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Dietary supplement

Quina Alcohol Free Ingredients & Drug Interactions

by Hawaii Pharm

Quina Alcohol Free label
See full label image
Liquid Category: Botanical
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Quina Alcohol Free against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Quina Alcohol Free is a dietary supplement by Hawaii Pharm with 1 active ingredient. Its ingredients are commonly taken for malaria (historical/traditional), fever, leg cramps and restless legs.Based on those ingredients, 492 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Quina Bark Extract, Dry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Quina Alcohol Free by Hawaii Pharm

Ask about any prescription or over-the-counter medication and we check it for interactions with Quina Alcohol Free by Hawaii Pharm — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Quina Alcohol Free by Hawaii Pharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: quina bark extract (dry). The extract includes the alkaloids quinine and quinidine, which are the compounds responsible for the product's effects and its interactions with medications.

The liquid also contains glycerin and water as inactive ingredients.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Cinchona's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: herbal extract.
  • We looked for evidence on: Leg cramps, Muscle cramps, Malaria, digestive support, appetite stimulation.
  • The closest evidence on file: Cinchona is rated "Insufficient Reliable Evidence To Rate" for Malaria (Natural Medicines).
  • Also on file: Cinchona is rated "Insufficient Reliable Evidence To Rate" for Muscle cramps, Leg cramps.

The evidence for quina bark extract is not established in the data we hold. Our monograph lists six uses—cancer, respiratory infections, hemorrhoids, influenza, malaria, and muscle cramps—but for all of them, the rating is insufficient reliable evidence.

That means research hasn't yet built a strong enough case to say whether it works for these purposes.

The evidence, ingredient by ingredient Cinchona

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Quina bark extract carries real safety concerns you should know about. The most serious: quinine (one of its alkaloids) has been linked to rare but sometimes fatal blood disorders, including low platelet counts, clotting disorders, and hemolytic anemia with kidney failure.

Early warning signs include bleeding from the gums, nose, or GI tract, easy bruising, and small red spots on the skin. The extract can also cause a rhythm disorder called cinchonism and potentially dangerous changes to your heart's electrical activity.

More common side effects from oral use are diarrhea, nausea, ringing ears, and vomiting—especially with prolonged high doses. If you're pregnant, the safety data advises against this product because quinine may harm the pregnancy.

If you're breastfeeding, there isn't enough data to say it's safe; quinine can pass to your baby, so talk with your pharmacist or doctor about whether it's right for you.

Side effects, ingredient by ingredient Cinchona

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Cinchona.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; heart-rhythm medications.
  • For scale: 492 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Quina Alcohol Free, double-check if you're on quinidine or quinine (Major severity); QT interval-prolonging heart medications; blood thinners or antiplatelet drugs; drugs metabolized by the CYP2D6 liver enzyme; phenobarbital or carbamazepine; or antacids (all Moderate severity). These are the medication types most likely to be affected.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Major medication interactions have been identified, and safety information is well characterized.

Quina Alcohol Free is a single-ingredient product with significant interactions and real safety alerts attached to quinine. If you take any medications—especially heart, blood-thinning, or seizure drugs—you need to check them against this product first.

Pregnant people and those breastfeeding should avoid it. Talk to your pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 24, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Quina Alcohol Free, straight from the product label.

Brand Hawaii Pharm
Barcode (UPC) 840253643605
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Aug 24, 2023
DSLD ID 300755
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Quina Alcohol Free by Hawaii Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.7 mL
Maximum serving Sizes:
1 mL
Servings per container
120
UPC/BARCODE
840253643605
IngredientAmount% DV
Quina Bark Extract, Dry1156 mg--

Other ingredients: Glycerin, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Hawaii Pharm Herbal Extract Highest quality since 2008

Suggested/Recommended/Usage/Directions

Suggested use: Shake well before using. For adults add about 20-30 drops (0.7-1 mL, one full squeeze of the dropper bulb) to some juice or water, up to 4 times a day.

Precautions

Warning: We recommend to seek expert medical advice before taking.

Do not use if you are allergic to any ingredients.

Consult your physician before giving to children under 18, during pregnancy, if nursing or taking medications.

Consult your physician before giving to children under 18, during pregnancy, if nursing or taking medications.

May affect the ability to drive and operate machinery. May have contraindications, can cause side effects and adverse reactions. Do not use if seal is broken or missing.

Keep out of the reach of children!

Storage

Store in a cool dry place.

Seals/Symbols

cGMP Made in compliance with cGMP 21 CFR 111 in an FDA registered and inspected facility.

C2H5OH Alcohol free USA Made in United States of America

FDA Disclaimer Statement

This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Scan this QR-code to get 15% discount on your next purchase. Limited time deal.

Formula

Cinchona officinalis

Formulation

Only natural ingredients Purity is laboratory tested and verified

All the raw materials are gluten-free by their nature No artificial colors, flavors, or preservatives

Not tested on animals

C2H5OH Alcohol free

Made in USA, Hawaii

FDA Statement of Identity

Herbal Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Quina Alcohol Free by Hawaii Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Quina Alcohol Free label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Quina Alcohol Free by Hawaii Pharm

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.7 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.

Quina Bark Extract, Dry

Interacts with
492 drugs
1156 mg per serving Form: Cinchona officinalis Bark Extract, Dry

Cinchona bark is the natural source of quinine and has been used for centuries to treat malaria and fever, but the bark itself is not standardized and...

Quina Bark Extract, Dry monograph & interactions

Other (inactive) ingredients: Glycerin, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Quina Alcohol Free by Hawaii Pharm Drug Interactions

Want to check YOUR meds against Quina Alcohol Free?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
492Drugs
3 Major 473 Moderate 16 Minor

Ingredients driving the most interactions

Quina Bark Extract, Dry 492

Individual Drug Interactions

The ingredients in Quina Alcohol Free interact with 492 drugs. Click any drug to see the details.

1 of the 1 ingredient in Quina Alcohol Free interact with drugs. Each result below shows which ingredient is responsible. Quina Bark Extract, Dry

Each ingredient & the kinds of drugs it affects

For each ingredient in Quina Alcohol Free with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Quina Bark Extract, Dry11 drug types · 492 drugs

Quinidine

Theoretically, taking cinchona might increase plasma levels and adverse effects of quinidine.
Cinchona contains quinidine.

Likelihood Probable Evidence D
Quinine

Theoretically, taking cinchona might increase plasma levels and adverse effects of quinine.
Cinchona contains quinine.

Likelihood Probable Evidence D
Antacids

Theoretically, taking cinchona might decrease the effectiveness of antacids. Theoretically, taking antacids might also increase the risk of adverse effects from cinchona.
Some research shows that taking cinchona lowers stomach acid pH. In addition, some research shows that taking antacids might increase urinary pH. Theoretically, this may increase the amount of quinidine, a constituent of cinchona, reabsorbed in the renal tubules and increase the risk of quinidine toxicity.

Likelihood Possible Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, taking cinchona might increase the drug effects and risk of bleeding with anticoagulant and antiplatelet drugs.
In vitro evidence shows that the alkaloids quinine, quinidine, and cinchonine, constituents of cinchona, inhibit platelet aggregation.

Likelihood Possible Evidence D
Carbamazepine (Tegretol)

Theoretically, taking cinchona might increase the adverse effects of carbamazepine.
Clinical research shows that taking quinine, a constituent of cinchona, increases the peak plasma concentration and area under the curve of carbamazepine.

Likelihood Probable Evidence B
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, taking cinchona might inhibit cytochrome P450 2D6 (CYP2D6) and increase levels of drugs metabolized by this enzyme.
Quinidine, a constituent of cinchona, inhibits CYP2D6-mediated metabolism in humans.

Likelihood Possible Evidence D
Digoxin (Lanoxin)

Theoretically, taking cinchona might increase serum levels of digoxin.
Quinine and quinidine, which are constituents of cinchona, decrease clearance of digoxin and increase serum digoxin levels in humans.

Likelihood Possible Evidence D
Phenobarbital (Luminal)

Theoretically, taking cinchona might increase the adverse effects of phenobarbital.
Clinical research shows that taking quinine, a constituent of cinchona, increases the peak plasma concentration and area under the curve of phenobarbital.

Likelihood Probable Evidence D
Qt Interval-Prolonging Drugs

Theoretically, taking cinchona with other QT interval-prolonging drugs might cause an additive effect and increase the risk of ventricular arrhythmias.
Quinidine and quinine, which are constituents of cinchona, prolong the QT interval.

Likelihood Possible Evidence D
H2-Blockers

Theoretically, taking cinchona might decrease the effectiveness of H2-blockers.
Some research shows that taking cinchona lowers stomach acid pH.

Likelihood Possible Evidence D
Proton Pump Inhibitors (Ppis)

Theoretically, taking cinchona might decrease the effectiveness of PPIs.
Some research shows that taking cinchona lowers stomach acid pH.

Likelihood Possible Evidence D
Quina Bark Extract, Dry full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Quina Alcohol Free, from the product label.

Hawaii Pharm

See all Hawaii Pharm products
Name
Hawaii Pharm LLC
Street Address
510 Sumner St. Ste. 613
City
Honolulu
State
HI
ZipCode
96817
Phone Number
888-854-2924
Web Address
www.hawaiipharm.com
Pharmacist Counseling Corner

Quina Alcohol Free by Hawaii Pharm: Common Questions

Does Quina Alcohol Free by Hawaii Pharm interact with any medications?
Yes. Based on its ingredients, Quina Alcohol Free has a known interaction with 492 medications, including 3 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Quina Alcohol Free contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is quina bark, and what is it used for?
Quina bark extract contains the alkaloids quinine and quinidine. Traditional uses include cancer, respiratory infections, hemorrhoids, influenza, malaria, and muscle cramps, but reliable evidence for any of these isn't established in our data.
Can I take this if I'm pregnant or breastfeeding?
No, if you're pregnant—the quinine in cinchona may harm your pregnancy, so it should be avoided. If you're breastfeeding, safety isn't established and quinine can pass to your baby; talk with your pharmacist or doctor about whether it's right for you.
What are the most common side effects?
From oral use: diarrhea, nausea, ringing ears, and vomiting. These are more likely with prolonged high doses. Rare serious effects include heart rhythm problems, blood disorders, and kidney issues.
Does this product contain any fillers or inactive ingredients?
Yes. The inactive ingredients are glycerin and water. There is one active ingredient: quina bark extract.
Why are there so many medication interactions listed?
Quinine and quinidine—alkaloids naturally present in quina bark—are potent compounds that affect how your liver metabolizes drugs and how your heart functions. That's why they interact with a broad range of medications across different drug categories.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Quina Alcohol Free is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Quina Alcohol Free label
Go deeper

The Full Monographs Behind Quina Alcohol Free’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Cinchona

Interacts with 492 drugs

Cinchona bark is the natural source of quinine and has been used for centuries to treat malaria and fever, but the bark itself is not standardized and can be unpredictable and risky. Modern...

Read the full Cinchona monograph →
Sources

Sources & How We Checked

Quina Alcohol Free's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Cinchona 15 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Wichtl MW. Herbal Drugs and Phytopharmaceuticals. Ed. N.M. Bisset. Stuttgart: Medpharm GmbH Scientific Publishers, 1994.
  3. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  4. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  5. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  6. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  7. Holt GA. Food & Possible Interactions with Drugs: Revised and Expanded Ed. Chicago, IL: Precept Press, 1998.
  8. Hardman JG, Limbird LL, Molinoff PB, eds. Goodman and Gillman's The Pharmacological Basis of Therapeutics, 9th ed. New York, NY: McGraw-Hill, 1996.
  9. Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
  10. Amabeoku GJ, Chikuni O, Akino C, Mutetwa S. Pharmacokinetic interaction of single doses of quinine and carbamazepine, phenobarbitone and phenytoin in healthy volunteers. East Afr Med J 1993;70:90-3.
  11. Shah BH, Nawaz Z, Virani SS, Ali IQ, Saeed SA, Gilani AH.The inhibitory effect of cinchonine on human platelet aggregation due to blockade of calcium influx. Biochem Pharmacol 1998;56:955-60. PubMed
  12. US Food and Drug Administration notice: Drug products containing quinine - enforcement action dates. Docket # 2006N-0476. Federal Register 2006 (December 15);71 (241): 75557-60.
  13. FDA Drug Safety Communication: New risk management plan and patient medication guide for Qualaquin (quinine sulfate). 07-08-2010. https://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/ucm218202 (accessed 02/18/17).
  14. Dooms-Goossens A, Deveylder H, Duron C, et al. Airborne contact urticaria due to cinchona. Contact Dermatitis 1986;15(4):258. PubMed
  15. Bramer SL, Suri A. Inhibition of CYP2D6 by quinidine and its effects on the metabolism of cilostazol. Clin Pharmacokinet. 1999;37 Suppl 2:41-51. PubMed

See these in context on the Cinchona monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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