Interactions on record — worth a quick check against your medications. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

ReStim DM Maximum Strength Ingredients & Drug Interactions

by Green Tree Laboratories

Tablet Or Pill Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

ReStim DM Maximum Strength is a dietary supplement by Green Tree Laboratories with 3 active ingredients. Its ingredients are commonly taken for athletic performance and endurance, high-intensity exercise capacity, reducing muscle fatigue.Based on those ingredients, 248 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are LJ100 Eurycoma longifolia extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of ReStim DM Maximum Strength by Green Tree Laboratories

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 3 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (1,700 mg) without saying how much of each component you get.

ReStim DM Maximum Strength contains three active ingredients. Beta-alanine is an amino acid that may support athletic and physical performance.

The product also includes a Proprietary Blend (a mixture of ingredients the label doesn't break down individually) and EnoStim, which we don't have data on. Additionally, there's LJ100 Eurycoma longifolia extract, a plant-based ingredient traditionally used to support sexual desire.

The tablet also contains standard inactive ingredients like cellulose, silica, and magnesium stearate to hold it together.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Male vitality and athletic performance support.
  • We looked for evidence on: Age-related testosterone deficiency, Athletic performance, Erectile dysfunction (ED), Male Infertility, Muscle strength, Physical performance — and 4 related terms.
  • The strongest evidence on file: Eurycoma Longifolia is rated "Possibly Effective" for Sexual desire (Natural Medicines).
  • Also on file: Beta-alanine is rated "Possibly Effective" for Athletic performance, Physical performance.
  • Also on file: Eurycoma Longifolia is rated "Possibly Ineffective" for Athletic performance.

Beta-alanine is rated Possibly Effective for athletic performance and physical performance — meaning there's some evidence it may help, but it's not conclusive. For cognitive decline, brain function, COPD, and menopausal symptoms, the evidence isn't established enough to rate.

Eurycoma longifolia extract is rated Possibly Effective for sexual desire, but Possibly Ineffective for athletic performance. For back pain, osteoporosis, and diabetes, there's not enough reliable evidence to know either way.

We have no effectiveness data on EnoStim.

The evidence, ingredient by ingredient Beta-alanine Eurycoma Longifolia

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Beta-alanine is generally well tolerated, but it commonly causes a harmless tingling sensation (paresthesia) — a pins-and-needles feeling that starts on the scalp within 20 minutes and spreads across the body, lasting about an hour. The intensity depends on dose; it's mild at lower amounts and more noticeable at higher ones.

You may also notice skin flushing. Beta-alanine hasn't been studied long-term at high doses, so caution is wise with extended use.

Avoid it during pregnancy and breastfeeding because there isn't enough safety information. Eurycoma longifolia extract is generally tolerated in short-term studies, but long-term safety is uncertain.

Because it may raise testosterone levels, there's a theoretical risk of testosterone-related side effects — acne, insulin resistance, and liver concerns — if levels go too high. Avoid it during pregnancy and breastfeeding due to insufficient safety data and possible hormonal effects.

Side effects, ingredient by ingredient Beta-alanine Eurycoma Longifolia

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Eurycoma Longifolia.
  • The most serious interaction on file is rated Moderate.
  • For scale: 248 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Double-check this product with your pharmacist or doctor if you take propranolol or other blood pressure and heart medications — Eurycoma longifolia can reduce how well they work. Also flag it if you're on testosterone supplements or therapy, or if you take any medications broken down by your liver (your pharmacist can identify these).

No interactions are documented for beta-alanine, and we have no data to check on EnoStim.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product may be worth considering if you're looking to support athletic performance or sexual desire and don't take propranolol or other medications affected by liver enzymes. However, if you're on any blood pressure medication, heart drug, testosterone therapy, or medications processed by your liver, you need to check with your pharmacist or doctor before starting it.

The tingling and flushing from beta-alanine are harmless but noticeable, and the long-term safety of sustained use isn't well studied. Talk it over with your own healthcare provider before adding this to your routine.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about ReStim DM Maximum Strength, straight from the product label.

Brand Green Tree Laboratories
Net contents 60 Tablet(s)
Market status On market
Date entered into DSLD Jan 22, 2021
DSLD ID 243086
Product type Other Combinations
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for ReStim DM Maximum Strength by Green Tree Laboratories, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Tablet(s)
Maximum serving Sizes:
2 Tablet(s)
Servings per container
30
IngredientAmount% DV
Beta-Alanine0 NP--
Proprietary Blend1700 mg--
EnoStim0 NP--
LJ100 Eurycoma longifolia extract0 NP--

Other ingredients: Cellulose, Silica, Stearic Acid, Croscarmellose Sodium, Magnesium Stearate, Hypromellose, Polyethylene Glycol, Titanium Dioxide, FD&C Blue #1, FD&C Blue #2

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take two (2) tablets daily. For daily maintenance, dose must be consistent.

Daily maintenance

Brand IP Statement(s)

EnoStim is a trademark of Nexira, Inc. LJ100 is a registered trademark of HP Ingredients

Precautions

Precautions: Use only as directed.

Do not take if pregnant or nursing.

Consult a health care professional before use, or if you are allergic to any listed ingredients.

For adult use only. Discontinue use two weeks prior to surgery.

Tamper evident. Do not use if seal is broken.

Keep out of reach of children.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent disease.

Formulation

Daily Maintenance This daily maintenance (DM) formula not only provides an instant improvement in libido, performance, and longevity - but also ensures strong sexual health and performance over time. Physician formulated Male enhancement complex

Improves performance Strengthens libido Increases firmness

4.6x Improvement in size & firmness Clinically shown ingredients A physician formulated, plant based blend of clinically proven ingredients, ReStimDM male enhancement complex was developed to improve performance while experiencing a more powerful and intense libido.

Quality Commitment

FDA Statement of Identity

Dietary Supplement

Formula

Evolution of the hardness score with EnoStim (EHS)

Seals/Symbols

MFG In USA GMP Quality Good Manufacturing Practice Certification

See for yourself

ReStim DM Maximum Strength by Green Tree Laboratories label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in ReStim DM Maximum Strength by Green Tree Laboratories

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Tablet(s) Dosage formTablet Or Pill Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

1700 mg per serving

Other (inactive) ingredients: Cellulose, Silica, Stearic Acid, Croscarmellose Sodium, Magnesium Stearate, Hypromellose, Polyethylene Glycol, Titanium Dioxide, FD&C Blue #1, FD&C Blue #2. These complete the product’s ingredient list but are not active constituents.

Interaction report

ReStim DM Maximum Strength by Green Tree Laboratories Drug Interactions

Want to check YOUR meds against ReStim DM Maximum Strength?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
248Drugs
3 Moderate 245 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in ReStim DM Maximum Strength with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

LJ100 Eurycoma longifolia extract5 drug types · 248 drugs

Propranolol (Inderal)

Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
A small clinical study in healthy persons shows that taking a single dose of a water-based Eurycoma longifolia extract 200 mg, in combination with a single dose of propranolol 80 mg, reduces the propranolol area under the curve (AUC) by 29%, reduces the peak concentration by 42%, and increases time to peak concentration by 86% when compared with control. Since the elimination half-life of propranolol did not change, it seems that Eurycoma longifolia alters the kinetics of propranolol by decreasing its absorption in the gut, and not by altering its metabolism. It is not known if separating administration will prevent this interaction.

Likelihood Probable Evidence A
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP1A2 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2A6 (Cyp2A6) Substrates

Theoretically, Eurycoma longifolia might increase levels of CYP2A6 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2A6 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, Eurycoma longifolia might increase levels of CYP2C19 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2C19 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Testosterone

Theoretically, Eurycoma longifolia may further increase levels of testosterone.
A clinical study in aging males with testosterone levels below 300 ng/dL shows that taking a specific water extract of Eurycoma longifolia roots (Physta; Biotropics Malaysia) 100-200 mg daily with breakfast for 12 weeks increases total testosterone levels by 8% to 11% when compared with placebo. It is unclear whether this increase would occur in individuals with normal testosterone levels.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for ReStim DM Maximum Strength, from the product label.

Green Tree Laboratories

See all Green Tree Laboratories products
Name
Green Tree Laboratories
Phone Number
877-697-9717
Web Address
greentreelabs.co
Pharmacist Counseling Corner

ReStim DM Maximum Strength by Green Tree Laboratories: Common Questions

Does ReStim DM Maximum Strength by Green Tree Laboratories interact with any medications?
Yes. Based on its ingredients, ReStim DM Maximum Strength has a known interaction with 248 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
ReStim DM Maximum Strength contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What's that tingling feeling I might get from beta-alanine?
That's paresthesia — a pins-and-needles sensation caused by beta-alanine. It's harmless and usually starts on your scalp about 20 minutes after you take it, then spreads across your body, lasting roughly an hour. It's more intense at higher doses and milder at lower ones, so it's not a sign something's wrong.
Can I take this while I'm pregnant or breastfeeding?
The safety data advises against both beta-alanine and the Eurycoma longifolia extract during pregnancy and breastfeeding. There isn't enough information to know it's safe, so talk with your doctor or pharmacist about whether this is right for you.
Does this actually improve athletic performance?
Beta-alanine is rated Possibly Effective for athletic and physical performance, meaning there's some evidence it may help, but results aren't guaranteed. Eurycoma longifolia is rated Possibly Ineffective for athletic performance, so it likely won't boost workouts.
Is this safe to take long-term?
Beta-alanine hasn't been well studied at high doses over the long term, so caution is wise if you plan to use it for months or years. Eurycoma longifolia is generally tolerated short-term in studies, but its long-term safety is uncertain.
What's EnoStim and does it interact with anything?
EnoStim is one of the active ingredients in this product, but we don't hold interaction or safety data for it. You won't find a separate breakdown of it on this page — ask your pharmacist if you have questions about what it is or how it might affect your medications.
Will this raise my testosterone?
Eurycoma longifolia extract may increase testosterone levels, especially in men with lower baseline levels. If your testosterone goes above normal, there's a risk of side effects like acne, insulin resistance, and liver concerns. If you're already on testosterone therapy or have concerns about hormone levels, check with your doctor first.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if ReStim DM Maximum Strength is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

ReStim DM Maximum Strength label
Sources

Sources & How We Checked

ReStim DM Maximum Strength's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 17 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Beta-alanine 13 references
  1. Harris RC, Tallon MJ, Dunnett M, et al. The absorption of orally supplied beta-alanine and its effect on muscle carnosine synthesis in human vastus lateralis. Amino Acids 2006;30:279-89.
  2. Hill CA, Harris RC, Kim HJ, et al. Influence of beta-alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity. Amino Acids 2007;32:225-33.
  3. Bellinger PM, Minahan CL. The effect of ß-alanine supplementation on cycling time trials of different length. Eur J Sport Sci 2016;16(7):829-36.
  4. Chung W, Shaw G, Anderson ME, et al. Effect of 10 week beta-alanine supplementation on competition and training performance in elite swimmers. Nutrients 2012;4(10):1441-53. PubMed
  5. Glenn JM, Gray M, Stewart R, et al. Incremental effects of 28 days of beta-alanine supplementation on high-intensity cycling performance and blood lactate in masters female cyclists. Amino Acids 2015;47(12):2593-600. PubMed
  6. Gross M, Bieri K, Hoppeler H, Norman B, Vogt M. Beta-alanine supplementation improves jumping power and affects severe-intensity performance in professional alpine skiers. Int J Sport Nutr Exerc Metab 2014;24(6):665-73. PubMed
  7. Howe ST, Bellinger PM, Driller MW, Shing CM, Fell JW. The effect of beta-alanine supplementation on isokinetic force and cycling performance in highly trained cyclists. Int J Sport Nutr Exerc Metab 2013;23(6):562-70. PubMed
  8. Sweeney KM, Wright GA, Glenn Brice A, Doberstein ST. The effect of beta-alanine supplementation on power performance during repeated sprint activity. J Strength Cond Res 2010;24(1):79-87.
  9. Décombaz J, Beaumont M, Vuichoud J, Bouisset F, Stellingwerff T. Effect of slow-release ß-alanine tablets on absorption kinetics and paresthesia. Amino Acids 2012;43(1):67-76. Erratum in: Amino Acids 2013;45(4):1015.
  10. Stellingwerff T, Anwander H, Egger A, et al. Effect of two ß-alanine dosing protocols on muscle carnosine synthesis and washout. Amino Acids 2012;42(6):2461-72. PubMed
  11. da Silva RP, de Oliveira LF, Saunders B, et al. Effects of ß-alanine and sodium bicarbonate supplementation on the estimated energy system contribution during high-intensity intermittent exercise. Amino Acids. 2019;51(1):83-96. PubMed
  12. Varanoske AN, Hoffman JR, Church DD, et al. Comparison of sustained-release and rapid-release ß-alanine formulations on changes in skeletal muscle carnosine and histidine content and isometric performance following a muscle-damaging protocol. Amino Acids. PubMed
  13. Perim P, Gobbi N, Duarte B, et al. Beta-alanine did not improve high-intensity performance throughout simulated road cycling. Eur J Sport Sci 2021. PubMed

See these in context on the Beta-alanine monograph →

Eurycoma Longifolia 4 references
  1. Salman SA, Amrah S, Wahab MS, et al. Modification of propranolol's bioavailability by Eurycoma longifolia water-based extract. J Clin Pharm Ther 2010;35:691-6. PubMed
  2. Tambi MI, Imran MK, Henkel RR. Standardised water-soluble extract of Eurycoma longifolia, Tongkat ali, as testosterone booster for managing men with late-onset hypogonadism? Andrologia 2011 Jun 15. doi: 10.1111/j.1439-0272.2011.01168.x. [Epub ahead of pri PubMed
  3. Han YM, Kim IS, Rehman SU, Choe K, Yoo HH. In vitro evaluation of the effects of Eurycoma longifolia extract on CYP-mediated drug metabolism. Evid Based Complement Alternat Med 2015;2015:631329.
  4. Chinnappan SM, George A, Pandey P, Narke G, Choudhary YK. Effect of Eurycoma longifolia standardised aqueous root extract-Physta ® on testosterone levels and quality of life in ageing male subjects: a randomised, double-blind, placebo-controlled multicent

See these in context on the Eurycoma Longifolia monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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