Interactions on record — worth a quick check against your medications. Based on 6 of 11 ingredients. Check your meds →
Dietary supplement

PUMP Cherry Burst Ingredients & Drug Interactions

by Core Nutritionals

PUMP Cherry Burst label
See full label image
Powder Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking PUMP Cherry Burst against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

PUMP Cherry Burst is a dietary supplement by Core Nutritionals with 11 active ingredients. Its ingredients are commonly taken for athletic performance and endurance, high-intensity exercise capacity, reducing muscle fatigue.Based on those ingredients, 677 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Reishi, Lion's Mane, Shiitake. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against PUMP Cherry Burst by Core Nutritionals

Ask about any prescription or over-the-counter medication and we check it for interactions with PUMP Cherry Burst by Core Nutritionals — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of PUMP Cherry Burst by Core Nutritionals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 5 of its 11 active ingredients.
  • “Peak02” is listed as a grouped ingredient — the label gives one combined amount (2,000 mg) without saying how much of each component you get.

PUMP Cherry Burst contains 11 active ingredients designed to support athletic performance and mental function. Beta-alanine is included for athletic and physical performance.

Alpha-glycerylphosphorylcholine (alpha-GPC) is a cognitive support compound. The formula also features several mushroom extracts—lion's mane, cordyceps, reishi, and shiitake—along with performance-focused ingredients like L-citrulline and branded compounds NO3-T, Hydromax, and Peak02.

Turkey Tail mushroom and King Trumpet round out the blend. The product also contains inactive ingredients including malic acid, citric acid, natural and artificial flavoring, and sweeteners.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: pump, endurance, strength, and focus pre-workout.
  • We looked for evidence on: Athletic performance, Physical performance, Exercise-induced muscle breakdown, Fatigue, Cognitive function, Memory — and 3 related terms.
  • The strongest evidence on file: Beta-alanine is rated "Possibly Effective" for Athletic performance (Natural Medicines).
  • Also on file: Beta-alanine is rated "Possibly Effective" for Physical performance.
  • Also on file: Cordyceps is rated "Possibly Ineffective" for Athletic performance.

The evidence for this product's ingredients is mixed. Beta-alanine is possibly effective for athletic performance and physical performance, though most other claimed uses (cognitive decline, COPD, cognitive function, menopausal symptoms) lack reliable evidence.

Alpha-GPC is possibly effective for Alzheimer disease but insufficient evidence supports its use for other cognitive conditions. For the mushroom extracts, the evidence we hold does not support their effectiveness for athletic performance or most cognitive uses—lion's mane, cordyceps, reishi, and shiitake all show insufficient reliable evidence or are rated possibly ineffective for their marketed purposes.

We hold no effectiveness data for NO3-T, L-citrulline, Hydromax, Peak02, Turkey Tail, or King Trumpet.

The evidence, ingredient by ingredient Beta-alanine Alpha-gpc Lion's Mane Mushroom Cordyceps Reishi Mushroom Shiitake Mushroom

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 6 of the 6 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 6.
  • General safety write-ups exist for 6 of 6.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Beta-alanine is generally well tolerated but commonly causes harmless skin tingling (paresthesia) and flushing—usually starting on the scalp within 20 minutes and lasting about an hour. This effect is dose-dependent and mild at lower doses.

The mushroom extracts are generally well tolerated short-term: lion's mane and cordyceps may cause gastrointestinal discomfort, nausea, or rash; reishi may cause dizziness, dry mouth, itching, nausea, or rash; shiitake may cause abdominal discomfort, bloating, diarrhea, nausea, or vomiting. Alpha-GPC is generally well tolerated but rarely associated with dizziness, headache, and insomnia; long-term use (2 months or more) has been rarely linked with elevated stroke risk.

Cordyceps is generally well tolerated for up to one year, though a rare case of liver inflammation has been reported. Beta-alanine, alpha-GPC, lion's mane, cordyceps, reishi, and shiitake all lack sufficient safety data in pregnancy and breastfeeding—the safety notes advise against use unless directed by your doctor or pharmacist.

Side effects, ingredient by ingredient Beta-alanine Alpha-gpc Lion's Mane Mushroom Cordyceps Reishi Mushroom Shiitake Mushroom

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 5 of the 6 matched ingredients can interact with medications — Cordyceps, Shiitake Mushroom, Reishi Mushroom, Alpha-gpc, Lion's Mane Mushroom.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 677 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking PUMP Cherry Burst, double-check with your pharmacist if you're on blood thinners (anticoagulants or antiplatelet drugs like warfarin or aspirin) — lion's mane, cordyceps, and reishi all increase bleeding risk. If you take blood pressure medications, diabetes medications, or immunosuppressants (including cyclosporine), the mushroom extracts in this blend may affect how they work.

Those on CYP2D6-metabolized drugs should also check — shiitake may slow the liver's processing of these medications. No interactions are documented in our data for the other ingredients we could check (beta-alanine and alpha-GPC).

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product targets athletes and those seeking cognitive support, with beta-alanine being the most evidence-backed ingredient for performance. However, if you take blood thinners, blood pressure medications, diabetes medications, or immunosuppressants, you need to check your exact medications before starting—the mushroom extracts carry documented interactions.

The tingling from beta-alanine is harmless but something to expect. Talk with your pharmacist before adding this to your routine, especially if you're pregnant, breastfeeding, or on any prescription medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 6 of 11 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about PUMP Cherry Burst, straight from the product label.

Brand Core Nutritionals
Barcode (UPC) 672975009502
Net contents 16.4 Oz(s); 464 Gram(s)
Market status On market
Date entered into DSLD Oct 24, 2023
DSLD ID 298348
Product type Other Combinations
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for PUMP Cherry Burst by Core Nutritionals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
23.2 Gram(s)
Maximum serving Sizes:
23.2 Gram(s)
Servings per container
20
UPC/BARCODE
672975009502
IngredientAmount% DV
Beta Alanine3200 mg, 1600 mg--
Alpha-Glycerylphosphorylcholine600 mg, 300 mg--
NO3-T2500 mg, 1250 mg--
L-Citruline6000 mg, 3000 mg--
Hydromax2000 mg, 1000 mg--
Peak022000 mg, 1000 mg--
Turkey Tail0 NP, 0 NP--
Lion's Mane0 NP, 0 NP--
Cordyceps0 NP, 0 NP--
Reishi0 NP, 0 NP--
Shiitake0 NP, 0 NP--
King Trumpet0 NP, 0 NP--

Other ingredients: Silicon Dioxide, Malic Acid, Citric Acid, Natural and Artificial flavor, Sucralose, Acesulfame Potassium

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

It should be simple: the right combination of specifically targeted ingredients for pump, endurance, strength, and focus all blended together to produce a scientifically sound, and complete, non-stimulant pre-workout. It should be, but it isn't. It is a good thing for consumers, then, that Core Nutritionals loves a challenge. With Core PUMP, we redefine the non-stimulant, pre-workout category with more than just a "pump" product. Core PUMP contains cutting edge and trademarked ingredients to maximize all performance aspects of your workout, without stimulants or jitters.

Core PUMP contains cutting edge and trademarked ingredients to maximize all performance aspects of your workout, without stimulants or jitters.

Full-spectrum non-stimulant pre-workout Pump Endurance Strength Focus

Manufactured in a U.S. cGMP facility.

Precautions

Warning: Consuming this product can expose you to chemicals including lead, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Warning: This product is only intended for use in healthy adults 18 years of age or older. Keep out of reach of children.

Pregnant or nursing women should not use this product. Consult your healthcare provider before using this product, especially if you are taking any prescription, over the counter medication, dietary supplement product, or if you have any pre-existing medical condition including but not limited to: high or low blood pressure, cardiac arrhythmia, stroke, heart, liver, kidney or thyroid disease, seizure disorder, psychiatric disease, diabetes, difficulty urinating due to prostate enlargement or if you are taking a MAOI (Monoamine Oxidase Inhibitor), PDE5 inhibitor, nitrates for chest pain, or any other medication.

Immediately discontinue use and consult your health care professional if you experience adverse reaction to this product. Do not exceed recommended serving. Do not use if safety seal is broken or missing.

Suggested/Recommended/Usage/Directions

Directions: Mix 2 scoops with 12-16 ounces of water and consume approximately 15-30 minutes prior to your workout.

Brand IP Statement(s)

Core Nutritionals Crush It!

NO3T Nitrate Technology NO3-T.COM/PATENTS NO3-T is a registered trademark of Thermolife International LLC, this mark covers the use of one or more patents listed at www.NO3-T.com/patents. HydroMax HydroMax is a registered trademark of Glanbia plc. PEAKO2 PeakO2 is a registered trademark of Compound Solutions, Inc.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formula

Cherry Burst Naturally & artificially flavored

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

PUMP Cherry Burst by Core Nutritionals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

PUMP Cherry Burst label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in PUMP Cherry Burst by Core Nutritionals

These are the 11 active ingredients this product is made of. Select any to open its full monograph.

Serving size23.2 Gram(s) Dosage formPowder Servings per container20 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Beta Alanine

No known
interactions
3200 mg per serving

Beta-alanine is an amino acid taken mostly by athletes to raise muscle carnosine, which may help buffer acid and reduce fatigue during short, high-int...

Beta Alanine monograph & interactions

Alpha-Glycerylphosphorylcholine

Interacts with
16 drugs
600 mg per serving

Alpha-GPC is a choline-containing compound used mainly for memory, brain health, and as a choline source. There is some evidence it may help cognition...

Alpha-Glycerylphosphorylcholine monograph & interactions

NO3-T

2500 mg per serving Form: Betaine Nitrate

L-Citruline

6000 mg per serving

Hydromax

2000 mg per serving Form: Glycerol, Powder

Peak02

2000 mg per serving

Other (inactive) ingredients: Silicon Dioxide, Malic Acid, Citric Acid, Natural and Artificial flavor, Sucralose, Acesulfame Potassium. These complete the product’s ingredient list but are not active constituents.

Interaction report

PUMP Cherry Burst by Core Nutritionals Drug Interactions

Want to check YOUR meds against PUMP Cherry Burst?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
677Drugs
654 Moderate 23 Minor

Ingredients driving the most interactions

Reishi 375
Lion's Mane 327
Shiitake 312
Cordyceps 249
Alpha-Glycerylphosphorylcholine 16

Individual Drug Interactions

The ingredients in PUMP Cherry Burst interact with 677 drugs. Click any drug to see the details.

5 of the 11 ingredients in PUMP Cherry Burst interact with drugs. Each result below shows which ingredient is responsible. Reishi Lion's Mane Shiitake Cordyceps Alpha-Glycerylphosphorylcholine

Each ingredient & the kinds of drugs it affects

For each ingredient in PUMP Cherry Burst with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Reishi3 drug types · 375 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
A dose of 1.5 grams daily of reishi mushroom does not seem to decrease platelet aggregation, but a higher dose of 3 grams daily does.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Animal research suggests that reishi mushroom decreases blood sugar. However, in patients with type 2 diabetes, taking reishi mushroom does not reduce fasting glucose levels, and its effects on glycated hemoglobin are inconsistent.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Reishi mushroom has shown hypotensive activity in animal research. Clinical evidence suggests that reishi mushroom reduces blood pressure in some, but not all, patients with hypertension.

Likelihood Possible Evidence D
Reishi full monograph & interactions

Lion's Mane3 drug types · 327 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, lion's mane mushroom may increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.
In vitro research suggests that lion's mane mushroom extracts can inhibit platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, lion's mane mushroom may have additive effects when used with antidiabetes drugs.
Animal research suggests that an aqueous extract of lion's mane mushroom can reduce serum glucose and increase serum insulin.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, concurrent use of lion's mane mushroom might interfere with immunosuppressive therapy.
In animal and in vitro research, lion's mane mushroom polysaccharides stimulate the immune system.

Likelihood Possible Evidence D
Lion's Mane full monograph & interactions

Shiitake2 drug types · 312 drugs

Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, shiitake mushroom might decrease levels of drugs metabolized by CYP2D6.
In vitro studies suggest that the shiitake mushroom extract AHCC might induce the CYP2D6 enzyme. This effect has not been reported in humans.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, taking shiitake mushroom might decrease the effects of immunosuppressive therapy.
In vitro evidence suggests that shiitake mushroom extracts stimulate immune function.

Likelihood Possible Evidence D
Shiitake full monograph & interactions

Cordyceps3 drug types · 249 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
In vitro and animal research suggests that cordyceps extract inhibits platelet aggregation and function. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Animal and in vitro research suggests that cordyceps stimulates the immune system. However, limited clinical research suggests that taking cordyceps may lower the necessary therapeutic dose of the immunosuppressant cyclosporine, which suggests that cordyceps may have an immunosuppressive effect.

Likelihood Possible Evidence B
Testosterone

Theoretically, concurrent use of cordyceps and testosterone might have additive effects.
Animal research suggests that cordyceps can increase testosterone levels. The clinical significance of this finding is unclear.

Likelihood Possible Evidence D
Cordyceps full monograph & interactions

Alpha-Glycerylphosphorylcholine1 drug type · 16 drugs

Scopolamine (Transderm Scop)

Theoretically, alpha-GPC might decrease the effects of scopolamine.
A small clinical study shows that alpha-GPC can partially counteract the attention and memory impairment effects caused by scopolamine given intramuscularly. Whether alpha-GPC can decrease the beneficial anti-motion sickness effects of the scopolamine patch (Transderm Scop) is unclear.

Likelihood Possible Evidence B
Alpha-Glycerylphosphorylcholine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for PUMP Cherry Burst, from the product label.

Core Nutritionals

See all Core Nutritionals products
Name
Core Nutritionals, LLC
City
Statesville
State
NC
ZipCode
28625
Phone Number
(888) 978-2332
Web Address
corenutritionals.com
Pharmacist Counseling Corner

PUMP Cherry Burst by Core Nutritionals: Common Questions

Does PUMP Cherry Burst by Core Nutritionals interact with any medications?
Yes. Based on its ingredients, PUMP Cherry Burst has a known interaction with 677 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
PUMP Cherry Burst contains 11 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will I feel that tingling everyone talks about with beta-alanine?
Probably, but it's harmless. Beta-alanine commonly causes skin flushing and a pins-and-needles feeling (paresthesia), usually starting on your scalp within 20 minutes and lasting about an hour. It's dose-dependent—the higher the dose, the more noticeable—and affects fewer people at lower doses.
Is this safe during pregnancy or while breastfeeding?
The safety data advises against it. Beta-alanine, alpha-GPC, lion's mane, cordyceps, reishi, and shiitake all lack enough safety information in pregnancy and breastfeeding. Talk with your doctor or pharmacist about whether this product is right for you in those situations.
What do the mushroom extracts in here actually do?
That's where the evidence gets thin. Most of these mushrooms—lion's mane, cordyceps, reishi, and shiitake—don't have solid evidence backing their use for athletic performance or cognitive function according to the data we hold. Some, like reishi and cordyceps, show little benefit for their marketed uses.
Can I take this if I'm on blood thinners?
Not without checking first. Lion's mane, cordyceps, and reishi all may increase bleeding risk when combined with blood thinners. Your pharmacist can tell you whether it's safe with your specific medication.
What are the main side effects I should watch for?
Beyond the expected tingling from beta-alanine, the mushroom extracts may cause mild gastrointestinal upset, nausea, dizziness, or rash in some people. These are generally uncommon. Alpha-GPC rarely causes headache or insomnia, and very long-term use has been linked to stroke risk in rare cases.
Does this product have any fillers?
Yes, it contains several inactive ingredients including silicon dioxide, malic acid, citric acid, natural and artificial flavoring, and artificial sweeteners (sucralose and acesulfame potassium).

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if PUMP Cherry Burst is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

PUMP Cherry Burst label
Go deeper

The Full Monographs Behind PUMP Cherry Burst’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Beta-alanine

Beta-alanine is an amino acid taken mostly by athletes to raise muscle carnosine, which may help buffer acid and reduce fatigue during short, high-intensity exercise. The evidence is moderat...

Read the full Beta-alanine monograph → Herb & supplement monograph

Alpha-gpc

Interacts with 16 drugs

Alpha-GPC is a choline-containing compound used mainly for memory, brain health, and as a choline source. There is some evidence it may help cognition in people with dementia, but evidence i...

Read the full Alpha-gpc monograph → Herb & supplement monograph

Lion's Mane Mushroom

Interacts with 327 drugs

Lion's mane is an edible mushroom that is popular as a 'nootropic' for memory, focus, and nerve health, but solid human evidence is still limited and early. It is generally well tolerated as...

Read the full Lion's Mane Mushroom monograph → Herb & supplement monograph

Cordyceps

Interacts with 249 drugs

Cordyceps is a fungus used in traditional Chinese medicine for energy, exercise performance, and lung and immune support. Human research is limited and mostly low quality, so its benefits ar...

Read the full Cordyceps monograph → Herb & supplement monograph

Reishi Mushroom

Interacts with 375 drugs

Reishi is a traditional Asian mushroom widely used to support the immune system and overall wellness. Human evidence for most of its claimed benefits is limited or low-quality, so it should...

Read the full Reishi Mushroom monograph → Herb & supplement monograph

Shiitake Mushroom

Interacts with 312 drugs

Shiitake is a popular edible mushroom that is nutritious and safe to eat as food for most people. Some of its extracts (like lentinan and AHCC) have been studied as immune support, mainly al...

Read the full Shiitake Mushroom monograph →
Sources

Sources & How We Checked

PUMP Cherry Burst's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 121 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Beta-alanine 13 references
  1. Harris RC, Tallon MJ, Dunnett M, et al. The absorption of orally supplied beta-alanine and its effect on muscle carnosine synthesis in human vastus lateralis. Amino Acids 2006;30:279-89.
  2. Hill CA, Harris RC, Kim HJ, et al. Influence of beta-alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity. Amino Acids 2007;32:225-33.
  3. Bellinger PM, Minahan CL. The effect of ß-alanine supplementation on cycling time trials of different length. Eur J Sport Sci 2016;16(7):829-36.
  4. Chung W, Shaw G, Anderson ME, et al. Effect of 10 week beta-alanine supplementation on competition and training performance in elite swimmers. Nutrients 2012;4(10):1441-53. PubMed
  5. Glenn JM, Gray M, Stewart R, et al. Incremental effects of 28 days of beta-alanine supplementation on high-intensity cycling performance and blood lactate in masters female cyclists. Amino Acids 2015;47(12):2593-600. PubMed
  6. Gross M, Bieri K, Hoppeler H, Norman B, Vogt M. Beta-alanine supplementation improves jumping power and affects severe-intensity performance in professional alpine skiers. Int J Sport Nutr Exerc Metab 2014;24(6):665-73. PubMed
  7. Howe ST, Bellinger PM, Driller MW, Shing CM, Fell JW. The effect of beta-alanine supplementation on isokinetic force and cycling performance in highly trained cyclists. Int J Sport Nutr Exerc Metab 2013;23(6):562-70. PubMed
  8. Sweeney KM, Wright GA, Glenn Brice A, Doberstein ST. The effect of beta-alanine supplementation on power performance during repeated sprint activity. J Strength Cond Res 2010;24(1):79-87.
  9. Décombaz J, Beaumont M, Vuichoud J, Bouisset F, Stellingwerff T. Effect of slow-release ß-alanine tablets on absorption kinetics and paresthesia. Amino Acids 2012;43(1):67-76. Erratum in: Amino Acids 2013;45(4):1015.
  10. Stellingwerff T, Anwander H, Egger A, et al. Effect of two ß-alanine dosing protocols on muscle carnosine synthesis and washout. Amino Acids 2012;42(6):2461-72. PubMed
  11. da Silva RP, de Oliveira LF, Saunders B, et al. Effects of ß-alanine and sodium bicarbonate supplementation on the estimated energy system contribution during high-intensity intermittent exercise. Amino Acids. 2019;51(1):83-96. PubMed
  12. Varanoske AN, Hoffman JR, Church DD, et al. Comparison of sustained-release and rapid-release ß-alanine formulations on changes in skeletal muscle carnosine and histidine content and isometric performance following a muscle-damaging protocol. Amino Acids. PubMed
  13. Perim P, Gobbi N, Duarte B, et al. Beta-alanine did not improve high-intensity performance throughout simulated road cycling. Eur J Sport Sci 2021. PubMed

See these in context on the Beta-alanine monograph →

Alpha-gpc 4 references
  1. Di Perri R, Coppola G, Ambrosio LA, et al. A multicentre trial to the evaluate the efficacy and tolerability of alpha-glycerylphosphorylcholine versus cytosine diphosphocholine in patients with vascular dementia. J Int Med Res 1991;19:330-41.
  2. Barbagallo Sangiorgi G, Barbagallo M, Giordano M, et al. Alpha-glycerophosphocholine in the mental recovery of cerebral ischemic attacks: An Italian multicenter clinical trial. Ann N Y Acad Sci 1994;717:253-69. PubMed
  3. Canal N, Franceschi M, Alberoni M, et al. Effect of L-alpha-glyceryl-phosphorylcholine on amnesia caused by scopolamine. Int J Clin Pharmacol Ther Toxicol 1991;29:103-7.
  4. Lee G, Choi S, Chang J, et al. Association of L-a glycerylphosphorylcholine with subsequent stroke risk after 10 Years. JAMA Netw Open 2021;4(11):e2136008.

See these in context on the Alpha-gpc monograph →

Lion's Mane Mushroom 6 references
  1. Product information for <em>Niaspan</em>. Abbott Laboratories. North Chicago, IL 60064. April 2015.
  2. Liang B, Guo Z, Xie F, Zhao A. Antihyperglycemic and antihyperlipidemic activities of aqueous extract of Hericium erinaceus in experimental diabetic rats. BMC Complement Altern Med. 2013;13:253. PubMed
  3. Mori K, Inatomi S, Ouchi K, Azumi Y, Tuchida T. Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trial. Phytother Res. 2009;23(3):367-72.
  4. Mori K, Kikuchi H, Obara Y, et al. Inhibitory effect of hericenone B from Hericium erinaceus on collagen-induced platelet aggregation. Phytomedicine. 2010;17(14):1082-5. PubMed
  5. Li IC, Chang HH, Lin CH, et al. Prevention of early Alzheimer's disease by erinacine A-enriched Hericium erinaceus mycelia pilot double-blind placebo-controlled study. Front Aging Neurosci 2020 Jun 3;12:155. doi: 10.3389/fnagi.2020.00155. PubMed
  6. Tian B, Liu R, Xu T, et al. Modulating effects of Hericium erinaceus polysaccharides on the immune response by regulating gut microbiota in cyclophosphamide-treated mice. J Sci Food Agric 2023;103(6):3050-3064.

See these in context on the Lion's Mane Mushroom monograph →

Cordyceps 14 references
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Reishi Mushroom 17 references
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Shiitake Mushroom 67 references
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