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Dietary supplement

Organic Marjoram Ingredients & Drug Interactions

by Zongle Therapeutics

Organic Marjoram label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Organic Marjoram against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Organic Marjoram is a dietary supplement by Zongle Therapeutics with 1 active ingredient. Its ingredients are commonly taken for digestive upset, sleep and relaxation, respiratory complaints (cough, congestion).Based on those ingredients, 338 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Marjoram. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Organic Marjoram by Zongle Therapeutics

Ask about any prescription or over-the-counter medication and we check it for interactions with Organic Marjoram by Zongle Therapeutics — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Organic Marjoram by Zongle Therapeutics

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: marjoram, supplied as an organic essential oil extract. The product is a liquid form, which typically means the marjoram oil is dissolved or suspended in a base.

Inactive ingredients (the base and any other excipients) are also listed as organic marjoram oil.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Marjoram's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: cardiovascular, immune, hormonal, and digestive health.
  • We looked for evidence on: Dysmenorrhea, Polycystic ovary syndrome (PCOS), Immune function, Digestive health, Hormonal balance.
  • The closest evidence on file: Marjoram is rated "Insufficient Reliable Evidence To Rate" for Polycystic ovary syndrome (PCOS) (Natural Medicines).
  • Also on file: Marjoram is rated "Insufficient Reliable Evidence To Rate" for Dysmenorrhea.

The evidence for marjoram's effectiveness at treating specific conditions isn't established in our data. The product may be marketed for asthma, Parkinson disease, PCOS, or menstrual cramps (dysmenorrhea), but we hold insufficient reliable evidence to rate whether it works for any of these.

If you're considering it for a particular health concern, talk to your pharmacist or doctor about what the science actually supports.

The evidence, ingredient by ingredient Marjoram

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Marjoram is generally well tolerated when used as a food or seasoning. However, concentrated extracts and essential oils — which is what you have here — have limited human safety data.

A small number of people have reported skin reactions: a clinical trial noted possible allergic skin inflammation in children with pre-existing eczema after extended use of essential oils including sweet marjoram, and one case report described a woman whose perioral skin inflammation worsened after eating marjoram-seasoned food. In pregnancy, the safety data advises against medicinal or concentrated amounts of marjoram due to lack of safety data.

Food amounts are likely fine, but this product is a concentrated extract, so pregnant people should avoid it. Lactation safety data isn't on file for marjoram.

Side effects, ingredient by ingredient Marjoram

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Marjoram.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 338 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check your medications if you take blood thinners or antiplatelet drugs (like aspirin, warfarin, or clopidogrel), anticholinergic drugs (like benztropine or medications for overactive bladder), or cholinergic drugs (like donepezil). All three drug classes are documented to interact with marjoram in medicinal amounts.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product is best suited for someone who wants marjoram's traditional uses and doesn't take blood thinners or medications for Parkinson's, Alzheimer's, or bladder control. If you take any of those drug classes — or any prescription at all — check it with your pharmacist before starting.

Pregnant people should avoid medicinal doses.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Organic Marjoram, straight from the product label.

Brand Zongle Therapeutics
Barcode (UPC) 856426006481
Net contents 1 Fluid Ounce(s); 30 mL
Market status On market
Date entered into DSLD Oct 24, 2022
DSLD ID 276637
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Organic, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Organic Marjoram by Zongle Therapeutics, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Drop(s)
Maximum serving Sizes:
1 Drop(s)
Servings per container
500
UPC/BARCODE
856426006481
IngredientAmount% DV
Marjoram60 mg--

Other ingredients: organic Origanum majorana (Marjoram) oil

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

For aromatic, topical or internal use.

For internal use dilute one drop in 4 fl. oz. of liquid.

Formulation

USDA Certified Organic

May support a healthy cardiovascular function Promotes healthy immune system Supports healthy hormonal balance Helps with healthy digestion

Certified Organic

Therapeutic grade

GMO free Artificial ingredients free Paraben free Pesticide free Preservatives free Gluten free

Vegan

Origin: Spain Bottled in USA

Certified Organic by GCIAOCP

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Caution: Possible skin sensitivity.

Keep out of reach of children.

If you are pregnant, nursing, or under a doctor's care, consult your physician.

Avoid contact with eyes, inner ears, and sensitive areas.

Formula

Origanum majorana

FDA Statement of Identity

Essential Oil Supplement

Seals/Symbols

USDA Organic

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Organic Marjoram by Zongle Therapeutics label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Organic Marjoram label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Organic Marjoram by Zongle Therapeutics

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Drop(s) Dosage formLiquid Servings per container500 Amounts shown are per serving.

Marjoram

Interacts with
338 drugs
60 mg per serving

Marjoram is a Mediterranean kitchen herb related to oregano that is widely used in food and traditional medicine for digestive, sleep, and respiratory...

Marjoram monograph & interactions

Other (inactive) ingredients: Organic Origanum majorana (Marjoram) oil. These complete the product’s ingredient list but are not active constituents.

Interaction report

Organic Marjoram by Zongle Therapeutics Drug Interactions

Want to check YOUR meds against Organic Marjoram?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
338Drugs
338 Moderate

Ingredients driving the most interactions

Marjoram 338

Individual Drug Interactions

The ingredients in Organic Marjoram interact with 338 drugs. Click any drug to see the details.

1 of the 1 ingredient in Organic Marjoram interact with drugs. Each result below shows which ingredient is responsible. Marjoram

Each ingredient & the kinds of drugs it affects

For each ingredient in Organic Marjoram with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Marjoram3 drug types · 338 drugs

Anticholinergic Drugs

In vitro research suggests that marjoram extract can inhibit acetylcholinesterase activity. Theoretically, using marjoram in medicinal amounts along with anticholinergic drugs might decrease the effectiveness of marjoram or the anticholinergic agent.
Some anticholinergic drugs include atropine, benztropine (Cogentin), biperiden (Akineton), procyclidine (Kemadrin), and trihexyphenidyl (Artane).

Likelihood Possible Evidence D
Anticoagulant/Antiplatelet Drugs

In vitro research suggests that marjoram extract inhibits platelet aggregation and adhesion. Theoretically, marjoram might increase the risk of bleeding when used in medicinal amounts along with antiplatelet or anticoagulant drugs.
Some anticoagulant or antiplatelet drugs include aspirin, clopidogrel (Plavix), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, ticlopidine (Ticlid), warfarin (Coumadin), and others.

Likelihood Possible Evidence D
Cholinergic Drugs

In vitro research suggests that marjoram extract can inhibit acetylcholinesterase activity. Theoretically, using marjoram in medicinal amounts along with cholinergic drugs might have additive effects and increase the risk of cholinergic side effects.
Cholinergic drugs include bethanechol (Urecholine), donepezil (Aricept), echothiophate (Phospholine Iodide), edrophonium (Enlon, Reversol, Tensilon), neostigmine (Prostigmin), physostigmine (Antilirium), pyridostigmine (Mestinon, Regonol), succinylcholine (Anectine, Quelicin), and tacrine (Cognex).

Likelihood Possible Evidence D
Marjoram full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Organic Marjoram, from the product label.

Zongle Therapeutics

See all Zongle Therapeutics products
Name
Zongle Therapeutics LLC
City
Norcross
State
GA
ZipCode
30093
Web Address
www.zongletherapeutics.com
Pharmacist Counseling Corner

Organic Marjoram by Zongle Therapeutics: Common Questions

Does Organic Marjoram by Zongle Therapeutics interact with any medications?
Yes. Based on its ingredients, Organic Marjoram has a known interaction with 338 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Organic Marjoram contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is marjoram safe to use while pregnant?
The safety data advises against medicinal or concentrated amounts of marjoram in pregnancy because we don't have enough human safety data. This product is a concentrated extract, so pregnant people should avoid it. Food amounts of marjoram are likely fine, but talk with your doctor or pharmacist for personalized advice.
Can I use this if I take aspirin or another blood thinner?
Not without checking with your pharmacist first. Lab research suggests marjoram can slow blood clotting, and combining it with blood thinners or antiplatelet drugs in medicinal amounts might increase your bleeding risk. Use the medication checker on this page or call your pharmacist to verify your specific drug.
What does this product actually treat?
We don't have reliable evidence that marjoram works for asthma, Parkinson disease, PCOS, or menstrual cramps. The evidence isn't established in our data, so talk to your doctor about whether it's right for your situation.
Can I get allergic reactions from this?
Yes, though allergic reactions are uncommon. A clinical trial noted possible skin inflammation in children with pre-existing eczema after extended use of essential oils including sweet marjoram. One woman also developed skin inflammation after eating marjoram-seasoned food. If you develop a rash or skin irritation, stop using it and talk to your doctor.
Is this product a liquid or concentrated oil?
It's a liquid extract form of marjoram essential oil. Because it's concentrated rather than a food-amount seasoning, it has more limited human safety data and carries higher interaction risk with medications.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Organic Marjoram is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Organic Marjoram label
Go deeper

The Full Monographs Behind Organic Marjoram’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Marjoram

Interacts with 338 drugs

Marjoram is a Mediterranean kitchen herb related to oregano that is widely used in food and traditional medicine for digestive, sleep, and respiratory complaints. Most of its health claims r...

Read the full Marjoram monograph →
Sources

Sources & How We Checked

Organic Marjoram's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Marjoram 11 references
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Orhan, I., Kartal, M., Kan, Y., and Sener, B. Activity of essential oils and individual components against acetyl- and butyrylcholinesterase. Z.Naturforsch.C. 2008;63(7-8):547-553.
  3. Farkas, J. Perioral dermatitis from marjoram, bay leaf and cinnamon. Contact Dermatitis 1981;7(2):121. PubMed
  4. Anderson C, Lis-Balchin M, Kirk-Smith M. Evaluation of massage with essential oils on childhood atopic eczema. Phytother Res 2000;14(6):452-6. PubMed
  5. Ou, M. C., Hsu, T. F., Lai, A. C., Lin, Y. T., and Lin, C. C. Pain relief assessment by aromatic essential oil massage on outpatients with primary dysmenorrhea: a randomized, double-blind clinical trial. J Obstet.Gynaecol.Res 2012;38(5):817-822. PubMed
  6. Chung, Y. K., Heo, H. J., Kim, E. K., Kim, H. K., Huh, T. L., Lim, Y., Kim, S. K., and Shin, D. H. Inhibitory effect of ursolic acid purified from Origanum majorana L on the acetylcholinesterase. Mol.Cells 4-30-2001;11(2):137-143. DOI
  7. Yazdanparast, R. and Shahriyary, L. Comparative effects of Artemisia dracunculus, Satureja hortensis and Origanum majorana on inhibition of blood platelet adhesion, aggregation and secretion. Vascul.Pharmacol 2008;48(1):32-37. PubMed
  8. Mohamed MS, Saad HH, and Abd El Khalek MG. Daily consumption of marjoram oil improve the health status of patients with asthma. Pakistan Journal of Nutrition. 2008;7(2):312-316. DOI
  9. Bina F, Rahimi R. Sweet marjoram: a review of ethnopharmacology, phytochemistry, and biological activities. J Evid Based Complementary Altern Med 2017;22(1):175-85.
  10. Haj-Husein I, Tukan S, Alkazaleh F. The effect of marjoram (Origanum majorana) tea on the hormonal profile of women with polycystic ovary syndrome: a randomized controlled pilot study. J Hum Nutr Diet 2016;29(1):105-11.
  11. Chahra C, Anis H, Bissene D, et al. The effect of Origanum majorana tea on motor and non-motor symptoms in patients with idiopathic Parkinson's disease: A randomized controlled pilot study. Parkinsonism Relat Disord. 2021 Oct;91:23-7. PubMed

See these in context on the Marjoram monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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