Interactions on record — worth a quick check against your medications. Based on 3 of 7 ingredients. Check your meds →
Dietary supplement

PUMP Pink Lemonade Ingredients & Drug Interactions

by Core Nutritionals

Powder Category: Other Combinations
Most serious interaction: Minor
The interaction bottom line Most serious interaction: Minor

PUMP Pink Lemonade is a dietary supplement by Core Nutritionals with 7 active ingredients. Its ingredients are commonly taken for memory and learning support, age-related cognitive decline, alzheimer's disease and dementia (under study).Based on those ingredients, 16 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Alpha-Glycerylphosphorylcholine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of PUMP Pink Lemonade by Core Nutritionals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 7 of its 7 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

PUMP Pink Lemonade contains 7 active ingredients designed to support workout performance and blood flow. Alpha-glycerylphosphorylcholine (alpha-GPC) is included for potential cognitive support.

Glycerol (HydroPrime) and Beta Alanine are both used for athletic performance. The product also contains AstraGin, NO3-T, and L-Citruline—three ingredients we cannot verify for interactions.

The powder also holds inactive ingredients: silicon dioxide, citric acid, natural and artificial flavors, sucralose, red beet, and acesulfame potassium.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: pump endurance strength and focus non-stimulant pre-workout.
  • We looked for evidence on: Athletic performance, Physical performance, Exercise-induced muscle breakdown, muscle endurance, workout performance, exercise capacity — and 1 related terms.
  • The strongest evidence on file: Glycerol is rated "Possibly Effective" for Athletic performance (Natural Medicines).
  • Also on file: Beta-alanine is rated "Possibly Effective" for Athletic performance, Physical performance.
  • Also on file: Beta-alanine is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced muscle breakdown.

Alpha-GPC is possibly effective for Alzheimer disease, but evidence for brain tumor, cognitive function, vascular dementia, and stroke is insufficient. Glycerol is likely effective for constipation and possibly effective for athletic performance, though it's likely ineffective for meningitis, prematurity, and stroke.

Beta Alanine is possibly effective for athletic and physical performance, but evidence for age-related cognitive decline, COPD, cognitive function, and menopausal symptoms is insufficient. For the three ingredients we could not check—AstraGin, NO3-T, and L-Citruline—effectiveness data is not on file.

The evidence, ingredient by ingredient Alpha-gpc Glycerol Beta-alanine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Alpha-GPC is generally well tolerated, though long-term safety isn't fully established. Rare side effects include dizziness, excitation, headache, insomnia, diarrhea, heartburn, nausea, and vomiting.

Stroke has been rarely reported with oral use of at least 2 months compared to non-users. Glycerol is generally well tolerated in normal amounts, but large doses can cause stomach upset and dehydration concerns.

Common side effects are bloating, diarrhea, nausea, vomiting, dizziness, and headache. Beta Alanine is generally well tolerated but commonly causes harmless skin tingling (paresthesias) and flushing, usually starting on the scalp within 20 minutes and lasting about an hour—severity depends on dose.

Pregnancy and lactation data is insufficient for both alpha-GPC and beta-alanine; talk to your doctor before use if you're pregnant or nursing. Glycerol safety data in pregnancy and lactation is also limited.

Side effects, ingredient by ingredient Alpha-gpc Glycerol Beta-alanine

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 3 matched ingredients can interact with medications — Alpha-gpc.
  • The most serious interaction on file is rated Minor.
  • For scale: 16 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you use the Transderm Scop motion-sickness patch, flag it with your pharmacist—alpha-GPC in this product may affect its effectiveness. No other medication interactions are documented for the ingredients we could check, but three ingredients (AstraGin, NO3-T, L-Citruline) have no interaction data on file.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

PUMP Pink Lemonade is mainly designed for athletic performance and workout support. If you take a scopolamine motion-sickness patch, check with your pharmacist before adding this product.

Otherwise, it's generally well tolerated, though expect possible tingling and flushing from beta-alanine. Run your medications through the checker on this page to be sure.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 7 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about PUMP Pink Lemonade, straight from the product label.

Brand Core Nutritionals
Barcode (UPC) 850051031122
Net contents 15.2 Ounce(s); 432 Gram(s)
Market status On market
Date entered into DSLD Nov 22, 2024
DSLD ID 320921
Product type Other Combinations
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for PUMP Pink Lemonade by Core Nutritionals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
21.6 Gram(s)
Maximum serving Sizes:
21.6 Gram(s)
Servings per container
20
UPC/BARCODE
850051031122
IngredientAmount% DV
Alpha-Glycerylphosphorylcholine300 mg, 600 mg--
AstraGin25 mg, 50 mg--
NO3-T1250 mg, 2500 mg--
L-Citruline3000 mg, 6000 mg--
HydroPrime1000 mg, 2000 mg--
315749127 mg, 254 mg--
Beta Alanine1600 mg, 3200 mg--

Other ingredients: Silicon Dioxide, Citric Acid, Natural and Artificial flavors, Sucralose, Red Beet, Acesulfame Potassium

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

It should be simple: the right combination of specifically targeted ingredients for pump, endurance, strength, and focus all blended together to produce a scientifically sound, and complete, non-stimulant pre-workout. It should be, but it isn't. It is a good thing for consumers, then, that Core Nutritionals loves a challenge. With Core PUMP, we redefine the non-stimulant, pre-workout category with more than just a "pump" product. Core PUMP contains cutting edge and trademarked ingredients to maximize all performance aspects of your workout, without stimulants or jitters.

Pink Lemonade Naturally & artificially flavored Dietary Supplement

Precautions

Warning: Consuming this product can expose you to chemicals including lead, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Warning: This product is only intended for use in healthy adults 18 years of age or older.

Pregnant or nursing women should not use this product. Consult your healthcare provider before using this product, especially if you are taking any prescription, over the counter medication, dietary supplement product, or if you have any pre-existing medical condition including but not limited to: high or low blood pressure, cardiac arrhythmia, stroke, heart, liver, kidney or thyroid disease, seizure disorder, psychiatric disease, diabetes, difficulty urinating due to a prostate enlargement or if you are taking a MAOI (Monoamine Oxidase Inhibitor), PDE5 inhibitor, nitrates for chest pain, or any other medication.

Immediately discontinue use and consult your health care professional if you experience adverse reaction to this product. Do not exceed recommended serving. Do not use if safety seal is broken or missing.

Keep out of reach of children.

Allergens: Contains milk. Manufactured in a facility that also process ingredients containing milk, eggs, fish, shellfish, tree nuts, peanut, wheat, sesame, and soy.

Suggested/Recommended/Usage/Directions

Directions: Mix 2 scoops with 12-16 ounces of water and consume approximately 15-30 minutes prior to your workout.

Brand IP Statement(s)

Core Nutritionals Crush it!

NO3T Nitrate Technology NO3-T.com/Patents NO3-T is a registered trademark of ThermoLife International LLC, this mark covers the use of one or more patents listed at www.NO3-T.com/patents VasoDrive-AP VasoDrive-AP is the registered trademark of Nova Nutra LLC AstraGin AstraGin is a registered trademark of NuLiv Science USA Inc. HydroPrime HydroPrime is a trademark of NNB Nutrition

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Doeaja

Servings per container: 20 (40 scoops)

Formulation

Full-Spectrum Non-Stimulant Pre-Workout Pump Endurance Strength Focus

Manufactured in a U.S. cGMP facility

FDA Statement of Identity

Pink Lemonade Naturally & artificially flavored Dietary Supplement

See for yourself

PUMP Pink Lemonade by Core Nutritionals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in PUMP Pink Lemonade by Core Nutritionals

These are the 7 active ingredients this product is made of. Select any to open its full monograph.

Serving size21.6 Gram(s) Dosage formPowder Servings per container20 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Alpha-Glycerylphosphorylcholine

Interacts with
16 drugs
300 mg per serving

Alpha-GPC is a choline-containing compound used mainly for memory, brain health, and as a choline source. There is some evidence it may help cognition...

Alpha-Glycerylphosphorylcholine monograph & interactions

AstraGin

25 mg per serving Form: Astragalus membranaceus root extract, Panax notoginseng root extract

NO3-T

1250 mg per serving Form: Betaine Nitrate

L-Citruline

3000 mg per serving

HydroPrime

No known
interactions
1000 mg per serving Form: Glycerol

Glycerol (glycerin) is a sweet, syrupy compound made naturally in the body and widely used in foods, skin products, and medicines. It is well establis...

HydroPrime monograph & interactions

315749

127 mg per serving Form: Casein, Hydrolyzed

Beta Alanine

No known
interactions
1600 mg per serving

Beta-alanine is an amino acid taken mostly by athletes to raise muscle carnosine, which may help buffer acid and reduce fatigue during short, high-int...

Beta Alanine monograph & interactions

Other (inactive) ingredients: Silicon Dioxide, Citric Acid, Natural and Artificial flavors, Sucralose, Red Beet, Acesulfame Potassium. These complete the product’s ingredient list but are not active constituents.

Interaction report

PUMP Pink Lemonade by Core Nutritionals Drug Interactions

Want to check YOUR meds against PUMP Pink Lemonade?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
16Drugs
16 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in PUMP Pink Lemonade with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Alpha-Glycerylphosphorylcholine1 drug type · 16 drugs

Scopolamine (Transderm Scop)

Theoretically, alpha-GPC might decrease the effects of scopolamine.
A small clinical study shows that alpha-GPC can partially counteract the attention and memory impairment effects caused by scopolamine given intramuscularly. Whether alpha-GPC can decrease the beneficial anti-motion sickness effects of the scopolamine patch (Transderm Scop) is unclear.

Likelihood Possible Evidence B
The maker

Brand information

Manufacturer and brand details for PUMP Pink Lemonade, from the product label.

Core Nutritionals

See all Core Nutritionals products
Name
Core Nutritionals, LLC
City
Statesville
State
NC
ZipCode
28625
Phone Number
(888) 978-2332
Web Address
corenutritionals.com
Pharmacist Counseling Corner

PUMP Pink Lemonade by Core Nutritionals: Common Questions

Does PUMP Pink Lemonade by Core Nutritionals interact with any medications?
Yes. Based on its ingredients, PUMP Pink Lemonade has a known interaction with 16 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
PUMP Pink Lemonade contains 7 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this give me that tingling feeling I've heard about pre-workouts causing?
Beta-alanine in this product commonly causes harmless skin tingling and flushing. It usually starts on your scalp about 20 minutes after you take it, spreads across your body, and lasts roughly an hour. How intense it is depends on the dose—it can be very mild, tolerable, or stronger. Some people don't feel it at all at lower doses.
Is PUMP safe if I'm pregnant or breastfeeding?
There isn't enough safety data for alpha-GPC or beta-alanine during pregnancy or breastfeeding. Talk to your doctor or pharmacist before using this product if you're pregnant, planning pregnancy, or nursing—they can give you personalized advice.
Does alpha-GPC in this really help with brain function?
Alpha-GPC is possibly effective for Alzheimer disease based on available evidence. For general cognitive function, brain tumors, vascular dementia, and stroke, the evidence is insufficient to draw firm conclusions.
What's the glycerol (HydroPrime) in here supposed to do?
Glycerol is likely effective for athletic performance and constipation. In this product it's included to support workout performance and hydration.
Could this upset my stomach?
Yes—glycerol in larger amounts can cause bloating, diarrhea, nausea, vomiting, and dizziness. Large doses also raise dehydration concerns. Start with the recommended serving to see how you tolerate it.
I use a motion-sickness patch. Can I still take this?
Check with your pharmacist first. Alpha-GPC in this product may reduce how well the scopolamine patch (Transderm Scop) works, though the full effect isn't clear. Your pharmacist can advise whether it's right for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if PUMP Pink Lemonade is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

PUMP Pink Lemonade label
Sources

Sources & How We Checked

PUMP Pink Lemonade's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 25 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Alpha-gpc 4 references
  1. Di Perri R, Coppola G, Ambrosio LA, et al. A multicentre trial to the evaluate the efficacy and tolerability of alpha-glycerylphosphorylcholine versus cytosine diphosphocholine in patients with vascular dementia. J Int Med Res 1991;19:330-41.
  2. Barbagallo Sangiorgi G, Barbagallo M, Giordano M, et al. Alpha-glycerophosphocholine in the mental recovery of cerebral ischemic attacks: An Italian multicenter clinical trial. Ann N Y Acad Sci 1994;717:253-69. PubMed
  3. Canal N, Franceschi M, Alberoni M, et al. Effect of L-alpha-glyceryl-phosphorylcholine on amnesia caused by scopolamine. Int J Clin Pharmacol Ther Toxicol 1991;29:103-7.
  4. Lee G, Choi S, Chang J, et al. Association of L-a glycerylphosphorylcholine with subsequent stroke risk after 10 Years. JAMA Netw Open 2021;4(11):e2136008.

See these in context on the Alpha-gpc monograph →

Glycerol 8 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Wagner DR. Hyperhydrating with glycerol: implications for athletic performance. J Am Diet Assoc 1999;99:207-12. PubMed
  3. Yu YL, Kumana CR, Lauder IJ, et al. Treatment of acute cortical infarct with intravenous glycerol. A double-blind, placebo-controlled randomized trial. Stroke 1993;24:1119-24. PubMed
  4. Frei A, Cottier C, Wunderlich P, Ludin E. Glycerol and dextran combined in the therapy of acute stroke. A placebo-controlled, double-blind trial with a planned interim analysis. Stroke 1987;18:373-9. PubMed
  5. Balaskas E, Szepietowski JC, Bessis D, Ioannides D, Ponticelli C, Ghienne C, Taberly A, Dupuy P. Randomized, double-blind study with glycerol and paraffin in uremic xerosis. Clin J Am Soc Nephrol. 2011 Apr;6(4):748-52. PubMed
  6. Blanchet-Bardon C, Tadini G, Machado Matos M, Delarue A. Association of glycerol and paraffin in the treatment of ichthyosis in children: an international, multicentric, randomized, controlled, double-blind study. J Eur Acad Dermatol Venereol. 2012 Aug;26 PubMed
  7. Kajita N, Kanamori K, Yamamoto S, Yoshida K. Generalized Urticaria Caused by a Glycerin Enema in an Infant. J Investig Allergol Clin Immunol 2022;32(4):318-319. PubMed
  8. Suzuki R, Fukuyama K, Miyazaki Y, Namiki T. Contact urticaria syndrome and protein contact dermatitis caused by glycerin enema. JAAD Case Reports. 2016;2:108-10. PubMed

See these in context on the Glycerol monograph →

Beta-alanine 13 references
  1. Harris RC, Tallon MJ, Dunnett M, et al. The absorption of orally supplied beta-alanine and its effect on muscle carnosine synthesis in human vastus lateralis. Amino Acids 2006;30:279-89.
  2. Hill CA, Harris RC, Kim HJ, et al. Influence of beta-alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity. Amino Acids 2007;32:225-33.
  3. Bellinger PM, Minahan CL. The effect of ß-alanine supplementation on cycling time trials of different length. Eur J Sport Sci 2016;16(7):829-36.
  4. Chung W, Shaw G, Anderson ME, et al. Effect of 10 week beta-alanine supplementation on competition and training performance in elite swimmers. Nutrients 2012;4(10):1441-53. PubMed
  5. Glenn JM, Gray M, Stewart R, et al. Incremental effects of 28 days of beta-alanine supplementation on high-intensity cycling performance and blood lactate in masters female cyclists. Amino Acids 2015;47(12):2593-600. PubMed
  6. Gross M, Bieri K, Hoppeler H, Norman B, Vogt M. Beta-alanine supplementation improves jumping power and affects severe-intensity performance in professional alpine skiers. Int J Sport Nutr Exerc Metab 2014;24(6):665-73. PubMed
  7. Howe ST, Bellinger PM, Driller MW, Shing CM, Fell JW. The effect of beta-alanine supplementation on isokinetic force and cycling performance in highly trained cyclists. Int J Sport Nutr Exerc Metab 2013;23(6):562-70. PubMed
  8. Sweeney KM, Wright GA, Glenn Brice A, Doberstein ST. The effect of beta-alanine supplementation on power performance during repeated sprint activity. J Strength Cond Res 2010;24(1):79-87.
  9. Décombaz J, Beaumont M, Vuichoud J, Bouisset F, Stellingwerff T. Effect of slow-release ß-alanine tablets on absorption kinetics and paresthesia. Amino Acids 2012;43(1):67-76. Erratum in: Amino Acids 2013;45(4):1015.
  10. Stellingwerff T, Anwander H, Egger A, et al. Effect of two ß-alanine dosing protocols on muscle carnosine synthesis and washout. Amino Acids 2012;42(6):2461-72. PubMed
  11. da Silva RP, de Oliveira LF, Saunders B, et al. Effects of ß-alanine and sodium bicarbonate supplementation on the estimated energy system contribution during high-intensity intermittent exercise. Amino Acids. 2019;51(1):83-96. PubMed
  12. Varanoske AN, Hoffman JR, Church DD, et al. Comparison of sustained-release and rapid-release ß-alanine formulations on changes in skeletal muscle carnosine and histidine content and isometric performance following a muscle-damaging protocol. Amino Acids. PubMed
  13. Perim P, Gobbi N, Duarte B, et al. Beta-alanine did not improve high-intensity performance throughout simulated road cycling. Eur J Sport Sci 2021. PubMed

See these in context on the Beta-alanine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring