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Dietary supplement

GABA 750 mg Capsules Ingredients & Drug Interactions

by Muscle Empire

GABA 750 mg Capsules label
See full label image
Softgel Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking GABA 750 mg Capsules against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

GABA 750 mg Capsules is a dietary supplement by Muscle Empire with 1 active ingredient. Its ingredients are commonly taken for anxiety and stress, sleep problems, relaxation.Based on those ingredients, 419 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are GABA (Gamma Aminobutyric Acid) powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against GABA 750 mg Capsules by Muscle Empire

Ask about any prescription or over-the-counter medication and we check it for interactions with GABA 750 mg Capsules by Muscle Empire — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of GABA 750 mg Capsules by Muscle Empire

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 30, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • “GABA (Gamma Aminobutyric Acid) powder” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.

This product contains one active ingredient: GABA (gamma-aminobutyric acid), a compound your brain naturally makes. The capsule also holds vegetable cellulose and magnesium stearate as inactive ingredients.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Gamma-aminobutyric Acid (gaba)'s own graded uses on its monograph.

Why this rating?
  • The label markets this product for: promotes muscle growth, recovery, hormone balance and sleep.
  • We looked for evidence on: Anxiety, Insomnia, Stress, Hypertension, Sleep quality, Relaxation — and 1 related terms.
  • The closest evidence on file: Gamma-aminobutyric Acid (gaba) is rated "Insufficient Reliable Evidence To Rate" for Anxiety (Natural Medicines).
  • Also on file: Gamma-aminobutyric Acid (gaba) is rated "Insufficient Reliable Evidence To Rate" for Hypertension, Insomnia, Post-traumatic stress disorder (PTSD).

The evidence for GABA isn't established in our data. It's been studied for anxiety, ADHD, athletic performance, chronic bronchitis, and cerebral palsy, but the research to date is insufficient to rate whether it actually works for any of these.

The evidence, ingredient by ingredient Gamma-aminobutyric Acid (gaba)

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

GABA is generally well tolerated when taken by mouth short-term, but we don't have good long-term safety data. The most commonly reported side effects in studies are drowsiness, upset stomach, minor throat burning, muscle weakness, and nausea.

One patient reported temporary loss of menstrual periods while taking GABA with another supplement. The safety data advises against using it during pregnancy and breastfeeding unless your doctor specifically recommends it.

Side effects, ingredient by ingredient Gamma-aminobutyric Acid (gaba)

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Gamma-aminobutyric Acid (gaba).
  • The most serious interaction on file is rated Moderate.
  • For scale: 419 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before taking this if you're on blood pressure medications (antihypertensives)—GABA may increase the drop in pressure. Also double-check if you take any CNS depressants, including benzodiazepines, opioids, sleep aids, or sedating antidepressants, since additive sleepiness is possible, though unclear how often it's a real issue.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

GABA might be worth trying if you're curious about relaxation and have no blood pressure medication or sedating drugs on board—but the evidence for its benefits isn't strong yet. If you take anything for blood pressure or sleep, or have any other medications, check them against this product first with your doctor or pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 24, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about GABA 750 mg Capsules, straight from the product label.

Brand Muscle Empire
Barcode (UPC) 798711492992
Net contents 250 Capsule(s)
Market status On market
Date entered into DSLD Mar 24, 2017
DSLD ID 71645
Product type Non-nutrient/non-botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for GABA 750 mg Capsules by Muscle Empire, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
250
UPC/BARCODE
798711492992
IngredientAmount% DV
GABA750 mg--
GABA (Gamma Aminobutyric Acid) powder0 NP--

Other ingredients: Vegetable Cellulose, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

No added fillers No flow agents No driers

Allergens: This product contains no soy, dairy & dairy byproducts, eggs, fish, shellfish, wheat, gluten, tree nuts, or sesame seeds.

General Statements

Vegicaps

Promotes muscle growth and recovery Promotes natural hormone balance Promotes healthy and deep sleep Improves relaxation

Gamma Aminobutyric Acid (GABA) is commonly referred to as the brain's most potent calming agent due to it's ability to prevent over-stimulation of the brain and initiate a healthy, deep sleep by regulating the firing within the nervous system which can commonly bring about irritability, restlessness, and anxiety. It is also suggested that GABA plays a role in the production and balance of hormones, which could be beneficial to bodybuilders and those seeing an increase in muscle growth as it may provide optimial recovery and metabolism of fat conditions.

Get big. Get hard.

FDA Statement of Identity

Dietary Supplement

Storage

Store in a cool, dry place.

Seals/Symbols

Lab tested for purity and quality

Precautions

Do not use or consume if seal is broken.

Warning: Keep out of the reach of children. Do not take this or any other supplement if under the age of 18, pregnant or nursing a baby, or if you have any known or suspected medical conditions and/or taking prescription drug(s) or OTC medication(s).

Do not take this or any other supplement if under the age of 18, pregnant or nursing a baby, or if you have any known or suspected medical conditions and/or taking prescription drug(s) or OTC medication(s).

Always consult with a qualified health physician before taking any new dietary supplement.

FDA Disclaimer Statement

These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any diseases.

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take one (1) to two (2) capsules daily or as needed.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

GABA 750 mg Capsules by Muscle Empire label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

GABA 750 mg Capsules label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in GABA 750 mg Capsules by Muscle Empire

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formSoftgel Capsule Servings per container250 Amounts shown are per serving.

GABA (Gamma Aminobutyric Acid) powder

Interacts with
419 drugs
0 NP per serving

GABA is a calming chemical messenger (neurotransmitter) that your body makes on its own, and it is sold as a supplement for stress, anxiety, and sleep...

GABA (Gamma Aminobutyric Acid) powder monograph & interactions

Other (inactive) ingredients: Vegetable Cellulose, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

GABA 750 mg Capsules by Muscle Empire Drug Interactions

Want to check YOUR meds against GABA 750 mg Capsules?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
419Drugs
172 Moderate 247 Minor

Ingredients driving the most interactions

GABA (Gamma Aminobutyric Acid) powder 419

Individual Drug Interactions

The ingredients in GABA 750 mg Capsules interact with 419 drugs. Click any drug to see the details.

1 of the 1 ingredient in GABA 750 mg Capsules interact with drugs. Each result below shows which ingredient is responsible. GABA (Gamma Aminobutyric Acid) powder

Each ingredient & the kinds of drugs it affects

For each ingredient in GABA 750 mg Capsules with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

GABA (Gamma Aminobutyric Acid) powder2 drug types · 419 drugs

Antihypertensive Drugs

Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Some clinical research shows that GABA can decrease blood pressure in patients with hypertension.

Likelihood Possible Evidence B
Cns Depressants

Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants. However, it is unclear if this concern is clinically relevant.
Endogenous GABA has well-established relaxant effects and GABA(A) receptors have an established physiological role in sleep. However, the effects of GABA supplements are unclear, as it is unknown whether exogenous GABA crosses the blood-brain barrier. Although there have been limited reports of drowsiness or tiredness with GABA supplements, these effects have not been widely reported in clinical studies. Additionally, intravenous GABA 0.1-1 mg/kg has been shown to induce anxiety in a dose-dependent manner.

Likelihood Unlikely Evidence D
GABA (Gamma Aminobutyric Acid) powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for GABA 750 mg Capsules, from the product label.

Muscle Empire

See all Muscle Empire products
Name
Supplement Partners, LLC.
Street Address
3820 W Happy Valley Rd Ste 141 - #420
City
Glendale
State
AZ
ZipCode
85310
Web Address
MUSCLEEMPIRE.COM
Pharmacist Counseling Corner

GABA 750 mg Capsules by Muscle Empire: Common Questions

Does GABA 750 mg Capsules by Muscle Empire interact with any medications?
Yes. Based on its ingredients, GABA 750 mg Capsules has a known interaction with 419 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
GABA 750 mg Capsules contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is GABA and what's it supposed to do?
GABA is a chemical your brain naturally produces that helps calm nerve activity. This supplement is marketed for relaxation and sleep, but the evidence we have isn't strong enough yet to say whether it actually works for anxiety, ADHD, athletic performance, or any other condition we've seen it studied for.
What are the most common side effects?
When taken by mouth, the most common side effects reported in studies are drowsiness, stomach upset, minor throat burning, muscle weakness, and nausea. GABA appears generally well tolerated short-term, but long-term safety hasn't been well studied.
Is GABA safe to take while pregnant or breastfeeding?
There isn't enough safety information about GABA in pregnancy and lactation. The data advises against using it while breastfeeding unless your doctor specifically recommends it. For pregnancy, talk with your doctor or pharmacist about whether it's right for you.
Can I take GABA if I'm on blood pressure medication?
GABA may lower your blood pressure further, so using it alongside blood pressure medications could increase your risk of low blood pressure (hypotension). Check with your doctor or pharmacist before combining them.
What's in the capsule besides GABA?
The inactive ingredients are vegetable cellulose and magnesium stearate—these are fillers and binders that hold the capsule together.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if GABA 750 mg Capsules is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

GABA 750 mg Capsules label
Go deeper

The Full Monographs Behind GABA 750 mg Capsules’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Gamma-aminobutyric Acid (gaba)

Interacts with 419 drugs

GABA is a calming chemical messenger (neurotransmitter) that your body makes on its own, and it is sold as a supplement for stress, anxiety, and sleep. The science behind oral GABA supplemen...

Read the full Gamma-aminobutyric Acid (gaba) monograph →
Sources

Sources & How We Checked

GABA 750 mg Capsules's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Gamma-aminobutyric Acid (gaba) 12 references
  1. Cavagnini F, Invitti C, Pinto M, et al. Effect of acute and repeated administration of gamma aminobutyric acid (GABA) on growth hormone and prolactin secretion in man. Acta Endocrinol (Copenh) 1980;93:149-54.
  2. Nurnberger JI Jr, Berrettini WH, Simmons-Alling S, et al. Intravenous GABA administration is anxiogenic in man. Psychiatry Res 1986;19:113-7. PubMed
  3. Gershman RN, Vasilenko MA, Iliushina GG, et al. [Gammalon in the rehabilitation in infantile cerebral palsy]. Pediatr.Akus.Ginekol. 1977;(6):26-7.
  4. Loeb C, Benassi E, Bo, GP, et al. Preliminary evaluation of the effect of GABA and phosphatidylserine in epileptic patients. Epilepsy Res. 1987;1:209-12 . PubMed
  5. Inoue K, Shirai T, Ochiai H, et al. Blood-pressure-lowering effect of a novel fermented milk containing gamma-aminobutyric acid (GABA) in mild hypertensives. Eur J Clin Nutr 2003;57:490-95.
  6. ELLIOTT, K. A. and JASPER, H. H. Gammaaminobutyric acid. Physiol Rev. 1959;39(2):383-406.
  7. Winsky-Sommerer, R. Role of GABAA receptors in the physiology and pharmacology of sleep. Eur.J.Neurosci. 2009;29(9):1779-1794.
  8. Meldrum, B. S. GABAergic mechanisms in the pathogenesis and treatment of epilepsy. Br.J.Clin.Pharmacol. 1989;27 Suppl 1:3S-11S. PubMed
  9. Loeb, C., Marinari, U. M., Benassi, E., Besio, G., Cottalasso, D., Cupello, A., Maffini, M., Mainardi, P., Pronzato, M. A., and Scotto, P. A. Phosphatidylserine increases in vivo the synaptosomal uptake of exogenous GABA in rats. Exp.Neurol. 1988;99(2):4 PubMed
  10. Melis, G. B., Paoletti, A. M., Mais, V., and Fioretti, P. Interference of dopamine infusion on gamma-amino butyric acid (GABA)-stimulated prolactin increase. J.Endocrinol.Invest 1980;3(4):445-448.
  11. Boonstra E, de Kleijn R, Colzato LS, Alkemade A, Forstmann BU, Nieuwenhuis S. Neurotransmitters as food supplements: the effects of GABA on brain and behavior. Front Psychol. 2015 Oct 6;6:1520. doi: 10.3389/fpsyg.2015.01520. eCollection 2015. PubMed
  12. de Bie TH, Witkamp RF, Balvers MG, Jongsma MA. Effects of ?-aminobutyric acid supplementation on glucose control in adults with prediabetes: A double-blind, randomized, placebo-controlled trial. Am J Clin Nutr 2023;118(3):708-719. PubMed

See these in context on the Gamma-aminobutyric Acid (gaba) monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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