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Dietary supplement

PEAK ATP 400 mg Ingredients & Drug Interactions

by Swanson

PEAK ATP 400 mg label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking PEAK ATP 400 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

PEAK ATP 400 mg is a dietary supplement by Swanson with 1 active ingredient. Its ingredients are commonly taken for energy and cellular function support, athletic performance and muscle energy, circulation support.Based on those ingredients, 47 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Peak ATP. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against PEAK ATP 400 mg by Swanson

Ask about any prescription or over-the-counter medication and we check it for interactions with PEAK ATP 400 mg by Swanson — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of PEAK ATP 400 mg by Swanson

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Peak ATP 400 mg contains one active ingredient: adenosine (also called Peak ATP), an energy molecule your cells naturally produce. The capsule also holds inactive ingredients—hypromellose, rice flour, and calcium laurate—which are binders and fillers that help form and stabilize the supplement.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: supports physical energy and healthy circulation.
  • We looked for evidence on: Athletic performance, Cardiovascular disease diagnosis, Cellular energy, Exercise performance, Blood flow.
  • The strongest evidence on file: Adenosine is rated "Effective" for Cardiovascular disease diagnosis (Natural Medicines).
  • Also on file: Adenosine is rated "Insufficient Reliable Evidence To Rate" for Athletic performance.

Adenosine is rated effective for paroxysmal supraventricular tachycardia (a sudden, fast heart rhythm that starts in the upper chambers) and for cardiovascular disease diagnosis (such as during stress testing). These ratings apply to the prescription injectable form used in medical settings.

The evidence supporting oral supplement use is limited, so effectiveness claims for this capsule form rest on limited data.

The evidence, ingredient by ingredient Adenosine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

The safety information we have is based primarily on adenosine's prescription injectable form, which is powerful and must only be given by medical professionals. For the oral supplement form in this product, a thorough safety evaluation has not been conducted.

The intravenous prescription form can cause chest pain, dizziness, shortness of breath, facial flushing, headache, low blood pressure, nausea, and other effects; rare serious effects include abnormal heart rhythms and cardiac arrest. When adenosine is taken by mouth or injection into muscle, no adverse effects have been reported, but comprehensive safety data is lacking.

The safety data advises against use during breastfeeding due to insufficient information.

Side effects, ingredient by ingredient Adenosine

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Adenosine.
  • The most serious interaction on file is rated Major.
  • For scale: 47 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Peak ATP, check if you take dipyridamole (Persantine)—adenosine can strengthen both its effects and risks, potentially causing fainting and slow heart rate. Also check for carbamazepine (Tegretol), which may increase heart block risk when combined with adenosine.

Avoid methylxanthines—caffeine, aminophylline, and theophylline—for 24 hours before taking this product, as they can block adenosine's effects. Use the medication checker on this page to search your exact prescriptions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

Peak ATP is marketed for cardiovascular support, though oral supplement evidence is limited. If you take dipyridamole, carbamazepine, or methylxanthines (caffeine, theophylline, aminophylline), you need to check with your pharmacist first.

Talk to your doctor or pharmacist before starting this product, especially if you have heart rhythm issues or take heart medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about PEAK ATP 400 mg, straight from the product label.

Brand Swanson
Barcode (UPC) 087614029467
Net contents 30 Veggie Capsule(s)
Market status On market
Date entered into DSLD Mar 22, 2024
DSLD ID 308688
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for PEAK ATP 400 mg by Swanson, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Veggie Capsule(s)
Maximum serving Sizes:
1 Veggie Capsule(s)
Servings per container
30
UPC/BARCODE
087614029467
IngredientAmount% DV
Peak ATP400 mg--

Other ingredients: Hypromellose, Rice Flour, Calcium Laurate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Swanson.com or call 1-800-437-4148

Science-Backed Quality Since 1969

Formulation

Provides optimal cellular energy generation Supports physical energy and healthy circulation

Cellular energy and circulatory health Maximum strength

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take one veggie capsule 30-60 minutes prior to exercise. On non-exercise days, take one capsule in the morning on an empty stomach.

Brand IP Statement(s)

PEAK ATP is a registered trademark of TSI USA, Inc. and is used under license.

Precautions

Warning: For adults only. Keep out of reach of children.

Consult your physician before using this or any product if you are pregnant or nursing, taking medication or have a medical condition.

Do not use if seal is broken.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formula

PEAK ATP 400mg per capsule

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

PEAK ATP 400 mg by Swanson label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

PEAK ATP 400 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in PEAK ATP 400 mg by Swanson

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Veggie Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Peak ATP

Interacts with
47 drugs
400 mg per serving

Adenosine is a natural building block your body uses for energy and cell signaling, and a prescription injectable version is used by doctors to treat...

Peak ATP monograph & interactions

Other (inactive) ingredients: Hypromellose, Rice Flour, Calcium Laurate. These complete the product’s ingredient list but are not active constituents.

Interaction report

PEAK ATP 400 mg by Swanson Drug Interactions

Want to check YOUR meds against PEAK ATP 400 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
47Drugs
2 Major 1 Moderate 44 Minor

Ingredients driving the most interactions

Peak ATP 47

Individual Drug Interactions

The ingredients in PEAK ATP 400 mg interact with 47 drugs. Click any drug to see the details.

1 of the 1 ingredient in PEAK ATP 400 mg interact with drugs. Each result below shows which ingredient is responsible. Peak ATP

Each ingredient & the kinds of drugs it affects

For each ingredient in PEAK ATP 400 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Peak ATP3 drug types · 47 drugs

Dipyridamole (Persantine)

Dipyridamole can increase the therapeutic and toxic effects of adenosine.
Dipyridamole decreases the metabolism of adenosine. Intravenous infusion of adenosine in patients who are taking dipyridamole can cause dizziness, bradycardia, and syncope. Dipyridamole should be discontinued for several days prior to a cardiac stress test using adenosine.

Likelihood Likely Evidence D
Carbamazepine (Tegretol)

Carbamazepine might increase the risk of heart block when used concomitantly with adenosine.
Carbamazepine and adenosine can both cause heart block. Giving them concurrently might produce an additive effect.

Likelihood Possible Evidence D
Methylxanthines

Methylxanthines are competitive antagonists of adenosine and can block its pharmacologic effects.
The methylxanthines, aminophylline, caffeine, and theophylline, can block the effects of adenosine by acting as competitive antagonists at adenosine cell surface receptors. It is recommended that methylxanthines be avoided for 24 hours prior to cardiac stress tests.

Likelihood Possible Evidence D
Peak ATP full monograph & interactions
The maker

Brand information

Manufacturer and brand details for PEAK ATP 400 mg, from the product label.

Swanson

See all Swanson products
Name
Swanson Health Products
City
Fargo
State
ND
ZipCode
58104
Phone Number
1-800-437-4148
Web Address
swanson.com
Pharmacist Counseling Corner

PEAK ATP 400 mg by Swanson: Common Questions

Does PEAK ATP 400 mg by Swanson interact with any medications?
Yes. Based on its ingredients, PEAK ATP 400 mg has a known interaction with 47 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
PEAK ATP 400 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this the same as the prescription adenosine injection doctors use for stress tests?
No. The prescription injectable form is powerful and medically supervised only. This oral capsule is a supplement with limited evidence for safety and effectiveness compared to the injection.
What is adenosine, and why is it in this supplement?
Adenosine is an energy molecule your cells naturally make. It's included here for cardiovascular support, though the oral form's real-world benefits haven't been thoroughly proven.
Can I take this if I drink coffee or take a caffeine pill?
No—caffeine blocks adenosine's effects. Stop caffeine for 24 hours before taking Peak ATP.
Is this safe to take while pregnant or breastfeeding?
The safety data advises against use while breastfeeding. For pregnancy, there isn't enough safety information on file, so talk with your doctor or pharmacist for personalized advice.
What happens if I take this with my heart medications?
That depends on which ones you take. Dipyridamole and carbamazepine are a concern. Use the medication checker below to search your prescriptions, then ask your pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if PEAK ATP 400 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

PEAK ATP 400 mg label
Go deeper

The Full Monographs Behind PEAK ATP 400 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Adenosine

Interacts with 47 drugs

Adenosine is a natural building block your body uses for energy and cell signaling, and a prescription injectable version is used by doctors to treat certain fast heart rhythms. As an over-t...

Read the full Adenosine monograph →
Sources

Sources & How We Checked

PEAK ATP 400 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 10 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Adenosine 10 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Agteresch HJ, Dagnelie PC, van den Berg JW, Wilson JH. Adenosine triphosphate: established and potential clinical applications. Drugs 1999;58:211-32.. PubMed
  3. Agteresch HJ, Dagnelie PC, van der Gaast A, et al. Randomized clinical trial of adenosine 5'-triphosphate in patients with advanced non-small-cell lung cancer. J Natl Cancer Inst 2000;92:321-8.. PubMed
  4. Haskell CM, Wong M, Williams A, Lee LY. Phase I trial of extracellular adenosine 5'-triphosphate in patients with advanced cancer. Med Pediatr Oncol 1996;27:165-73.. DOI
  5. Haskell CM, Mendoza E, Pisters KM, et al. Phase II study of intravenous adenosine 5'-triphosphate in patients with previously untreated stage IIIB and stage IV non-small cell lung cancer. Invest New Drugs 1998;16:81-5.. PubMed
  6. Eisenach JC, Curry R, Hood DD. Dose response of intrathecal adenosine in experimental pain and allodynia. Anesthesiology 2002;97:938-42.. PubMed
  7. Agteresch HJ, Dagnelie PC, Rietveld T, et al. Pharmacokinetics of intravenous ATP in cancer patients. Eur J Clin Pharmacol 2000;56:49-55.. PubMed
  8. Underwood DA. Which medications should be held before a pharmacologic or exercise stress test? Cleve Clin J Med 2002;69:449-50. PubMed
  9. Litmann L, Anderson JD, Monroe MH. Adenosine and Aggrenox: A hazardous combination. Ann Intern Med 2002;137:E-76. PubMed
  10. Faghihi G, Iraji F, Rajaee Harandi M, et al. Comparison of the efficacy of topical minoxidil 5% and adenosine 0.75% solutions on male androgenic alopecia and measuring patient satisfaction rate. Acta Dermatovenerol Croat 2013;21(3):155-9.

See these in context on the Adenosine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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