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Dietary supplement

Organic Bergamot Ingredients & Drug Interactions

by Zongle Therapeutics

Organic Bergamot label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Organic Bergamot against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Organic Bergamot is a dietary supplement by Zongle Therapeutics with 1 active ingredient. Its ingredients are commonly taken for high cholesterol, heart and metabolic health, anxiety and stress (aromatherapy).Based on those ingredients, 410 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bergamot. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Organic Bergamot by Zongle Therapeutics

Ask about any prescription or over-the-counter medication and we check it for interactions with Organic Bergamot by Zongle Therapeutics — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Organic Bergamot by Zongle Therapeutics

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 27, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: bergamot, delivered as a liquid. Bergamot is a citrus fruit, and this formula is cold-pressed from the oil — a concentration method that preserves the plant's natural compounds.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: calming, stress relief, and metabolic support.
  • We looked for evidence on: Stress, Pre-procedural anxiety, Metabolic syndrome, Hyperlipidemia, anxiety, skin health — and 1 related terms.
  • The strongest evidence on file: Bergamot is rated "Possibly Effective" for Hyperlipidemia (Natural Medicines).
  • Also on file: Bergamot is rated "Insufficient Reliable Evidence To Rate" for Pre-procedural anxiety, Stress, Metabolic syndrome.

Bergamot is possibly effective for high cholesterol (hyperlipidemia) according to available evidence. For mental alertness, the data suggests it's possibly ineffective.

For nonalcoholic fatty liver disease and autism spectrum disorder, there isn't enough reliable evidence yet to say how well it works.

The evidence, ingredient by ingredient Bergamot

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Bergamot oral extract appears generally well tolerated when used short-term. However, the essential oil can be toxic if swallowed, so don't take it internally unless it's specifically formulated for oral use.

Topically, bergamot carries safety concerns — it can cause blisters, redness, skin lesions, and sun sensitivity, especially in fair-skinned people, because of its photosensitizing compounds. The safety data advises against bergamot supplements and oil during pregnancy, and breastfeeding safety is unknown, so avoiding it while breastfeeding is the safer choice.

Side effects, ingredient by ingredient Bergamot

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Bergamot.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 410 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before taking this product if you use photosensitizing drugs (which make your skin more sun-sensitive) or diabetes medications. Both carry moderate interaction risks with bergamot.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Bergamot may help with high cholesterol based on available evidence, but it's not right for everyone. If you take diabetes medications or drugs that increase sun sensitivity, or if you're pregnant or breastfeeding, talk with your doctor or pharmacist before starting.

Also check your exact medications on this page's interaction tool before you begin.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 22, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Organic Bergamot, straight from the product label.

Brand Zongle Therapeutics
Barcode (UPC) 856426006344
Net contents 1 Fluid Ounce(s); 30 mL
Market status On market
Date entered into DSLD Sep 22, 2022
DSLD ID 276614
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Organic, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Organic Bergamot by Zongle Therapeutics, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Drop(s)
Maximum serving Sizes:
1 Drop(s)
Servings per container
500
UPC/BARCODE
856426006344
IngredientAmount% DV
Bergamot60 mg--

Other ingredients: Bergamot Oil, Cold-Pressed

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

For aromatic, topical or internal use.

For internal use dilute one drop in 4 fl. oz. of liquid. Dilute for kids or sensitive skin.

Formulation

USDA Certified Organic

Joyful, fresh, calming and soothing Cleanses and purifies skin Helps in relieving stress Maintains healthy metabolic function Very popular massage oil

Therapeutic Grade

Origin: Italy Bottled in USA

Certified Organic by GCIAOCP

GMO free Artificial Ingredients free Paraben free Pesticide free Preservatives free Gluten free

Vegan

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Caution: Possible skin sensitivity.

Keep out of reach of children.

If you are pregnant, nursing, or under a doctor's care, consult your physician.

Avoid contact with eyes, inner ears, and sensitive areas. Avoid sunlight or UV rays for up to 12 hours after applying product.

Formula

Citrus bergamia

FDA Statement of Identity

Essential Oil Supplement

Seals/Symbols

USDA Organic

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Organic Bergamot by Zongle Therapeutics label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Organic Bergamot label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Organic Bergamot by Zongle Therapeutics

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Drop(s) Dosage formLiquid Servings per container500 Amounts shown are per serving.

Bergamot

Interacts with
410 drugs
60 mg per serving

Bergamot is a Mediterranean citrus fruit, and its standardized extract is most often used to support cholesterol and heart health, with some early but...

Bergamot monograph & interactions

Other (inactive) ingredients: Bergamot Oil, Cold-Pressed. These complete the product’s ingredient list but are not active constituents.

Interaction report

Organic Bergamot by Zongle Therapeutics Drug Interactions

Want to check YOUR meds against Organic Bergamot?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
410Drugs
410 Moderate

Ingredients driving the most interactions

Bergamot 410

Individual Drug Interactions

The ingredients in Organic Bergamot interact with 410 drugs. Click any drug to see the details.

1 of the 1 ingredient in Organic Bergamot interact with drugs. Each result below shows which ingredient is responsible. Bergamot

Each ingredient & the kinds of drugs it affects

For each ingredient in Organic Bergamot with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Bergamot2 drug types · 410 drugs

Antidiabetes Drugs

Theoretically, taking bergamot with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research suggests that bergamot juice has hypoglycemic effects.

Likelihood Possible Evidence D
Photosensitizing Drugs

Theoretically, topical bergamot essential oil might increase the risk of side effects when used along with photosensitizing drugs.
Bergamot contains bergapten, which has photosensitizing effects.

Likelihood Probable Evidence D
Bergamot full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Organic Bergamot, from the product label.

Zongle Therapeutics

See all Zongle Therapeutics products
Name
Zongle Therapeutics LLC
City
Norcross
State
GA
ZipCode
30093
Web Address
www.zongletherapeutics.com
Pharmacist Counseling Corner

Organic Bergamot by Zongle Therapeutics: Common Questions

Does Organic Bergamot by Zongle Therapeutics interact with any medications?
Yes. Based on its ingredients, Organic Bergamot has a known interaction with 410 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Organic Bergamot contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I use Zongle Organic Bergamot if I take diabetes medication?
Not without checking first with your doctor or pharmacist. Bergamot may lower blood sugar, so taking it with antidiabetes drugs could increase your risk of low blood sugar (hypoglycemia). Your healthcare provider can tell you whether it's safe for your specific situation.
Is the essential oil safe to swallow?
No. Bergamot essential oil can be toxic if taken internally. Only use this product as directed on the label — if it's formulated for oral use, follow those instructions; if it's for topical or aromatherapy use, stick to that.
What does bergapten do, and why should I care?
Bergapten is a compound in bergamot that makes your skin more sensitive to sunlight (photosensitizing). This is why bergamot can cause sun-related skin reactions like blisters and redness, especially if you're fair-skinned or taking medications that also increase sun sensitivity.
Can I use this product while pregnant or breastfeeding?
The safety data advises against bergamot supplements during pregnancy. Breastfeeding safety is unknown, so avoiding it while breastfeeding is the safer choice. Talk with your doctor or pharmacist if you're pregnant or nursing and interested in bergamot.
What side effects might I see from taking bergamot orally?
Orally, bergamot extract seems well tolerated short-term. One clinical case linked it to heartburn. Topically, though, it's riskier — it can cause blisters, redness, skin lesions, pustules, pigment spots, and sun sensitivity.
Does bergamot really help with cholesterol?
According to available evidence, it's possibly effective for high cholesterol. That means there's some promising research, but it's not definite. Talk with your doctor about whether it fits into your overall plan.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Organic Bergamot is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Organic Bergamot label
Go deeper

The Full Monographs Behind Organic Bergamot’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Bergamot

Interacts with 410 drugs

Bergamot is a Mediterranean citrus fruit, and its standardized extract is most often used to support cholesterol and heart health, with some early but promising research. The essential oil i...

Read the full Bergamot monograph →
Sources

Sources & How We Checked

Organic Bergamot's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 17 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bergamot 17 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Naganuma M, Hirose S, Nakayama Y, et al. A study of the phototoxicity of lemon oil. Arch Dermatol Res 1985;278:31-6. . PubMed
  4. Kaddu, S., Kerl, H., and Wolf, P. Accidental bullous phototoxic reactions to bergamot aromatherapy oil. J.Am.Acad.Dermatol. 2001;45(3):458-461. PubMed
  5. Finsterer, J. Earl Grey tea intoxication. Lancet 4-27-2002;359(9316):1484. PubMed
  6. Gruson, L. M. and Chang, M. W. Berloque dermatitis mimicking child abuse. Arch.Pediatr.Adolesc.Med. 2002;156(11):1091-1093. PubMed
  7. Weisenseel, P. and Woitalla, S. [Toxic mustard plaster dematitis and phototoxic dematitis after application of bergamot oil]. MMW.Fortschr.Med. 12-15-2005;147(51-52):53, 55.
  8. Placzek, M., Fromel, W., Eberlein, B., Gilbertz, K. P., and Przybilla, B. Evaluation of phototoxic properties of fragrances. Acta Derm.Venereol. 2007;87(4):312-316. PubMed
  9. Mollace, V., Sacco, I., Janda, E., Malara, C., Ventrice, D., Colica, C., Visalli, V., Muscoli, S., Ragusa, S., Muscoli, C., Rotiroti, D., and Romeo, F. Hypolipemic and hypoglycaemic activity of bergamot polyphenols: from animal models to human studies. F PubMed
  10. Morliere, P., Huppe, G., Averbeck, D., Young, A. R., Santus, R., and Dubertret, L. In vitro photostability and photosensitizing properties of bergamot oil. Effects of a cinnamate sunscreen. J.Photochem.Photobiol.B 1990;7(2-4):199-208. PubMed
  11. Young, A. R., Walker, S. L., Kinley, J. S., Plastow, S. R., Averbeck, D., Morliere, P., and Dubertret, L. Phototumorigenesis studies of 5-methoxypsoralen in bergamot oil: evaluation and modification of risk of human use in an albino mouse skin model. J.P PubMed
  12. Girard, J., Unkovic, J., Delahayes, J., and Lafille, C. [Phototoxicity of Bergamot oil. Comparison between humans and guinea pigs]. Dermatologica 1979;158(4):229-243.
  13. Zaynoun, S. T., Johnson, B. E., and Frain-Bell, W. A study of oil of bergamot and its importance as a phototoxic agent. II. Factors which affect the phototoxic reaction induced by bergamot oil and psoralen derivatives. Contact Dermatitis 1977;3(5):225-23 PubMed
  14. Zacher, K. D. and Ippen, H. [Contact dermatitis caused by bergamot oil]. Derm.Beruf.Umwelt. 1984;32(3):95-97.
  15. Yasui, Y. and Hirone, T. Action spectrum for bergamot-oil phototoxicity measured by sunburn cell counting. J.Dermatol. 1994;21(5):319-322. PubMed
  16. Zaynoun, S. T., Johnson, B. E., and Frain-Bell, W. A study of oil of bergamot and its importance as a phototoxic agent. I. Characterization and quantification of the photoactive component. Br.J.Dermatol. 1977;96(5):475-482. PubMed
  17. Bruno A, Pandolfo G, Crucitti M, Cedro C, Zoccali RA, Muscatello MRA. Bergamot Polyphenolic Fraction Supplementation Improves Cognitive Functioning in Schizophrenia: Data From an 8-Week, Open-Label Pilot Study. J Clin Psychopharmacol 2017;37(4):468-71. PubMed

See these in context on the Bergamot monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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