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Dietary supplement

GABA-Mass Ingredients & Drug Interactions

by New You Vitamins

GABA-Mass label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking GABA-Mass against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

GABA-Mass is a dietary supplement by New You Vitamins with 1 active ingredient. Its ingredients are commonly taken for anxiety and stress, sleep problems, relaxation.Based on those ingredients, 419 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Gamma Amino Butyric Acid. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against GABA-Mass by New You Vitamins

Ask about any prescription or over-the-counter medication and we check it for interactions with GABA-Mass by New You Vitamins — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of GABA-Mass by New You Vitamins

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 30, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

GABA-Mass contains one active ingredient: gamma amino butyric acid (GABA), a naturally occurring compound in your brain that plays a role in relaxation and sleep. The product also includes gelatin and microcrystalline cellulose as inactive ingredients—the capsule material and a binder that help hold the supplement together.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Gamma-aminobutyric Acid (gaba)'s own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Muscle growth and stamina.
  • We looked for evidence on: Athletic performance, Muscle strength, Exercise performance, Endurance.
  • The closest evidence on file: Gamma-aminobutyric Acid (gaba) is rated "Insufficient Reliable Evidence To Rate" for Athletic performance (Natural Medicines).

The evidence for GABA supplements is inconclusive. The data we hold rates it as having insufficient reliable evidence for anxiety, attention deficit-hyperactivity disorder (ADHD), athletic performance, chronic bronchitis, and cerebral palsy.

In other words, we don't have strong enough studies to say whether it works for any of these uses. If you're considering it for a specific condition, that's a good conversation to have with your doctor or pharmacist.

The evidence, ingredient by ingredient Gamma-aminobutyric Acid (gaba)

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Orally, GABA is generally well tolerated in the short term, though long-term safety hasn't been well studied. Common side effects in trials include drowsiness, stomach upset, minor throat burning, muscle weakness, and nausea.

One isolated case reported temporary loss of menstruation when GABA was combined with phosphatidylserine. The safety information available is limited, so this is a supplement to use cautiously and only if your doctor advises it.

There isn't enough data on safety during pregnancy; avoid it while breastfeeding unless your doctor says otherwise.

Side effects, ingredient by ingredient Gamma-aminobutyric Acid (gaba)

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Gamma-aminobutyric Acid (gaba).
  • The most serious interaction on file is rated Moderate.
  • For scale: 419 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking GABA-Mass, double-check with your doctor or pharmacist if you're on blood pressure medications (antihypertensives)—GABA may lower your blood pressure too much. Also flag any central nervous system depressants (sedatives, sleep aids, narcotic pain relievers) you take, since their combined sedative effect is unclear but theoretically possible.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

GABA-Mass is for someone curious about GABA supplementation who doesn't take blood pressure medications or CNS depressants—and even then, evidence for its effectiveness is thin. If you take any prescription medication, especially for blood pressure or anxiety, talk with your doctor or pharmacist before adding this to your routine.

The long-term safety picture isn't clear, so this isn't a set-it-and-forget-it supplement.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about GABA-Mass, straight from the product label.

Brand New You Vitamins
Barcode (UPC) 628586386792
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Jul 24, 2015
DSLD ID 47635
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for GABA-Mass by New You Vitamins, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
45
UPC/BARCODE
628586386792
IngredientAmount% DV
Gamma Amino Butyric Acid900 mg--

Other ingredients: Gelatin, Microcrystalline Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

This product contains no dairy, egg, fish, peanuts, gluten, shellfish, wheat, yeast, sugars, flavors or preservatives.

Seals/Symbols

GUARANTEE 100% SATISFACTION GUARANTEE

MADE WITH NATURAL INGREDIENT

GMP GOOD MANUFACTURING PRACTICE

MADE IN USA

New You Vitamins Premium Nutrition.Optimum Health

General

GM01 - C12

General Statements

Muscle growth and stamina

~ Natural support

Formula

~ Gamma Aminobutyric Acid (GABA)

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Take two capsules daily, preferably at bedtime or as recommended by a health care professional.

Precautions

Warning: Consult your doctor before use if you have, or have had, any health condition or if you are taking any medications or remedies including OTC medications, or are planning any medical procedure.

Discontinue use and consult your doctor if any adverse reactions occur, such as gastrointestinal discomfort or any allergic reaction.

Not intended for use by persons under the age of 18.

FDA Disclaimer Statement

*This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

GABA-Mass by New You Vitamins label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

GABA-Mass label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in GABA-Mass by New You Vitamins

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container45 Amounts shown are per serving.

Gamma Amino Butyric Acid

Interacts with
419 drugs
900 mg per serving

GABA is a calming chemical messenger (neurotransmitter) that your body makes on its own, and it is sold as a supplement for stress, anxiety, and sleep...

Gamma Amino Butyric Acid monograph & interactions

Other (inactive) ingredients: Gelatin, Microcrystalline Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

GABA-Mass by New You Vitamins Drug Interactions

Want to check YOUR meds against GABA-Mass?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
419Drugs
172 Moderate 247 Minor

Ingredients driving the most interactions

Gamma Amino Butyric Acid 419

Individual Drug Interactions

The ingredients in GABA-Mass interact with 419 drugs. Click any drug to see the details.

1 of the 1 ingredient in GABA-Mass interact with drugs. Each result below shows which ingredient is responsible. Gamma Amino Butyric Acid

Each ingredient & the kinds of drugs it affects

For each ingredient in GABA-Mass with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Gamma Amino Butyric Acid2 drug types · 419 drugs

Antihypertensive Drugs

Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Some clinical research shows that GABA can decrease blood pressure in patients with hypertension.

Likelihood Possible Evidence B
Cns Depressants

Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants. However, it is unclear if this concern is clinically relevant.
Endogenous GABA has well-established relaxant effects and GABA(A) receptors have an established physiological role in sleep. However, the effects of GABA supplements are unclear, as it is unknown whether exogenous GABA crosses the blood-brain barrier. Although there have been limited reports of drowsiness or tiredness with GABA supplements, these effects have not been widely reported in clinical studies. Additionally, intravenous GABA 0.1-1 mg/kg has been shown to induce anxiety in a dose-dependent manner.

Likelihood Unlikely Evidence D
Gamma Amino Butyric Acid full monograph & interactions
The maker

Brand information

Manufacturer and brand details for GABA-Mass, from the product label.

New You Vitamins

See all New You Vitamins products
Name
NewYouVitamins.com
City
Orlando
State
FL
ZipCode
32824
Web Address
NewYouVitamins.com
Pharmacist Counseling Corner

GABA-Mass by New You Vitamins: Common Questions

Does GABA-Mass by New You Vitamins interact with any medications?
Yes. Based on its ingredients, GABA-Mass has a known interaction with 419 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
GABA-Mass contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is GABA and what's it supposed to do?
GABA (gamma amino butyric acid) is a chemical messenger in your brain that helps promote relaxation and sleep. GABA-Mass provides it as a supplement, though the evidence that oral GABA actually works for anxiety, ADHD, athletic performance, or other conditions is not strong enough for us to say one way or the other.
What are the most common side effects?
When taken by mouth, the most common side effects people reported in studies were drowsiness, nausea, stomach upset, minor throat burning, and muscle weakness. Most people tolerate it without trouble in the short term, but long-term safety hasn't been carefully studied.
Can I take this while pregnant or breastfeeding?
There isn't enough safety data to know either way during pregnancy. For breastfeeding, the available information advises against it unless your doctor says otherwise. Talk with your doctor or pharmacist for personalized advice based on your situation.
Is this safe to take long-term?
GABA appears to be well tolerated in the short term, but long-term safety hasn't been well studied. If you're thinking about taking it regularly, that's worth discussing with your doctor or pharmacist.
What's in the capsule besides GABA?
The capsule itself is gelatin, and microcrystalline cellulose is included as a binder to hold everything together. These are common inactive ingredients in supplements.
Will this interact with my blood pressure medication?
Possibly. GABA may lower blood pressure, so taking it alongside blood pressure medications could theoretically push your pressure too low. Check with your doctor or pharmacist about your specific medications before you start.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

GABA-Mass label
Go deeper

The Full Monographs Behind GABA-Mass’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Gamma-aminobutyric Acid (gaba)

Interacts with 419 drugs

GABA is a calming chemical messenger (neurotransmitter) that your body makes on its own, and it is sold as a supplement for stress, anxiety, and sleep. The science behind oral GABA supplemen...

Read the full Gamma-aminobutyric Acid (gaba) monograph →
Sources

Sources & How We Checked

GABA-Mass's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Gamma-aminobutyric Acid (gaba) 12 references
  1. Cavagnini F, Invitti C, Pinto M, et al. Effect of acute and repeated administration of gamma aminobutyric acid (GABA) on growth hormone and prolactin secretion in man. Acta Endocrinol (Copenh) 1980;93:149-54.
  2. Nurnberger JI Jr, Berrettini WH, Simmons-Alling S, et al. Intravenous GABA administration is anxiogenic in man. Psychiatry Res 1986;19:113-7. PubMed
  3. Gershman RN, Vasilenko MA, Iliushina GG, et al. [Gammalon in the rehabilitation in infantile cerebral palsy]. Pediatr.Akus.Ginekol. 1977;(6):26-7.
  4. Loeb C, Benassi E, Bo, GP, et al. Preliminary evaluation of the effect of GABA and phosphatidylserine in epileptic patients. Epilepsy Res. 1987;1:209-12 . PubMed
  5. Inoue K, Shirai T, Ochiai H, et al. Blood-pressure-lowering effect of a novel fermented milk containing gamma-aminobutyric acid (GABA) in mild hypertensives. Eur J Clin Nutr 2003;57:490-95.
  6. ELLIOTT, K. A. and JASPER, H. H. Gammaaminobutyric acid. Physiol Rev. 1959;39(2):383-406.
  7. Winsky-Sommerer, R. Role of GABAA receptors in the physiology and pharmacology of sleep. Eur.J.Neurosci. 2009;29(9):1779-1794.
  8. Meldrum, B. S. GABAergic mechanisms in the pathogenesis and treatment of epilepsy. Br.J.Clin.Pharmacol. 1989;27 Suppl 1:3S-11S. PubMed
  9. Loeb, C., Marinari, U. M., Benassi, E., Besio, G., Cottalasso, D., Cupello, A., Maffini, M., Mainardi, P., Pronzato, M. A., and Scotto, P. A. Phosphatidylserine increases in vivo the synaptosomal uptake of exogenous GABA in rats. Exp.Neurol. 1988;99(2):4 PubMed
  10. Melis, G. B., Paoletti, A. M., Mais, V., and Fioretti, P. Interference of dopamine infusion on gamma-amino butyric acid (GABA)-stimulated prolactin increase. J.Endocrinol.Invest 1980;3(4):445-448.
  11. Boonstra E, de Kleijn R, Colzato LS, Alkemade A, Forstmann BU, Nieuwenhuis S. Neurotransmitters as food supplements: the effects of GABA on brain and behavior. Front Psychol. 2015 Oct 6;6:1520. doi: 10.3389/fpsyg.2015.01520. eCollection 2015. PubMed
  12. de Bie TH, Witkamp RF, Balvers MG, Jongsma MA. Effects of ?-aminobutyric acid supplementation on glucose control in adults with prediabetes: A double-blind, randomized, placebo-controlled trial. Am J Clin Nutr 2023;118(3):708-719. PubMed

See these in context on the Gamma-aminobutyric Acid (gaba) monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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