No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Pygeum Africanum Extract Ingredients & Drug Interactions

by BulkSupplements.com

Powder Category: Botanical
No known interaction
The interaction bottom line No known interaction

Pygeum Africanum Extract is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for benign prostatic hyperplasia (bph) symptoms, urinary symptoms in men, prostate health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Pygeum Africanum Extract by BulkSupplements.com

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Pygeum africanum Bark Extract, a traditional herbal ingredient used to support prostate health. It comes as a powder with no inactive ingredients listed.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: prostate health.
  • We looked for evidence on: Benign prostatic hyperplasia (BPH), urinary symptoms, prostate function.
  • The strongest evidence on file: Pygeum is rated "Likely Effective" for Benign prostatic hyperplasia (BPH) (Natural Medicines).

Pygeum is likely effective for benign prostatic hyperplasia (BPH) — that's the non-cancerous enlargement of the prostate that causes urinary symptoms in men. For Alzheimer's disease, sexual desire, psychosis, and malaria, the evidence isn't established in the data we hold.

The safety data are limited, especially for long-term use, so talk with your doctor about whether it's right for your situation.

The evidence, ingredient by ingredient Pygeum

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Pygeum is generally well tolerated short-term, though quality and long-term safety data are limited. In clinical trials, some people reported nausea and abdominal pain, but these occurred at rates similar to placebo.

Pygeum is not recommended in pregnancy — there's no established safe use for pregnant people. There isn't enough safety information to recommend it while breastfeeding, so it's best avoided during that time.

Side effects, ingredient by ingredient Pygeum

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the active ingredient we checked. Run your specific medications through the search tool on this page to confirm, and ask your doctor or pharmacist before you start.

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Pygeum may help if you're a man dealing with prostate enlargement symptoms, but the long-term safety picture isn't fully clear. Pregnancy and breastfeeding are off-limits due to limited safety data.

Talk with your doctor or pharmacist before starting to make sure it fits your situation and doesn't clash with anything else you're taking.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 23, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Pygeum Africanum Extract, straight from the product label.

Brand BulkSupplements.com
Barcode (UPC) X001R0FJYZ
Net contents 100 Gram(s); 3.5 Ounce(s)
Market status On market
Date entered into DSLD Apr 23, 2024
DSLD ID 311747
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult Male (18-50 Years), Seniors/Mature (>50 Years) - Men ONLY, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Pygeum Africanum Extract by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
500 Milligram(s)
Maximum serving Sizes:
500 Milligram(s)
Servings per container
200
UPC/BARCODE
X001R0FJYZ
IngredientAmount% DV
Pygeum africanum Bark Extract500 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Bulksupplements.com Clean & pure bulk supplements

Formulation

Color may vary

Free of: Added sugar, soy, dairy, yeast, gluten

FDA Disclaimer Statement

Warning: This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Always consult a physician before taking any dietary supplement.

Keep out of reach of children.

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take 500 mg (about 1/5 tsp) once daily with meals, or as directed by a physician.

Storage

Store in a dry, cool place

Formula

Pygeum bark

Prostate supplements for men

General Statements

Use an accurate milligram scale. Contents are sold by weight, not volume. Settling may occur. New

See for yourself

Pygeum Africanum Extract by BulkSupplements.com label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Pygeum Africanum Extract by BulkSupplements.com

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size500 Milligram(s) Dosage formPowder Servings per container200 Amounts shown are per serving.

Pygeum africanum Bark Extract

No known
interactions
500 mg per serving

Pygeum is an extract from the bark of the African cherry tree that is most often used to ease urinary symptoms linked to an enlarged prostate. Some st...

Pygeum africanum Bark Extract monograph & interactions
Interaction report

Pygeum Africanum Extract by BulkSupplements.com Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Pygeum Africanum Extract. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Pygeum Africanum Extract, from the product label.

BulkSupplements.com

See all BulkSupplements.com products
Name
BulkSupplements.com
Street Address
7511 Eastgate Rd
City
Henderson
State
NV
ZipCode
89011
Web Address
BulkSupplements.com
Pharmacist Counseling Corner

Pygeum Africanum Extract by BulkSupplements.com: Common Questions

Does Pygeum Africanum Extract by BulkSupplements.com interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Pygeum Africanum Extract. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Pygeum Africanum Extract contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is Pygeum africanum extract used for?
It's used primarily for benign prostatic hyperplasia (BPH) — the non-cancerous swelling of the prostate that causes urinary symptoms in men. It's likely effective for that purpose. It's also been studied for Alzheimer's disease, sexual desire, psychosis, and malaria, but we don't have solid evidence for those uses yet.
Does Pygeum have side effects?
In clinical trials, some people reported nausea and abdominal pain, but these happened at about the same rate as placebo. Overall, it's generally well tolerated in the short term, though long-term safety data are limited.
Can I take Pygeum if I'm pregnant or breastfeeding?
No — Pygeum has no established safe use in pregnancy and isn't recommended during breastfeeding because there isn't enough safety data. If you're pregnant, planning to become pregnant, or nursing, talk with your doctor or pharmacist before considering this product.
How long can I safely take Pygeum?
The safety data are strongest for short-term use. Long-term safety information is limited, so it's worth discussing duration and dosing with your doctor or pharmacist before you start.
Is there anything else in this product besides Pygeum?
No — this is a single-ingredient product with just Pygeum africanum Bark Extract and no added fillers or inactive ingredients.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Pygeum Africanum Extract is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Pygeum Africanum Extract label
Go deeper

The Full Monographs Behind Pygeum Africanum Extract’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Pygeum Africanum Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Pygeum 3 references
  1. Ishani A, MacDonald R, Nelson D, et al. Pygeum africanum for the treatment of patients with benign prostatic hyperplasia: a systematic review and quantitative meta-analysis. Am J Med 2000;109:654-64.. PubMed
  2. Wilt T, Ishani A, Mac Donald R, et al. Pygeum africanum for benign prostatic hyperplasia. Cochrane Database Syst Rev 2002;CD001044.. PubMed
  3. Andro M and Riffaud J. Pygeum africanum extract for the treatment of patients with benign prostatic hyperplasia: a review of 25 years of published experience. Curr Ther Res 1995;56(8):796-817. DOI

See these in context on the Pygeum monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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