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Dietary supplement

Pumpkin Seed Oil 1,000 mg Ingredients & Drug Interactions

by Swanson

Softgel Capsule Category: Fat/fatty Acid
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Pumpkin Seed Oil 1,000 mg is a dietary supplement by Swanson with 1 active ingredient. Its ingredients are commonly taken for benign prostatic hyperplasia (bph) symptoms, overactive bladder, eye and skin health (vitamin a source).Based on those ingredients, 1 medication has a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Pumpkin seed Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Pumpkin Seed Oil 1,000 mg by Swanson

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Partial disclosure
Ingredient Transparency · database check
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 2 of its 3 active ingredients.

This product contains 3 active ingredients: pumpkin seed oil as the main component, plus polyunsaturated fat and monounsaturated fat. The supplement also contains gelatin, glycerin, and purified water as inactive ingredients that make up the softgel capsule.

Pumpkin seed oil is a concentrated oil extracted from pumpkin seeds, delivered at 1,000 mg per softgel.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: supports cardiovascular health blood sugar and prostate health.
  • We looked for evidence on: Benign prostatic hyperplasia (BPH), Overactive bladder, cognitive function, brain development.
  • The strongest evidence on file: Pumpkin is rated "Possibly Effective" for Benign prostatic hyperplasia (BPH) (Natural Medicines).
  • Also on file: Pumpkin is rated "Insufficient Reliable Evidence To Rate" for Overactive bladder.

Pumpkin seed oil is possibly effective for benign prostatic hyperplasia (BPH) — enlarged prostate gland that affects urination. For other uses — hair loss (androgenic alopecia), bladder inflammation (interstitial cystitis), parasitic infections, and urinary tract infections — the evidence isn't established in the data we hold.

The evidence, ingredient by ingredient Pumpkin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Orally, pumpkin seed oil is generally well tolerated in adults. The most common side effects from clinical trials and reports are mild abdominal discomfort, diarrhea, nausea, and vomiting.

Rarely, anaphylaxis (a severe allergic reaction) has been reported. There are also two case reports of people experiencing substantial hair loss or severe nausea, vomiting, and diarrhea after eating bitter-tasting pumpkin or squash with high concentrations of cucurbitacin — a compound found in wild pumpkins — though this product is from cultivated pumpkin seed oil and would not typically contain that.

Pregnancy and lactation safety data aren't well studied for concentrated pumpkin seed supplements. Talk with your doctor or pharmacist about whether this product is right for you if you're pregnant or breastfeeding.

Side effects, ingredient by ingredient Pumpkin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Pumpkin.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: lithium.
  • For scale: 1 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take lithium (a mood-disorder medication), this is the main one to flag before starting: pumpkin seed oil may increase lithium levels in your blood. Check with your doctor or pharmacist before adding this supplement to your routine.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glancePartially disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Pumpkin seed oil may help with enlarged prostate symptoms. If you take lithium, check with your doctor or pharmacist before starting — the supplement might affect how your body clears the medication.

For most other people, it's generally well tolerated, though mild digestive upset can happen. Discuss this supplement with your own healthcare provider, especially if you're on any regular medications or if you're pregnant or nursing.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 21, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pumpkin Seed Oil 1,000 mg, straight from the product label.

Brand Swanson
Barcode (UPC) 087614013640
Net contents 100 Softgel(s)
Market status On market
Date entered into DSLD Jul 21, 2022
DSLD ID 266956
Product type Fat/fatty Acid
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pumpkin Seed Oil 1,000 mg by Swanson, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
100
UPC/BARCODE
087614013640
IngredientAmount% DV
Calories10 Calorie(s)--
Polyunsaturated Fat0.5 Gram(s)--
Monounsaturated Fat0 Gram(s)--
Total Fat1 Gram(s)1%
Saturated Fat0 Gram(s)--
Trans Fat0 Gram(s)--
Pumpkin seed Oil1 Gram(s)--

Other ingredients: Gelatin, Glycerin, Water, Purified

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

swanson.com or call 1-800-437-4148

Science-Backed Quality Since 1969

Formulation

Supports cardiovascular health and blood sugar metabolism Supports cognitive function and healthy brain development Maintains prostate health

Heart and Brain Health

1,000 mg per softgel

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take one softgel one to two times per day with water.

Precautions

Warning: For adults only.

Consult your healthcare provider before using this or any product if you are pregnant or nursing, taking medication, or have a medical condition.

Keep out of reach of children.

Storage

Store in a cool, dry place. Do not refrigerate.

FDA Disclaimer Statement

These statement have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

See for yourself

Pumpkin Seed Oil 1,000 mg by Swanson label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Pumpkin Seed Oil 1,000 mg by Swanson

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container100 Amounts shown are per serving.

Pumpkin seed Oil

Interacts with
1 drug
1 Gram(s) per serving

Pumpkin is a nutritious squash, and its seeds and seed oil are the parts most often used as supplements, mainly for urinary and prostate symptoms. The...

Pumpkin seed Oil monograph & interactions

Other (inactive) ingredients: Gelatin, Glycerin, Water, Purified. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pumpkin Seed Oil 1,000 mg by Swanson Drug Interactions

Want to check YOUR meds against Pumpkin Seed Oil 1,000 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
1Drugs
1 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Pumpkin Seed Oil 1,000 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Pumpkin seed Oil1 drug type · 1 drug

Lithium

Pumpkin might reduce excretion and increase levels of lithium.
Pumpkin is thought to have diuretic properties. Theoretically, this might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
The maker

Brand information

Manufacturer and brand details for Pumpkin Seed Oil 1,000 mg, from the product label.

Swanson

See all Swanson products
Name
Swanson Health Products
City
Fargo
State
ND
ZipCode
58104
Phone Number
1-800-437-4148
Web Address
swanson.com
Pharmacist Counseling Corner

Pumpkin Seed Oil 1,000 mg by Swanson: Common Questions

Does Pumpkin Seed Oil 1,000 mg by Swanson interact with any medications?
Yes. Based on its ingredients, Pumpkin Seed Oil 1,000 mg has a known interaction with 1 medication. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Pumpkin Seed Oil 1,000 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is this pumpkin seed oil supposed to help with?
The strongest evidence supports its use for benign prostatic hyperplasia — that's an enlarged prostate gland that can affect urination in older men. For hair loss, bladder inflammation, parasitic infections, and UTIs, there isn't enough reliable evidence yet to know if it works.
What side effects might I get?
Most people tolerate it well. The common ones from trials are mild abdominal discomfort, diarrhea, nausea, and vomiting. Rarely, severe allergic reaction has been reported. If the pumpkin seed oil came from a wild or bitter-tasting pumpkin with high toxin levels, hair loss or severe stomach upset could happen — but this product is from cultivated pumpkin seeds, so that risk is very low.
Is it safe to use during pregnancy or while breastfeeding?
There isn't enough study data on concentrated pumpkin seed supplements in pregnancy or breastfeeding. Talk with your doctor or pharmacist for personalized advice before taking it.
I take lithium. Is this safe for me?
Not without checking first. Pumpkin seed oil may slow how your body clears lithium and raise its levels, which could be a problem. Talk with your doctor or pharmacist about whether this supplement is right for you and whether your lithium dose needs to change.
What's in the capsule besides pumpkin seed oil?
The softgel shell is made from gelatin and glycerin, with purified water. There are also polyunsaturated and monounsaturated fats as active ingredients in the formulation.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pumpkin Seed Oil 1,000 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pumpkin Seed Oil 1,000 mg label
Go deeper

The Full Monographs Behind Pumpkin Seed Oil 1,000 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Pumpkin Seed Oil 1,000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Pumpkin 5 references
  1. Marks L, Partin AW, Epstein JI, et al. Effects of a saw palmetto herbal blend in men with symptomatic benign prostatic hyperplasia. J Urol 2000;163:1451-6. DOI
  2. Cho YH, Lee SY, Jeong DW, et al. Effect of pumpkin seed oil on hair growth in men with androgenetic alopecia: a randomized, double-blind, placebo-controlled trial. Evid Based Complement Alternat Med 2014;2014:549721. PubMed
  3. Vahlensieck W, Theurer C, Pfitzer E, Patz B, Banik N, Engelmann U. Effects of pumpkin seed in men with lower urinary tract symptoms due to benign prostatic hyperplasia in the one-year, randomized, placebo-controlled GRANU study. Urol Int 2015;94(3):286-95 PubMed
  4. Assouly P. Hair loss associated with cucurbit poisoning. JAMA Dermatol. 2018 May 1;154(5):617-618. PubMed
  5. Gawryjolek J, Ludwig H, Zbikowska-Götz M, Bartuzi Z, Krogulska A. Anaphylaxis after consumption of pumpkin seeds in a 2-y-old child tolerant to its pulp: A case study. Nutrition 2021;89:111272. PubMed

See these in context on the Pumpkin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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