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Dietary supplement

Pumpkin Seed Oil 1000 mg Ingredients & Drug Interactions

by NutriONN

Pumpkin Seed Oil 1000 mg label
See full label image
Softgel Capsule Category: Fat/fatty Acid
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Pumpkin Seed Oil 1000 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Pumpkin Seed Oil 1000 mg is a dietary supplement by NutriONN with 1 active ingredient. Its ingredients are commonly taken for benign prostatic hyperplasia (bph) symptoms, overactive bladder, eye and skin health (vitamin a source).Based on those ingredients, 1 medication has a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Pumpkin Seed Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Pumpkin Seed Oil 1000 mg by NutriONN

Ask about any prescription or over-the-counter medication and we check it for interactions with Pumpkin Seed Oil 1000 mg by NutriONN — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Pumpkin Seed Oil 1000 mg by NutriONN

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: pumpkin seed oil at 1,000 mg per softgel. The capsule itself is made from gelatin, glycerin, and purified water.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: prostate health and cholesterol support.
  • We looked for evidence on: Benign prostatic hyperplasia (BPH), hypercholesterolemia, dyslipidemia.
  • The strongest evidence on file: Pumpkin is rated "Possibly Effective" for Benign prostatic hyperplasia (BPH) (Natural Medicines).

Pumpkin seed oil is rated possibly effective for benign prostatic hyperplasia (BPH)—an enlarged prostate that causes urinary symptoms in men. For androgenic alopecia (male or female pattern hair loss), interstitial cystitis (bladder pain), intestinal parasite infection, and urinary tract infections, the evidence we hold is insufficient to make a reliable rating either way.

The evidence, ingredient by ingredient Pumpkin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Pumpkin seed oil is generally well tolerated when taken by mouth. The most common side effects in trials are mild abdominal discomfort, diarrhea, nausea, and vomiting.

Very rarely, anaphylaxis (a severe allergic reaction) has been reported. There are also two case reports of adults who developed severe nausea, vomiting, and diarrhea, or substantial hair loss, after consuming meals with bitter-tasting pumpkin or squash—both linked to high levels of cucurbitacin, a compound found mainly in wild pumpkins.

Commercial pumpkin seed oil supplements are generally safe, but safety during pregnancy and breastfeeding hasn't been well studied. Talk with your doctor or pharmacist for personalized advice if you're pregnant, planning to become pregnant, or breastfeeding.

Side effects, ingredient by ingredient Pumpkin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Pumpkin.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: lithium.
  • For scale: 1 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take lithium for mood disorders or bipolar disorder, check with your doctor or pharmacist before adding pumpkin seed oil. The supplement may reduce your body's ability to clear lithium, raising its levels—a Moderate-severity interaction that could require a dose adjustment.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you have an enlarged prostate causing urinary symptoms, pumpkin seed oil may be worth considering—the evidence suggests it could help. If you take lithium, you'll need to check this one with your own doctor or pharmacist first, since it may affect how your body processes it.

For other uses, the evidence isn't strong enough yet to know if it works. Either way, run your full medication list through the checker on this page before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 23, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pumpkin Seed Oil 1000 mg, straight from the product label.

Brand NutriONN
Barcode (UPC) X000W51JW7
Net contents 180 Softgel(s)
Market status On market
Date entered into DSLD Apr 23, 2024
DSLD ID 308906
Product type Fat/fatty Acid
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult Male (18-50 Years), Seniors/Mature (>50 Years) - Men ONLY, Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pumpkin Seed Oil 1000 mg by NutriONN, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
180
UPC/BARCODE
X000W51JW7
IngredientAmount% DV
Pumpkin Seed Oil1000 mg--

Other ingredients: Gelatin, Glycerin, Water, Purified

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Pumpkin Seed Oil is a nutritional oil rich in essential fatty acids (EFAs). Pumpkin seed oil has one of the highest contents of phytosterols which provides support for healthy prostate and can help lower cholesterol. The high fatty acid content helps reduce inflammation in joints and the GI tract.

Nutritional oil 100% natural oil Natural source of essential fatty acids Rich source of phytosterols Pumpkin Seed Oil 1000 mg per softgel

Suggested/Recommended/Usage/Directions

Suggested use: For adults, take one (1) softgel one to four times daily, preferably with meals, or as directed by your health care professional.

Precautions

Caution: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Keep out the reach of children.

Do not use if safety seal is damaged or missing.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or mitigate any disease.

Formulation

Zero Fillers Artificial ingredients

Urinary health Prostate support

Supports prostate health Promotes cardiovascular health

No artificial color, flavor or sweetener, no preservatives, no sugar, no starch, no milk, no lactose, no soy, no gluten, no wheat, no yeast, no fish. Sodium free.

100% natural

Seals/Symbols

Sourced from GMP Certified Facility

Made in USA

FDA Statement of Identity

Dietary Supplement

General Statements

Please recycle For special tips and discounts visit www.nutrionn.com

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Pumpkin Seed Oil 1000 mg by NutriONN label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Pumpkin Seed Oil 1000 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Pumpkin Seed Oil 1000 mg by NutriONN

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container180 Amounts shown are per serving.

Pumpkin Seed Oil

Interacts with
1 drug
1000 mg per serving Form: Cucurbita pepo Seed Oil

Pumpkin is a nutritious squash, and its seeds and seed oil are the parts most often used as supplements, mainly for urinary and prostate symptoms. The...

Pumpkin Seed Oil monograph & interactions

Other (inactive) ingredients: Gelatin, Glycerin, Water, Purified. These complete the product’s ingredient list but are not active constituents.

Interaction report

Pumpkin Seed Oil 1000 mg by NutriONN Drug Interactions

Want to check YOUR meds against Pumpkin Seed Oil 1000 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1Drugs
1 Moderate

Ingredients driving the most interactions

Pumpkin Seed Oil 1

Individual Drug Interactions

The ingredients in Pumpkin Seed Oil 1000 mg interact with 1 drug. Click any drug to see the details.

1 of the 1 ingredient in Pumpkin Seed Oil 1000 mg interact with drugs. Each result below shows which ingredient is responsible. Pumpkin Seed Oil

Each ingredient & the kinds of drugs it affects

For each ingredient in Pumpkin Seed Oil 1000 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Pumpkin Seed Oil1 drug type · 1 drug

Lithium

Pumpkin might reduce excretion and increase levels of lithium.
Pumpkin is thought to have diuretic properties. Theoretically, this might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Pumpkin Seed Oil full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Pumpkin Seed Oil 1000 mg, from the product label.

NutriONN

See all NutriONN products
Name
NutriONN
Street Address
6600 NE 78th Ct. B4, Suite 78399
City
Portland
State
OR
ZipCode
97218
Phone Number
(971) 213-8009
Web Address
www.nutrionn.com
Pharmacist Counseling Corner

Pumpkin Seed Oil 1000 mg by NutriONN: Common Questions

Does Pumpkin Seed Oil 1000 mg by NutriONN interact with any medications?
Yes. Based on its ingredients, Pumpkin Seed Oil 1000 mg has a known interaction with 1 medication. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Pumpkin Seed Oil 1000 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does pumpkin seed oil really help with an enlarged prostate?
The evidence suggests it possibly can help with benign prostatic hyperplasia (BPH), which causes urinary symptoms. That said, more research would help us understand how well it works and for whom.
What are the most common side effects?
Mild abdominal discomfort, diarrhea, nausea, and vomiting are the most common. These are usually manageable. Severe allergic reactions are rare but have been reported.
Is pumpkin seed oil safe during pregnancy or breastfeeding?
Safety hasn't been well studied in pregnancy or while breastfeeding. There isn't enough data to know either way. Talk with your doctor or pharmacist before using it if you're pregnant, planning pregnancy, or nursing.
Can pumpkin seed oil cause hair loss?
There are two case reports of hair loss after consuming bitter-tasting pumpkin or squash, both linked to high cucurbitacin levels found mainly in wild pumpkins. Commercial supplements are unlikely to have this problem, but it's worth knowing about.
Does this product have fillers?
The softgel capsule contains gelatin, glycerin, and purified water as inactive ingredients—these are standard capsule materials.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pumpkin Seed Oil 1000 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pumpkin Seed Oil 1000 mg label
Go deeper

The Full Monographs Behind Pumpkin Seed Oil 1000 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Pumpkin

Interacts with 1 drug

Pumpkin is a nutritious squash, and its seeds and seed oil are the parts most often used as supplements, mainly for urinary and prostate symptoms. The evidence for these uses is limited and...

Read the full Pumpkin monograph →
Sources

Sources & How We Checked

Pumpkin Seed Oil 1000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Pumpkin 5 references
  1. Marks L, Partin AW, Epstein JI, et al. Effects of a saw palmetto herbal blend in men with symptomatic benign prostatic hyperplasia. J Urol 2000;163:1451-6. DOI
  2. Cho YH, Lee SY, Jeong DW, et al. Effect of pumpkin seed oil on hair growth in men with androgenetic alopecia: a randomized, double-blind, placebo-controlled trial. Evid Based Complement Alternat Med 2014;2014:549721. PubMed
  3. Vahlensieck W, Theurer C, Pfitzer E, Patz B, Banik N, Engelmann U. Effects of pumpkin seed in men with lower urinary tract symptoms due to benign prostatic hyperplasia in the one-year, randomized, placebo-controlled GRANU study. Urol Int 2015;94(3):286-95 PubMed
  4. Assouly P. Hair loss associated with cucurbit poisoning. JAMA Dermatol. 2018 May 1;154(5):617-618. PubMed
  5. Gawryjolek J, Ludwig H, Zbikowska-Götz M, Bartuzi Z, Krogulska A. Anaphylaxis after consumption of pumpkin seeds in a 2-y-old child tolerant to its pulp: A case study. Nutrition 2021;89:111272. PubMed

See these in context on the Pumpkin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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