Phosphatidylcholine (Sunflower) Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Phosphatidylcholine (Sunflower) against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Phosphatidylcholine (Sunflower) is a dietary supplement by Pure Encapsulations with 1 active ingredient. Its ingredients are commonly taken for liver health, memory and brain support, ulcerative colitis.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Phosphatidylcholine (Sunflower) by Pure Encapsulations
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: phosphatidylcholine derived from sunflower. Phosphatidylcholine is a naturally occurring compound found in cell membranes and is involved in cell structure and function throughout your body.
The capsule itself is gelatin, and the product also contains sunflower lecithin and medium-chain triglycerides as inactive ingredients to support absorption and stability.
Does it work?
Moderate evidence
The evidence for phosphatidylcholine is mixed. For ulcerative colitis (a type of inflammatory bowel disease), there's possibly effective evidence—meaning some research suggests it may help, but more study is needed to be sure.
For nonalcoholic fatty liver disease, alcohol-related liver disease, Alzheimer disease, and anxiety, the evidence is insufficient—we simply don't have enough reliable data to rate whether it works for these conditions.
How safe is it?
Well-documented data
Phosphatidylcholine is generally well tolerated when taken by mouth. At typical supplement doses, the most common side effects are mild: altered taste, bloating, diarrhea, nausea, and sweating.
High doses—especially 30 grams per day or more—are more likely to cause digestive upset and diarrhea. Choline (which your body gets from phosphatidylcholine) is needed in pregnancy, but the safety of taking phosphatidylcholine supplements beyond food sources during pregnancy isn't well studied.
Similarly, there isn't enough reliable data on supplement use while breastfeeding. Talk with your doctor or pharmacist before taking this product if you're pregnant, planning to become pregnant, or breastfeeding.
Meds to double-check
No known interactions
No interactions are documented in our data for phosphatidylcholine with any medication types. Always use the interaction checker on this page to search your exact medications before starting.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
Phosphatidylcholine may be worth considering if you're interested in supporting cell health or have ulcerative colitis, though evidence for that condition is still emerging. Because the data on interactions is absent, check your own medications with the tool on this page before you start.
If you're pregnant, breastfeeding, or have liver disease or neurological concerns, speak with your doctor or pharmacist first to see if this product makes sense for you.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Phosphatidylcholine (Sunflower), straight from the product label.
| Brand | Pure Encapsulations |
|---|---|
| Barcode (UPC) | 766298018669 |
| Net contents | 90 Softgel Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Mar 25, 2021 |
| DSLD ID | 246170 |
| Product type | Fat/fatty Acid |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Phosphatidylcholine (Sunflower) by Pure Encapsulations, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 15 Calorie(s) | -- |
| Total Fat | 1.5 Gram(s) | 2% |
| Total Phosphatidylcholine | 550 mg | -- |
Other ingredients: Gelatin Capsule, Sunflower Lecithin, Medium-Chain Triglycerides
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Storage
Store in a cool, dry place.
Suggested/Recommended/Usage/Directions
Recommendations: As a dietary supplement, take 2 capsules daily, with a meal.
Precautions
Warning:If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.
Keep out of the reach of children.
Use only if safety seal is intact.
General Statements
Scan to learn about our hypoallergenic supplements
Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity.
Formula
Phospholipid-bound choline to support cellular function, cognitive function and live health
Formulation
Gluten-free, non-GMO & hypoallergenic
Gluten-free, non-GMO & hypoallergenic
FDA Statement of Identity
Dietary Supplement
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Phosphatidylcholine (Sunflower) by Pure Encapsulations label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Phosphatidylcholine (Sunflower) by Pure Encapsulations
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size2 Softgel Capsule(s) Dosage formCapsule Servings per container45 Amounts shown are per serving.
Total Phosphatidylcholine
No knowninteractions
Phosphatidylcholine is a phospholipid that is part of every cell membrane and a source of choline. People take it for liver, brain, and gut health, bu...
Total Phosphatidylcholine monograph & interactionsOther (inactive) ingredients: Gelatin Capsule, Sunflower Lecithin, Medium-Chain Triglycerides. These complete the product’s ingredient list but are not active constituents.
Phosphatidylcholine (Sunflower) by Pure Encapsulations Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Phosphatidylcholine (Sunflower). This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Phosphatidylcholine (Sunflower), from the product label.
Pure Encapsulations
See all Pure Encapsulations products- Name
- Pure Encapsulations
- Street Address
- 490 Boston Post Road
- City
- Sudbury
- State
- MA
- Phone Number
- 1-800-753-2277
- Web Address
- www.PureEncapsulations.com
Phosphatidylcholine (Sunflower) by Pure Encapsulations: Common Questions
Does Phosphatidylcholine (Sunflower) by Pure Encapsulations interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What does phosphatidylcholine actually do?
Can I take this if I'm pregnant or breastfeeding?
What side effects should I expect?
Is this going to help my liver or brain health?
Does this product have fillers or other stuff I don't need?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Phosphatidylcholine (Sunflower) is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Phosphatidylcholine (Sunflower)’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Phosphatidylcholine (Sunflower)'s label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 15 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Phosphatidylcholine 15 references
- Domino EF, May WW, Demetriou S, et al. Lack of clinically significant improvement of patients with tardive dyskinesia following phosphatidylcholine therapy. Biol Psychiatry 1985;20:1189-96. PubMed
- Aronson PJ, Lorincz AL. Promotion of palmar sweating with oral phosphatidylcholine. Acta Derm Venereol 1985;65:19-24. DOI
- Hexsel DM, Serra M, de Oliveira Dal'Forno T, et al. Cosmetic uses of injectable phosphatidylcholine on the face. Otolaryngol Clin North Am 2005;38:1119-29. PubMed
- Kopera D, Binder B, Toplak H, et al. Histopathologic changes after intralesional application of phosphatidylcholine for lipoma reduction: report of a case. Am J Dermatopathol 2006;28:331-3. PubMed
- Rittes PG. The use of phosphatidylcholine for correction of lower lid bulging due to prominent fat pads. Dermatol Surg 2001;27:391-2. PubMed
- Rotunda AM, Kolodney MS. Mesotherapy and phosphatidylcholine injections: historical clarification and review. Dermatol Surg 2006;32:465-80. PubMed
- Hexsel D, Serra M, Mazzuco R, et al. Phosphatidylcholine in the treatment of localized fat. J Drugs Dermatol 2003;2:511-8.
- Hasengschwandtner F. Phosphatidylcholine treatment to induce lipolysis. Cosmet Dermatol 2005;4:308-13. PubMed
- Rittes PG. The use of phosphatidylcholine for correction of localized fat deposits. Aesthetic Plast Surg 2003;27:315-8. PubMed
- Ablon G, Rotunda AM. Treatment of lower eyelid fat pads using phosphatidylcholine: clinical trial and review. Dermatol Surg 2004;30:422-7. PubMed
- Loguercio C, Andreone P, Brisc C, et al. Silybin combined with phosphatidylcholine and vitamin E in patients with nonalcoholic fatty liver disease: a randomized controlled trial. Free Radic Biol Med 2012;52(9):1658-65. PubMed
- Panos, J. M., Palson, R., Johnson, R., Portmann, B., and Williams, R. Polyunsaturated phosphatidylcholine for acute alcoholic hepatitis: a double blind randomized placebo controlled trial. Eur.J.Gastroenterol 1990;2:351-355.
- Stremmel W, Braun A, Hanemann A, Ehehalt R, Autschbach F, Karner M. Delayed release phosphatidylcholine in chronic-active ulcerative colitis: a randomized, double-blinded, dose finding study. J Clin Gastroenterol 2010;44(5):e101-7. PubMed
- Stremmel W, Ehehalt R, Autschbach F, Karner M. Phosphatidylcholine for steroid-refractory chronic ulcerative colitis: a randomized trial. Ann Intern Med. 2007;147(9):603-10. PubMed
- Stremmel W, Vural H, Evliyaoglu O, Weiskirchen R. Delayed Release Phosphatidylcholine is Effective for Treatment of Ulcerative Colitis: A Meta-Analysis. Dig Dis 2021;39(5):508-515. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC