Rapid-Release CoQ10 200 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Rapid-Release CoQ10 200 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Rapid-Release CoQ10 200 mg is a dietary supplement by Spring Valley with 1 active ingredient. Its ingredients are commonly taken for heart health, statin-related muscle aches, migraine prevention.Based on those ingredients, 198 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Coenzyme Q10. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Rapid-Release CoQ10 200 mg by Spring Valley
Ask about any prescription or over-the-counter medication and we check it for interactions with Rapid-Release CoQ10 200 mg by Spring Valley — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Rapid-Release CoQ10 200 mg by Spring Valley
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This softgel contains one active ingredient: Coenzyme Q10 at 200 mg per capsule. CoQ10 is a compound your body makes naturally and uses for energy production in cells.
The softgel is filled with rice bran oil, gelatin, and glycerin as inactive ingredients to deliver the CoQ10.
Does it work?
Moderate evidence
CoQ10 has the strongest evidence for treating CoQ10 deficiency itself — that's rated likely effective. For other uses, the evidence is mixed: it's possibly effective for fibromyalgia, migraine headaches, congestive heart failure, and diabetic neuropathy, but the data we hold doesn't establish it as proven for these conditions.
Talk with your doctor about whether it makes sense for your situation.
How safe is it?
Well-documented data
CoQ10 is generally well tolerated by most adults when taken as directed. The most common side effects are mild gastrointestinal issues — appetite suppression, diarrhea, heartburn, nausea, vomiting — occurring in less than 1% of people.
Dividing doses above 100 mg throughout the day may help minimize these. Headache, dizziness, and insomnia have been reported occasionally; skin itching and allergic rash are rare.
There isn't enough safety data during pregnancy to know whether it's safe, so it's best to avoid it unless your doctor advises otherwise. Safety while breastfeeding hasn't been well studied — check with your doctor before use.
Meds to double-check
Moderate interaction found
Before you start, double-check with your doctor or pharmacist if you take warfarin (Coumadin) or other blood thinners — CoQ10 may reduce their effects. If you're on chemotherapy, especially alkylating agents, let your oncologist know you're considering this.
Anyone on blood pressure medication should confirm it's okay to combine, since CoQ10 may lower blood pressure further.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
CoQ10 may help if you have a documented CoQ10 deficiency or are exploring it for migraine, heart failure, or neuropathy — talk it over with your doctor first. If you take warfarin or chemotherapy, or if you're on blood pressure medication, you need to check with your doctor or pharmacist before adding this.
Pregnant or breastfeeding? Discuss it with your healthcare provider.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2018.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Rapid-Release CoQ10 200 mg, straight from the product label.
| Brand | Spring Valley |
|---|---|
| Barcode (UPC) | 681131101264 |
| Net contents | 60 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Jun 25, 2018 |
| DSLD ID | 178601 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Rapid-Release CoQ10 200 mg by Spring Valley, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 5 Calorie(s) | -- |
| Total Fat | 0.5 Gram(s) | 1% |
| Coenzyme Q10 | 200 mg | -- |
Other ingredients: Rice Bran Oil, Gelatin, Glycerin, Contains <2% of
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General
Item No. 17139 B67897W 02B 14-10172W9S 108234
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Formula
CoQ10 200 mg per softgel
Contains soy.
No gluten, yeast, wheat, milk or milk derivatives, lactose, sugar, preservatives, artificial color, artificial flavor, sodium (less than 5 mg per serving)
FDA Statement of Identity
Dietary Supplement
General Statements
Heart health Coenzyme Q10 (CoQ10) is an antioxidant and also supports energy production and cardiovascular health. CoQ10 may be beneficial for individuals taking statin medications.
Product of China
Quality Guaranteed
Precautions
Contains soy.
Warning: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.
Discontinue use and consult your doctor if any adverse reactions occur.
Keep out of reach of children.
Note: CoQ10 is not intended to serve as a replacement for statin therapy, nor should you discontinue taking any prescribed medications while supplementing with CoQ10.
For your protection, do not use if seal under cap is broken or missing.
Suggested/Recommended/Usage/Directions
Suggested Use: Adults, take one softgel daily, preferably with a meal.
Formulation
No gluten, yeast, wheat, milk or milk derivatives, lactose, sugar, preservatives, artificial color, artificial flavor, sodium (less than 5 mg per serving)
Storage
Store at room temperature 59(0)- 86(0)F (15(0)- 30(0)C). Keep bottle tightly closed.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Rapid-Release CoQ10 200 mg by Spring Valley label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Rapid-Release CoQ10 200 mg by Spring Valley
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.
Coenzyme Q10
Interacts with198 drugs
CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated...
Coenzyme Q10 monograph & interactionsOther (inactive) ingredients: Rice Bran Oil, Gelatin, Glycerin, Contains <2% of. These complete the product’s ingredient list but are not active constituents.
Rapid-Release CoQ10 200 mg by Spring Valley Drug Interactions
HelloPharmacist Interaction Report
Rapid-Release CoQ10 200 mg by Spring Valley can interact with several medication types.
The most serious concern is with blood thinners like warfarin (Coumadin): CoQ10 may have vitamin K-like effects that reduce warfarin's ability to prevent clots. Four cases of decreased warfarin effectiveness have been reported, though the effect isn't consistent across all users.
Read the full breakdown — every affected drug type, severity by severity
CoQ10 may also interfere with chemotherapy drugs, particularly alkylating agents like cyclophosphamide. Because CoQ10 is an antioxidant, it could theoretically protect tumor cells from drugs that work by creating oxidative stress — something you'll want to discuss with your oncologist if you're undergoing cancer treatment.
Minor interactions are possible with blood pressure medications. Some studies show CoQ10 can lower blood pressure on its own, so combining it with antihypertensive drugs might add up to a larger drop than intended.
Altogether, these interactions span 198 individual medications. Use the interaction checker below with your exact prescriptions before starting.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Rapid-Release CoQ10 200 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Rapid-Release CoQ10 200 mg interact with 198 drugs. Click any drug to see the details.
1 of the 1 ingredient in Rapid-Release CoQ10 200 mg interact with drugs. Each result below shows which ingredient is responsible. Coenzyme Q10
AmilorideAmilamont, Midamor
How Amiloride interacts with Rapid-Release CoQ10 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Amiloride interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Rapid-Release CoQ10 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Amiloride, Hydrochlorothiazide interactionAmlodipineNorliqva
How Amlodipine interacts with Rapid-Release CoQ10 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with Rapid-Release CoQ10 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with Rapid-Release CoQ10 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with Rapid-Release CoQ10 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Amlodipine Besylate interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with Rapid-Release CoQ10 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Amlodipine Besylate, Benazepril interactionAmlodipine, CelecoxibConsensi
How Amlodipine, Celecoxib interacts with Rapid-Release CoQ10 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Amlodipine, Celecoxib interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with Rapid-Release CoQ10 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Ammonium Chloride interactionAprocitentanTryvio
How Aprocitentan interacts with Rapid-Release CoQ10 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Aprocitentan interactionAtenololAtenix, Tenormin
How Atenolol interacts with Rapid-Release CoQ10 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Atenolol interactionAtenolol, ChlortalidoneAtenixCo, Tenoret 50, Totaretic
How Atenolol, Chlortalidone interacts with Rapid-Release CoQ10 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Atenolol, Chlortalidone interactionAtenolol, ChlorthalidoneTenoretic
How Atenolol, Chlorthalidone interacts with Rapid-Release CoQ10 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Atenolol, Chlorthalidone interactionAzilsartanEdarbi
How Azilsartan interacts with Rapid-Release CoQ10 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Azilsartan interactionAzilsartan, ChlorthalidoneEdarbyclor
How Azilsartan, Chlorthalidone interacts with Rapid-Release CoQ10 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Azilsartan, Chlorthalidone interactionBenazeprilLotensin
How Benazepril interacts with Rapid-Release CoQ10 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Benazepril interactionBenazepril, HydrochlorothiazideLotensin HCT
How Benazepril, Hydrochlorothiazide interacts with Rapid-Release CoQ10 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Benazepril, Hydrochlorothiazide interactionBendroflumethiazideAprinox, Naturetin, Neo-NaClex
How Bendroflumethiazide interacts with Rapid-Release CoQ10 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Bendroflumethiazide interactionBendroflumethiazide, NadololCorzide
How Bendroflumethiazide, Nadolol interacts with Rapid-Release CoQ10 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Bendroflumethiazide, Nadolol interactionBendroflumethiazide, Rauwolfia SerpentinaRauzide
How Bendroflumethiazide, Rauwolfia Serpentina interacts with Rapid-Release CoQ10 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Bendroflumethiazide, Rauwolfia Serpentina interactionBenzthiazideExna
How Benzthiazide interacts with Rapid-Release CoQ10 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Benzthiazide interactionBetaxololBetoptic, Kerlone
How Betaxolol interacts with Rapid-Release CoQ10 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Betaxolol interactionBisoprololZebeta
How Bisoprolol interacts with Rapid-Release CoQ10 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Bisoprolol interactionBisoprolol, HydrochlorothiazideZiac
How Bisoprolol, Hydrochlorothiazide interacts with Rapid-Release CoQ10 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Bisoprolol, Hydrochlorothiazide interactionBosentanTracleer
How Bosentan interacts with Rapid-Release CoQ10 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Bosentan interactionBumetanideBurinex
How Bumetanide interacts with Rapid-Release CoQ10 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Bumetanide interactionBumetanide (iv)Bumex
How Bumetanide (iv) interacts with Rapid-Release CoQ10 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Bumetanide (iv) interactionBumetanide (oral)Bumex
How Bumetanide (oral) interacts with Rapid-Release CoQ10 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Bumetanide (oral) interactionCandesartan CilexetilAmias, Atacand
How Candesartan Cilexetil interacts with Rapid-Release CoQ10 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Candesartan Cilexetil interactionCandesartan Cilexetil, HydrochlorothiazideAtacand HCT
How Candesartan Cilexetil, Hydrochlorothiazide interacts with Rapid-Release CoQ10 200 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Candesartan Cilexetil, Hydrochlorothiazide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Rapid-Release CoQ10 200 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Coenzyme Q10
Alkylating Agents
Coenzyme Q10 has antioxidant effects. Theoretically, this may reduce the activity of chemotherapy drugs that generate free radicals.
Theoretically, antioxidants such as coenzyme Q10 might protect tumor cells from chemotherapeutic agents that work by inducing oxidative stress, such as alkylating agents (e.g., cyclophosphamide) and radiation therapy. The clinical importance of this interaction is unknown.
Warfarin (Coumadin)
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Concomitant use of coenzyme Q10 and warfarin might reduce the anticoagulant effects of warfarin. Four cases of decreased warfarin efficacy thought to be due to coenzyme Q10 have been reported. However, there is some preliminary clinical research that suggests coenzyme Q10 might not significantly decrease the effects of warfarin in patients who have a stable INR.
Antihypertensive Drugs
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Some clinical research shows that coenzyme Q10 can significantly lower blood pressure, although other studies have shown conflicting results.
Brand information
Manufacturer and brand details for Rapid-Release CoQ10 200 mg, from the product label.
Spring Valley
See all Spring Valley products- Name
- Wal-Mart Stores, Inc.
- City
- Bentonville
- State
- AR
- ZipCode
- 72716
- Phone Number
- 1-866-251-1662
Rapid-Release CoQ10 200 mg by Spring Valley: Common Questions
Does Rapid-Release CoQ10 200 mg by Spring Valley interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does CoQ10 actually work for heart failure or migraines?
What are the side effects?
Can I take this if I'm pregnant or breastfeeding?
I take warfarin. Can I use this?
What is CoQ10 and why would I need it?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Rapid-Release CoQ10 200 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Rapid-Release CoQ10 200 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Rapid-Release CoQ10 200 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 40 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Coenzyme Q10 40 references
- Kamikawa T, Kobayashi A, Yamashita T, et al. Effects of coenzyme Q10 on exercise tolerance in chronic stable angina pectoris. Am J Cardiol 1985;56:247-51. PubMed
- Langsjoen P, Willis R, Folkers K. Treatment of essential hypertension with coenzyme Q10. Mol Aspects Med 1994;S265-72. PubMed
- Spigset O. Reduced effect of warfarin caused by ubidecarenone. Lancet 1994;334:1372-3. PubMed
- Singh RB, Niaz MA, Rastogi SS, et al. Effect of hydrosoluble coenzyme Q10 on blood pressures and insulin resistance in hypertensive patients with coronary artery disease. J Hum Hypertens 1999;13:203-8. PubMed
- Portakal O, Ozkaya O, Erden Inal M, et al. Coenzyme Q10 concentrations and antioxidant status in tissues of breast cancer patients. Clin Biochem 2000;33:279-84. PubMed
- Lund EL, Quistorff B, Spang-Thomsen M, Kristjansen PE. Effect of radiation therapy on small-cell lung cancer is reduced by ubiquinone intake. Folia Microbiol (Praha) 1998;43:505-6. PubMed
- Langsjoen PH, Langsjoen PH, Folkers K. Long-term efficacy and safety of coenzyme Q10 therapy for idiopathic dilated cardiomyopathy. Am J Cardiol 1990;65:521-3. PubMed
- Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm 2000;57:1221-7. DOI
- Landbo C, Almdal TP. [Interaction between warfarin and coenzyme Q10]. Ugeskr Laeger 1998;160:3226-7.
- Baggio E, Gandini R, Plauncher AC, et al. Italian multicenter study on the safety and efficacy of coenzyme Q10 as adjunctive therapy in heart failure. CoQ10 Drug Surveillance Investigators. Mol Aspects Med 1994;15 Suppl:S287-94. PubMed
- Burke BE, Neuenschwander R, Olson RD. Randomized, double-blind, placebo-controlled trial of coenzyme Q10 in isolated systolic hypertension. South Med J 2001;94:1112-7. PubMed
- The Huntington Study Group. A randomized, placebo-controlled trial of coenzyme Q10 and remacemide in Huntington's disease. Neurology 2001;57:397-404.
- Hodgson JM, Watts GF, Playford DA, et al. Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes. Eur J Clin Nutr 2002;56:1137-42. PubMed
- Singh RB, Neki NS, Kartikey K, et al. Effect of coenzyme Q10 on risk of atherosclerosis in patients with recent myocardial infarction. Mol Cell Biochem 2003;246:75-82. DOI
- Porterfield LM. Why did the response to warfarin change? RN 2000;63:107.
- Sandor PS, Di Clemente L, Coppola G, et al. Efficacy of coenzyme Q10 in migraine prophylaxis: A randomized controlled trial. Neurology 2005;64:713-5. PubMed
- Engelsen J, Nielsen JD, Winther K. Effect of coenzyme Q10 and Ginkgo biloba on warfarin dosage in stable, long-term warfarin treated outpatients. A randomised, double blind, placebo-crossover trial. Thromb Haemost 2002;87:1075-6. DOI
- Berman M, Erman A, Ben-Gal T, et al. Coenzyme Q10 in patients with end-stage heart failure awaiting cardiac transplantation: a randomized, placebo-controlled study. Clin Cardiol 2004;27:295–9. PubMed
- Storch A, Jost WH, Vieregge P, et al. Randomized, double-blind, placebo-controlled trial on symptomatic effects of coenzyme Q10 in Parkinson disease. Arch Neurol 2007;64:938-44. DOI
- Digiesi V, Cantini F, Oradei A, et al. Coenzyme Q10 in essential hypertension. Mol Aspects Med 1994;15 Suppl:s257-63. PubMed
- Yamagami T, Takagi M, Akagami H, et al. Effect of coenzyme Q10 on essential hypertension, a double blind controlled study. In: Folkers KA, Yamamura Y, eds. Biomedical and Clinical Aspects of Coenzyme Q, Vol. 5. Amsterdam: Elsevier Science Publications, 19
- Ho MJ, Bellusci A, Wright JM. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension (review). Cochrane Database Syst Rev 2009;(4):CD007435. PubMed
- Rosenfeldt, F. L., Haas, S. J., Krum, H., Hadj, A., Ng, K., Leong, J. Y., and Watts, G. F. Coenzyme Q10 in the treatment of hypertension: a meta-analysis of the clinical trials. J Hum.Hypertens. 2007;21(4):297-306. PubMed
- Stamelou, M., Reuss, A., Pilatus, U., Magerkurth, J., Niklowitz, P., Eggert, K. M., Krisp, A., Menke, T., Schade-Brittinger, C., Oertel, W. H., and Hoglinger, G. U. Short-term effects of coenzyme Q10 in progressive supranuclear palsy: a randomized, place DOI
- Keogh A, Fenton S, Leslie C, et al. Randomised double-blind, placebo-controlled trial of coenzyme Q, therapy in class II and III systolic heart failure. Heart Lung Circ. 2003;12:135-41.
- Gane, E. J., Weilert, F., Orr, D. W., Keogh, G. F., Gibson, M., Lockhart, M. M., Frampton, C. M., Taylor, K. M., Smith, R. A., and Murphy, M. P. The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C
- Lynch, D. R., Perlman, S. L., and Meier, T. A phase 3, double-blind, placebo-controlled trial of idebenone in friedreich ataxia. Arch Neurol. 2010;67(8):941-947. PubMed
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