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Dietary supplement

Black Walnut/Wormwood Ingredients & Drug Interactions

by L.A. Naturals

Black Walnut/Wormwood label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Black Walnut/Wormwood against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Black Walnut/Wormwood is a dietary supplement by L.A. Naturals with 2 active ingredients. Its ingredients are commonly taken for intestinal parasites and worms, digestive complaints, antimicrobial and antifungal support.Based on those ingredients, 50 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are certified organic Wormwood. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Black Walnut/Wormwood by L.A. Naturals

Ask about any prescription or over-the-counter medication and we check it for interactions with Black Walnut/Wormwood by L.A. Naturals — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Black Walnut/Wormwood by L.A. Naturals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 2 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label doesn't break down how much of each component you get.

This liquid contains two active ingredients: certified organic fresh (green) black walnut and certified organic wormwood, combined in a proprietary blend. The liquid base also includes grain alcohol and deionized water.

Black walnut is traditionally used for its potential effects on heart health and wound healing, though the evidence for these uses is not well established. Wormwood has been used for digestive complaints, depression, joint discomfort, and other conditions, but again, the reliable evidence supporting these uses is limited.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

The label doesn't state a purpose we can grade — see each ingredient's own graded uses on its monograph instead.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for both ingredients in this product is insufficient — we don't have solid data showing they work for their traditional uses. Black walnut's effectiveness for coronary heart disease and wound healing hasn't been reliably established.

Wormwood's effectiveness for biliary disorders, Crohn disease, depression, indigestion, and osteoarthritis also lacks sufficient reliable evidence. If you're considering this product for a specific health concern, talk with your pharmacist or doctor about what the actual evidence shows.

The evidence, ingredient by ingredient Black Walnut Wormwood

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Black walnut is generally well tolerated when the nut itself is used, but this product contains the leaf and/or hull, which are high in tannins and may cause gastrointestinal upset, skin irritation, or discoloration. Black walnut should be avoided during pregnancy and breastfeeding — there isn't enough safety information.

Wormwood carries more serious concerns: it contains thujone, a neurotoxin that can cause nausea, vomiting, muscle aches, and in rare cases kidney damage, muscle breakdown, or seizures. Wormwood should not be used during pregnancy because it may stimulate the uterus, and it should be avoided while breastfeeding.

Tree nuts, including black walnuts, can trigger allergic reactions in sensitive people — this is a major food allergen.

Side effects, ingredient by ingredient Black Walnut Wormwood

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Wormwood.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: seizure medications.
  • For scale: 50 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Anyone taking anticonvulsants (seizure medications) should check with their pharmacist first — wormwood may interfere with how these drugs work. If you take any other prescription medications, use the search tool on this page to verify there are no concerns before you start.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This is a short-term product only — long-term safety data are limited for both ingredients. If you take anticonvulsants or any other prescription medication, check them with the tool on this page first.

Pregnant or breastfeeding women should not use it. Talk to your pharmacist before starting, especially if you have a tree nut allergy, take seizure medication, or have liver or kidney concerns.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2014.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Black Walnut/Wormwood, straight from the product label.

Brand L.A. Naturals
Barcode (UPC) 641356166318
Net contents 1 fl. Oz.; 30 mL
Market status On market
Date entered into DSLD Jul 25, 2014
DSLD ID 34909
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Black Walnut/Wormwood by L.A. Naturals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.67 mL
Maximum serving Sizes:
1.33 mL
Servings per container
30
UPC/BARCODE
641356166318
IngredientAmount% DV
Proprietary Blend0 NP--
certified organic fresh (green) Black Walnut0 NP--
certified organic Wormwood0 NP--

Other ingredients: Grain Alcohol, deionized Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement

** These statements have not been evaluated by the FDA. This product is not intended to diagnose, cure, treat, or prevent any disease.

Suggested/Recommended/Usage/Directions

SUGGESTED USE: 20-40 drops in water or juice, 2-3 times daily, or as needed.

Shake well before using.

Precautions

WARNING: Keep out of the reach of children.

May Contain Tree Nuts.

General Statements

Plant # K-0001604

MADE IN THE USA

FAST ABSORPTION MEDICINAL BOTANICALS HERB FORMULA IN ALCOHOL

Supports Normal Intestinal Ecology **

Amount Per Serving 680 mg Herb Weight Equivalence

Herb Strength Ratio 1:1.5

Seals/Symbols

L.a.(TM)

K PARVE

FDA Statement of Identity

DIETARY SUPPLEMENT

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Black Walnut/Wormwood by L.A. Naturals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Black Walnut/Wormwood label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Black Walnut/Wormwood by L.A. Naturals

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size0.67 mL Dosage formLiquid Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Other (inactive) ingredients: Grain Alcohol, Deionized Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Black Walnut/Wormwood by L.A. Naturals Drug Interactions

Want to check YOUR meds against Black Walnut/Wormwood?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
50Drugs
50 Moderate

Ingredients driving the most interactions

certified organic Wormwood 50

Individual Drug Interactions

The ingredients in Black Walnut/Wormwood interact with 50 drugs. Click any drug to see the details.

1 of the 2 ingredients in Black Walnut/Wormwood interact with drugs. Each result below shows which ingredient is responsible. certified organic Wormwood

Each ingredient & the kinds of drugs it affects

For each ingredient in Black Walnut/Wormwood with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

certified organic Wormwood1 drug type · 50 drugs

Anticonvulsants

Theoretically, taking wormwood might interfere with the effects of anticonvulsant drugs.
Thujone, a constituent of wormwood, has convulsant effects.

Likelihood Possible Evidence D
certified organic Wormwood full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Black Walnut/Wormwood, from the product label.

L.A. Naturals

See all L.A. Naturals products
Name
Palko Services
Street Address
4991 W. US Hwy 20
City
Michigan City
State
IN
ZipCode
46360
Pharmacist Counseling Corner

Black Walnut/Wormwood by L.A. Naturals: Common Questions

Does Black Walnut/Wormwood by L.A. Naturals interact with any medications?
Yes. Based on its ingredients, Black Walnut/Wormwood has a known interaction with 50 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Black Walnut/Wormwood contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I use this if I'm pregnant or breastfeeding?
No. Black walnut should be avoided during pregnancy and breastfeeding because there isn't enough safety data. Wormwood is unsafe during pregnancy because it may stimulate the uterus, and should be avoided while breastfeeding. Talk to your doctor before considering any herbal product in pregnancy or lactation.
What are the side effects?
The most common side effects are from the tannins in black walnut's leaf and hull — gastrointestinal upset and skin irritation. Wormwood may cause nausea, vomiting, and muscle aches. In rare cases, wormwood has caused kidney damage, muscle breakdown, and seizures. Stop and contact your doctor or poison control if you experience severe symptoms.
I have a tree nut allergy. Is this safe for me?
Black walnut is a tree nut and is a major food allergen in the US. If you have a tree nut allergy, this product could trigger a reaction. Do not use it without talking to your doctor or allergist first.
How long can I safely take this?
The data show that short-term use may be acceptable, but long-term safety hasn't been well studied for either ingredient. This is not a product to take indefinitely — ask your pharmacist about an appropriate duration for your situation.
Does this actually work for heart health or digestion?
The evidence isn't there yet. Black walnut's effect on heart health and wound healing is not well established, and wormwood's usefulness for digestion and other conditions lacks solid reliable evidence. If you're using it for a specific health goal, have that conversation with your pharmacist or doctor.
I take seizure medication. Can I use this?
No — not without checking with your doctor or pharmacist first. Wormwood may interfere with how anticonvulsants work. Please use the medication search tool on this page or call us before you start.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Black Walnut/Wormwood is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Black Walnut/Wormwood label
Go deeper

The Full Monographs Behind Black Walnut/Wormwood’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Black Walnut

Black walnut is a tree whose green hulls are traditionally used as a natural antiparasitic and digestive remedy, but solid human evidence for these uses is lacking. It contains a compound ca...

Read the full Black Walnut monograph → Herb & supplement monograph

Wormwood

Interacts with 50 drugs

Wormwood is a very bitter herb traditionally used to stimulate appetite and ease digestion, and it has early research interest in Crohn's disease. It contains thujone, which can be toxic in...

Read the full Wormwood monograph →
Sources

Sources & How We Checked

Black Walnut/Wormwood's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 13 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Black Walnut 3 references
  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  3. Food and Drug Administration. Food Allergen Labeling and Consumer Protection Act of 2004 (FALCPA); Public Law 108-282, Title II. Accessed on May 19, 2021. Available at: https://www.fda.gov/food/food-allergensgluten-free-guidance-documents-regulatory-infor

See these in context on the Black Walnut monograph →

Wormwood 10 references
  1. Weisbord SD, Soule JB, Kimmel PL. Poison on line-acute renal failure caused by oil of wormwood purchased through the internet. N Engl J Med 1997;337:825-7. PubMed
  2. Gambelunghe C, Melai P. Absinthe: enjoying a new popularity among young people? Forensic Sci Int 2002;130:183-6.
  3. Hold KM, Sirisoma NS, Casida JE. Detoxification of alpha- and beta-Thujones (the active ingredients of absinthe): site specificity and species differences in cytochrome P450 oxidation in vitro and in vivo. Chem Res Toxicol 2001;14:589-95.
  4. Lachenmeier DW, Walch SG, Padosch SA, Kroner LU. Absinthe--a review. Crit Rev Food Sci Nutr 2006;46:365-77.
  5. Padosch SA, Lachenmeier DW, Kroner LU. Absinthism: a fictitious 19th century syndrome with present impact. Subst Abuse Treat Prev Policy 2006;1:14. PubMed
  6. Lachenmeier DW, Emmert J, Kuballa T, Sartor G. Thujone--cause of absinthism? Forensic Sci Int 2006;158:1-8. PubMed
  7. Dettling, A., Grass, H., Schuff, A., Skopp, G., Strohbeck-Kuehner, P., and Haffner, H. T. Absinthe: attention performance and mood under the influence of thujone. J Stud.Alcohol 2004;65(5):573-581. PubMed
  8. Benezet-Mazuecos, J. and de la Fuente, A. Electrocardiographic findings after acute absinthe intoxication. Int J Cardiol. 11-10-2006;113(2):e48-e50. PubMed
  9. El Makrini NI, Hassam B. Artemisia absinthium: burning plant! Pan Afr Med J. 2016 Jan 22;23:10. PubMed
  10. Kocaoglu C, Ozel A. Persistent metabolic acidosis and severe diarrhoea due to Artemisia absinthium poisoning. J Pak Med Assoc. 2014 Sep;64(9):1081-3.

See these in context on the Wormwood monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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