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Dietary supplement

Ribose 750 mg Ingredients & Drug Interactions

by Swanson

Ribose 750 mg label
See full label image
Capsule Category: Fiber And Other Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Ribose 750 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Ribose 750 mg is a dietary supplement by Swanson with 1 active ingredient. Its ingredients are commonly taken for energy and fatigue, athletic performance and recovery, fibromyalgia symptoms.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bioenergy Ribose. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Ribose 750 mg by Swanson

Ask about any prescription or over-the-counter medication and we check it for interactions with Ribose 750 mg by Swanson — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Ribose 750 mg by Swanson

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Bioenergy Ribose at 750 mg per capsule. Ribose is a five-carbon sugar your cells naturally make and use for energy production.

The capsule also contains inactive ingredients — hypromellose (a thickener), rice flour, magnesium stearate (a lubricant), and silica — that help hold the capsule together and keep the powder flowing.

Does it work?

Leans against
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Leans against

The strongest graded evidence we hold for the stated purpose leans against a benefit.

Why this rating?
  • The label markets this product for: enhances cellular energy and physical performance.
  • We looked for evidence on: Athletic performance, Chronic fatigue syndrome (CFS), Fibromyalgia, Heart failure, Coronary heart disease (CHD), Muscle soreness — and 2 related terms.
  • The closest evidence on file: Ribose is rated "Possibly Ineffective" for Athletic performance (Natural Medicines).
  • Also on file: Ribose is rated "Insufficient Reliable Evidence To Rate" for Coronary heart disease (CHD), Chronic fatigue syndrome (CFS), Heart failure, Fibromyalgia, and more.

The evidence for ribose's effectiveness is mixed and often limited. For athletic performance and McArdle disease, the research suggests it's likely ineffective.

For restless legs syndrome, heart failure, muscle soreness, and recovery after bypass surgery, we don't yet have enough reliable evidence to know whether it works. If you're considering ribose for one of these uses, talk with your doctor about whether the current evidence supports a trial.

The evidence, ingredient by ingredient Ribose

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Ribose is generally well tolerated over short periods, up to about a month in the studies we have. The most common side effects from oral use are diarrhea, gastrointestinal discomfort, headache, nausea, and low blood sugar.

A few people have reported anxiety, lightheadedness, or increased appetite; lowering the dose has resolved these in some cases. Long-term safety hasn't been well studied.

During pregnancy and breastfeeding, there isn't enough safety information, so it's best to avoid it — talk with your doctor or pharmacist for personalized guidance.

Side effects, ingredient by ingredient Ribose

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Ribose.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take insulin or antidiabetes drugs, double-check this product with your doctor or pharmacist before use. Both carry a Moderate risk that ribose could lower your blood sugar further than intended.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with graded evidence leaning against its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Ribose might be worth considering if you're interested in its potential for energy or muscle recovery, but the evidence for most uses is thin or absent. If you take insulin or diabetes medication, check with your doctor or pharmacist first — the risk of low blood sugar is a real concern.

Anyone curious about ribose should discuss it with their own healthcare provider before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Ribose 750 mg, straight from the product label.

Brand Swanson
Barcode (UPC) 087614028231
Net contents 60 Veggie Capsule(s)
Market status On market
Date entered into DSLD Feb 25, 2019
DSLD ID 190975
Product type Fiber And Other Nutrients
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Ribose 750 mg by Swanson, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Veggie Capsule(s)
Maximum serving Sizes:
1 Veggie Capsule(s)
UPC/BARCODE
087614028231
IngredientAmount% DV
Bioenergy Ribose750 mg--

Other ingredients: Hypromellose, Rice Flour, Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Enhances cellular energy production and physical performance Vital for adenosine triphosphate (ATP) production Boosts antioxidant activity Science-Backed Quality Since 1969

Energy Support

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take one veggie capsule one to two times per day with water. For maximum energy level to be achieved, take up to three veggie capsules three times per day.

Brand IP Statement(s)

Bioenergy Ribose is a registered trademark of Bioenergy, Inc.

Precautions

Warning: For adults only.

Do not take this product if you are pregnant or nursing. Consult your physician before using this or any product if you are taking medication, or have a medical condition, such as hypoglycemia or diabetes.

Discontinue use if you experience gastrointestinal discomfort, nausea or headache.

Keep out of reach of children.

Do not use if seal is broken.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

General

SWU823 Rev 0 06 18 18

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Ribose 750 mg by Swanson label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Ribose 750 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Ribose 750 mg by Swanson

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Veggie Capsule(s) Dosage formCapsule Amounts shown are per serving.

Bioenergy Ribose

Interacts with
86 drugs
750 mg per serving Form: D-Ribose, Powder

Ribose (D-ribose) is a simple sugar your body makes naturally and uses to build energy molecules like ATP. Some people take it for fatigue, fibromyalg...

Bioenergy Ribose monograph & interactions

Other (inactive) ingredients: Hypromellose, Rice Flour, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Ribose 750 mg by Swanson Drug Interactions

Want to check YOUR meds against Ribose 750 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Bioenergy Ribose 86

Individual Drug Interactions

The ingredients in Ribose 750 mg interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in Ribose 750 mg interact with drugs. Each result below shows which ingredient is responsible. Bioenergy Ribose

Each ingredient & the kinds of drugs it affects

For each ingredient in Ribose 750 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Bioenergy Ribose2 drug types · 86 drugs

Antidiabetes Drugs

Theoretically, taking ribose in combination with antidiabetes drugs might increase the risk of hypoglycemia.
In clinical research, ribose decreases serum glucose levels in a dose-dependent manner.

Likelihood Probable Evidence B
Insulin

Theoretically, taking ribose with insulin could increase the hypoglycemic effect of insulin.
In clinical pharmacokinetic studies, oral administration of ribose modestly increased serum insulin levels.

Likelihood Possible Evidence B
Bioenergy Ribose full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Ribose 750 mg, from the product label.

Swanson

See all Swanson products
Name
Swanson Health Products
City
Fargo
State
ND
ZipCode
58104
Phone Number
1-800-437-4148
Web Address
swanson.com
Pharmacist Counseling Corner

Ribose 750 mg by Swanson: Common Questions

Does Ribose 750 mg by Swanson interact with any medications?
Yes. Based on its ingredients, Ribose 750 mg has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Ribose 750 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Ribose if I have diabetes or take insulin?
Not without checking first. Ribose can lower blood sugar and may increase the effect of insulin and diabetes medications, raising your risk of low blood sugar (hypoglycemia). Talk with your doctor or pharmacist — they can advise you on whether it's safe for you and whether monitoring is needed.
What are the most common side effects?
Diarrhea, gastrointestinal discomfort, headache, nausea, and low blood sugar are the most commonly reported when taken by mouth. Some people have also reported anxiety, lightheadedness, or increased appetite, though lowering the dose has helped in some cases.
Is Ribose safe to take long-term?
The studies we have show it's generally well tolerated for about a month. Long-term safety hasn't been well studied, so we don't have solid data on what happens if you take it for months or years.
Can I take Ribose while pregnant or breastfeeding?
There isn't enough safety information, so it's best to avoid it during pregnancy and breastfeeding. Talk with your doctor or pharmacist about what's right for you in your situation.
Does Ribose actually improve athletic performance?
The research suggests it's likely ineffective for that use. If you're thinking about it for sports performance or muscle recovery, the evidence doesn't currently support it — and there are better-studied options to discuss with your doctor.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Ribose 750 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Ribose 750 mg label
Go deeper

The Full Monographs Behind Ribose 750 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Ribose

Interacts with 86 drugs

Ribose (D-ribose) is a simple sugar your body makes naturally and uses to build energy molecules like ATP. Some people take it for fatigue, fibromyalgia, exercise recovery, or heart conditio...

Read the full Ribose monograph →
Sources

Sources & How We Checked

Ribose 750 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Ribose 8 references
  1. Segal S, Foley J. The metabolism of D-ribose in man. J Clin Invest 1958;37:719-35. PubMed
  2. Perlmutter NS, Wilson RA, Angello DA, et al. Ribose facilitates thallium-201 redistribution in patients with coronary artery disease. J Nucl Med 1991;32:193-200.
  3. Hegewald MG, Palac RT, Angello DA, et al. Ribose infusion accelerates thallium redistribution with early imaging compared with late 24-hour imaging without ribose. J Am Coll Cardiol 1991;18:1671-81. PubMed
  4. Pliml W, von Arnim T, Stalein A, et al. Effects of ribose on excercise-induced ischaemia in stable coronary artery disease. Lancet 1992;340:507-10.
  5. Burke ER. D-Ribose What You Need To Know. Garden City Park, NY: Avery Publishing Group 1999;1-43.
  6. Gross M, Reiter S, Zollner N. Metabolism of D-ribose administered continuously to healthy persons and to patients with myoadenylate deaminase deficiency. Klin Wochenschr 1989;67:1205-13. PubMed
  7. Teitelbaum JE, Johnson C, St Cyr J. The use of D-ribose in chronic fatigue syndrome and fibromyalgia: a pilot study. J Altern Complement Med 2006;12:857-62. PubMed
  8. Thompson J, Neutel J, Homer K, Tempero K, Shah A, Khankari R. Evaluation of D-ribose pharmacokinetics, dose proportionality, food effect, and pharmacodynamics after oral solution administration in healthy male and female subjects. J Clin Pharmacol 2014;54 PubMed

See these in context on the Ribose monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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