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Dietary supplement

D-Ribose Ingredients & Drug Interactions

by New You Vitamins

D-Ribose label
See full label image
Capsule Category: Fiber And Other Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking D-Ribose against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

D-Ribose is a dietary supplement by New You Vitamins with 1 active ingredient. Its ingredients are commonly taken for energy and fatigue, athletic performance and recovery, fibromyalgia symptoms.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are D-Ribose. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against D-Ribose by New You Vitamins

Ask about any prescription or over-the-counter medication and we check it for interactions with D-Ribose by New You Vitamins — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of D-Ribose by New You Vitamins

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 23, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

New You Vitamins D-Ribose contains one active ingredient: D-ribose, a five-carbon sugar your body uses to make energy at the cellular level. The capsule also holds gelatin and microcrystalline cellulose (a common binder and filler).

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Ribose's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: ATP energy production and cellular energy support.
  • We looked for evidence on: Athletic performance, Chronic fatigue syndrome (CFS), Fibromyalgia, Congestive heart failure (CHF), Coronary heart disease (CHD), Coronary artery bypass graft (CABG) surgery — and 4 related terms.
  • The closest evidence on file: Ribose is rated "Possibly Ineffective" for Athletic performance (Natural Medicines).
  • Also on file: Ribose is rated "Possibly Ineffective" for McArdle disease.
  • Also on file: Ribose is rated "Insufficient Reliable Evidence To Rate" for Coronary heart disease (CHD), Chronic fatigue syndrome (CFS), Congestive heart failure (CHF), Fibromyalgia, and more.

The evidence for D-ribose is mixed and limited. For athletic performance and McArdle disease, studies suggest it's probably ineffective.

For restless legs syndrome, muscle soreness, congestive heart failure, and recovery after coronary artery bypass surgery, we don't have enough reliable data to say whether it works or doesn't.

The evidence, ingredient by ingredient Ribose

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

D-ribose is generally well tolerated for short-term use — up to about a month in studies — but long-term safety hasn't been well studied. The main concern is low blood sugar (hypoglycemia), which can happen on its own or be worsened if you're also on blood-sugar-lowering medications.

Common side effects from oral use include diarrhea, stomach upset, headache, nausea, and anxiety; a few people report lightheadedness, increased appetite, or hyperanxiety. Lowering the dose has resolved nausea and anxiety in some cases.

During pregnancy and breastfeeding, there isn't enough safety data, so it's best avoided. Talk with your doctor or pharmacist about whether it's right for you in these situations.

Side effects, ingredient by ingredient Ribose

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Ribose.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before taking this product if you take insulin or any antidiabetes medication (such as metformin, sulfonylureas, or newer drugs). Both drug classes carry a Moderate risk of increased low blood sugar when combined with ribose.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

D-ribose may appeal to people exploring options for heart health or muscle recovery, but the evidence for most uses is weak or unclear. The bigger practical concern is blood sugar — especially if you take insulin or antidiabetes drugs.

Before you start, check your exact medications with your doctor or pharmacist to make sure this supplement won't interfere.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about D-Ribose, straight from the product label.

Brand New You Vitamins
Barcode (UPC) 609408293450
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Jul 24, 2015
DSLD ID 47630
Product type Fiber And Other Nutrients
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for D-Ribose by New You Vitamins, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
30
UPC/BARCODE
609408293450
IngredientAmount% DV
D-Ribose1200 mg--

Other ingredients: Gelatin, Microcrystalline Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

This product contains no dairy, egg, fish, peanuts, gluten, shellfish, wheat, yeast, sugars, flavors or preservatives.

Seals/Symbols

GUARANTEE 100%

MADE WITH NATURAL INGREDIENT

GMP GOOD MANUFACTURING PRACTICE

MADE IN USA

General

DR1-CN-85

General Statements

Premium Nutrition. Optimum Health

Fuels natural ATP energy production

Formula

ATP energy 100% pure Ribose

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take 3 capsules daily, prior to exercise.

Precautions

Warning: Consult your doctor before use if you have, or have had, any health condition or if you are taking any medications or remedies including OTC medications, or are planning any medical procedure.

Discontinue use and consult your doctor if any adverse reactions occur, such as gastrointestinal discomfort or any allergic reaction.

Not intended for use by persons under the age of 18.

FDA Disclaimer Statement

*This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

D-Ribose by New You Vitamins label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

D-Ribose label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in D-Ribose by New You Vitamins

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size3 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

D-Ribose

Interacts with
86 drugs
1200 mg per serving

Ribose (D-ribose) is a simple sugar your body makes naturally and uses to build energy molecules like ATP. Some people take it for fatigue, fibromyalg...

D-Ribose monograph & interactions

Other (inactive) ingredients: Gelatin, Microcrystalline Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

D-Ribose by New You Vitamins Drug Interactions

Want to check YOUR meds against D-Ribose?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

D-Ribose 86

Individual Drug Interactions

The ingredients in D-Ribose interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in D-Ribose interact with drugs. Each result below shows which ingredient is responsible. D-Ribose

Each ingredient & the kinds of drugs it affects

For each ingredient in D-Ribose with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

D-Ribose2 drug types · 86 drugs

Antidiabetes Drugs

Theoretically, taking ribose in combination with antidiabetes drugs might increase the risk of hypoglycemia.
In clinical research, ribose decreases serum glucose levels in a dose-dependent manner.

Likelihood Probable Evidence B
Insulin

Theoretically, taking ribose with insulin could increase the hypoglycemic effect of insulin.
In clinical pharmacokinetic studies, oral administration of ribose modestly increased serum insulin levels.

Likelihood Possible Evidence B
D-Ribose full monograph & interactions
The maker

Brand information

Manufacturer and brand details for D-Ribose, from the product label.

New You Vitamins

See all New You Vitamins products
Name
NewYouVitamins.com
City
Orlando
State
FL
ZipCode
32824
Web Address
NewYouVitamins.com
Pharmacist Counseling Corner

D-Ribose by New You Vitamins: Common Questions

Does D-Ribose by New You Vitamins interact with any medications?
Yes. Based on its ingredients, D-Ribose has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
D-Ribose contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will D-ribose help my athletic performance?
The studies we have suggest it's probably not effective for athletic performance. If that's your main reason for considering it, this product may not deliver what you're looking for.
What are the most common side effects?
From oral use, the most frequent side effects are diarrhea, stomach discomfort, headache, nausea, and low blood sugar. Anxiety, lightheadedness, and increased appetite have also been reported. In some people, lowering the dose has resolved the nausea and anxiety.
Is it safe to take D-ribose long-term?
It's generally well tolerated for short-term use — up to about a month in studies — but long-term safety hasn't been well studied. Talk with your doctor or pharmacist about whether ongoing use is right for you.
Can I take this if I'm pregnant or breastfeeding?
There isn't enough safety data to know either way. The data we have advises against it during both pregnancy and breastfeeding. Talk with your doctor or pharmacist for personalized advice.
What's in the capsule besides D-ribose?
Each capsule also contains gelatin and microcrystalline cellulose, which are inactive ingredients that help hold the supplement together.
Does D-ribose work for heart failure or muscle soreness?
We don't have enough reliable evidence to say whether it helps with congestive heart failure, muscle soreness, or recovery after bypass surgery. More research would be needed to know.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if D-Ribose is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

D-Ribose label
Go deeper

The Full Monographs Behind D-Ribose’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Ribose

Interacts with 86 drugs

Ribose (D-ribose) is a simple sugar your body makes naturally and uses to build energy molecules like ATP. Some people take it for fatigue, fibromyalgia, exercise recovery, or heart conditio...

Read the full Ribose monograph →
Sources

Sources & How We Checked

D-Ribose's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Ribose 8 references
  1. Segal S, Foley J. The metabolism of D-ribose in man. J Clin Invest 1958;37:719-35. PubMed
  2. Perlmutter NS, Wilson RA, Angello DA, et al. Ribose facilitates thallium-201 redistribution in patients with coronary artery disease. J Nucl Med 1991;32:193-200.
  3. Hegewald MG, Palac RT, Angello DA, et al. Ribose infusion accelerates thallium redistribution with early imaging compared with late 24-hour imaging without ribose. J Am Coll Cardiol 1991;18:1671-81. PubMed
  4. Pliml W, von Arnim T, Stalein A, et al. Effects of ribose on excercise-induced ischaemia in stable coronary artery disease. Lancet 1992;340:507-10.
  5. Burke ER. D-Ribose What You Need To Know. Garden City Park, NY: Avery Publishing Group 1999;1-43.
  6. Gross M, Reiter S, Zollner N. Metabolism of D-ribose administered continuously to healthy persons and to patients with myoadenylate deaminase deficiency. Klin Wochenschr 1989;67:1205-13. PubMed
  7. Teitelbaum JE, Johnson C, St Cyr J. The use of D-ribose in chronic fatigue syndrome and fibromyalgia: a pilot study. J Altern Complement Med 2006;12:857-62. PubMed
  8. Thompson J, Neutel J, Homer K, Tempero K, Shah A, Khankari R. Evaluation of D-ribose pharmacokinetics, dose proportionality, food effect, and pharmacodynamics after oral solution administration in healthy male and female subjects. J Clin Pharmacol 2014;54 PubMed

See these in context on the Ribose monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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