No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

S. Thermophilus Ingredients & Drug Interactions

by Custom Probiotics

S. Thermophilus label
See full label image
Powder Category: Non-nutrient/non-botanical
No known interaction
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking S. Thermophilus against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line No known interaction

S. Thermophilus is a dietary supplement by Custom Probiotics with 1 active ingredient. Its ingredients are commonly taken for digestive health, lactose intolerance, diarrhea prevention and support.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

Jump to a section

HelloPharmacist Scorecard of S. Thermophilus by Custom Probiotics

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.

This product contains one active ingredient: S. thermophilus (Streptococcus thermophilus), a live probiotic bacterium. There are no other inactive ingredients listed.

Probiotics like S. thermophilus are beneficial bacteria meant to support gut health and balance.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Streptococcus Thermophilus's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: dairy-free probiotic powder digestive health.
  • We looked for evidence on: Antibiotic-associated diarrhea, Clostridioides difficile infection, Constipation, Irritable bowel syndrome (IBS), Pouchitis, Rotaviral diarrhea — and 4 related terms.
  • The closest evidence on file: Streptococcus Thermophilus is rated "Insufficient Reliable Evidence To Rate" for Antibiotic-associated diarrhea (Natural Medicines).
  • Also on file: Streptococcus Thermophilus is rated "Insufficient Reliable Evidence To Rate" for Constipation, Diarrhea, Ulcerative colitis, Irritable bowel syndrome (IBS), and more.

The evidence for S. thermophilus is limited. Our data shows insufficient reliable evidence to rate it for antibiotic-associated diarrhea, bacterial vaginosis, nonalcoholic fatty liver disease (NAFLD), constipation, diabetes, or diabetic kidney disease (diabetic nephropathy).

That doesn't mean it doesn't work — it means large, high-quality studies haven't yet established what it can or can't do for these conditions. If you're thinking about it for a specific reason, talk with your doctor about whether the evidence is there.

The evidence, ingredient by ingredient Streptococcus Thermophilus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

S. thermophilus is generally well tolerated in healthy people. The main safety concern is for anyone with a weakened immune system — whether from illness, age, premature birth, or medical devices like central catheters — where live probiotic microorganisms carry a small theoretical risk of infection.

For pregnancy, the data shows it's possibly safe, but probiotics from food are considered more established than supplements; talk with your doctor or midwife before taking this supplement during pregnancy. Lactation safety data isn't on file.

Side effects, ingredient by ingredient Streptococcus Thermophilus

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for S. thermophilus. That said, always run your full medication list through the checker on this page or ask your pharmacist — probiotics may behave differently in individual patients, especially those with compromised immunity or serious illness.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

Custom Probiotics S. Thermophilus is a single-strain probiotic powder with no documented drug interactions.

It's generally well tolerated in healthy people, though the evidence for specific health claims is still limited. If you have a weakened immune system, are severely ill, or are pregnant or breastfeeding, check with your doctor before starting.

Your own doctor or pharmacist can help you decide if this supplement fits your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 21, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about S. Thermophilus, straight from the product label.

Brand Custom Probiotics
Net contents 0 Not Present
Market status On market
Date entered into DSLD Sep 21, 2018
DSLD ID 181335
Product type Non-nutrient/non-botanical
Supplement form Powder
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Children (All), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for S. Thermophilus by Custom Probiotics, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.1 Gram(s)
Maximum serving Sizes:
1.6 Gram(s)
IngredientAmount% DV
S. thermophilus0 NP--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions of use: Dissolve 1-2 scoops (enclosed) of the dairy-free probiotic powder in one glass of purified water and drink it. Do this first thing in the morning and/or at bedtime.

Please read enclosed dosage suggestion or visit www.customprobiotics.com

Storage

Bottles should be kept tightly closed and stored in the refrigerator to retain maximum potency.

Formulation

Does not contain: Artificial colors, flavors, preservatives, sugar, gluten, soy, wheat or FOS.

Dairy free probiotic powder

General Statements

Ultra potency

400 billion cfu's per gram

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

S. Thermophilus by Custom Probiotics label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

S. Thermophilus label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in S. Thermophilus by Custom Probiotics

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.1 Gram(s) Dosage formPowder Amounts shown are per serving.

S. thermophilus

No known
interactions
0 NP per serving

Streptococcus thermophilus is a friendly bacterium used as a probiotic, often combined with other strains in yogurt and supplements. It is generally w...

S. thermophilus monograph & interactions
Interaction report

S. Thermophilus by Custom Probiotics Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in S. Thermophilus. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for S. Thermophilus, from the product label.

Custom Probiotics

See all Custom Probiotics products
Name
Custom Probiotics, Inc.
City
Glendale
State
California
ZipCode
91214
Phone Number
(800) 219-8405
Web Address
www.customprobiotics.com
Pharmacist Counseling Corner

S. Thermophilus by Custom Probiotics: Common Questions

Does S. Thermophilus by Custom Probiotics interact with any medications?
We do not currently list a known interaction for the mapped ingredients in S. Thermophilus. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
S. Thermophilus contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is S. thermophilus safe if I have a weak immune system?
People with weakened immune systems — from illness, medical devices, prematurity, or other causes — should talk with their doctor first. Live probiotic bacteria carry a small theoretical risk of infection in this population, though it's rare in people with intact immune defenses.
Can I take this while pregnant?
The data shows S. thermophilus is possibly safe in pregnancy, but probiotics from food are considered more established than supplements. Talk with your doctor or midwife before starting this supplement — they can weigh the evidence for your specific situation.
Will this help my constipation or diarrhea?
Our data shows insufficient reliable evidence to rate S. thermophilus for either condition. That means the research isn't yet clear on whether it works. Your doctor can help you figure out if it's worth trying or if another approach makes more sense.
Does this product have fillers or other inactive ingredients?
No other inactive ingredients are listed for this product — it's just the S. thermophilus powder.
Can I take this with my medications?
No interactions are documented in our data for this ingredient. Run your exact medication list through the checker on this page, or ask your pharmacist to be sure — they can review your full picture.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if S. Thermophilus is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

S. Thermophilus label
Go deeper

The Full Monographs Behind S. Thermophilus’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Streptococcus Thermophilus

Streptococcus thermophilus is a friendly bacterium used as a probiotic, often combined with other strains in yogurt and supplements. It is generally well tolerated in healthy people and may...

Read the full Streptococcus Thermophilus monograph →
Sources

Sources & How We Checked

S. Thermophilus's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 21 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Streptococcus Thermophilus 21 references
  1. Saxelin M, Chuang NH, Chassy B, et al. Lactobacilli and bacteremia in southern Finland 1989-1992. Clin Infect Dis 1996;22:564-6. PubMed
  2. Tynkkynen S, Singh KV, Varmanen P. Vancomycin resistance factor of Lactobacillus rhamnosus GG in relation to enterococcal vancomycin resistance (van) genes. Int J Food Microbiol 1998;41:195-204. PubMed
  3. Klein G, Zill E, Schindler R, et al. Peritonitis associated with vancomycin-resistant Lactobacillus rhamnosus in a continuous ambulatory peritoneal dialysis patient; organism identification, antibiotic therapy, and case report. J Clin Microbiol 1998;36:
  4. Kalima P, Masterton RG, Roddie PH, et al. Lactobacillus rhamnosus infection in a child following bone marrow transplant. J Infect 1996;32:165-7. PubMed
  5. Goldin BR. Health Benefits of probiotics. Br J Nutr 1998;80:S203-7. DOI
  6. Rautio M, Jousimies-Somer H, Kauma H, et al. Liver abscess due to Lactobacillus rhamnosus strain indistinguishable from L. rhamnosus strain GG. Clin Infect Dis 1999;28:1159-60.
  7. MacGregor G, Smith AJ, Thakker B, Kinsella J. Yoghurt biotherapy: contraindicated in immunosuppressed patients? Postgrad Med J 2002;78:366-7. PubMed
  8. Land MH, Rouster-Stevens K, Woods CR, et al. Lactobacillus sepsis associated with probiotic therapy. Pediatrics 2005;115:178-81.
  9. De Groote MA, Frank DN, Dowell E, et al. Lactobacillus rhamnosus GG bacteremia associated with probiotic use in a child with short gut syndrome. Pediatr Infect Dis J 2005;24:278-80. PubMed
  10. Vahabnezhad E, Mochon AB, Wozniak LJ, Ziring DA. Lactobacillus bacteremia associated with probiotic use in a pediatric patient with ulcerative colitis. J Clin Gastroenterol. 2013;47(5):437-9. PubMed
  11. Dolatkhah N, Hajifaraji M, Abbasalizadeh F, Aghamohammadzadeh N, Mehrabi Y, Abbasi MM. Is there a value for probiotic supplements in gestational diabetes mellitus? A randomized clinical trial. J Health Popul Nutr. 2015;33:25. PubMed
  12. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  13. Sendil S, Shrimanker I, Mansoora Q, Goldman J, Nookala VK. Lactobacillus rhamnosus bacteremia in an immunocompromised renal transplant patient. Cureus. 2020;12(2):e6887. PubMed
  14. Albarillo FS, Shah U, Joyce C, Slade D. Lactobacillus rhamnosus Infection: A single-center 4-year descriptive analysis. J Glob Infect Dis. 2020;12(3):119-123. PubMed
  15. Pasala S, Singer L, Arshad T, Roach K. Lactobacillus endocarditis in a healthy patient with probiotic use. IDCases. 2020;22:e00915. PubMed
  16. Agrawal S, Tuchman ES, Bruce MJ, Theodorou ME. Fatal Lactobacillus endocarditis in a patient with transcatheter aortic valve replacement. BMJ Case Rep. 2020;13(11):e236835.
  17. Antoun M, Hattab Y, Akhrass FA, Hamilton LD. Uncommon pathogen, Lactobacillus, causing infective endocarditis: Case report and review. Case Rep Infect Dis. 2020;2020:8833948. PubMed
  18. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  19. Franko B, Vaillant M, Recule C, Vautrin E, et al. Lactobacillus paracasei endocarditis in a consumer of probiotics. Med Mal Infect. 2013;43(4):171-3. PubMed
  20. Campbell RE, Miller A, Afroze A. Native valve endocarditis secondary to Lactobacillus paracasei bacteremia. Consultant. 2020;60(9):27-8. DOI
  21. Kato K, Funabashi N, Takaoka H, et al. Lactobacillus paracasei endocarditis in a consumer of probiotics with advanced and severe bicuspid aortic valve stenosis complicated with diffuse left ventricular mid-layer fibrosis. Int J Cardiol. 2016;224:157-161. PubMed

See these in context on the Streptococcus Thermophilus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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