Psor-Rbs Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Psor-Rbs against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Psor-Rbs is a dietary supplement by Loomis Enzymes with 4 active ingredients. Its ingredients are commonly taken for high cholesterol, liver health, brain and memory support.Based on those ingredients, 226 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Borage Oil, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Psor-Rbs by Loomis Enzymes
Ask about any prescription or over-the-counter medication and we check it for interactions with Psor-Rbs by Loomis Enzymes — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Psor-Rbs by Loomis Enzymes
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Partial disclosure
The active ingredients listed are lipase, cellulase, lecithin, a proprietary enzyme blend, and borage oil powder. Our data discusses lipase mainly in relation to digestive conditions such as inflammatory bowel disease and dyspepsia, lecithin in relation to Alzheimer disease, anxiety, and bipolar disorder, and borage in relation to eczema and ADHD.
The proprietary blend is listed as a group, and its component ingredients are the individual items named above. The product also lists inactive ingredients: microcrystalline cellulose, cellulose, water, and phytase.
These are non-active components that help form the capsule and product.
Does it work?
Couldn't assess
For lipase, the evidence for inflammatory bowel disease, dyspepsia, and prematurity is rated Insufficient Reliable Evidence To Rate. For lecithin, Alzheimer disease is rated Likely Ineffective, while age-related cognitive decline, TPN-associated hepatic steatosis, anxiety, and bipolar disorder are rated Insufficient Reliable Evidence To Rate.
For borage, atopic dermatitis (eczema) is rated Possibly Ineffective, and ADHD, acute respiratory distress syndrome, and alcoholism are rated Insufficient Reliable Evidence To Rate. We hold no effectiveness rating for cellulase or the proprietary enzyme blend.
How safe is it?
Well-documented data
Lipase is generally well tolerated in supplement form, but people with serious digestive conditions should use it only under medical guidance. Its pregnancy entry has no rating on file, and the safety notes say there is little safety data on supplemental lipase in pregnancy, so use it only if your doctor advises it.
Breastfeeding has not been well studied, so check with your healthcare provider first. Lecithin is rated Likely Safe in pregnancy.
Its breastfeeding notes say to check with your healthcare provider first, and it can cause allergic skin reactions in people with egg or soy allergies. Borage is rated Likely Unsafe in pregnancy, and the safety data advises against it because of possible liver-toxic alkaloids.
We hold no pregnancy or breastfeeding entry for cellulase or the enzyme blend.
Meds to double-check
Moderate interaction found
Double-check with your doctor or pharmacist before taking this product if you use anticoagulant or antiplatelet drugs, phenothiazines, or CYP3A4 inducers, all rated Moderate in our data. Borage is the ingredient responsible for all three.
We could not check cellulase or the proprietary enzyme blend, so their medication interactions are not covered here.
The bottom line
Scorecard at a glancePartially disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product may be of interest to people looking into lipase, lecithin, or borage for the uses covered in our data, though the evidence for most of those uses is not established. People with serious digestive conditions, people who are pregnant or breastfeeding, and anyone taking blood thinners, seizure-related or antipsychotic medications, or CYP3A4-affected drugs should be especially careful.
Talk it over with your own doctor or pharmacist before you start.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Psor-Rbs, straight from the product label.
| Brand | Loomis Enzymes |
|---|---|
| Barcode (UPC) | 697706011708 |
| Net contents | 180 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Feb 23, 2025 |
| DSLD ID | 327547 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Psor-Rbs by Loomis Enzymes, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Lipase | 0 NP | -- |
| Cellulase | 0 NP | -- |
| Lecithin | 400 mg | -- |
| Proprietary Enzyme Blend | 84 mg | -- |
| Borage Oil, Powder | 400 mg | -- |
Other ingredients: Microcrystalline Cellulose, Cellulose, Water, Phytase
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
pHBS pH Balancing System
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Precautions
Keep out of reach of children
Note: Consult your physician before using this product if you are pregnant, nursing, taking medication, or have a medical condition.
Do not use if inner or outer seal is broken, torn, or missing.
Contains soy
Storage
To ensure freshness and potency, keep bottle tightly closed and store in a cool, dry place.
FDA Statement of Identity
A Dietary Supplement
Suggested/Recommended/Usage/Directions
Directions for use: Take 4 capsules 3 times daily with meals, or as directed.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Psor-Rbs by Loomis Enzymes label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Psor-Rbs by Loomis Enzymes
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size4 Capsule(s) Dosage formCapsule Servings per container45 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Lecithin
No knowninteractions
Lecithin is a natural fatty substance found in foods and made by the body that is widely used as a supplement and food emulsifier. Evidence supporting...
Lecithin monograph & interactionsProprietary Enzyme Blend
- › Lipase
- › Cellulase
Borage Oil, Powder
Interacts with226 drugs
Borage is a Mediterranean herb whose seed oil is rich in gamma-linolenic acid (GLA), an omega-6 fatty acid studied mostly for skin conditions and arth...
Borage Oil, Powder monograph & interactionsOther (inactive) ingredients: Microcrystalline Cellulose, Cellulose, Water, Phytase. These complete the product’s ingredient list but are not active constituents.
Psor-Rbs by Loomis Enzymes Drug Interactions
HelloPharmacist Interaction Report
Psor-Rbs from Loomis Enzymes can interact with certain medications, and the interactions we have on file all come from its borage oil powder.
The most serious of these are Moderate, and the first is with anticoagulant and antiplatelet drugs (medicines that thin the blood or keep platelets from clumping). Borage seed oil may theoretically increase the risk of bleeding when taken with them.
Read the full breakdown — every affected drug type, severity by severity
The other drug types are phenothiazines (certain antipsychotic and anti-nausea medicines), where borage may theoretically raise the risk of seizures, Moderate severity. CYP3A4 inducers (drugs that speed up the liver enzyme CYP3A4) are also listed as Moderate, because they may theoretically raise levels of liver-toxic plant compounds found in some borage plant parts.
Altogether, these interactions span 227 individual medications.
Our data documents no interactions for lipase or lecithin, though that is not a guarantee none exist. We could not check cellulase or the proprietary enzyme blend, so we have no data on them.
Use the search tool on this page to check your exact medications, and talk with your own doctor or pharmacist before combining this product with anything you take.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Psor-Rbs?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Psor-Rbs interact with 226 drugs. Click any drug to see the details.
1 of the 4 ingredients in Psor-Rbs interact with drugs. Each result below shows which ingredient is responsible. Borage Oil, Powder
Aspirin, Butalbital, Caffeine, PhenacetinMarnal
How Aspirin, Butalbital, Caffeine, Phenacetin interacts with Psor-Rbs — through 1 ingredient. Tap an ingredient for the detail:
Borage Oil, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil, Powder + Aspirin, Butalbital, Caffeine, Phenacetin interactionAspirin, CaffeineAnacin
How Aspirin, Caffeine interacts with Psor-Rbs — through 1 ingredient. Tap an ingredient for the detail:
Borage Oil, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil, Powder + Aspirin, Caffeine interactionAspirin, Caffeine, Codeine PhosphateAnacin w/ Codeine
How Aspirin, Caffeine, Codeine Phosphate interacts with Psor-Rbs — through 1 ingredient. Tap an ingredient for the detail:
Borage Oil, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil, Powder + Aspirin, Caffeine, Codeine Phosphate interactionAspirin, Caffeine, Dihydrocodeine BitartrateSynalgos DC
How Aspirin, Caffeine, Dihydrocodeine Bitartrate interacts with Psor-Rbs — through 1 ingredient. Tap an ingredient for the detail:
Borage Oil, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil, Powder + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAspirin, Caffeine, Dover's PwdAcedoval, Dovacet
How Aspirin, Caffeine, Dover's Pwd interacts with Psor-Rbs — through 1 ingredient. Tap an ingredient for the detail:
Borage Oil, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil, Powder + Aspirin, Caffeine, Dover's Pwd interactionAspirin, Caffeine, HydrocodoneDamason-P
How Aspirin, Caffeine, Hydrocodone interacts with Psor-Rbs — through 1 ingredient. Tap an ingredient for the detail:
Borage Oil, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil, Powder + Aspirin, Caffeine, Hydrocodone interactionAspirin, Caffeine, Isobutylallylbarbituric Acid, PhenacetinLanorinal
How Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin interacts with Psor-Rbs — through 1 ingredient. Tap an ingredient for the detail:
Borage Oil, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil, Powder + Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin interactionAspirin, Caffeine, OrphenadrineInvagesic, Invagesic Forte, Norgesic, Norgesic Forte, Orphengesic, Orphengesic Forte
How Aspirin, Caffeine, Orphenadrine interacts with Psor-Rbs — through 1 ingredient. Tap an ingredient for the detail:
Borage Oil, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil, Powder + Aspirin, Caffeine, Orphenadrine interactionAspirin, Caffeine, Phenacetin, PropoxypheneMargesic Comp. 65
How Aspirin, Caffeine, Phenacetin, Propoxyphene interacts with Psor-Rbs — through 1 ingredient. Tap an ingredient for the detail:
Borage Oil, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil, Powder + Aspirin, Caffeine, Phenacetin, Propoxyphene interactionAspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium OxideBufferin
How Aspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium Oxide interacts with Psor-Rbs — through 1 ingredient. Tap an ingredient for the detail:
Borage Oil, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil, Powder + Aspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium Oxide interactionAspirin, CarisoprodolSoma Compound
How Aspirin, Carisoprodol interacts with Psor-Rbs — through 1 ingredient. Tap an ingredient for the detail:
Borage Oil, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil, Powder + Aspirin, Carisoprodol interactionAspirin, Carisoprodol, Codeine PhosphateSoma Compound w/ Codeine
How Aspirin, Carisoprodol, Codeine Phosphate interacts with Psor-Rbs — through 1 ingredient. Tap an ingredient for the detail:
Borage Oil, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil, Powder + Aspirin, Carisoprodol, Codeine Phosphate interactionAspirin, Chlorpheniramine, PhenylpropanolamineAlka-Seltzer Plus Cold
How Aspirin, Chlorpheniramine, Phenylpropanolamine interacts with Psor-Rbs — through 1 ingredient. Tap an ingredient for the detail:
Borage Oil, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil, Powder + Aspirin, Chlorpheniramine, Phenylpropanolamine interactionAspirin, Citric Acid, Sodium BicarbonateAlka-Seltzer Pain Reliever and Antacid
How Aspirin, Citric Acid, Sodium Bicarbonate interacts with Psor-Rbs — through 1 ingredient. Tap an ingredient for the detail:
Borage Oil, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil, Powder + Aspirin, Citric Acid, Sodium Bicarbonate interactionAspirin, Codeine PhosphateAspirin w/ Codeine
How Aspirin, Codeine Phosphate interacts with Psor-Rbs — through 1 ingredient. Tap an ingredient for the detail:
Borage Oil, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil, Powder + Aspirin, Codeine Phosphate interactionAspirin, Codeine Phosphate, MethocarbamolRobaxisal C
How Aspirin, Codeine Phosphate, Methocarbamol interacts with Psor-Rbs — through 1 ingredient. Tap an ingredient for the detail:
Borage Oil, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil, Powder + Aspirin, Codeine Phosphate, Methocarbamol interactionAspirin, Codeine Phosphate, PhenobarbitalPhenaphen
How Aspirin, Codeine Phosphate, Phenobarbital interacts with Psor-Rbs — through 1 ingredient. Tap an ingredient for the detail:
Borage Oil, PowderAnticoagulant/antiplatelet Drugs, Cytochrome P450 3a4 (cyp3a4) Inducers Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil, Powder + Aspirin, Codeine Phosphate, Phenobarbital interactionAspirin, Diphenhydramine, PhenylpropanolamineAlka Seltzer Plus Night Time Effervescent
How Aspirin, Diphenhydramine, Phenylpropanolamine interacts with Psor-Rbs — through 1 ingredient. Tap an ingredient for the detail:
Borage Oil, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil, Powder + Aspirin, Diphenhydramine, Phenylpropanolamine interactionAspirin, DipyridamoleAggrenox, Asasantin Retard
How Aspirin, Dipyridamole interacts with Psor-Rbs — through 1 ingredient. Tap an ingredient for the detail:
Borage Oil, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil, Powder + Aspirin, Dipyridamole interactionAspirin, Ethoheptazine, MeprobamateEquagesic
How Aspirin, Ethoheptazine, Meprobamate interacts with Psor-Rbs — through 1 ingredient. Tap an ingredient for the detail:
Borage Oil, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil, Powder + Aspirin, Ethoheptazine, Meprobamate interactionAspirin, HydrocodoneAlor 5 500, Lortab ASA
How Aspirin, Hydrocodone interacts with Psor-Rbs — through 1 ingredient. Tap an ingredient for the detail:
Borage Oil, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil, Powder + Aspirin, Hydrocodone interactionAspirin, MeprobamateMicrainin
How Aspirin, Meprobamate interacts with Psor-Rbs — through 1 ingredient. Tap an ingredient for the detail:
Borage Oil, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil, Powder + Aspirin, Meprobamate interactionAspirin, MethocarbamolRobaxisal
How Aspirin, Methocarbamol interacts with Psor-Rbs — through 1 ingredient. Tap an ingredient for the detail:
Borage Oil, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil, Powder + Aspirin, Methocarbamol interactionAspirin, OmeprazoleYosprala
How Aspirin, Omeprazole interacts with Psor-Rbs — through 1 ingredient. Tap an ingredient for the detail:
Borage Oil, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil, Powder + Aspirin, Omeprazole interactionAspirin, OxycodonePercodan
How Aspirin, Oxycodone interacts with Psor-Rbs — through 1 ingredient. Tap an ingredient for the detail:
Borage Oil, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil, Powder + Aspirin, Oxycodone interactionAspirin, PentazocineTalwin Compound
How Aspirin, Pentazocine interacts with Psor-Rbs — through 1 ingredient. Tap an ingredient for the detail:
Borage Oil, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Borage Oil, Powder + Aspirin, Pentazocine interactionAtropine, Hyoscyamine, PhenobarbitalHypnaldyne
How Atropine, Hyoscyamine, Phenobarbital interacts with Psor-Rbs — through 1 ingredient. Tap an ingredient for the detail:
Borage Oil, PowderCytochrome P450 3a4 (cyp3a4) Inducers Moderate
Interaction Summary
Theoretically, taking borage with drugs that induce CYP3A4 might increase levels of pyrrolizidine alkaloid (PA) toxic metabolites.
Read the full Borage Oil, Powder + Atropine, Hyoscyamine, Phenobarbital interactionAtropine, Hyoscyamine, Phenobarbital, ScopolamineBarbidonna No. 2, Belladonna Phenobarbital
How Atropine, Hyoscyamine, Phenobarbital, Scopolamine interacts with Psor-Rbs — through 1 ingredient. Tap an ingredient for the detail:
Borage Oil, PowderCytochrome P450 3a4 (cyp3a4) Inducers Moderate
Interaction Summary
Theoretically, taking borage with drugs that induce CYP3A4 might increase levels of pyrrolizidine alkaloid (PA) toxic metabolites.
Read the full Borage Oil, Powder + Atropine, Hyoscyamine, Phenobarbital, Scopolamine interactionAtropine, Hyoscyamine, Scopolamine, PhenobarbitalBarbeloid, Donnatal #2, Donphen
How Atropine, Hyoscyamine, Scopolamine, Phenobarbital interacts with Psor-Rbs — through 1 ingredient. Tap an ingredient for the detail:
Borage Oil, PowderCytochrome P450 3a4 (cyp3a4) Inducers Moderate
Interaction Summary
Theoretically, taking borage with drugs that induce CYP3A4 might increase levels of pyrrolizidine alkaloid (PA) toxic metabolites.
Read the full Borage Oil, Powder + Atropine, Hyoscyamine, Scopolamine, Phenobarbital interactionAtropine, PhenobarbitalAnthrocol
How Atropine, Phenobarbital interacts with Psor-Rbs — through 1 ingredient. Tap an ingredient for the detail:
Borage Oil, PowderCytochrome P450 3a4 (cyp3a4) Inducers Moderate
Interaction Summary
Theoretically, taking borage with drugs that induce CYP3A4 might increase levels of pyrrolizidine alkaloid (PA) toxic metabolites.
Read the full Borage Oil, Powder + Atropine, Phenobarbital interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Psor-Rbs with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Borage Oil, Powder
Anticoagulant/Antiplatelet Drugs
Theoretically, borage seed oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In healthy individuals, borage seed oil supplementation does not seem to affect platelet aggregation. However, gamma-linolenic acid, a constituent of borage seed oil, seems to decrease platelet aggregation by 45% and increase the risk of bleeding by 40% in animal and clinical research.
Cytochrome P450 3A4 (Cyp3A4) Inducers
Theoretically, taking borage with drugs that induce CYP3A4 might increase levels of pyrrolizidine alkaloid (PA) toxic metabolites.
Although borage seed oil contains little to no PAs, some borage plant parts, such as the leaf, flower, and seed, can contain hepatotoxic PAs. Hepatotoxic PAs are substrates of CYP3A4, which converts these chemicals into toxic metabolites. Tell patients to avoid borage preparations that are not certified and labeled as hepatotoxic PA-free.
Phenothiazines
Theoretically, taking borage sed oil with phenothiazines might increase the risk of seizures.
Borage seed oil contains gamma-linolenic acid (GLA). There is concern that taking supplements containing GLA might cause seizures, or lower the seizure threshold, when taken with phenothiazines. This is based on limited data from two reports published in the 1980s. In one report, three patients with schizophrenia who had received phenothiazines developed EEG changes suggestive of temporal lobe epilepsy after starting treatment with evening primrose, another source of GLA. However, none experienced an actual seizure. In the other report, two patients with schizophrenia who were stabilized on phenothiazines developed seizures when evening primrose 4 grams daily was added. One of these patients had a prior history of seizures. It is unclear whether evening primrose had any additive epileptogenic effects with the phenothiazines, but there is no evidence that taking GLA-containing supplements alone can cause seizures.
Brand information
Manufacturer and brand details for Psor-Rbs, from the product label.
Loomis Enzymes
See all Loomis Enzymes products- Name
- Loomis Enzymes, LLC
- City
- Fitchburg
- State
- Wisconsin
- ZipCode
- 53719
- Phone Number
- 1-800-614-4400
- Web Address
- www.loomisenzymes.com
Psor-Rbs by Loomis Enzymes: Common Questions
Does Psor-Rbs by Loomis Enzymes interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is Psor-Rbs okay to take during pregnancy?
Does lecithin work for Alzheimer disease?
Does borage help with eczema?
What are the common side effects of borage oil?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Psor-Rbs is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Psor-Rbs’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Lecithin
Lecithin is a natural fatty substance found in foods and made by the body that is widely used as a supplement and food emulsifier. Evidence supporting most of its health claims is limited, t...
Read the full Lecithin monograph → Herb & supplement monographLipase
Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy for people who cannot make enough of their...
Read the full Lipase monograph → Herb & supplement monographBorage
Interacts with 226 drugsBorage is a Mediterranean herb whose seed oil is rich in gamma-linolenic acid (GLA), an omega-6 fatty acid studied mostly for skin conditions and arthritis with mixed results. The plant's le...
Read the full Borage monograph →Sources & How We Checked
Psor-Rbs's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 21 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Lipase 1 reference
- Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed
Lecithin 9 references
- Buchman AL, Dubin M, Jenden D, et al. Lecithin increases plasma free choline and decreases hepatic steatosis in long-term total parenteral nutrition patients. Gastroenterology 1992;102:1363-70.
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
- Chatellier G, Lacomblez L. Tacrine (tetrahydroaminoacridine; THA) and lecithin in senile dementia of the Alzheimer type: a multicentre trial. Groupe Francais d'Etude de la Tetrahydroaminoacridine. BMJ 1990;300:495-9.
- Gelenberg AJ, Dorer DJ, Wojcik JD, et al. A crossover study of lecithin treatment of tardive dyskinesia. J Clin Psychiatry 1990;51:149-53.
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