Red Wine Extract 500 mg Ingredients & Drug Interactions
by Swanson
What is this page for?
First and foremost: checking Red Wine Extract 500 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Red Wine Extract 500 mg is a dietary supplement by Swanson with 1 active ingredient. Its ingredients are commonly taken for social and relaxation use, heart health (popular belief), antioxidant intake.Based on those ingredients, 926 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Red Wine Fruit Extract, Fresh. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Red Wine Extract 500 mg by Swanson
Ask about any prescription or over-the-counter medication and we check it for interactions with Red Wine Extract 500 mg by Swanson — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Red Wine Extract 500 mg by Swanson
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: red wine fruit extract, which delivers the compounds found in red grapes and wine. The capsule also contains several inactive ingredients — gelatin, maltodextrin, rice bran, silica, and magnesium stearate — that are fillers and binders.
Does it work?
Moderate evidence
Red wine extract is possibly effective for several conditions: it may help with Helicobacter pylori (a stomach bacteria), osteopenia (lower bone density), cardiovascular disease (heart and blood vessel health), and diabetes. That said, the evidence backing these uses isn't conclusive, and we'd recommend talking with your doctor about whether it makes sense for your specific situation.
How safe is it?
Well-documented data
This product contains alcohol, which carries real health risks and can become habit-forming even in moderate amounts, so use it with caution. Red wine extract is not safe in pregnancy — no amount of alcohol is considered safe during pregnancy.
If you're breastfeeding, alcohol passes into breast milk, so you'll need to avoid it or be very careful about timing and how much you take. Common side effects tied to the alcohol content include nausea, diarrhea, drowsiness, flushing, headaches, low blood sugar (hypoglycemia), trouble with coordination and walking, and indigestion.
If you're allergic to sulfites or yeast, or if you have a history of asthma, wine can trigger allergic reactions ranging from mild to severe — some people have even had anaphylaxis (a life-threatening reaction) from yeast in fermented beverages.
Meds to double-check
Major interaction found
Before you take this product, double-check with your pharmacist if you're on disulfiram (Antabuse) — this is a must-avoid combination. Also check if you take blood thinners like warfarin, pain relievers like aspirin, heart or transplant medications, seizure drugs, antibiotics like erythromycin, or flibanserin.
All of these have Major interactions with the alcohol in red wine extract.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.
Red wine extract may be worth considering if you're looking at it for heart health, bone density, or blood sugar support — though the evidence is still developing. Skip it if you take disulfiram, blood thinners, aspirin, certain heart medications, or seizure drugs without checking with your pharmacist first.
If you're pregnant, breastfeeding, or have asthma or sulfite sensitivity, talk to your doctor or pharmacist before starting.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 23, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Red Wine Extract 500 mg, straight from the product label.
| Brand | Swanson |
|---|---|
| Barcode (UPC) | 087614141176 |
| Net contents | 90 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Apr 23, 2024 |
| DSLD ID | 308730 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Red Wine Extract 500 mg by Swanson, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Red Wine Fruit Extract, Fresh | 500 mg | -- |
Other ingredients: Gelatin, Maltodextrin, Rice Bran, Silica, Magnesium Stearate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Swanson.com or call 1-800-437-4148
Formula
Red Wine Extract delivers all the health benefits of red wine in an alcohol free form Loaded with polyphenols for potent free radical protection
Red Wine Extract 500mg per capsule
Brand IP Statement(s)
Swanson Science-Backed Quality Since 1969
Suggested/Recommended/Usage/Directions
Suggested use: As a dietary supplement, take one capsule two times per day with water.
Precautions
Warning: For adults only. Keep out of reach of children.
Consult your healthcare provider before using this or any product if you are pregnant or nursing, taking medication or have a medical condition.
Do not use if seal is broken.
Storage
Store in a cool, dry place.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Formulation
Antioxidant support Standardized
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Red Wine Extract 500 mg by Swanson label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Red Wine Extract 500 mg by Swanson
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.
Red Wine Fruit Extract, Fresh
Interacts with926 drugs
Wine is an alcoholic beverage made from fermented grapes and is not a true dietary supplement or medicine. Despite popular claims about heart benefits...
Red Wine Fruit Extract, Fresh monograph & interactionsOther (inactive) ingredients: Gelatin, Maltodextrin, Rice Bran, Silica, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.
Red Wine Extract 500 mg by Swanson Drug Interactions
HelloPharmacist Interaction Report
Red Wine Extract 500 mg by Swanson contains alcohol from wine, and that alcohol interacts with a number of medications.
The most serious concern is with disulfiram (Antabuse), used to support alcohol abstinence — taking this product with disulfiram can trigger a severe disulfiram reaction and must be avoided entirely.
Read the full breakdown — every affected drug type, severity by severity
Other Major interactions include blood thinners like warfarin, where alcohol can either boost or reduce the drug's effect depending on how much and how often you drink; aspirin and similar pain relievers, which raise your risk of stomach bleeding when combined with alcohol; heart and transplant medications like cisapride and cyclosporine, which can be less effective or cause unsafe blood alcohol buildup; seizure medications like phenytoin, which alcohol can make less effective; antibiotics like erythromycin, which can raise blood alcohol levels; and flibanserin (Addyi) for low sexual desire, where alcohol causes a dangerous drop in blood pressure and fainting.
Although these interactions span 909 individual medications, the drug TYPES above capture the main ones. Run your exact medications through the checker on this page before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Red Wine Extract 500 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Red Wine Extract 500 mg interact with 926 drugs. Click any drug to see the details.
1 of the 1 ingredient in Red Wine Extract 500 mg interact with drugs. Each result below shows which ingredient is responsible. Red Wine Fruit Extract, Fresh
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Red Wine Extract 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Red Wine Fruit Extract, FreshHepatotoxic Drugs Major
Interaction Summary
Concomitant use of alcohol with hepatotoxic drugs may increase the risk of hepatotoxicity.
Read the full Red Wine Fruit Extract, Fresh + 6-mercaptopurine interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Red Wine Extract 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Red Wine Fruit Extract, FreshHepatotoxic Drugs Major
Interaction Summary
Concomitant use of alcohol with hepatotoxic drugs may increase the risk of hepatotoxicity.
Read the full Red Wine Fruit Extract, Fresh + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Red Wine Extract 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Red Wine Fruit Extract, FreshHepatotoxic Drugs Major
Interaction Summary
Concomitant use of alcohol with hepatotoxic drugs may increase the risk of hepatotoxicity.
Read the full Red Wine Fruit Extract, Fresh + Abacavir, Lamivudine interactionAbiraterone
How Abiraterone interacts with Red Wine Extract 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Red Wine Fruit Extract, FreshHepatotoxic Drugs Major
Interaction Summary
Concomitant use of alcohol with hepatotoxic drugs may increase the risk of hepatotoxicity.
Read the full Red Wine Fruit Extract, Fresh + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Red Wine Extract 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Red Wine Fruit Extract, FreshHepatotoxic Drugs Major
Interaction Summary
Concomitant use of alcohol with hepatotoxic drugs may increase the risk of hepatotoxicity.
Read the full Red Wine Fruit Extract, Fresh + Abiraterone Acetate interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Red Wine Extract 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Red Wine Fruit Extract, FreshAntidiabetes Drugs, Hepatotoxic Drugs Major
Interaction Summary
Concomitant use may interfere with blood glucose control.
Read the full Red Wine Fruit Extract, Fresh + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Red Wine Extract 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Red Wine Fruit Extract, FreshHepatotoxic Drugs, Antihypertensive Drugs Major
Interaction Summary
Concomitant use of alcohol with hepatotoxic drugs may increase the risk of hepatotoxicity.
Read the full Red Wine Fruit Extract, Fresh + Acebutolol interactionAcepromazineAtravet
How Acepromazine interacts with Red Wine Extract 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Red Wine Fruit Extract, FreshCns Depressants Major
Interaction Summary
Concomitant use may increase sedative and other adverse effects.
Read the full Red Wine Fruit Extract, Fresh + Acepromazine interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Red Wine Extract 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Red Wine Fruit Extract, FreshHepatotoxic Drugs Major
Interaction Summary
Concomitant use of alcohol with hepatotoxic drugs may increase the risk of hepatotoxicity.
Read the full Red Wine Fruit Extract, Fresh + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Red Wine Extract 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Red Wine Fruit Extract, FreshNonsteroidal Anti-inflammatory Drugs (nsaids), Hepatotoxic Drugs +1 Major
Interaction Summary
Concomitant use may increase the risk of gastrointestinal (GI) bleeding.
Read the full Red Wine Fruit Extract, Fresh + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Red Wine Extract 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Red Wine Fruit Extract, FreshAspirin, Hepatotoxic Drugs +1 Major
Interaction Summary
Concomitant use may increase the risk of gastrointestinal (GI) bleeding.
Read the full Red Wine Fruit Extract, Fresh + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Red Wine Extract 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Red Wine Fruit Extract, FreshHepatotoxic Drugs Major
Interaction Summary
Concomitant use of alcohol with hepatotoxic drugs may increase the risk of hepatotoxicity.
Read the full Red Wine Fruit Extract, Fresh + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Red Wine Extract 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Red Wine Fruit Extract, FreshHepatotoxic Drugs Major
Interaction Summary
Concomitant use of alcohol with hepatotoxic drugs may increase the risk of hepatotoxicity.
Read the full Red Wine Fruit Extract, Fresh + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Red Wine Extract 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Red Wine Fruit Extract, FreshHepatotoxic Drugs Major
Interaction Summary
Concomitant use of alcohol with hepatotoxic drugs may increase the risk of hepatotoxicity.
Read the full Red Wine Fruit Extract, Fresh + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Red Wine Extract 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Red Wine Fruit Extract, FreshHepatotoxic Drugs, Narcotic Drugs +1 Major
Interaction Summary
Concomitant use of alcohol with hepatotoxic drugs may increase the risk of hepatotoxicity.
Read the full Red Wine Fruit Extract, Fresh + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Red Wine Extract 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Red Wine Fruit Extract, FreshCns Depressants, Hepatotoxic Drugs +1 Major
Interaction Summary
Concomitant use may increase sedative and other adverse effects.
Read the full Red Wine Fruit Extract, Fresh + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Red Wine Extract 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Red Wine Fruit Extract, FreshNarcotic Drugs, Cns Depressants +1 Major
Interaction Summary
Concomitant use of large amounts of alcohol may decrease the metabolism of narcotic drugs.
Read the full Red Wine Fruit Extract, Fresh + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Red Wine Extract 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Red Wine Fruit Extract, FreshHepatotoxic Drugs, Narcotic Drugs +1 Major
Interaction Summary
Concomitant use of alcohol with hepatotoxic drugs may increase the risk of hepatotoxicity.
Read the full Red Wine Fruit Extract, Fresh + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Red Wine Extract 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Red Wine Fruit Extract, FreshCns Depressants, Hepatotoxic Drugs +1 Major
Interaction Summary
Concomitant use may increase sedative and other adverse effects.
Read the full Red Wine Fruit Extract, Fresh + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Red Wine Extract 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Red Wine Fruit Extract, FreshNarcotic Drugs, Cns Depressants +1 Major
Interaction Summary
Concomitant use of large amounts of alcohol may decrease the metabolism of narcotic drugs.
Read the full Red Wine Fruit Extract, Fresh + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Red Wine Extract 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Red Wine Fruit Extract, FreshHepatotoxic Drugs, Narcotic Drugs +1 Major
Interaction Summary
Concomitant use of alcohol with hepatotoxic drugs may increase the risk of hepatotoxicity.
Read the full Red Wine Fruit Extract, Fresh + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Red Wine Extract 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Red Wine Fruit Extract, FreshHepatotoxic Drugs Major
Interaction Summary
Concomitant use of alcohol with hepatotoxic drugs may increase the risk of hepatotoxicity.
Read the full Red Wine Fruit Extract, Fresh + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Red Wine Extract 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Red Wine Fruit Extract, FreshHepatotoxic Drugs Major
Interaction Summary
Concomitant use of alcohol with hepatotoxic drugs may increase the risk of hepatotoxicity.
Read the full Red Wine Fruit Extract, Fresh + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Red Wine Extract 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Red Wine Fruit Extract, FreshHepatotoxic Drugs Major
Interaction Summary
Concomitant use of alcohol with hepatotoxic drugs may increase the risk of hepatotoxicity.
Read the full Red Wine Fruit Extract, Fresh + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Red Wine Extract 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Red Wine Fruit Extract, FreshHepatotoxic Drugs, Cns Depressants +1 Major
Interaction Summary
Concomitant use of alcohol with hepatotoxic drugs may increase the risk of hepatotoxicity.
Read the full Red Wine Fruit Extract, Fresh + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Red Wine Extract 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Red Wine Fruit Extract, FreshHepatotoxic Drugs Major
Interaction Summary
Concomitant use of alcohol with hepatotoxic drugs may increase the risk of hepatotoxicity.
Read the full Red Wine Fruit Extract, Fresh + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Red Wine Extract 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Red Wine Fruit Extract, FreshHepatotoxic Drugs Major
Interaction Summary
Concomitant use of alcohol with hepatotoxic drugs may increase the risk of hepatotoxicity.
Read the full Red Wine Fruit Extract, Fresh + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Red Wine Extract 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Red Wine Fruit Extract, FreshHepatotoxic Drugs Major
Interaction Summary
Concomitant use of alcohol with hepatotoxic drugs may increase the risk of hepatotoxicity.
Read the full Red Wine Fruit Extract, Fresh + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Red Wine Extract 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Red Wine Fruit Extract, FreshHepatotoxic Drugs Major
Interaction Summary
Concomitant use of alcohol with hepatotoxic drugs may increase the risk of hepatotoxicity.
Read the full Red Wine Fruit Extract, Fresh + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Red Wine Extract 500 mg — through 1 ingredient. Tap an ingredient for the detail:
Red Wine Fruit Extract, FreshHepatotoxic Drugs Major
Interaction Summary
Concomitant use of alcohol with hepatotoxic drugs may increase the risk of hepatotoxicity.
Read the full Red Wine Fruit Extract, Fresh + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Red Wine Extract 500 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Red Wine Fruit Extract, Fresh
Aspirin
Concomitant use may increase the risk of gastrointestinal (GI) bleeding.
Concomitant use of aspirin with alcohol may increase the risk of GI bleeding.
Cisapride (Propulsid)
Concomitant use may increase blood alcohol levels and adverse effects.
Concomitant use of alcohol can increase blood alcohol levels and adverse effects. Also, red wine increases plasma cisapride concentrations, possibly by reducing metabolism.
Cns Depressants
Concomitant use may increase sedative and other adverse effects.
Concomitant use of alcohol with CNS depressants can increase sedative and other adverse effects, potentially through inhibition of the metabolism of certain CNS depressants.
Cyclosporine (Neoral, Sandimmune)
Red wine can reduce the levels and clinical effects of cyclosporine.
Red wine reduces plasma cyclosporine concentrations, possibly by reducing cyclosporine absorption. There is evidence the reduction in cyclosporine AUC by red wine is less in Asians (8% to 14%) than Caucasians (35% to 36%).
Disulfiram (Antabuse)
Concomitant use may cause a disulfiram reaction.
Disulfiram can cause a disulfiram reaction when taken with alcohol. Patients taking disulfiram should not consume any alcohol.
Erythromycin
Concomitant use may increase blood alcohol levels and adverse effects.
Concomitant use of erythromycin with alcohol can increase blood alcohol levels and adverse effects.
Felodipine (Plendil)
Consumption of red wine can rapidly increase felodipine levels and adverse effects.
Red wine taken on an empty stomach can cause "dose dumping" of extended-release felodipine, possibly by changing absorption or metabolism. Red wine can delay the appearance of felodipine in plasma until 4 hours after dosing and can rapidly increase its plasma concentration, producing peak serum levels 3 to 4 times higher than when felodipine is given with water. This can cause an increase in adverse effects 5 hours after dosing.
Flibanserin (Addyi)
Concomitant use increases the risk of severe hypotension and syncope.
Alcohol use is contraindicated in patients taking flibanserin due to the risk of severe hypotension and syncope.
Hepatotoxic Drugs
Concomitant use of alcohol with hepatotoxic drugs may increase the risk of hepatotoxicity.
Concomitant use of excessive amounts of alcohol with potentially hepatotoxic drugs can increase the risk of liver damage.
Monoamine Oxidase Inhibitors (Maois)
Concomitant use may cause hypertensive crisis.
Wine contains tyramine, which is metabolized by monoamine oxidase. Concurrent use of MAOIs with tyramine-containing beverages can lead to elevated levels of tyramine in the body. This can increase the effects of tyramine, which has been reported to cause hypertension, headache, and hypertensive crisis in numerous cases. Sensitivity to tyramine can increase up to 10-fold to 100-fold in people using an MAOI.
Nonsteroidal Anti-Inflammatory Drugs (Nsaids)
Concomitant use may increase the risk of gastrointestinal (GI) bleeding.
Concomitant use of NSAIDs with alcohol may increase the risk of GI bleeding.
Phenytoin (Dilantin)
Concomitant use may decrease the effectiveness of phenytoin.
Chronic, heavy alcohol use can induce the metabolism, reducing therapeutic effectiveness of phenytoin.
Warfarin (Coumadin)
Alcohol can alter the effects of warfarin, although the exact effect depends on the nature of alcohol consumption.
Acute alcohol intoxication can decrease metabolism and increase the effects of warfarin. In contrast, chronic, heavy alcohol use can induce metabolism of warfarin, reducing therapeutic effectiveness.
Acitretin (Soriatane)
Concomitant use increases the risk of long-term teratogenic effects.
Alcohol increases the transesterification of acitretin to etretinate, which is a teratogen that can remain in the body for years after discontinuation of acitretin. Patients of reproductive potential should avoid alcohol completely while taking acitretin and at least 2 months after discontinuation.
Antidiabetes Drugs
Concomitant use may interfere with blood glucose control.
Alcohol can impair gluconeogenesis and may increase the risk of acute hypoglycemia when used concomitantly with antidiabetes drugs. However, the carbohydrates in wine may also worsen glycemic control in patients with diabetes.
Antihypertensive Drugs
Theoretically, concomitant use may interfere with blood pressure control.
Clinical research suggests that consumption of alcohol can increase both systolic and diastolic blood pressure. However, acute alcohol intoxication can also increase the risk of hypotension and additive effects with antihypertensive drugs.
Bupropion (Wellbutrin)
Theoretically, concomitant use may increase the risk of adverse effects from alcohol.
In patients taking bupropion, there have been rare reports of adverse psychiatric events or reduced alcohol tolerance. Additionally, in chronic alcohol users, abrupt discontinuation of alcohol while taking bupropion may increase the risk of seizure.
Cefamandole (Mandol)
Concomitant use may cause a disulfiram-like reaction.
Cefamandole can cause a disulfiram-like reaction when taken with alcohol.
Cefoperazone (Cefobid)
Concomitant use may cause a disulfiram-like reaction.
Cefoperazone can cause a disulfiram-like reaction when taken with alcohol.
Cetirizine (Zyrtec)
Theoretically, concomitant use might increase the risk of CNS impairment.
Cetirizine may cause somnolence in some patients. There is some concern that taking cetirizine in conjunction with alcohol might reduce alertness and impair CNS performance.
Chlorpropamide (Diabinese)
Concomitant use may cause a disulfiram-like reaction.
Chlorpropamide can cause a disulfiram-like reaction when taken with alcohol.
Citalopram (Celexa)
Theoretically, concomitant use might increase the risk of adverse effects from alcohol.
Some case reports suggest that citalopram may reduce alcohol tolerance and increase the risk of adverse effects from alcohol.
Doxycycline (Vibramycin)
Chronic alcohol use might reduce the levels and clinical effects of doxycycline.
Although acute alcohol ingestion does not seem to significantly impact the pharmacokinetics of doxycycline, chronic alcohol ingestion has been shown to significantly reduce the half-life and serum concentration of doxycycline.
Eluxadoline (Viberzi)
Chronic or excessive alcohol use might increase the risk of pancreatitis from eluxadoline.
In clinical studies, the risk of pancreatitis with eluxadoline was increased in chronic alcohol users and in those with acute intake of 3 or more alcoholic beverages daily.
Griseofulvin (Fulvicin)
Concomitant use may cause a disulfiram-like reaction.
Griseofulvin can cause a disulfiram-like reaction, including tachycardia and facial flushing, when taken with alcohol.
Brand information
Manufacturer and brand details for Red Wine Extract 500 mg, from the product label.
Swanson
See all Swanson products- Name
- Swanson Health Products
- City
- Fargo
- State
- ND
- ZipCode
- 58104
- Phone Number
- 1-800-437-4148
- Web Address
- swanson.com
Red Wine Extract 500 mg by Swanson: Common Questions
Does Red Wine Extract 500 mg by Swanson interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm pregnant or breastfeeding?
What are the side effects?
Does this actually work for heart health or bone density?
Why can't I take this with disulfiram?
Is this safe if I drink alcohol normally?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Red Wine Extract 500 mg is safe with your meds?
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Red Wine Extract 500 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Red Wine Extract 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 73 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Wine 73 references
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC