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Dietary supplement

Raspberry Ketone Ingredients & Drug Interactions

by AFI America's Finest

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Raspberry Ketone is a dietary supplement by AFI America's Finest with 1 active ingredient. Its ingredients are commonly taken for weight loss, fat burning, boosting metabolism.Based on those ingredients, 174 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Raspberry Ketone. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Raspberry Ketone by AFI America's Finest

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This supplement contains one active ingredient: raspberry ketone, a compound extracted from red raspberries. Raspberry ketone is the substance that gives raspberries their aroma and is also used in food flavoring.

The capsule also contains three inactive ingredients — microcrystalline cellulose, magnesium stearate, and silicon dioxide — which serve as a filler, lubricant, and anti-caking agent.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Raspberry Ketone's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: fat burning and weight loss.
  • We looked for evidence on: Obesity, metabolic rate, appetite regulation.
  • The closest evidence on file: Raspberry Ketone is rated "Insufficient Reliable Evidence To Rate" for Obesity (Natural Medicines).

The evidence for raspberry ketone is limited. For both alopecia areata (a condition causing hair loss) and obesity, the data we hold shows insufficient reliable evidence to establish whether it works.

This doesn't mean it doesn't work — it means human studies haven't yet provided solid proof of benefit at supplement doses.

The evidence, ingredient by ingredient Raspberry Ketone

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Raspberry ketone is used safely in food, but safety data for high supplement doses in humans is very limited. Because its structure resembles a stimulant drug, stimulant-related side effects are possible, though not well studied.

Case reports describe heart palpitations, rapid heartbeat, elevated blood pressure, and in rare instances, serious heart rhythm problems. A few people have also reported sweating, diarrhea, and shakiness.

During pregnancy, there isn't enough safety information, so concentrated supplements should be avoided. The same applies to breastfeeding — safety data is insufficient, so supplemental use is not advised.

Talk with your doctor or pharmacist about whether this product is right for your situation.

Side effects, ingredient by ingredient Raspberry Ketone

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Raspberry Ketone.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 174 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before taking this product if you use stimulant drugs (the Moderate risk of heart effects is the main concern here) or warfarin. Altogether, these interactions span 174 individual medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Raspberry Ketone might appeal to those interested in weight management or hair health, but evidence for either use is not yet established. The bigger concern is if you take a stimulant medication or warfarin — the documented interactions could affect how these drugs work and carry real risks.

Before you start, check your medications with your doctor or pharmacist, especially if you have heart conditions, take stimulants, or use blood thinners.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Raspberry Ketone, straight from the product label.

Brand AFI America's Finest
Barcode (UPC) 767382033513
Net contents 30 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Jan 23, 2015
DSLD ID 41328
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Raspberry Ketone by AFI America's Finest, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
30
UPC/BARCODE
767382033513
IngredientAmount% DV
Raspberry Ketone250 mg--

Other ingredients: Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Storage

Store in a cool, dry place.

Precautions

This bottle is sealed with a printed outer film and an inner freshness seal. Do not use if either seal is broken or missing.

Keep all supplements out of the reach of children.

Consult a health care professional before using if taking prescription medications, or if pregnant or nursing.

General Statements

Materials Certified by Sabinsa

Powerful Fat Burner*

Raspberry Ketone is a powerful fat burning substance, added with a healthy lifestyle incorporating exercise may lead to healthy weight management.

America's Finest, Inc. herbal formulas blend the rich herbal wisdom of ancient cultures with the finest in current scientific research and manufacturing methods. Traditional healthcare systems, such as Ayurveda which means "the Science of Life," are being validated by medical and nutritional research. With America's Finest, Inc. modern healthcare meets the "Science of Life for the JOY of Living"

Brand IP Statement(s)

(C) 2011

Seals/Symbols

AFI

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: Take one capsule daily.

FDA Disclaimer Statement

*These statements have not been evaluated by the F.D.A. This product is not intended to diagnose, treat, cure, prevent or mitigate any disease.

See for yourself

Raspberry Ketone by AFI America's Finest label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Raspberry Ketone by AFI America's Finest

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Raspberry Ketone

Interacts with
174 drugs
250 mg per serving

Raspberry ketone is a natural aroma compound found in red raspberries that is heavily marketed for weight loss, but there is no good human evidence th...

Raspberry Ketone monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Raspberry Ketone by AFI America's Finest Drug Interactions

Want to check YOUR meds against Raspberry Ketone?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
174Drugs
174 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Raspberry Ketone with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Raspberry Ketone2 drug types · 174 drugs

Stimulant Drugs

Theoretically, raspberry ketone might increase the risk of adverse cardiovascular effects with stimulant drugs.
Structurally, raspberry ketone resembles synephrine, a known stimulant agent. Heart palpitations, elevated blood pressure, coronary vasospasm, pulseless electrical activity arrest, and resistant polymorphic ventricular tachycardia have been reported in patients taking raspberry ketone.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, raspberry ketone might increase warfarin dose requirements.
In one case report, a patient taking warfarin 55 mg per week had a decrease in INR over a period of one month while taking raspberry ketone 250 mg daily. A warfarin dose increase to 70 mg per week was necessary to maintain a therapeutic INR while taking raspberry ketone. The mechanism for this potential interaction is not known.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Raspberry Ketone, from the product label.

AFI America's Finest

See all AFI America's Finest products
Name
America's Finest, Inc.
City
East Windsor
State
NJ
ZipCode
08520
Phone Number
800-350-3305
Web Address
www.afisupplements.com
Pharmacist Counseling Corner

Raspberry Ketone by AFI America's Finest: Common Questions

Does Raspberry Ketone by AFI America's Finest interact with any medications?
Yes. Based on its ingredients, Raspberry Ketone has a known interaction with 174 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Raspberry Ketone contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is raspberry ketone and where does it come from?
Raspberry ketone is a natural compound found in red raspberries that gives them their smell. It's also made synthetically and used as a food flavoring. This supplement is a concentrated dose of that single compound.
Does raspberry ketone actually help with weight loss?
The evidence isn't established yet. Our data shows insufficient reliable evidence to say whether it works for obesity, so we can't confirm a benefit based on current studies.
Is it safe to take during pregnancy or breastfeeding?
No — there isn't enough safety information. You should avoid concentrated raspberry ketone supplements during pregnancy and breastfeeding. Talk with your doctor or pharmacist about what's safe for you.
What are the possible side effects?
Because raspberry ketone resembles a stimulant, stimulant-like side effects are possible, though they aren't well studied. Case reports mention heart palpitations, rapid heartbeat, elevated blood pressure, and in rare instances, serious heart rhythm problems. Some people have reported sweating, diarrhea, and shakiness.
Can I take this if I'm on a blood thinner like warfarin?
Not without talking to your doctor first. Raspberry ketone may reduce how well warfarin works by speeding up how your body clears it, which means your blood clot risk could go up. Your doctor might need to adjust your warfarin dose if you take both.
What's in the capsule besides the active ingredient?
The capsule contains microcrystalline cellulose (a filler), magnesium stearate (a lubricant), and silicon dioxide (an anti-caking agent). These are common inactive ingredients in supplements.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Raspberry Ketone is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Raspberry Ketone label
Sources

Sources & How We Checked

Raspberry Ketone's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Raspberry Ketone 4 references
  1. Adverse Event Report. Raspberry Ketone. Natural MedWatch, April 27, 2012.
  2. Adverse Event Report. Raspberry Ketone. Natural MedWatch, September 18, 2011.
  3. Ansari SA, Patel F, Ashouri D, Dhaliwal JSS, Desai A. Resistant Polymorphic Ventricular Tachycardia in a Patient Taking Raspberry Ketones Weight Loss Supplement. Cureus 2022;14(12):e33089. PubMed
  4. Khattar A, Beeton I. Coronary vasospasm and raspberry ketones weight-loss supplement: Is there a connection? Anatol J Cardiol. 2020;24(3):205-208.

See these in context on the Raspberry Ketone monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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