R-ALA Ingredients & Drug Interactions
What is this page for?
First and foremost: checking R-ALA against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
R-ALA is a dietary supplement by New You Vitamins with 1 active ingredient. Its ingredients are commonly taken for diabetic nerve pain (neuropathy), blood sugar support in diabetes, antioxidant support.Based on those ingredients, 263 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are R-Alpha Proprietary Blend. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against R-ALA by New You Vitamins
Ask about any prescription or over-the-counter medication and we check it for interactions with R-ALA by New You Vitamins — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of R-ALA by New You Vitamins
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.
Why this rating?
- The label discloses an exact amount for 0 of its 1 active ingredient.
- “R-Alpha Proprietary Blend” is a proprietary blend — the label gives one combined amount (200 mg) without saying how much of each component you get.
The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.
Why this rating?
- 1 of the 1 matched ingredient can interact with medications — Alpha-lipoic Acid.
- The most serious interaction on file is rated Moderate.
- Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; cancer treatments; diabetes medications.
- For scale: 263 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.
Why this rating?
- We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
- Pregnancy & breastfeeding safety ratings cover 1 of 1.
- General safety write-ups exist for 1 of 1.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2015.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about R-ALA, straight from the product label.
| Brand | New You Vitamins |
|---|---|
| Barcode (UPC) | 609408293498 |
| Net contents | 90 Capsule(s) |
| Market status | Off market |
| Date entered into DSLD | Jul 24, 2015 |
| DSLD ID | 47756 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for R-ALA by New You Vitamins, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| R-Alpha Proprietary Blend | 200 mg | -- |
| R-ALA | 0 NP | -- |
Other ingredients: Gelatin, MC Cellulose, Stearic Acid, Magnesium Stearate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
This product contains no dairy, egg, fish, peanuts, gluten, shellfish, wheat, yeast, sugars, flavors or preservatives.
Seals/Symbols
GUARANTEE 100% SATISFACTION GUARANTEE
MADE WITH NATURAL INGREDIENT
GMP GOOD MANUFACTURING PRACTICE
MADE IN USA
New You Vitamins Premium Nutrition.Optimum Health
General
RAL-CN-89
General Statements
Pharma grade 100% bioavailability
Formula
Alpha Lipoic Acid Complex
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Directions: As a dietary supplement, take 1 capsule three times daily with meals.
Precautions
Warning: Consult your doctor before use if you have, or have had, any health condition or if you are taking any medications or remedies including OTC medications, or are planning any medical procedure.
Discontinue use and consult your doctor if any adverse reactions occur, such as gastrointestinal discomfort or any allergic reaction.
Not intended for use by persons under the age of 18.
FDA Disclaimer Statement
This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
R-ALA by New You Vitamins label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in R-ALA by New You Vitamins
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.
R-Alpha Proprietary Blend
Interacts with263 drugs
Alpha-lipoic acid (ALA) is an antioxidant made naturally by the body and found in small amounts in foods. It is most studied for diabetic nerve pain,...
R-Alpha Proprietary Blend monograph & interactions- › R-ALA
Other (inactive) ingredients: Gelatin, MC Cellulose, Stearic Acid, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.
R-ALA by New You Vitamins Drug Interactions
R-ALA contains a single active ingredient, and it has known interactions with 263 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against R-ALA?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in R-ALA interact with 263 drugs. Click any drug to see the details.
1 of the 1 ingredient in R-ALA interact with drugs. Each result below shows which ingredient is responsible. R-Alpha Proprietary Blend
AbciximabReoPro
How Abciximab interacts with R-ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-ala + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with R-ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-ala + Abrocitinib interactionAcenocoumarolSintrom
How Acenocoumarol interacts with R-ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-ala + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with R-ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-ala + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with R-ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-ala + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with R-ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-ala + Acetaminophen, Ibuprofen interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with R-ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-ala + Acetylsalicylic Acid interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with R-ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-ala + Alteplase, Tpa interactionAltretamineHexalen
How Altretamine interacts with R-ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alaAlkylating Agents Moderate
Interaction Summary
Theoretically, the antioxidant effects of alpha-lipoic acid might alter the effectiveness of alkylating agents.
Read the full R-ala + Altretamine interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with R-ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-ala + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with R-ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-ala + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAnacaulase-bcdbNexoBrid
How Anacaulase-bcdb interacts with R-ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-ala + Anacaulase-bcdb interactionAnagrelideAgrylin
How Anagrelide interacts with R-ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-ala + Anagrelide interactionAnisindioneMiradon
How Anisindione interacts with R-ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-ala + Anisindione interactionAntithrombin IiiThrombate III
How Antithrombin Iii interacts with R-ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-ala + Antithrombin Iii interactionApixabanEliquis
How Apixaban interacts with R-ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-ala + Apixaban interactionArgatrobanArgatroban
How Argatroban interacts with R-ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-ala + Argatroban interactionAspirinAngettes 75, ASA, Asaphen, Aspirin, Caprin, Cartia +8 more
How Aspirin interacts with R-ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-ala + Aspirin interactionAspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #3
How Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interacts with R-ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-ala + Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interactionAspirin, ButalbitalAxotal
How Aspirin, Butalbital interacts with R-ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-ala + Aspirin, Butalbital interactionAspirin, Butalbital, CaffeineFiorinal
How Aspirin, Butalbital, Caffeine interacts with R-ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-ala + Aspirin, Butalbital, Caffeine interactionAspirin, Butalbital, Caffeine, Codeine PhosphateFiorinal w/ Codeine
How Aspirin, Butalbital, Caffeine, Codeine Phosphate interacts with R-ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-ala + Aspirin, Butalbital, Caffeine, Codeine Phosphate interactionAspirin, Butalbital, Caffeine, PhenacetinMarnal
How Aspirin, Butalbital, Caffeine, Phenacetin interacts with R-ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-ala + Aspirin, Butalbital, Caffeine, Phenacetin interactionAspirin, CaffeineAnacin
How Aspirin, Caffeine interacts with R-ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-ala + Aspirin, Caffeine interactionAspirin, Caffeine, Codeine PhosphateAnacin w/ Codeine
How Aspirin, Caffeine, Codeine Phosphate interacts with R-ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-ala + Aspirin, Caffeine, Codeine Phosphate interactionAspirin, Caffeine, Dihydrocodeine BitartrateSynalgos DC
How Aspirin, Caffeine, Dihydrocodeine Bitartrate interacts with R-ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-ala + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAspirin, Caffeine, Dover's PwdAcedoval, Dovacet
How Aspirin, Caffeine, Dover's Pwd interacts with R-ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-ala + Aspirin, Caffeine, Dover's Pwd interactionAspirin, Caffeine, HydrocodoneDamason-P
How Aspirin, Caffeine, Hydrocodone interacts with R-ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-ala + Aspirin, Caffeine, Hydrocodone interactionAspirin, Caffeine, Isobutylallylbarbituric Acid, PhenacetinLanorinal
How Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin interacts with R-ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-ala + Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin interactionAspirin, Caffeine, OrphenadrineInvagesic, Invagesic Forte, Norgesic, Norgesic Forte, Orphengesic, Orphengesic Forte
How Aspirin, Caffeine, Orphenadrine interacts with R-ALA — through 1 ingredient. Tap an ingredient for the detail:
R-alaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full R-ala + Aspirin, Caffeine, Orphenadrine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in R-ALA with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
R-Alpha Proprietary Blend
Alkylating Agents
Theoretically, the antioxidant effects of alpha-lipoic acid might alter the effectiveness of alkylating agents.
The use of antioxidants like alpha-lipoic acid during chemotherapy is controversial. There are concerns that antioxidants could reduce the activity of chemotherapy drugs that generate free radicals. However, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that might interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effect, if any, antioxidants such as alpha-lipoic acid have on chemotherapy. Advise patients to consult their oncologist before using alpha-lipoic acid.
Anticoagulant/Antiplatelet Drugs
Theoretically, alpha-lipoic acid may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro, alpha-lipoic acid inhibits platelet aggregation.
Antitumor Antibiotics
Theoretically, the antioxidant effects of alpha-lipoic acid might alter the effectiveness of antitumor antibiotics.
The use of antioxidants like alpha-lipoic acid during chemotherapy is controversial. There are concerns that antioxidants could reduce the activity of antitumor antibiotic drugs, which work by generating free radicals. However, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that might interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effect, if any, antioxidants such as alpha-lipoic acid have on chemotherapy involving antitumor antibiotics. Advise patients to consult their oncologist before using alpha-lipoic acid.
Thyroid Hormone
Theoretically, alpha-lipoic acid might decrease the effects of thyroid hormone drugs.
Animal research suggests that co-administration of thyroxine with alpha-lipoic acid reduces conversion into the active T3 form.
Antidiabetes Drugs
Theoretically, taking alpha-lipoic acid with antidiabetes drugs might increase the risk of hypoglycemia.
Although some small clinical studies have suggested that alpha-lipoic acid can lower blood glucose levels, larger clinical studies in patients with diabetes have shown no clinically meaningful effect. Additionally, co-administration of single doses of alpha-lipoic acid and glyburide or acarbose did not cause detectable drug interactions in healthy volunteers.
Brand information
Manufacturer and brand details for R-ALA, from the product label.
New You Vitamins
See all New You Vitamins products- Name
- NewYouVitamins.com
- City
- Orlando
- State
- FL
- ZipCode
- 32824
- Web Address
- NewYouVitamins.com
R-ALA by New You Vitamins: Common Questions
Does R-ALA by New You Vitamins interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if R-ALA is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind R-ALA’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
R-ALA's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 48 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Alpha-lipoic Acid 48 references
- Labriola D, Livingston R. Possible interactions between dietary antioxidants and chemotherapy. Oncology 1999;13:1003-8.
- Anon. Alpha-lipoic acid. Altern Med Rev 1998;3:308-10.
- Konrad T, Vicini P, Kusterer K, et al. Alpha-lipoic acid treatment decreases serum lactate and pyruvate concentrations and improves glucose effectiveness in lean and obese patients with Type 2 diabetes. Diabetes Care 1999;22:280-7. PubMed
- Ziegler D, Hanefeld M, Ruhnau KJ, et al. Treatment of symptomatic diabetic peripheral neuropathy with the antioxidant alpha-lipoic acid: A 3-week, multicentre randomized controlled trial (ALADIN Study). Diabetologia 1995;38:1425-33.
- Gleiter CH, Schreeb KH, Freudenthaler S, et al. Lack of interaction between thioctic acid, glibenclamide and acarbose. Br J Clin Pharmacol 1999;48:819-25. PubMed
- Jacob S, Henriksen EJ, Tritschler HJ, et al. Improvement of insulin-stimulated glucose-disposal in type 2 diabetes after repeated parenteral administration of thioctic acid. Exp Clin Endocrinol Diabet 1996;104:284-8. PubMed
- Jacob S, Henriksen EJ, Schiemann AL, et al. Enhancement of glucose disposal in patients with type 2 diabetes by alpha-lipoic acid. Arzneimittelforschung 1995;45:872-4.
- Jacob S, Ruus P, Hermann R, et al. Oral administration of RAC-alpha-lipoic acid modulates insulin sensitivity in patients with type-2 diabetes mellitus: a placebo-controlled, pilot trial. Free Rad Biol Med 1999;27:309-14.
- Segermann J, Hotze A, Ulrich H, Rao GS. Effect of alpha-lipoic acid on the peripheral conversion of thyroxine to triiodothyronine and on serum lipid-, protein- and glucose levels. Arzneimittelforschung 1991;41:1294-8.
- Beitner H. Randomized, placebo controlled, double-blind study on the clinical efficacy of a cream containing 5% alpha-lipoic acid related to photoaging of facial skin. Br J Dermatol 2003;149:841-9.
- Ziegler D, Nowak H, Kempler P, et al. Treatment of symptomatic diabetic polyneuropathy with the antioxidant alpha-lipoic acid: A meta-analysis. Diabet Med 2004;21:114-21.
- Prasad KN. Rationale for using high-dose multiple dietary antioxidants as an adjunct to radiation therapy and chemotherapy. J Nutr 2004;134:3182S-3S. PubMed
- Conklin KA. Cancer chemotherapy and antioxidants. J Nutr 2004;134:3201S-3204S. PubMed
- Vincent HK, Bourguignon CM, Vincent KR, Taylor AG. Effects of alpha-lipoic acid supplementation in peripheral arterial disease: a pilot study. J Alt Complement Med 2007;13:577-84. PubMed
- Furukawa N, Miyamura N, Nishida K, et al. Possible relevance of alpha lipoic acid contained in a health supplement in a case of insulin autoimmune syndrome. Diabetes Res Clin Pract 2007;75:366-7. PubMed
- Ziegler D., Ametov A., Barinov A., Dyck P. J., Gurieva I., Low P. A., Munzel U., Yakhno N., Raz I., Novosadova M., Maus J., Samigullin, R. Oral treatment with alpha-lipoic acid improves symptomatic diabetic polyneuropathy: the SYDNEY 2 trial. Diabetes Car
- Gu X. M., Zhang S. S., Wu J. C., Tang Z. Y., Lu Z. Q., Li H., Liu C., Chen L., Ning, G. [Efficacy and safety of high-dose a-lipoic acid in the treatment of diabetic polyneuropathy]. Zhonghua Yi Xue Za Zhi 2010;90(35):2473-2476.
- Porasuphatana S., Suddee S., Nartnampong A., Konsil J., Harnwong B., Santaweesuk A. Glycemic and oxidative status of patients with type 2 diabetes mellitus following oral administration of alpha-lipoic acid: a randomized double-blinded placebo-controlled
- Ansar H., Mazloom Z., Kazemi F., Hejazi N. Effect of alpha-lipoic acid on blood glucose, insulin resistance and glutathione peroxidase of type 2 diabetic patients. Saudi Med J 2011;32(6):584-588. DOI
- de Oliveira A. M., Rondó P. H., Luzia L. A., D'Abronzo F. H., Illison V. K. The effects of lipoic acid and a-tocopherol supplementation on the lipid profile and insulin sensitivity of patients with type 2 diabetes mellitus: a randomized, double-blind, pla
- Mazloom Z., Ansar H. The Effect of Alpha-Lipoic Acid on Blood Pressure in Type 2 Diabetics. Iranian Journal of Endocrinology and Metabolism 2009;11(3):245-250.
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