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Dietary supplement

Slippery Elm Ingredients & Drug Interactions

by L.A. Naturals

Slippery Elm label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Slippery Elm against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Slippery Elm is a dietary supplement by L.A. Naturals with 1 active ingredient. Its ingredients are commonly taken for sore throat and cough, heartburn and acid reflux, digestive upset and ibs.Based on those ingredients, 2,022 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are ethically wild harvested Slippery Elm. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Slippery Elm by L.A. Naturals

Ask about any prescription or over-the-counter medication and we check it for interactions with Slippery Elm by L.A. Naturals — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Slippery Elm by L.A. Naturals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.

This product contains one active ingredient: ethically wild harvested slippery elm. Slippery elm is the inner bark of a tree, traditionally used to soothe the digestive tract.

The liquid form also contains grain alcohol and deionized water as inactive ingredients.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Slippery Elm product and its label doesn't state a use — see Slippery Elm's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for slippery elm isn't well established in our data. We have insufficient reliable evidence to rate it for cancer, constipation, cough, diarrhea, or inflammatory bowel disease.

If you're thinking about taking it for one of these reasons, talk with your pharmacist or doctor about what the research actually shows and whether it makes sense for your situation.

The evidence, ingredient by ingredient Slippery Elm

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Slippery elm is generally well tolerated for short-term use, though high-quality safety data are limited. The main concern we have is allergic reaction — contact dermatitis (a skin rash from touching it), urticaria (hives), and reactions to the pollen have been reported.

There isn't enough reliable data on safety during pregnancy or while breastfeeding, so caution is advised if you're in either situation.

Side effects, ingredient by ingredient Slippery Elm

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Slippery Elm.
  • The most serious interaction on file is rated Moderate.
  • For scale: 2,023 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, check any oral medications you're on — prescription and over-the-counter. Slippery elm's mucilage can slow how your body absorbs them, which may make them less effective.

Talk to your pharmacist about timing your doses to stay safe.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Slippery elm may be worth considering if you're looking for a traditional throat or digestive soother, but the evidence for specific conditions isn't strong in our data. The biggest thing to watch is that it might slow down absorption of your oral medications.

Check your exact medications before starting, and space out doses if your pharmacist gives you the all clear.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2014.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Slippery Elm, straight from the product label.

Brand L.A. Naturals
Barcode (UPC) 641356045118
Net contents 1 fl. Oz.; 30 mL
Market status On market
Date entered into DSLD Jul 25, 2014
DSLD ID 35147
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Kosher
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Slippery Elm by L.A. Naturals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
2 mL
Servings per container
30
UPC/BARCODE
641356045118
IngredientAmount% DV
ethically wild harvested Slippery Elm0 NP--

Other ingredients: Grain Alcohol, deionized Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

SUGGESTED USE: 30-60 drops in water or juice, 2-3 times daily, or as needed.

Shake well before using.

Precautions

WARNING: Keep out of the reach of children.

General Statements

Plant # K-0001604

MADE IN THE USA

FAST ABSORPTION MEDICINAL BOTANICALS SINGLE HERB IN ALCOHOL

200 mg Herb Weight Equivalence

Herb Strength Ratio 1:5

Seals/Symbols

L.a.(TM)

K PARVE

FDA Statement of Identity

DIETARY SUPPLEMENT

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Slippery Elm by L.A. Naturals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Slippery Elm label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Slippery Elm by L.A. Naturals

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container30 Amounts shown are per serving.

Ethically wild harvested Slippery Elm

Interacts with
2,022 drugs
0 NP per serving

Slippery elm is a traditional herbal remedy made from the inner bark of a North American elm tree, used mainly to soothe sore throats and irritated di...

Ethically wild harvested Slippery Elm monograph & interactions

Other (inactive) ingredients: Grain Alcohol, Deionized Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Slippery Elm by L.A. Naturals Drug Interactions

Want to check YOUR meds against Slippery Elm?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,022Drugs
2,022 Moderate

Ingredients driving the most interactions

ethically wild harvested Slippery Elm 2,022

Individual Drug Interactions

The ingredients in Slippery Elm interact with 2,022 drugs. Click any drug to see the details.

1 of the 1 ingredient in Slippery Elm interact with drugs. Each result below shows which ingredient is responsible. ethically wild harvested Slippery Elm

Each ingredient & the kinds of drugs it affects

For each ingredient in Slippery Elm with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

ethically wild harvested Slippery Elm1 drug type · 2,022 drugs

Oral Drugs

Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Slippery elm inner bark contains mucilage, which may interfere with the absorption of orally administered drugs.

Likelihood Possible Evidence D
ethically wild harvested Slippery Elm full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Slippery Elm, from the product label.

L.A. Naturals

See all L.A. Naturals products
Name
Palko Services
Street Address
4991 W. US Hwy 20
City
Michigan City
State
IN
ZipCode
46360
Pharmacist Counseling Corner

Slippery Elm by L.A. Naturals: Common Questions

Does Slippery Elm by L.A. Naturals interact with any medications?
Yes. Based on its ingredients, Slippery Elm has a known interaction with 2,022 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Slippery Elm contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take slippery elm if I'm pregnant?
There isn't enough reliable safety data to know either way. The caution in our data advises against it during pregnancy, so talk with your doctor or pharmacist for personalized advice before you use it.
What's the main side effect I should watch for?
Allergic reactions are the main concern — contact dermatitis (a skin rash from touching it), hives, and reactions to the pollen have been reported. If you have a history of plant allergies, mention it to your pharmacist.
Is slippery elm proven to work for sore throats or digestive issues?
We don't have sufficient reliable evidence to say it works for those uses. It's traditionally used that way, but the science doesn't back it up strongly in our data.
Is this safe to use long-term?
High-quality safety data for long-term use are limited. It's generally well tolerated for short-term use, so talk with your pharmacist if you're thinking about taking it regularly for months at a time.
Can I take this while I'm breastfeeding?
There's too little information on safety while breastfeeding, so caution is advised. Talk with your doctor or pharmacist before you use it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Slippery Elm is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Slippery Elm label
Go deeper

The Full Monographs Behind Slippery Elm’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Slippery Elm

Interacts with 2,022 drugs

Slippery elm is a traditional herbal remedy made from the inner bark of a North American elm tree, used mainly to soothe sore throats and irritated digestive tracts. Its mucilage can coat an...

Read the full Slippery Elm monograph →
Sources

Sources & How We Checked

Slippery Elm's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Slippery Elm 3 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  3. Czarnecki D, Nixon R, Bekhor P, and et al. Delayed prolonged contact urticaria from the elm tree. Contact Dermatitis 1993;28:196-197. PubMed

See these in context on the Slippery Elm monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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