Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Raspberry Ketone Liquid Diet Drops Ingredients & Drug Interactions

by Fat Drop

Raspberry Ketone Liquid Diet Drops label
See full label image
Liquid Category: Botanical With Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Raspberry Ketone Liquid Diet Drops against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Raspberry Ketone Liquid Diet Drops is a dietary supplement by Fat Drop with 2 active ingredients. Its ingredients are commonly taken for weight loss, fat burning, boosting metabolism.Based on those ingredients, 336 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Chromium, Raspberry Ketone. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Raspberry Ketone Liquid Diet Drops by Fat Drop

Ask about any prescription or over-the-counter medication and we check it for interactions with Raspberry Ketone Liquid Diet Drops by Fat Drop — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Raspberry Ketone Liquid Diet Drops by Fat Drop

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This liquid diet drop contains 2 active ingredients. Raspberry ketone is included for weight management, though the evidence supporting it is insufficient.

Chromium is added to support blood sugar control — it's rated possibly effective for diabetes and likely effective for chromium deficiency. The product also contains several inactive ingredients (fillers and flavorings): vegetable glycerin, propylene glycol, natural and artificial flavors, citric acid, sucralose, food coloring, and preservatives.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: help you lose weight quickly.
  • We looked for evidence on: Obesity, Binge eating disorder, Metabolic syndrome, weight management, fat loss, appetite suppression.
  • The closest evidence on file: Chromium is rated "Insufficient Reliable Evidence To Rate" for Obesity (Natural Medicines).
  • Also on file: Chromium is rated "Insufficient Reliable Evidence To Rate" for Metabolic syndrome, Binge eating disorder.
  • Also on file: Raspberry Ketone is rated "Insufficient Reliable Evidence To Rate" for Obesity.

Chromium in this product is likely effective for chromium deficiency and possibly effective for diabetes, meaning some research supports its use in those settings. Raspberry ketone, however, lacks sufficient reliable evidence — we don't have solid data showing it works for weight loss or hair loss.

If blood sugar control or chromium deficiency is your goal, chromium may help; if you're counting on raspberry ketone for weight management, the science doesn't back that claim yet.

The evidence, ingredient by ingredient Raspberry Ketone Chromium

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Raspberry ketone is used safely in foods but human safety data at high supplement doses is very limited. The most concerning side effects reported are cardiovascular: heart palpitations, fast heartbeat, elevated blood pressure, and in rare cases, serious arrhythmias.

Sweating, diarrhea, and shakiness have also been reported. Chromium is generally well tolerated at typical doses, though high or long-term use may carry risks.

Common minor effects include stomach upset, headache, insomnia, mood changes, and skin reactions. Rare serious effects (kidney and liver damage, blood disorders) have been reported with very high doses over months.

During pregnancy, small amounts of chromium from diet or prenatal vitamins are considered acceptable, but extra supplement doses should be avoided unless your doctor recommends it. Raspberry ketone has insufficient safety information — the facts advise against it in pregnancy.

Breastfeeding: avoid raspberry ketone due to lack of safety data; chromium has limited data on higher doses, so check with your doctor or pharmacist before using while nursing.

Side effects, ingredient by ingredient Raspberry Ketone Chromium

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Chromium, Raspberry Ketone.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 336 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you're on stimulant drugs (major cardiovascular risk), warfarin or other blood thinners, diabetes medications or insulin, levothyroxine (thyroid replacement), NSAIDs, or aspirin. Stimulants and blood thinners carry the highest-severity concerns; blood sugar and thyroid medications also need review.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product combines two ingredients with real drug interactions and limited proven benefits. If you're taking a stimulant, blood thinner, diabetes medication, insulin, or thyroid replacement, you'll want to discuss this with your doctor or pharmacist before starting — some of these combinations could affect how your medications work or raise safety concerns.

Even if you're on nothing else, the cardiovascular side effects reported with raspberry ketone deserve a conversation with your healthcare provider, especially if you have heart rhythm issues or high blood pressure.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2014.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Raspberry Ketone Liquid Diet Drops, straight from the product label.

Brand Fat Drop
Barcode (UPC) 746888778807
Net contents 2 fl. Oz.; 60 mL
Market status On market
Date entered into DSLD Mar 25, 2014
DSLD ID 31517
Product type Botanical With Nutrients
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Raspberry Ketone Liquid Diet Drops by Fat Drop, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 mL
Maximum serving Sizes:
2 mL
Servings per container
30
UPC/BARCODE
746888778807
IngredientAmount% DV
Raspberry Ketone125 mg--
Chromium10 mcg8%

Other ingredients: Vegetable Glycerin, purified Water, Natural and Artificial flavors, Propylene Glycol, polysorbate 20, Citric Acid, Sucralose, FD&C Red #40, Acesulfame Potassium, potassium sorbate, Sodium Hexametaphosphate, modified acacia gum, sodium benzoate, Xanthan Gum

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

NO VARNISH

www.MyFatDrop.com

BREAKDOWN COMPARISON BY FORM ~ REGULAR TABLETS ~ SOFTGELS ~LIQUIDS {GRAPH}

NEW!

~ Promotes Body Fat Reduction* ~ Supports Increased Metabolism*

Delicious Raspberry Flavor

30 Servings

LOT/EXP:

BURN FAT FAST!* Raspberry Ketone helps to Block Fat – by encouraging the body to use fat instead of storing it, which can help you lose weight.* In order to get enough ketone to burn excess fat, you would need to eat 90 lbs of raspberries! Forget that!

This supplement should be taken in conjunction with a healthy diet and regular exercise program. Results may vary.

10X Faster than regular tablets

Drop, Mix and Lose Weight!

FDA Disclaimer Statement

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat,cure or prevent any disease.

Brand IP Statement(s)

Fat Drop(R) is a line of fast-acting liquid concentrates featuring the most popular diet ingredients and formulations.

Unlike tablets and softgels which must first break down in the stomach, Fat Drop(R) Liquid Diet Drops go right to work. So to quickly jump start your weight loss, reach for Fat Drop(R).

Taking just 2 dropperfuls of Fat Drop(R) Raspberry Ketone Liquid Diet Drops with meals is enough to get your body burning fat the way you want it to!

Suggested/Recommended/Usage/Directions

Simply mix with water to create a great-tasting drink that will help you lose weight.

Directions: Shake well. Adults, mix 2 dropperfuls (2 mL) with 6  oz of cold water and drink 30 minutes prior to a meal twice a day.

Precautions

Warning: Not intended for use by persons under 18.

Consult doctor before use if you have a medical condition or if you are taking any prescription medications and/or over-the-counter drugs. Do not use if pregnant or nursing.

Seals/Symbols

HNS

FDA Statement of Identity

DIETARY SUPPLEMENT

General

B-7880-1

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Raspberry Ketone Liquid Diet Drops by Fat Drop label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Raspberry Ketone Liquid Diet Drops label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Raspberry Ketone Liquid Diet Drops by Fat Drop

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 mL Dosage formLiquid Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Raspberry Ketone

Interacts with
174 drugs
125 mg per serving

Raspberry ketone is a natural aroma compound found in red raspberries that is heavily marketed for weight loss, but there is no good human evidence th...

Raspberry Ketone monograph & interactions

Chromium

Interacts with
178 drugs
10 mcg per serving Form: Chromium Chloride

Chromium is an essential trace mineral involved in how the body handles sugar and fat. Some studies suggest it may modestly help blood sugar control i...

Chromium monograph & interactions

Other (inactive) ingredients: Vegetable Glycerin, Purified Water, Natural and Artificial flavors, Propylene Glycol, Polysorbate 20, Citric Acid, Sucralose, FD&C Red #40, Acesulfame Potassium, Potassium sorbate, Sodium Hexametaphosphate, Modified acacia gum, Sodium benzoate, Xanthan Gum. These complete the product’s ingredient list but are not active constituents.

Interaction report

Raspberry Ketone Liquid Diet Drops by Fat Drop Drug Interactions

Want to check YOUR meds against Raspberry Ketone Liquid Diet Drops?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
336Drugs
263 Moderate 73 Minor

Ingredients driving the most interactions

Chromium 178
Raspberry Ketone 174

Individual Drug Interactions

The ingredients in Raspberry Ketone Liquid Diet Drops interact with 336 drugs. Click any drug to see the details.

2 of the 2 ingredients in Raspberry Ketone Liquid Diet Drops interact with drugs. Each result below shows which ingredient is responsible. Chromium Raspberry Ketone

Each ingredient & the kinds of drugs it affects

For each ingredient in Raspberry Ketone Liquid Diet Drops with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Chromium5 drug types · 178 drugs

Antidiabetes Drugs

Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Some research shows that taking chromium might lower blood glucose levels, especially in patients with poorly controlled type 2 diabetes.

Likelihood Possible Evidence A
Insulin

Theoretically, concomitant use of chromium and insulin might increase the risk of hypoglycemia.
In clinical research, chromium has been shown to increase insulin sensitivity,

Likelihood Possible Evidence B
Levothyroxine (Synthroid, Others)

Chromium might bind levothyroxine in the intestinal tract and decrease levothyroxine absorption.
Clinical research in healthy volunteers shows that taking chromium picolinate 1000 mcg with levothyroxine 1 mg decreases serum levels of levothyroxine by 17% when compared to taking levothyroxine alone. Advise patients to take levothyroxine at least 30 minutes before or 3-4 hours after taking chromium.

Likelihood Probable Evidence B
Aspirin

Theoretically, aspirin might increase chromium absorption.
Animal research suggests that aspirin may increase chromium absorption and chromium levels in the blood.

Likelihood Possible Evidence D
Nonsteroidal Anti-Inflammatory Drugs (Nsaids)

NSAIDs might increase chromium levels in the body.
Drugs that are prostaglandin inhibitors, such as NSAIDs, seem to increase chromium absorption and retention.

Likelihood Possible Evidence D
Chromium full monograph & interactions

Raspberry Ketone2 drug types · 174 drugs

Stimulant Drugs

Theoretically, raspberry ketone might increase the risk of adverse cardiovascular effects with stimulant drugs.
Structurally, raspberry ketone resembles synephrine, a known stimulant agent. Heart palpitations, elevated blood pressure, coronary vasospasm, pulseless electrical activity arrest, and resistant polymorphic ventricular tachycardia have been reported in patients taking raspberry ketone.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, raspberry ketone might increase warfarin dose requirements.
In one case report, a patient taking warfarin 55 mg per week had a decrease in INR over a period of one month while taking raspberry ketone 250 mg daily. A warfarin dose increase to 70 mg per week was necessary to maintain a therapeutic INR while taking raspberry ketone. The mechanism for this potential interaction is not known.

Likelihood Possible Evidence D
Raspberry Ketone full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Raspberry Ketone Liquid Diet Drops, from the product label.

Fat Drop

See all Fat Drop products
Name
HEALTHY NATURAL SYSTEMS
Street Address
3750 Investment Lane, Suite 2
City
West Palm Beach
State
FL
ZipCode
33404
Web Address
www.MyFatDrop.com
Pharmacist Counseling Corner

Raspberry Ketone Liquid Diet Drops by Fat Drop: Common Questions

Does Raspberry Ketone Liquid Diet Drops by Fat Drop interact with any medications?
Yes. Based on its ingredients, Raspberry Ketone Liquid Diet Drops has a known interaction with 336 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Raspberry Ketone Liquid Diet Drops contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does raspberry ketone actually help with weight loss?
The evidence isn't there yet — we have insufficient reliable data to say whether it works. It's marketed for weight management, but human studies haven't proven the benefit clearly enough.
Can I take this if I'm on levothyroxine for my thyroid?
The chromium in this product can lower how much levothyroxine your body absorbs by around 17%, which could make your thyroid medication less effective. Talk to your doctor or pharmacist before taking this together — they may recommend timing the doses apart or adjusting your thyroid dose.
What are the most worrying side effects?
Raspberry ketone may cause heart palpitations, fast heartbeat, and high blood pressure — even serious arrhythmias in rare cases. These happen because it resembles a stimulant compound. If you have any history of heart rhythm problems or high blood pressure, mention that to your doctor before trying this.
Is chromium safe if I have diabetes and take insulin or diabetes pills?
Chromium may lower blood sugar on its own and could add to the effect of your medication, increasing the risk of low blood sugar. Check with your doctor or pharmacist first — they can monitor your blood sugar and adjust your diabetes medication if needed.
Can I take this while pregnant or breastfeeding?
Raspberry ketone: avoid — there isn't enough safety information. Chromium: small amounts from food or prenatal vitamins are okay, but extra supplement doses should be avoided unless your doctor says otherwise. Talk to your doctor or pharmacist for personalized advice for your pregnancy or breastfeeding situation.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Raspberry Ketone Liquid Diet Drops is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Raspberry Ketone Liquid Diet Drops label
Go deeper

The Full Monographs Behind Raspberry Ketone Liquid Diet Drops’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Raspberry Ketone

Interacts with 174 drugs

Raspberry ketone is a natural aroma compound found in red raspberries that is heavily marketed for weight loss, but there is no good human evidence that it helps people lose weight. Most cla...

Read the full Raspberry Ketone monograph → Herb & supplement monograph

Chromium

Interacts with 178 drugs

Chromium is an essential trace mineral involved in how the body handles sugar and fat. Some studies suggest it may modestly help blood sugar control in certain people with type 2 diabetes, b...

Read the full Chromium monograph →
Sources

Sources & How We Checked

Raspberry Ketone Liquid Diet Drops's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 57 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Raspberry Ketone 4 references
  1. Adverse Event Report. Raspberry Ketone. Natural MedWatch, April 27, 2012.
  2. Adverse Event Report. Raspberry Ketone. Natural MedWatch, September 18, 2011.
  3. Ansari SA, Patel F, Ashouri D, Dhaliwal JSS, Desai A. Resistant Polymorphic Ventricular Tachycardia in a Patient Taking Raspberry Ketones Weight Loss Supplement. Cureus 2022;14(12):e33089. PubMed
  4. Khattar A, Beeton I. Coronary vasospasm and raspberry ketones weight-loss supplement: Is there a connection? Anatol J Cardiol. 2020;24(3):205-208.

See these in context on the Raspberry Ketone monograph →

Chromium 53 references
  1. Cerulli J, Grabe DW, Gauthier I, et al. Chromium picolinate toxicity. Ann Pharmacother 1998;32:428-31. PubMed
  2. Urberg M, Zemel MB. Evidence for synergism between chromium and nicotinic acid in the control of glucose tolerance in elderly humans. Metabolism 1987;36:896-9. PubMed
  3. Mohamedshah FY, Moser-Veillon PB, Yamini S, et al. Distribution of a stable isotope of chromium (53Cr) in serum, urine, and breast milk in lactating women. Am J Clin Nutr 1998;67:1250-5. PubMed
  4. Wasser WG, Feldman NS, D'Agati VD. Chronic renal failure after ingestion of over-the-counter chromium picolinate. [letter]. Ann Intern Med 1997;126:410. PubMed
  5. Mertz W. Interaction of chromium with insulin: a progress report. Nutr Rev 1998;56:174-7. PubMed
  6. Anderson RA. Chromium, glucose intolerance and diabetes. J Am Coll Nutr 1998;17:548-55. PubMed
  7. McLeod MN, Gaynes BN, Golden RN. Chromium potentiation of antidepressant pharmacotherapy for dysthymic disorder in 5 patients. J Clin Psych 1999;60:237-40. PubMed
  8. Fowler JF Jr. Systemic contact dermatitis caused by oral chromium picolinate. Cutis 2000;65:116. DOI
  9. Trent LK, Thieding-Cancel D. Effects of chromium picolinate on body composition. J Sports Med Phys Fitness 1995;35:273-80.
  10. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  11. Rabinovitz H, Friedensohn A, Leibovitz A, et al. Effect of chromium supplementation on blood glucose and lipid levels in type 2 diabetes mellitus elderly patients. Int J Vitam Nutr Res 2004;74:178-82. PubMed
  12. Lanca S, Alves A, Vieira AI, et al. Chromium-induced toxic hepatitis. Eur J Intern Med 2002;13:518-20. PubMed
  13. Kockler DR, McCarthy MW, Lawson CL. Seizure activity and unresponsiveness after hydroxycut ingestion. Pharmacotherapy 2001;21:647-51.. PubMed
  14. Davidson JR, Abraham K, Connor KM, McLeod MN. Effectiveness of chromium in atypical depression: a placebo-controlled trial. Biol Psychiatry 2003;53:261-4.. PubMed
  15. Food Standards Agency. Medicines and Healthcare products Regulatory Agency (MHRA). Expert Group on Vitamins and Minerals. Available at: http://cot.food.gov.uk/sites/default/files/vitmin2003.pdf.
  16. Mouser JF, Hak EB, Helms RA, et al. Chromium and zinc concentrations in pediatric patients receiving long-term parenteral nutrition. Am J Health Syst Pharm 1999;56:1950-6. PubMed
  17. Stevens T, Qadri A, Zein NN. Two patients with acute liver injury associated with use of the herbal weight-loss supplement hydroxycut. Ann Intern Med 2005;142:477-8. PubMed
  18. Wani S, Weskamp C, Marple J, Spry L. Acute tubular necrosis associated with chromium picolinate-containing dietary supplement. Ann Pharmacother 2006;40:563-6. PubMed
  19. Kleefstra N, Houweling ST, Jansman FG, et al. Chromium treatment has no effect in patients with poorly controlled, insulin-treated type 2 diabetes in an obese Western population: a randomized, double-blind, placebo-controlled trial. Diabetes Care 2006;29: PubMed
  20. Martin J, Wang ZQ, Zhang XH, et al. Chromium picolinate supplementation attenuates body weight gain and increases insulin sensitivity in subjects with type 2 diabetes. Diabetes Care 2006;29:1826-32. PubMed
  21. Singer GM, Geohas J. The effect of chromium picolinate and biotin supplementation on glycemic control in poorly controlled patients with type 2 diabetes mellitus: a placebo-controlled, double-blinded, randomized trial. Diabetes Technol Ther 2006;8:636-43. PubMed
  22. John-Kalarickal J, Pearlman G, Carlson HE. New medications which decrease levothyroxine absorption. Thyroid 2007;17:763-5. PubMed
  23. Yazaki Y, Faridi Z, Ma Y, et al. A pilot study of chromium picolinate for weight loss. J Altern Complement Med 2010;16:291-9. PubMed
  24. Davis ML, Seaborn CD, and Stoecker BJ. Effects of over-the-counter drugs on chromium retention and urinary excretion in rats. Nutrition Research 1995;15(2):201-210.
  25. Young P, Turiansky G, Bonner M, and et al. Acute generalized exanthematous pustulosis induced by chromium picolinate. J.Am Acad.Dermatol. 1999;41(5 Pt 2):820-823. PubMed
  26. Gibb, H. J., Lees, P. S., Pinsky, P. F., and Rooney, B. C. Lung cancer among workers in chromium chemical production. Am J Ind.Med 2000;38(2):115-126. DOI
  27. Gibb, H. J., Lees, P. S., Pinsky, P. F., and Rooney, B. C. Clinical findings of irritation among chromium chemical production workers. Am J Ind.Med 2000;38(2):127-131. PubMed
  28. Pittler, M. H. and Ernst, E. Dietary supplements for body-weight reduction: a systematic review. Am.J.Clin Nutr. 2004;79(4):529-536. PubMed
  29. Pei, D., Hsieh, C. H., Hung, Y. J., Li, J. C., Lee, C. H., and Kuo, S. W. The influence of chromium chloride-containing milk to glycemic control of patients with type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled trial. Metabolism 2 PubMed
  30. Hisatomi, K., Ishii, H., Hashiguchi, K., Seki, M., Ide, M., Sugiyama, K., Ishimoto, H., Nakayama, S., Mukae, H., and Kohno, S. Interstitial pneumonia caused by inhalation of fumes of nickel and chrome. Respirology. 2006;11(6):814-817. PubMed
  31. Kleefstra, N., Houweling, S. T., Bakker, S. J., Verhoeven, S., Gans, R. O., Meyboom-de Jong, B., and Bilo, H. J. Chromium treatment has no effect in patients with type 2 diabetes in a Western population: a randomized, double-blind, placebo-controlled tri DOI
  32. Parsons, A., Ingram, J., Inglis, J., Aveyard, P., Johnstone, E., Brown, K., Franklin, M., and Bermudez, I. A proof of concept randomised placebo controlled factorial trial to examine the efficacy of St John's wort for smoking cessation and chromium to pr
  33. Bagdon RE and Hazen RE. Skin permeation and cutaneous hypersensitivity as a basis for making risk assessments of chromium as a soil contaminant. Environ.Health Perspect. 1991;92:111-119. PubMed
  34. Bharmal, S. V., Moyes, V., Ahmed, S., and Grossman, A. Hypoglycaemia: possible mediation by chromium salt medication. Hormones.(Athens.) 2010;9(2):181-183. PubMed
  35. Krol, E., Krejpcio, Z., Byks, H., Bogdanski, P., and Pupek-Musialik, D. Effects of chromium brewer's yeast supplementation on body mass, blood carbohydrates, and lipids and minerals in type 2 diabetic patients. Biol.Trace Elem.Res. 2011;143(2):726-737.
  36. Unisa, S., Jagannath, P., Dhir, V., Khandelwal, C., Sarangi, L., and Roy, T. K. Population-based study to estimate prevalence and determine risk factors of gallbladder diseases in the rural Gangetic basin of North India. HPB (Oxford) 2011;13(2):117-125. PubMed
  37. Noda, S., Asano, Y., and Sato, S. Lichen planus in a patient with long-term exposure to chrome. Eur.J.Dermatol. 2011;21(3):417-418. PubMed
  38. Xiang, J., Sun, Z., and Huan, J. N. Intensive chromic acid burns and acute chromium poisoning with acute renal failure. Chin Med.J.(Engl.) 7-5-2011;124(13):2071-2073.
  39. Chhabra, D., Oda, K., Jagannath, P., Utsunomiya, H., Takekoshi, S., and Nimura, Y. Chronic heavy metal exposure and gallbladder cancer risk in India, a comparative study with Japan. Asian Pac.J.Cancer Prev. 2012;13(1):187-190. PubMed
  40. Huszonek, J. Over-the-counter chromium picolinate. Am J Psychiatry 1993;150(10):1560-1561. PubMed
  41. Bunner S and McGinnis R. Chromium-induced hypoglycemia. Psychosomatics 1998;39(3):298-299. PubMed
  42. Martin, W. R. and Fuller, R. E. Suspected chromium picolinate-induced rhabdomyolysis. Pharmacotherapy 1998;18(4):860-862. DOI
  43. Proctor, D. M., Fredrick, M. M., Scott, P. K., Paustenbach, D. J., and Finley, B. L. The prevalence of chromium allergy in the United States and its implications for setting soil cleanup: a cost-effectiveness case study. Regul.Toxicol Pharmacol 1998;28(1 PubMed
  44. De Marchi S, Cecchin E, De Marchi SU. Systemic allergic dermatitis resulting from oral administration of chromium with a food supplement. Contact Dermatitis 2014;70(2):123-5. PubMed
  45. Hedberg YS, Gumulka M, Lind ML, Matura M, Lidén C. Severe occupational chromium allergy despite cement legislation. Contact Dermatitis. 2014;70(5):321-3. PubMed
  46. Thyssen JP, Jellesen MS, Møller P, Menné T, Johansen JD. Allergic chromium dermatitis from wearing 'chromium-free' footwear. Contact Dermatitis 2014;70(3):185-7. PubMed
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See these in context on the Chromium monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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