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Dietary supplement

Resveratrol 150 mg Red Grape Ingredients & Drug Interactions

by EZ Melts

Tablet Or Pill Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Resveratrol 150 mg Red Grape is a dietary supplement by EZ Melts with 1 active ingredient. Its ingredients are commonly taken for heart and blood vessel health, antioxidant support, anti-aging.Based on those ingredients, 822 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Trans-Resveratrol 99% powdered extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Resveratrol 150 mg Red Grape by EZ Melts

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: trans-resveratrol 99% powdered extract (150 mg per tablet), derived from red grape. Resveratrol is a plant compound found naturally in grapes, berries, and wine that your body uses as an antioxidant.

The tablet also contains inactive ingredients — mannitol, xylitol, natural flavors and colors, magnesium stearate, malic acid, stearic acid, silica, and monk fruit extract — which are binders, sweeteners, and flow agents that help hold the tablet together and make it taste better.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Resveratrol's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Promotes anti-aging and heart health.
  • We looked for evidence on: Aging skin, Cardiovascular disease (CVD), Hypercholesterolemia, Hypertension, Vascular function, Oxidative stress.
  • The closest evidence on file: Resveratrol is rated "Possibly Ineffective" for Cardiovascular disease (CVD) (Natural Medicines).
  • Also on file: Resveratrol is rated "Possibly Ineffective" for Hypercholesterolemia.
  • Also on file: Resveratrol is rated "Insufficient Reliable Evidence To Rate" for Aging skin, Hypertension.

The evidence for resveratrol's effectiveness is mixed. It's rated possibly effective for obesity and allergic rhinitis (hay fever) — meaning there's some research support, but we need more data to be sure.

For cardiovascular disease and high cholesterol (hypercholesterolemia), the evidence points toward it being possibly ineffective, so it's unlikely to help with those conditions based on what we know now.

The evidence, ingredient by ingredient Resveratrol

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Resveratrol from food sources is well tolerated overall. When taken orally at higher doses as a supplement, it's generally well tolerated, though some people report diarrhea, gastrointestinal discomfort, and loose stools — mainly digestive side effects.

One case of a skin rash was reported in a trial, which resolved two weeks after stopping. The safety data advises against concentrated resveratrol supplements during pregnancy and while breastfeeding, as there isn't enough information to know they're safe at these times.

If you're pregnant, nursing, or planning to become pregnant, talk with your doctor or pharmacist about whether this product is right for you.

Side effects, ingredient by ingredient Resveratrol

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Resveratrol.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 823 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you're on blood thinners or antiplatelet drugs like warfarin, aspirin, or clopidogrel — resveratrol may increase bleeding risk. Also check if you take any medications broken down by CYP2C19, CYP1A2, CYP3A4, or CYP2E1 liver enzymes, since resveratrol may raise their levels.

The medication checker on this page can help identify which of your drugs fall into these groups.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Resveratrol may be worth considering if you're interested in possibly supporting weight or seasonal allergy symptoms, though the evidence is still growing. The main caution is if you take blood thinners or antiplatelet drugs — this supplement may raise your bleeding risk.

Anyone on medications metabolized by the liver should also check their exact drugs with a pharmacist before starting. Talk it over with your own doctor or pharmacist before adding this to your routine.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Resveratrol 150 mg Red Grape, straight from the product label.

Brand EZ Melts
Barcode (UPC) 851989007609
Net contents 60 Fast Melting Tablet(s)
Market status On market
Date entered into DSLD Feb 23, 2022
DSLD ID 260921
Product type Non-nutrient/non-botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Resveratrol 150 mg Red Grape by EZ Melts, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Tablet(s)
Maximum serving Sizes:
2 Tablet(s)
Servings per container
30
UPC/BARCODE
851989007609
IngredientAmount% DV
Trans-Resveratrol 99% powdered extract150 mg--

Other ingredients: Mannitol, Xylitol, Natural flavors and colors, Magnesium Stearate, Malic Acid, Stearic Acid, Silica, Monk Fruit extract

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Zero Sugar Gluten-Free Non-GMO

Vegan

Promotes Anti-Aging & Heart Health

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take 2 tablets a day or as recommended by your healthcare professional. Allow tablet to dissolve in mouth. No water necessary.

Precautions

If you are pregnant, nursing or taking medication, consult your healthcare professional before use.

Keep out of reach of children.

Storage

Store at room temperature.

Brand IP Statement(s)

EZ Melts Dissolvable Vitamins

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

See for yourself

Resveratrol 150 mg Red Grape by EZ Melts label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Resveratrol 150 mg Red Grape by EZ Melts

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Tablet(s) Dosage formTablet Or Pill Servings per container30 Amounts shown are per serving.

Trans-Resveratrol 99% powdered extract

Interacts with
822 drugs
150 mg per serving

Resveratrol is a plant compound found in red grapes, berries, and peanuts that is popular for heart health, anti-aging, and antioxidant support. While...

Trans-Resveratrol 99% powdered extract monograph & interactions

Other (inactive) ingredients: Mannitol, Xylitol, Natural flavors and colors, Magnesium Stearate, Malic Acid, Stearic Acid, Silica, Monk Fruit extract. These complete the product’s ingredient list but are not active constituents.

Interaction report

Resveratrol 150 mg Red Grape by EZ Melts Drug Interactions

Want to check YOUR meds against Resveratrol 150 mg Red Grape?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
822Drugs
822 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Resveratrol 150 mg Red Grape with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Trans-Resveratrol 99% powdered extract5 drug types · 822 drugs

Anticoagulant/Antiplatelet Drugs

Resveratrol may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Resveratrol seems to have antiplatelet effects.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, resveratrol might increase levels of drugs metabolized by CYP1A2.
In vitro research shows that resveratrol can inhibit CYP1A2 enzymes. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, resveratrol might increase levels of drugs metabolized by CYP2C19.
In vitro research shows that resveratrol can inhibit CYP2C19 enzymes. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2E1 (Cyp2E1) Substrates

Resveratrol might increase levels of drugs metabolized by CYP2E1.
In vitro research suggests that resveratrol inhibits CYP2E1 isoenzyme. Also, a pharmacokinetic study shows that taking resveratrol 500 mg daily for 10 days prior to taking a single dose of chlorzoxazone 250 mg increases the maximum concentration of chlorzoxazone by about 54%, the area under the curve of chlorzoxazone by about 72%, and the half-life of chlorzoxazone by about 35%. Chlorzoxazone is used as a probe drug for CYP2E1.

Likelihood Probable Evidence B
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, resveratrol might increase levels of drugs metabolized by CYP3A4.
In vitro research shows that resveratrol can inhibit the CYP3A4 enzyme. However, clinical research shows that taking resveratrol 3000 mg daily for 8 weeks does not necessitate dose adjustments to medications metabolized by CYP3A4.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Resveratrol 150 mg Red Grape, from the product label.

EZ Melts

See all EZ Melts products
Name
Solara Labs
Street Address
5105 NW 159th St.
City
Miami Gardens
State
FL
ZipCode
33014
Phone Number
1-786-747-4950
Web Address
www.ezmelts.com
Pharmacist Counseling Corner

Resveratrol 150 mg Red Grape by EZ Melts: Common Questions

Does Resveratrol 150 mg Red Grape by EZ Melts interact with any medications?
Yes. Based on its ingredients, Resveratrol 150 mg Red Grape has a known interaction with 822 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Resveratrol 150 mg Red Grape contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is resveratrol safe to take if I'm pregnant or breastfeeding?
The safety data advises against concentrated resveratrol supplements during pregnancy and breastfeeding because there isn't enough information to know they're safe at these times. If you're pregnant, nursing, or planning pregnancy, talk with your doctor or pharmacist about whether this product is right for you.
What are the most common side effects?
The most common side effects reported from oral resveratrol are digestive — diarrhea, gastrointestinal discomfort, and loose stools, especially at higher doses. These tend to be mild. One case of a skin rash was reported in a trial but resolved after stopping.
Will this help me lose weight?
Resveratrol is rated possibly effective for obesity, meaning there's some research support but we need more data to be confident. It may be worth trying as part of a broader approach, but don't rely on it as your main tool.
Can it help with hay fever?
Resveratrol is rated possibly effective for allergic rhinitis (hay fever), so there is research suggesting it may help some people, though the evidence isn't definitive yet.
Does this product contain fillers?
Yes — the inactive ingredients include mannitol, xylitol, magnesium stearate, malic acid, stearic acid, silica, and monk fruit extract, which are binders, sweeteners, and flow agents that help form and flavor the tablet.
How much resveratrol does each tablet contain?
Each tablet contains 150 mg of trans-resveratrol 99% powdered extract derived from red grape.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Resveratrol 150 mg Red Grape is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Resveratrol 150 mg Red Grape label
Go deeper

The Full Monographs Behind Resveratrol 150 mg Red Grape’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Resveratrol 150 mg Red Grape's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 24 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Resveratrol 24 references
  1. Soleas GJ, Diamandis EP, Goldberg DM. Resveratrol: a molecule whose time has come? And gone? Clin Biochem 1997;30:91-113.
  2. Pace-Asciak CR, Rounova O, Hahn SE, et al. Wines and grape juices as modulators of platelet aggregation in healthy human subjects. Clin Chim Acta 1996;246:163-82. PubMed
  3. Bertelli AA, Giovannini L, Bernini W, et al. Antiplatelet activity of cis-resveratrol. Drugs Exp Clin Res 1996;22:61-3.
  4. Pace-Asciak CR, Hahn S, Diamandis EP, et al. The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: implications for protection against coronary heart disease. Clin Chim Acta 1995;235:207-19.
  5. Bertelli A, Bertelli AA, Gozzini A, Giovannini L. Plasma and tissue resveratrol concentrations and pharmacological activity. Drugs Exp Clin Res 1998;24:133-8.
  6. Bertelli AA, Giovannini L, Giannessi D, et al. Antiplatelet activity of synthetic and natural resveratrol in red wine. Int J Tissue React 1995;17:1-3.
  7. Piver B, Berthou F, Dreano Y, Lucas D. Inhibition of CYP3A, CYP1A and CYP2E1 activities by resveratrol and other non volatile red wine components. Toxicol Lett 2001;125:83-91. PubMed
  8. Chang, T. K., Chen, J., and Lee, W. B. Differential inhibition and inactivation of human CYP1 enzymes by trans-resveratrol: evidence for mechanism-based inactivation of CYP1A2. J.Pharmacol.Exp.Ther. 2001;299(3):874-882.
  9. Dobrydneva, Y., Williams, R. L., and Blackmore, P. F. trans-Resveratrol inhibits calcium influx in thrombin-stimulated human platelets. Br.J.Pharmacol. 1999;128(1):149-157.
  10. Kirk, R. I., Deitch, J. A., Wu, J. M., and Lerea, K. M. Resveratrol decreases early signaling events in washed platelets but has little effect on platalet in whole food. Blood Cells Mol.Dis. 2000;26(2):144-150.
  11. Zbikowska, H. M. and Olas, B. Antioxidants with carcinostatic activity (resveratrol, vitamin E and selenium) in modulation of blood platelet adhesion. J Physiol Pharmacol. 2000;51(3):513-520.
  12. Olas, B., Wachowicz, B., Saluk-Juszczak, J., and Zielinski, T. Effect of resveratrol, a natural polyphenolic compound, on platelet activation induced by endotoxin or thrombin. Thromb.Res 8-15-2002;107(3-4):141-145. PubMed
  13. Yu, C., Shin, Y. G., Kosmeder, J. W., Pezzuto, J. M., and van Breemen, R. B. Liquid chromatography/tandem mass spectrometric determination of inhibition of human cytochrome P450 isozymes by resveratrol and resveratrol-3-sulfate. Rapid Commun.Mass Spectro PubMed
  14. Ma, Z. H. and Ma, Q. Y. Resveratrol: a medical drug for acute pancreatitis. World J Gastroenterol. 6-7-2005;11(21):3171-3174. PubMed
  15. la, Porte C., Voduc, N., Zhang, G., Seguin, I., Tardiff, D., Singhal, N., and Cameron, D. W. Steady-State pharmacokinetics and tolerability of trans-resveratrol 2000 mg twice daily with food, quercetin and alcohol (ethanol) in healthy human subjects. Cli PubMed
  16. Brown, V. A., Patel, K. R., Viskaduraki, M., Crowell, J. A., Perloff, M., Booth, T. D., Vasilinin, G., Sen, A., Schinas, A. M., Piccirilli, G., Brown, K., Steward, W. P., Gescher, A. J., and Brenner, D. E. Repeat dose study of the cancer chemopreventive
  17. Pendurthi, U. R., Williams, J. T., and Rao, L. V. Resveratrol, a polyphenolic compound found in wine, inhibits tissue factor expression in vascular cells : A possible mechanism for the cardiovascular benefits associated with moderate consumption of wine. PubMed
  18. Chachay VS, Macdonald GA, Martin JH, Whitehead JP, O'Moore-Sullivan TM, Lee P, Franklin M, Klein K, Taylor PJ, Ferguson M, Coombes JS, Thomas GP, Cowin GJ, Kirkpatrick CM, Prins JB, Hickman IJ. Resveratrol does not benefit patients with nonalcoholic fatty
  19. Bedada SK, Neerati P. Resveratrol Pretreatment Affects CYP2E1 Activity of Chlorzoxazone in Healthy Human Volunteers. Phytother Res. 2016;30(3):463-8. PubMed
  20. Lin CT, Sun XY, Lin AX. Supplementation with high-dose trans-resveratrol improves ultrafiltration in peritoneal dialysis patients: a prospective, randomized, double-blind study. Ren Fail. 2016;38(2):214-21. PubMed
  21. Li Q, Yang G, Xu H, Tang S, Lee WY. Effects of resveratrol supplementation on bone quality: a systematic review and meta-analysis of randomized controlled trials. BMC Complement Med Ther 2021;21(1):214. PubMed
  22. McCreary MR, Schnell PM, Rhoda DA. Randomized double-blind placebo-controlled proof-of-concept trial of resveratrol for outpatient treatment of mild coronavirus disease (COVID-19). Sci Rep 2022;12(1):10978. PubMed
  23. Abdelhaleem IA, Brakat AM, Adayel HM, Asla MM, Rizk MA, Aboalfetoh AY. The effects of resveratrol on glycemic control and cardiometabolic parameters in patients with T2DM: A systematic review and meta-analysis. Med Clin (Barc) 2022;158(12):576-585. PubMed
  24. Badaoui A. Allergic contact dermatitis to resveratrol and Scutellaria baicalensis root extract in a cosmetic product. Contact Dermatitis 2022.

See these in context on the Resveratrol monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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