ReStim DM Maximum Strength Ingredients & Drug Interactions
What is this page for?
First and foremost: checking ReStim DM Maximum Strength against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
ReStim DM Maximum Strength is a dietary supplement by Green Tree Laboratories with 3 active ingredients. Its ingredients are commonly taken for athletic performance and endurance, high-intensity exercise capacity, reducing muscle fatigue.Based on those ingredients, 248 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are LJ100 Eurycoma longifolia extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against ReStim DM Maximum Strength by Green Tree Laboratories
Ask about any prescription or over-the-counter medication and we check it for interactions with ReStim DM Maximum Strength by Green Tree Laboratories — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of ReStim DM Maximum Strength by Green Tree Laboratories
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
ReStim DM Maximum Strength contains three active ingredients. Beta-alanine is an amino acid that may support athletic and physical performance.
The product also includes a Proprietary Blend (a mixture of ingredients the label doesn't break down individually) and EnoStim, which we don't have data on. Additionally, there's LJ100 Eurycoma longifolia extract, a plant-based ingredient traditionally used to support sexual desire.
The tablet also contains standard inactive ingredients like cellulose, silica, and magnesium stearate to hold it together.
Does it work?
Moderate evidence
Beta-alanine is rated Possibly Effective for athletic performance and physical performance — meaning there's some evidence it may help, but it's not conclusive. For cognitive decline, brain function, COPD, and menopausal symptoms, the evidence isn't established enough to rate.
Eurycoma longifolia extract is rated Possibly Effective for sexual desire, but Possibly Ineffective for athletic performance. For back pain, osteoporosis, and diabetes, there's not enough reliable evidence to know either way.
We have no effectiveness data on EnoStim.
How safe is it?
Well-documented data
Beta-alanine is generally well tolerated, but it commonly causes a harmless tingling sensation (paresthesia) — a pins-and-needles feeling that starts on the scalp within 20 minutes and spreads across the body, lasting about an hour. The intensity depends on dose; it's mild at lower amounts and more noticeable at higher ones.
You may also notice skin flushing. Beta-alanine hasn't been studied long-term at high doses, so caution is wise with extended use.
Avoid it during pregnancy and breastfeeding because there isn't enough safety information. Eurycoma longifolia extract is generally tolerated in short-term studies, but long-term safety is uncertain.
Because it may raise testosterone levels, there's a theoretical risk of testosterone-related side effects — acne, insulin resistance, and liver concerns — if levels go too high. Avoid it during pregnancy and breastfeeding due to insufficient safety data and possible hormonal effects.
Meds to double-check
Moderate interaction found
Double-check this product with your pharmacist or doctor if you take propranolol or other blood pressure and heart medications — Eurycoma longifolia can reduce how well they work. Also flag it if you're on testosterone supplements or therapy, or if you take any medications broken down by your liver (your pharmacist can identify these).
No interactions are documented for beta-alanine, and we have no data to check on EnoStim.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product may be worth considering if you're looking to support athletic performance or sexual desire and don't take propranolol or other medications affected by liver enzymes. However, if you're on any blood pressure medication, heart drug, testosterone therapy, or medications processed by your liver, you need to check with your pharmacist or doctor before starting it.
The tingling and flushing from beta-alanine are harmless but noticeable, and the long-term safety of sustained use isn't well studied. Talk it over with your own healthcare provider before adding this to your routine.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 22, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about ReStim DM Maximum Strength, straight from the product label.
| Brand | Green Tree Laboratories |
|---|---|
| Net contents | 60 Tablet(s) |
| Market status | On market |
| Date entered into DSLD | Jan 22, 2021 |
| DSLD ID | 243086 |
| Product type | Other Combinations |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for ReStim DM Maximum Strength by Green Tree Laboratories, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Beta-Alanine | 0 NP | -- |
| Proprietary Blend | 1700 mg | -- |
| EnoStim | 0 NP | -- |
| LJ100 Eurycoma longifolia extract | 0 NP | -- |
Other ingredients: Cellulose, Silica, Stearic Acid, Croscarmellose Sodium, Magnesium Stearate, Hypromellose, Polyethylene Glycol, Titanium Dioxide, FD&C Blue #1, FD&C Blue #2
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested Use: As a dietary supplement, take two (2) tablets daily. For daily maintenance, dose must be consistent.
Daily maintenance
Brand IP Statement(s)
EnoStim is a trademark of Nexira, Inc. LJ100 is a registered trademark of HP Ingredients
Precautions
Precautions: Use only as directed.
Do not take if pregnant or nursing.
Consult a health care professional before use, or if you are allergic to any listed ingredients.
For adult use only. Discontinue use two weeks prior to surgery.
Tamper evident. Do not use if seal is broken.
Keep out of reach of children.
Storage
Store in a cool, dry place.
FDA Disclaimer Statement
These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent disease.
Formulation
Daily Maintenance This daily maintenance (DM) formula not only provides an instant improvement in libido, performance, and longevity - but also ensures strong sexual health and performance over time. Physician formulated Male enhancement complex
Improves performance Strengthens libido Increases firmness
4.6x Improvement in size & firmness Clinically shown ingredients A physician formulated, plant based blend of clinically proven ingredients, ReStimDM male enhancement complex was developed to improve performance while experiencing a more powerful and intense libido.
Quality Commitment
FDA Statement of Identity
Dietary Supplement
Formula
Evolution of the hardness score with EnoStim (EHS)
Seals/Symbols
MFG In USA GMP Quality Good Manufacturing Practice Certification
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
ReStim DM Maximum Strength by Green Tree Laboratories label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in ReStim DM Maximum Strength by Green Tree Laboratories
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Tablet(s) Dosage formTablet Or Pill Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Blend
- › Beta-Alanine
- › EnoStim
- › LJ100 Eurycoma longifolia extract
Other (inactive) ingredients: Cellulose, Silica, Stearic Acid, Croscarmellose Sodium, Magnesium Stearate, Hypromellose, Polyethylene Glycol, Titanium Dioxide, FD&C Blue #1, FD&C Blue #2. These complete the product’s ingredient list but are not active constituents.
ReStim DM Maximum Strength by Green Tree Laboratories Drug Interactions
HelloPharmacist Interaction Report
ReStim DM Maximum Strength, made by Green Tree Laboratories, does interact with medications through its Eurycoma longifolia extract content.
The most serious interaction is Moderate: Eurycoma longifolia can reduce how well propranolol (a blood pressure and heart medication) works by lowering its levels in your blood. A small clinical study showed a single dose of the extract reduced propranolol levels by about 29%.
Read the full breakdown — every affected drug type, severity by severity
Eurycoma longifolia also has Minor interactions with several other medication types. It may theoretically increase levels of drugs broken down by your liver through CYP1A2, CYP2C19, and CYP2A6 pathways — though these effects haven't been proven in humans yet.
Additionally, if you take testosterone supplements or medications, Eurycoma longifolia may raise testosterone levels further, which could increase the risk of testosterone-related side effects like acne and insulin resistance.
Beta-alanine, the other active ingredient we could check, has no documented interactions. We could not check EnoStim, which is also in this product.
Altogether, these interactions span 248 individual medications. Use the search tool below to check your exact medications before starting this supplement.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against ReStim DM Maximum Strength?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in ReStim DM Maximum Strength interact with 248 drugs. Click any drug to see the details.
1 of the 3 ingredients in ReStim DM Maximum Strength interact with drugs. Each result below shows which ingredient is responsible. LJ100 Eurycoma longifolia extract
Hydrochlorothiazide, PropranololInderide
How Hydrochlorothiazide, Propranolol interacts with ReStim DM Maximum Strength — through 1 ingredient. Tap an ingredient for the detail:
Lj100 Eurycoma Longifolia ExtractPropranolol (inderal), Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
Read the full Lj100 Eurycoma Longifolia Extract + Hydrochlorothiazide, Propranolol interactionPropranololAngilol, Bedranol SR, Beta Prograne, Half Beta Prograne, Half-Inderal LA, Inderal +6 more
How Propranolol interacts with ReStim DM Maximum Strength — through 1 ingredient. Tap an ingredient for the detail:
Lj100 Eurycoma Longifolia ExtractPropranolol (inderal), Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
Read the full Lj100 Eurycoma Longifolia Extract + Propranolol interactionPropranolol HydrochlorideHemangeol
How Propranolol Hydrochloride interacts with ReStim DM Maximum Strength — through 1 ingredient. Tap an ingredient for the detail:
Lj100 Eurycoma Longifolia ExtractPropranolol (inderal), Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
Read the full Lj100 Eurycoma Longifolia Extract + Propranolol Hydrochloride interactionAbrocitinibCibinqo
How Abrocitinib interacts with ReStim DM Maximum Strength — through 1 ingredient. Tap an ingredient for the detail:
Lj100 Eurycoma Longifolia ExtractCytochrome P450 2c19 (cyp2c19) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels of CYP2C19 substrates.
Read the full Lj100 Eurycoma Longifolia Extract + Abrocitinib interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with ReStim DM Maximum Strength — through 1 ingredient. Tap an ingredient for the detail:
Lj100 Eurycoma Longifolia ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 Eurycoma Longifolia Extract + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with ReStim DM Maximum Strength — through 1 ingredient. Tap an ingredient for the detail:
Lj100 Eurycoma Longifolia ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 Eurycoma Longifolia Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with ReStim DM Maximum Strength — through 1 ingredient. Tap an ingredient for the detail:
Lj100 Eurycoma Longifolia ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 Eurycoma Longifolia Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with ReStim DM Maximum Strength — through 1 ingredient. Tap an ingredient for the detail:
Lj100 Eurycoma Longifolia ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 Eurycoma Longifolia Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with ReStim DM Maximum Strength — through 1 ingredient. Tap an ingredient for the detail:
Lj100 Eurycoma Longifolia ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 Eurycoma Longifolia Extract + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with ReStim DM Maximum Strength — through 1 ingredient. Tap an ingredient for the detail:
Lj100 Eurycoma Longifolia ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 Eurycoma Longifolia Extract + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with ReStim DM Maximum Strength — through 1 ingredient. Tap an ingredient for the detail:
Lj100 Eurycoma Longifolia ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 Eurycoma Longifolia Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with ReStim DM Maximum Strength — through 1 ingredient. Tap an ingredient for the detail:
Lj100 Eurycoma Longifolia ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 Eurycoma Longifolia Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with ReStim DM Maximum Strength — through 1 ingredient. Tap an ingredient for the detail:
Lj100 Eurycoma Longifolia ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 Eurycoma Longifolia Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with ReStim DM Maximum Strength — through 1 ingredient. Tap an ingredient for the detail:
Lj100 Eurycoma Longifolia ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 Eurycoma Longifolia Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with ReStim DM Maximum Strength — through 1 ingredient. Tap an ingredient for the detail:
Lj100 Eurycoma Longifolia ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 Eurycoma Longifolia Extract + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with ReStim DM Maximum Strength — through 1 ingredient. Tap an ingredient for the detail:
Lj100 Eurycoma Longifolia ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 Eurycoma Longifolia Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with ReStim DM Maximum Strength — through 1 ingredient. Tap an ingredient for the detail:
Lj100 Eurycoma Longifolia ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 Eurycoma Longifolia Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with ReStim DM Maximum Strength — through 1 ingredient. Tap an ingredient for the detail:
Lj100 Eurycoma Longifolia ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 Eurycoma Longifolia Extract + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with ReStim DM Maximum Strength — through 1 ingredient. Tap an ingredient for the detail:
Lj100 Eurycoma Longifolia ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 Eurycoma Longifolia Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with ReStim DM Maximum Strength — through 1 ingredient. Tap an ingredient for the detail:
Lj100 Eurycoma Longifolia ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 Eurycoma Longifolia Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with ReStim DM Maximum Strength — through 1 ingredient. Tap an ingredient for the detail:
Lj100 Eurycoma Longifolia ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 Eurycoma Longifolia Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with ReStim DM Maximum Strength — through 1 ingredient. Tap an ingredient for the detail:
Lj100 Eurycoma Longifolia ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 Eurycoma Longifolia Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with ReStim DM Maximum Strength — through 1 ingredient. Tap an ingredient for the detail:
Lj100 Eurycoma Longifolia ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 Eurycoma Longifolia Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with ReStim DM Maximum Strength — through 1 ingredient. Tap an ingredient for the detail:
Lj100 Eurycoma Longifolia ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 Eurycoma Longifolia Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with ReStim DM Maximum Strength — through 1 ingredient. Tap an ingredient for the detail:
Lj100 Eurycoma Longifolia ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 Eurycoma Longifolia Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with ReStim DM Maximum Strength — through 1 ingredient. Tap an ingredient for the detail:
Lj100 Eurycoma Longifolia ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 Eurycoma Longifolia Extract + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with ReStim DM Maximum Strength — through 1 ingredient. Tap an ingredient for the detail:
Lj100 Eurycoma Longifolia ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 Eurycoma Longifolia Extract + Acetaminophen, Chlorpheniramine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylephrine, SalicylamideRhinogesic, Rhinogesic JR
How Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interacts with ReStim DM Maximum Strength — through 1 ingredient. Tap an ingredient for the detail:
Lj100 Eurycoma Longifolia ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 Eurycoma Longifolia Extract + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylpropanolamineAlumadrine, Conex, Sinadrin Max Strength, Sinulin
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine interacts with ReStim DM Maximum Strength — through 1 ingredient. Tap an ingredient for the detail:
Lj100 Eurycoma Longifolia ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 Eurycoma Longifolia Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with ReStim DM Maximum Strength — through 1 ingredient. Tap an ingredient for the detail:
Lj100 Eurycoma Longifolia ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Lj100 Eurycoma Longifolia Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionEach ingredient & the kinds of drugs it affects
For each ingredient in ReStim DM Maximum Strength with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
LJ100 Eurycoma longifolia extract
Propranolol (Inderal)
Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
A small clinical study in healthy persons shows that taking a single dose of a water-based Eurycoma longifolia extract 200 mg, in combination with a single dose of propranolol 80 mg, reduces the propranolol area under the curve (AUC) by 29%, reduces the peak concentration by 42%, and increases time to peak concentration by 86% when compared with control. Since the elimination half-life of propranolol did not change, it seems that Eurycoma longifolia alters the kinetics of propranolol by decreasing its absorption in the gut, and not by altering its metabolism. It is not known if separating administration will prevent this interaction.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP1A2 enzymes. This effect has not been reported in humans.
Cytochrome P450 2A6 (Cyp2A6) Substrates
Theoretically, Eurycoma longifolia might increase levels of CYP2A6 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2A6 enzymes. This effect has not been reported in humans.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, Eurycoma longifolia might increase levels of CYP2C19 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2C19 enzymes. This effect has not been reported in humans.
Testosterone
Theoretically, Eurycoma longifolia may further increase levels of testosterone.
A clinical study in aging males with testosterone levels below 300 ng/dL shows that taking a specific water extract of Eurycoma longifolia roots (Physta; Biotropics Malaysia) 100-200 mg daily with breakfast for 12 weeks increases total testosterone levels by 8% to 11% when compared with placebo. It is unclear whether this increase would occur in individuals with normal testosterone levels.
Brand information
Manufacturer and brand details for ReStim DM Maximum Strength, from the product label.
Green Tree Laboratories
See all Green Tree Laboratories products- Name
- Green Tree Laboratories
- Phone Number
- 877-697-9717
- Web Address
- greentreelabs.co
ReStim DM Maximum Strength by Green Tree Laboratories: Common Questions
Does ReStim DM Maximum Strength by Green Tree Laboratories interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What's that tingling feeling I might get from beta-alanine?
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What's EnoStim and does it interact with anything?
Will this raise my testosterone?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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The Full Monographs Behind ReStim DM Maximum Strength’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Beta-alanine
Beta-alanine is an amino acid taken mostly by athletes to raise muscle carnosine, which may help buffer acid and reduce fatigue during short, high-intensity exercise. The evidence is moderat...
Read the full Beta-alanine monograph → Herb & supplement monographEurycoma Longifolia
Interacts with 248 drugsEurycoma longifolia (tongkat ali) is a Southeast Asian herb most popular for supporting testosterone, libido, and male fertility, with some small human studies suggesting possible benefits....
Read the full Eurycoma Longifolia monograph →Sources & How We Checked
ReStim DM Maximum Strength's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 17 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Beta-alanine 13 references
- Harris RC, Tallon MJ, Dunnett M, et al. The absorption of orally supplied beta-alanine and its effect on muscle carnosine synthesis in human vastus lateralis. Amino Acids 2006;30:279-89.
- Hill CA, Harris RC, Kim HJ, et al. Influence of beta-alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity. Amino Acids 2007;32:225-33.
- Bellinger PM, Minahan CL. The effect of ß-alanine supplementation on cycling time trials of different length. Eur J Sport Sci 2016;16(7):829-36.
- Chung W, Shaw G, Anderson ME, et al. Effect of 10 week beta-alanine supplementation on competition and training performance in elite swimmers. Nutrients 2012;4(10):1441-53. PubMed
- Glenn JM, Gray M, Stewart R, et al. Incremental effects of 28 days of beta-alanine supplementation on high-intensity cycling performance and blood lactate in masters female cyclists. Amino Acids 2015;47(12):2593-600. PubMed
- Gross M, Bieri K, Hoppeler H, Norman B, Vogt M. Beta-alanine supplementation improves jumping power and affects severe-intensity performance in professional alpine skiers. Int J Sport Nutr Exerc Metab 2014;24(6):665-73. PubMed
- Howe ST, Bellinger PM, Driller MW, Shing CM, Fell JW. The effect of beta-alanine supplementation on isokinetic force and cycling performance in highly trained cyclists. Int J Sport Nutr Exerc Metab 2013;23(6):562-70. PubMed
- Sweeney KM, Wright GA, Glenn Brice A, Doberstein ST. The effect of beta-alanine supplementation on power performance during repeated sprint activity. J Strength Cond Res 2010;24(1):79-87.
- Décombaz J, Beaumont M, Vuichoud J, Bouisset F, Stellingwerff T. Effect of slow-release ß-alanine tablets on absorption kinetics and paresthesia. Amino Acids 2012;43(1):67-76. Erratum in: Amino Acids 2013;45(4):1015.
- Stellingwerff T, Anwander H, Egger A, et al. Effect of two ß-alanine dosing protocols on muscle carnosine synthesis and washout. Amino Acids 2012;42(6):2461-72. PubMed
- da Silva RP, de Oliveira LF, Saunders B, et al. Effects of ß-alanine and sodium bicarbonate supplementation on the estimated energy system contribution during high-intensity intermittent exercise. Amino Acids. 2019;51(1):83-96. PubMed
- Varanoske AN, Hoffman JR, Church DD, et al. Comparison of sustained-release and rapid-release ß-alanine formulations on changes in skeletal muscle carnosine and histidine content and isometric performance following a muscle-damaging protocol. Amino Acids. PubMed
- Perim P, Gobbi N, Duarte B, et al. Beta-alanine did not improve high-intensity performance throughout simulated road cycling. Eur J Sport Sci 2021. PubMed
Eurycoma Longifolia 4 references
- Salman SA, Amrah S, Wahab MS, et al. Modification of propranolol's bioavailability by Eurycoma longifolia water-based extract. J Clin Pharm Ther 2010;35:691-6. PubMed
- Tambi MI, Imran MK, Henkel RR. Standardised water-soluble extract of Eurycoma longifolia, Tongkat ali, as testosterone booster for managing men with late-onset hypogonadism? Andrologia 2011 Jun 15. doi: 10.1111/j.1439-0272.2011.01168.x. [Epub ahead of pri PubMed
- Han YM, Kim IS, Rehman SU, Choe K, Yoo HH. In vitro evaluation of the effects of Eurycoma longifolia extract on CYP-mediated drug metabolism. Evid Based Complement Alternat Med 2015;2015:631329.
- Chinnappan SM, George A, Pandey P, Narke G, Choudhary YK. Effect of Eurycoma longifolia standardised aqueous root extract-Physta ® on testosterone levels and quality of life in ageing male subjects: a randomised, double-blind, placebo-controlled multicent
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC