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Dietary supplement

Citrus Bergamot Ingredients & Drug Interactions

by NutriONN

Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Citrus Bergamot is a dietary supplement by NutriONN with 1 active ingredient. Its ingredients are commonly taken for high cholesterol, heart and metabolic health, anxiety and stress (aromatherapy).Based on those ingredients, 410 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Citrus Bergamot extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Citrus Bergamot by NutriONN

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains a single active ingredient: Citrus Bergamot extract. The extract comes from the bergamot orange and carries compounds that research has studied for effects on cholesterol and liver health.

The capsule also contains cellulose as an inactive ingredient (a binder).

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: support heart health and cholesterol levels.
  • We looked for evidence on: Hyperlipidemia, Metabolic syndrome, Impaired glucose tolerance (prediabetes), Nonalcoholic fatty liver disease (NAFLD), triglyceride management, blood vessel health — and 2 related terms.
  • The strongest evidence on file: Bergamot is rated "Possibly Effective" for Hyperlipidemia (Natural Medicines).
  • Also on file: Bergamot is rated "Insufficient Reliable Evidence To Rate" for Nonalcoholic fatty liver disease (NAFLD), Impaired glucose tolerance (prediabetes), Metabolic syndrome.

Bergamot extract is possibly effective for high cholesterol (hyperlipidemia) — the evidence is promising but not yet conclusive. For mental alertness, the data suggests it is possibly ineffective.

We don't have enough reliable evidence to rate it for nonalcoholic fatty liver disease (NAFLD) or autism spectrum disorder, so those claims aren't supported by the data we hold.

The evidence, ingredient by ingredient Bergamot

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

The oral extract appears generally well tolerated when used short-term, though one person in clinical trials reported heartburn. The essential oil is different — it can be toxic if swallowed and cause sun-related skin reactions, so don't confuse the two.

Topical bergamot can cause blisters, redness, photosensitivity, and pigment spots, especially in fair-skinned people. The safety data advises against bergamot during pregnancy and breastfeeding because there isn't enough information to be confident it's safe.

Side effects, ingredient by ingredient Bergamot

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Bergamot.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 410 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications if you take photosensitizing drugs (Moderate severity) or antidiabetes drugs (Moderate severity) — bergamot may increase side effects with both. Use the interaction checker on this page with your exact prescriptions before starting.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Citrus Bergamot by NutriONN may be worth considering if you're interested in cholesterol support and your medications don't conflict with it. If you take any photosensitizing drug or diabetes medication, check with your pharmacist first — and avoid this product entirely if you're pregnant or breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 20, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Citrus Bergamot, straight from the product label.

Brand NutriONN
Barcode (UPC) X001YSBORV
Net contents 90 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Jun 20, 2024
DSLD ID 308890
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Citrus Bergamot by NutriONN, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
90
UPC/BARCODE
X001YSBORV
IngredientAmount% DV
Citrus Bergamot extract500 mg--

Other ingredients: Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Citrus Bergamot is an extract derived from the bergamot orange fruit aka Citrus bergamia. It has been clinically shown to support heart health by promoting healthy cholesterol, blood sugar and triglyceride levels and supporting blood vessel function.

Citrus Bergamot 500mg per capsule

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement take 1 to 2 capsules a day, 30 minutes before a meal, or as directed by your health care professional.

Precautions

Caution: Do not exceed recommended dose.

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Keep out of the reach of children.

Do not use if safety seal is damaged or missing.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or mitigate any disease.

Formulation

Zero added artificial ingredients.

Heart Health Weight Management Antioxidant Promotes healthy cholesterol levels Supports blood glucose metabolism Helps support healthy triglyceride levels

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Sourced from a GMP Certified Facility

100% Quality Guaranteed Made in USA

General Statements

Please Recycle For special tips and discounts visit www.Nutrionn.com

See for yourself

Citrus Bergamot by NutriONN label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Citrus Bergamot by NutriONN

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Citrus Bergamot extract

Interacts with
410 drugs
500 mg per serving Form: Bergamot Polyphenols

Bergamot is a Mediterranean citrus fruit, and its standardized extract is most often used to support cholesterol and heart health, with some early but...

Citrus Bergamot extract monograph & interactions

Other (inactive) ingredients: Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Citrus Bergamot by NutriONN Drug Interactions

Want to check YOUR meds against Citrus Bergamot?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
410Drugs
410 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Citrus Bergamot with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Citrus Bergamot extract2 drug types · 410 drugs

Antidiabetes Drugs

Theoretically, taking bergamot with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research suggests that bergamot juice has hypoglycemic effects.

Likelihood Possible Evidence D
Photosensitizing Drugs

Theoretically, topical bergamot essential oil might increase the risk of side effects when used along with photosensitizing drugs.
Bergamot contains bergapten, which has photosensitizing effects.

Likelihood Probable Evidence D
The maker

Brand information

Manufacturer and brand details for Citrus Bergamot, from the product label.

NutriONN

See all NutriONN products
Name
NutriONN
Street Address
6600 NE 78th Ct. B4, Suite 78399
City
Portland
State
OR
ZipCode
97218
Phone Number
(971) 213-8009
Web Address
www.nutrionn.com
Pharmacist Counseling Corner

Citrus Bergamot by NutriONN: Common Questions

Does Citrus Bergamot by NutriONN interact with any medications?
Yes. Based on its ingredients, Citrus Bergamot has a known interaction with 410 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Citrus Bergamot contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is bergamot extract safe to take long-term?
The extract appears well tolerated short-term, but we don't have long-term safety data on file. If you're thinking of taking it regularly, talk with your pharmacist about what's known and what isn't.
Can I use this if I'm pregnant or breastfeeding?
The safety data advises against it. There isn't enough information to know either way, so it's the safer choice to skip it during pregnancy and while nursing. Talk with your doctor or pharmacist for personalized guidance.
What is bergamot extract used for?
The evidence suggests it's possibly effective for high cholesterol. It's also been studied for liver health and mental alertness, though we don't have reliable data on those uses yet.
Can I use bergamot oil with this product?
No — the essential oil is different from the extract in this capsule and can be toxic if swallowed. This product is the extract form, which is the safer way to take bergamot orally.
What are the side effects?
Taken by mouth, the extract is generally well tolerated, though one person in trials reported heartburn. If you apply bergamot to your skin, it can cause blisters, redness, and sun sensitivity — especially if you have fair skin.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Citrus Bergamot is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Citrus Bergamot label
Sources

Sources & How We Checked

Citrus Bergamot's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 17 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bergamot 17 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Naganuma M, Hirose S, Nakayama Y, et al. A study of the phototoxicity of lemon oil. Arch Dermatol Res 1985;278:31-6. . PubMed
  4. Kaddu, S., Kerl, H., and Wolf, P. Accidental bullous phototoxic reactions to bergamot aromatherapy oil. J.Am.Acad.Dermatol. 2001;45(3):458-461. PubMed
  5. Finsterer, J. Earl Grey tea intoxication. Lancet 4-27-2002;359(9316):1484. PubMed
  6. Gruson, L. M. and Chang, M. W. Berloque dermatitis mimicking child abuse. Arch.Pediatr.Adolesc.Med. 2002;156(11):1091-1093. PubMed
  7. Weisenseel, P. and Woitalla, S. [Toxic mustard plaster dematitis and phototoxic dematitis after application of bergamot oil]. MMW.Fortschr.Med. 12-15-2005;147(51-52):53, 55.
  8. Placzek, M., Fromel, W., Eberlein, B., Gilbertz, K. P., and Przybilla, B. Evaluation of phototoxic properties of fragrances. Acta Derm.Venereol. 2007;87(4):312-316. PubMed
  9. Mollace, V., Sacco, I., Janda, E., Malara, C., Ventrice, D., Colica, C., Visalli, V., Muscoli, S., Ragusa, S., Muscoli, C., Rotiroti, D., and Romeo, F. Hypolipemic and hypoglycaemic activity of bergamot polyphenols: from animal models to human studies. F PubMed
  10. Morliere, P., Huppe, G., Averbeck, D., Young, A. R., Santus, R., and Dubertret, L. In vitro photostability and photosensitizing properties of bergamot oil. Effects of a cinnamate sunscreen. J.Photochem.Photobiol.B 1990;7(2-4):199-208. PubMed
  11. Young, A. R., Walker, S. L., Kinley, J. S., Plastow, S. R., Averbeck, D., Morliere, P., and Dubertret, L. Phototumorigenesis studies of 5-methoxypsoralen in bergamot oil: evaluation and modification of risk of human use in an albino mouse skin model. J.P PubMed
  12. Girard, J., Unkovic, J., Delahayes, J., and Lafille, C. [Phototoxicity of Bergamot oil. Comparison between humans and guinea pigs]. Dermatologica 1979;158(4):229-243.
  13. Zaynoun, S. T., Johnson, B. E., and Frain-Bell, W. A study of oil of bergamot and its importance as a phototoxic agent. II. Factors which affect the phototoxic reaction induced by bergamot oil and psoralen derivatives. Contact Dermatitis 1977;3(5):225-23 PubMed
  14. Zacher, K. D. and Ippen, H. [Contact dermatitis caused by bergamot oil]. Derm.Beruf.Umwelt. 1984;32(3):95-97.
  15. Yasui, Y. and Hirone, T. Action spectrum for bergamot-oil phototoxicity measured by sunburn cell counting. J.Dermatol. 1994;21(5):319-322. PubMed
  16. Zaynoun, S. T., Johnson, B. E., and Frain-Bell, W. A study of oil of bergamot and its importance as a phototoxic agent. I. Characterization and quantification of the photoactive component. Br.J.Dermatol. 1977;96(5):475-482. PubMed
  17. Bruno A, Pandolfo G, Crucitti M, Cedro C, Zoccali RA, Muscatello MRA. Bergamot Polyphenolic Fraction Supplementation Improves Cognitive Functioning in Schizophrenia: Data From an 8-Week, Open-Label Pilot Study. J Clin Psychopharmacol 2017;37(4):468-71. PubMed

See these in context on the Bergamot monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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