but very high doses have caused serious neurological reactions. Yarrow can cause allergic skin reactions in some people.
Can I take this with diabetes medication?
Not without checking with your doctor first. Damiana, American ginseng, and stinging nettle may all lower blood sugar, so taking them with diabetes drugs could raise the risk of low blood sugar (hypoglycemia). Your dose or monitoring may need adjustment.
What is the proprietary blend, and why isn't each ingredient listed with an amount?
The product uses a proprietary extract blend, which means the exact amount of each active ingredient isn't disclosed—that's a trademark choice by the manufacturer. You're getting all 10 listed herbs, but we can't tell you the dose of each one.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Prostatonic label
Go deeper

The Full Monographs Behind Prostatonic’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Damiana

Interacts with 86 drugs

Damiana is a traditional herb most famous as an aphrodisiac and mild mood-lifter, but solid human evidence for any of its uses is very limited. It is generally well tolerated in the small am...

Read the full Damiana monograph → Herb & supplement monograph

Yarrow

Interacts with 1 drug

Yarrow is a traditional herb long used for wounds, digestive complaints, and colds, but high-quality human studies are very limited, so its benefits are not well proven. It is generally used...

Read the full Yarrow monograph → Herb & supplement monograph

American Ginseng

Interacts with 217 drugs

American ginseng is an herbal root used as an 'adaptogen' to support energy, stress, immune function, and blood sugar. Some uses—such as reducing the chance or length of colds and modestly l...

Read the full American Ginseng monograph → Herb & supplement monograph

Pipsissewa

Pipsissewa is a North American forest herb with a long history of traditional use as a diuretic and urinary remedy, but modern human research is very limited. There is not enough good eviden...

Read the full Pipsissewa monograph → Herb & supplement monograph

Yerba Mansa

Interacts with 248 drugs

Yerba mansa is a traditional Southwestern and Mexican medicinal plant used for sore throats, skin problems, and infections. Modern scientific evidence in humans is very limited, so its effec...

Read the full Yerba Mansa monograph → Herb & supplement monograph

Saw Palmetto

Interacts with 174 drugs

Saw palmetto is a plant extract most often used for urinary symptoms linked to an enlarged prostate (BPH). The best research suggests it works no better than a placebo for most men, though i...

Read the full Saw Palmetto monograph → Herb & supplement monograph

Dong Quai

Interacts with 163 drugs

Dong Quai is a traditional Chinese herb often called "female ginseng" and is mostly used for menstrual and menopausal complaints. High-quality scientific evidence that it works for these use...

Read the full Dong Quai monograph → Herb & supplement monograph

Stinging Nettle

Interacts with 164 drugs

Stinging nettle is a common plant used as food and in traditional medicine, most often for prostate symptoms, allergies, and joint pain. The evidence is mixed and mostly preliminary, so it i...

Read the full Stinging Nettle monograph → Herb & supplement monograph

Sarsaparilla

Interacts with 2 drugs

Sarsaparilla is a traditional root used in teas, tonics, and old-fashioned root beer flavoring. Modern evidence for its health claims is very limited and comes mostly from lab studies, so it...

Read the full Sarsaparilla monograph →
Sources

Sources & How We Checked

Prostatonic's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 92 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Damiana 2 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Alarcon-Aquilar FJ, Roman-Ramos R, Perez-Gutierrez S, et al. Study of the anti-hyperglycemic effect of plants used as antidiabetics. J Ethnopharmacol 1998;61:101-10. PubMed

See these in context on the Damiana monograph →

Yarrow 8 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Uter, W., Nohle, M., Randerath, B., and Schwanitz, H. J. Occupational contact urticaria and late-phase bronchial asthma caused by compositae pollen in a florist. Am J Contact Dermat. 2001;12(3):182-184. DOI
  3. Schempp, C. M., Schopf, E., and Simon, J. C. [Plant-induced toxic and allergic dermatitis (phytodermatitis)]. Hautarzt 2002;53(2):93-97.
  4. Jovanovic, M., Poljacki, M., Duran, V., Vujanovic, L., Sente, R., and Stojanovic, S. Contact allergy to Compositae plants in patients with atopic dermatitis. Med Pregl. 2004;57(5-6):209-218. PubMed
  5. Becker LC, Bergfeld WF, Belsito DV, et al. Safety assessment of Achillea millefolium as used in cosmetics. Int J Toxicol. 2016;35(3 suppl):5S-15S.
  6. Zakeri S, Esmaeilzadeh S, Gorji N, Memariani Z, Moeini R, Bijani A. The effect of Achillea millefolium L. on vulvovaginal candidiasis compared with clotrimazole: A randomized controlled trial. Complement Ther Med. 2020;52:102483. PubMed
  7. de Souza P, Crestani S, da Silva Rde C, et al. Involvement of bradykinin and prostaglandins in the diuretic effects of Achillea millefolium L. (Asteraceae). J Ethnopharmacol. 2013 Aug 26;149(1):157-61. PubMed
  8. Miranzadeh S, Adib-Hajbaghery M, Soleymanpoor L, Ehsani M. Effect of adding the herb Achillea millefolium on mouthwash on chemotherapy induced oral mucositis in cancer patients: A double-blind randomized controlled trial. Eur J Oncol Nurs. 2015;19(3):207- PubMed

See these in context on the Yarrow monograph →

American Ginseng 12 references
  1. Shader RI, Greenblatt DJ. Phenelzine and the dream machine-ramblings and reflections. J Clin Psychopharmacol 1985;5:65. PubMed
  2. Jones BD, Runikis AM. Interaction of ginseng with phenelzine. J Clin Psychopharmacol 1987;7:201-2. PubMed
  3. Janetzky K, Morreale AP. Probable interaction between warfarin and ginseng. Am J Health Syst Pharm 1997;54:692-3. PubMed
  4. Vuksan V, Sievenpiper JL, Koo VY, et al. American ginseng (Panax quinquefolius L) reduces postprandial glycemia in nondiabetic subjects and subjects with type 2 diabetes mellitus. Arch Intern Med 2000;160:1009-13. PubMed
  5. Vuksan V, Stavro MP, Sievenpiper JL, et al. Similar postprandial glycemic reductions with escalation of dose and administration time of American ginseng in type 2 diabetes. Diabetes Care 2000;23:1221-6. PubMed
  6. Chan LY, Chiu PY, Lau TK. An in-vitro study of ginsenoside Rb(1)-induced teratogenicity using a whole rat embryo culture model. Hum Reprod 2003;18:2166-8..
  7. McElhaney JE, Gravenstein S, Cole SK, et al. A Placebo-Controlled Trial of a Proprietary Extract of North American Ginseng (CVT-E002) to Prevent Acute Respiratory Illness in Institutionalized Older Adults. J Am Geriatr Soc 2004;52:13-9. PubMed
  8. Yuan CS, Wei G, Dey L, et al. American ginseng reduces warfarin's effect in healthy patients: a randomized, controlled trial. Ann Intern Med 2004;141:23-7.
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Pipsissewa 2 references
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Yerba Mansa 1 reference
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See these in context on the Yerba Mansa monograph →

Saw Palmetto 22 references
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Dong Quai 19 references
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Stinging Nettle 23 references
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Sarsaparilla 3 references
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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